公开(公告)号：US10992106B1

公开(公告)日：2021-04-27

申请号：US16414297

申请日：2019-05-16

Applicant: STC.UNM

Inventor： Marek Osinski ,  Gennady A. Smolyakov

IPC: H01S5/062 ,  H01S5/06 ,  H01S5/04 ,  H01S5/10 ,  H01S5/042

Abstract: A method for generating single optical pulses of picosecond-range duration with suppressed transient emission tails.

公开(公告)号：US10914800B2

公开(公告)日：2021-02-09

申请号：US15743527

申请日：2016-07-11

Applicant: STC.UNM ,  Victor Acosta ,  Andrejs Jarmola ,  Lykourgos Bougas ,  Dmitry Budker

Inventor： Victor Acosta ,  Andrejs Jarmola ,  Lykourgos Bougas ,  Dmitry Budker

IPC: G01R33/32 ,  G01N24/08 ,  G01N24/10 ,  G01R33/30 ,  G01R33/44 ,  G01R33/46 ,  G01R33/60 ,  C30B33/08 ,  C30B29/04 ,  C30B33/12

Abstract: Technologies relating to a magnetic resonance spectrometer are disclosed. The magnetic resonance spectrometer may include a doped nanostructured crystal. By nanostructuring the surface of the crystal, the sensor-sample contact area of the crystal can be increased. As a result of the increased sensor-sample contact area, the output fluorescence signal emitted from the crystal is also increased, with corresponding reductions in measurement acquisition time and requisite sample volumes.

公开(公告)号：US20200368461A1

公开(公告)日：2020-11-26

申请号：US16892900

申请日：2020-06-04

Applicant: STC.UNM

Inventor： Nicola Jeanne Maynard ,  Hugh D.C. Smyth

IPC: A61M15/00 ,  A61M11/00

Abstract: A dry powder delivery device may be configured to provide micronized dry powder particles to airways of a user. The device may include a cylindrical container delimiting a chamber containing at least one magnetically-responsive object, a motor external to said chamber, a magnet external to the chamber and rotatably coupled with the motor, and an outflow member configured to direct airflow to a user. The magnetically-responsive object may be coated with micronized dry powder particles, and the motor may be operable to rotate the magnet about an axis. Rotation of the magnet creates a magnetic field that causes the magnetically-responsive object to move in response to the magnetic field and collide with a side wall of the container to deaggregate the dry powder particles and aerosolize the dry powder in the chamber.

公开(公告)号：US10827946B2

公开(公告)日：2020-11-10

申请号：US15756221

申请日：2016-08-31

Applicant: STC.UNM

Inventor： Shihoko Kimura-Ohba ,  Laurel Sillerud

IPC: A61B5/055 ,  A61B6/03 ,  G06T7/48 ,  A61B5/00 ,  G06T7/00 ,  G01R33/563

Abstract: The present invention concerns a method for determining whether brain regions of interest having reversible or irreversible pathology. The method includes acquiring over a predetermined period of time a plurality of magnetic resonance imaging (MRI) images for each brain region of interest; analyzing the MRI images to obtain quantitative measurements of the fractional anisotropy (FA) for each brain region of interest and determining that brain regions of interest have reversible pathology when the measured FA increases and then decreases over the predetermined period of time.

公开(公告)号：US20200318197A1

公开(公告)日：2020-10-08

申请号：US16719497

申请日：2019-12-18

Applicant: STC.UNM ,  ST. JUDE CHILDREN'S RESEARCH HOSPITAL ,  THE CHILDREN'S HOSPITAL OF PHILADELPHIA on behalf of CHILDREN'S ONCOLOGY GROUP

Inventor： Cheryl L. Willman ,  Stephen P. Hunger ,  Charles Mullighan ,  I-Ming Chen ,  Kathryn G. Roberts ,  Huining Kang ,  Richard C. Harvey

IPC: C12Q1/6886

Abstract: The invention provides arrays, systems, devices, methods, computer-readable media and kits that enable expression-based classification of B-precursor acute lymphoblastic leukemia (ALL) as being either responsive or non-responsive to tyrosine kinase inhibitor mono or co-therapy.

公开(公告)号：US20200244038A1

公开(公告)日：2020-07-30

申请号：US16775200

申请日：2020-01-28

Applicant: STC.UNM

Inventor： Marek Osinski ,  Alexander Neumann ,  Gennady A. Smolyakov

IPC: H01S5/024 ,  H01S5/34 ,  H01S5/347 ,  H01S5/026

Abstract: A semiconductor device comprising a waveguide having a core, said core having inserted therein one or more layers of nanoemitters.

公开(公告)号：US20200170952A1

公开(公告)日：2020-06-04

申请号：US16618011

申请日：2018-05-31

Applicant: STC.UNM ,  Swinburne University of Technology

Inventor： Heather Canavan ,  Phuong Anh Nguyen ,  Sally McArthur ,  Darnell Leon Cuylear

IPC: A61K9/16 ,  A61K9/50 ,  A61K33/00 ,  A61K33/14

Abstract: A preparation comprised of one or more pellets having an outer shell and core. The outer shell is made of dissolvable material and said core containing poly (ethylene glycol).

公开(公告)号：US10671350B2

公开(公告)日：2020-06-02

申请号：US16051427

申请日：2018-07-31

Applicant: STC.UNM

Inventor： James Plusquellic

IPC: G06F7/58 ,  G09C1/00 ,  H04L9/00 ,  H04L9/08

Abstract: This disclosure describes techniques for analyzing statistical quality of bitstrings produced by a physical unclonable function (PUF). The PUF leverages resistance variations in the power grid wires of an integrated circuit. Temperature and voltage stability of the bitstrings are analyzed. The disclosure also describes converting a voltage drop into a digital code, wherein the conversion is resilient to simple and differential side-channel attacks.

公开(公告)号：US10666256B2

公开(公告)日：2020-05-26

申请号：US16185921

申请日：2018-11-09

Applicant: STC.UNM

Inventor： James Plusquellic ,  James Aarestad

IPC: H03K19/003 ,  H03K19/21 ,  H03K3/84 ,  H03K23/00 ,  H04L9/06 ,  H04L9/08

Abstract: A Hardware-Embedded Delay PUF (HELP) leverages entropy by monitoring path stability and measuring path delays from core logic macros. HELP incorporates techniques to deal with bias. A unique feature of HELP is that it may compare data measured from different test structures. HELP may be implemented in existing FPGA platforms. HELP may leverage both path stability and within-die variations as sources of entropy.

公开(公告)号：US20200158720A1

公开(公告)日：2020-05-21

申请号：US16707501

申请日：2019-12-09

Applicant: STC.UNM

Inventor： David G. Whitten ,  Harry Craig Pappas ,  Eric H. Hill ,  Yue Zhang ,  Eva Yung Hua Chi ,  Arjun Thapa ,  Ying Wang ,  Patrick L. Donabedian ,  Kiran Bhaskar

IPC: G01N33/52 ,  C12Q1/46 ,  C12Q1/44 ,  C12N1/20 ,  C08G61/02

Abstract: Various embodiments relate to p-phenylene ethynylene compounds as bioactive and detection agents. In various embodiments, the present invention provides a method of inducing germination of microbial spores including contacting the microbial spores with a p-phenylene ethynylene compound. In various embodiments, the present invention provides a method for detecting an enzyme, a method of protein analysis, or a method of detecting a chemical agent, including introducing a p-phenylene ethylylene compound to a composition including an enzyme substrate, and analyzing the fluorescence of the p-phenylene ethynylene compound. Various embodiments provide sensors that include a p-phenylene ethynylene compound and an enzyme substrate.