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公开(公告)号：US09567492B2
公开(公告)日：2017-02-14
申请号：US14471755
申请日：2014-08-28
Inventor： Rajiv K. Singh , Arul Chakkaravarthi Arjunan , Kannan Balasundaram , Deepika Singh , Wei Bai
CPC classification number: C09G1/04 , B24B37/044 , C09G1/02 , C09K3/1436 , C09K3/1463 , C30B33/00 , H01L21/02002 , H01L21/02024 , H01L21/30625
Abstract: A chemical mechanical polishing (CMP) includes providing a slurry including composite particles dispersed in a water-based carrier that comprise a plurality of hard particles on an outer surface of a soft-core particle. The hard particles have a Mohs hardness at least 1 greater than a Mohs hardness of the soft core particle and/or a Vickers hardness at least 500 Kg/mm2 greater than the soft-core particle. A substrate having a substrate surface with a hardness greater than a Mohs number of 6 or a Vickers hardness greater than 1,000 kg/mm2 is placed into a CMP apparatus having a rotating polishing pad, and CMP is performed with the rotating polishing pad and the slurry to polish the substrate surface.
Abstract translation: 化学机械抛光（CMP）包括提供包括分散在水性载体中的复合颗粒的浆料，其包含在软核颗粒的外表面上的多个硬颗粒。 硬质颗粒具有比软核颗粒的莫氏硬度至少大1的莫氏硬度和/或比软核颗粒大至少500kg / mm 2的维氏硬度。 将具有大于莫氏数6的维氏硬度大于1000kg / mm2的基板表面的基板放置在具有旋转抛光垫的CMP设备中，并且用旋转抛光垫和浆料进行CMP 抛光衬底表面。
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272.发明申请公开(公告)号：US20170032524A1
公开(公告)日：2017-02-02
申请号：US15302598
申请日：2015-04-10
Inventor： Daniel John Dickrell, III , David L. Meadows
IPC: G06T7/00
CPC classification number: G06T7/0014 , G06T7/11 , G06T11/001 , G06T2207/30016 , G06T2207/30041 , G06T2207/30048 , G06T2207/30061 , G06T2207/30068 , G06T2207/30084 , G06T2207/30101 , G06T2207/30104
Abstract: Disclosed herein is a method comprising a method comprising imaging a network section through which flow occurs; where the flow is selected from a group consisting of fluid, electrons, protons, neutrons and holes; partitioning the image into sub-regions based on metabolic need and function; where each region comprises one or more sources and one or more sinks; where the flow emanates from the source and exits into the sinks; generating a Voronoi diagram from the Delaunay triangulation by subdividing the sub-regions into Voronoi cells, where each Voronoi cell contains exactly one sink or one source; and where the intersections of Voronoi cells are Voronoi cell vertices; calculating a flow rate in each Voronoi cell; and according a color to Voronoi cells based on their flow rates; where Voronoi cells having similar rates are accorded similar colors.
Abstract translation: 本文公开了一种方法，包括一种方法，其包括对网络部分成像，通过该网络部分发生流动; 其中流动选自流体，电子，质子，中子和孔; 根据代谢需要和功能，将图像分割成亚区域; 其中每个区域包括一个或多个源和一个或多个汇点; 流量从源头流出并流入水槽; 通过将子区域细分为Voronoi单元，其中每个Voronoi单元包含正好一个汇或一个源，从Delaunay三角测量生成Voronoi图; 并且Voronoi细胞的交叉点是Voronoi细胞顶点; 计算每个Voronoi细胞中的流速; 并根据其流速根据Voronoi细胞的颜色; 其中具有相似速率的Voronoi细胞具有相似的颜色。
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273.发明授权Dual action lethal containers, systems, methods and compositions for killing adult mosquitos and larvae 有权用于杀死成年蚊子和幼虫的双作用致死容器，系统，方法和组合物公开(公告)号：US09554567B2
公开(公告)日：2017-01-31
申请号：US14881509
申请日：2015-10-13
Inventor： Philip G. Koehler , Ephraim V. Ragasa , Roberto M. Pereira
IPC: A01M1/20 , A01N37/38 , A01N43/40 , A01N57/16 , A01N63/00 , A01N47/22 , A01N49/00 , A01N53/00 , A01M1/04 , A01M1/10 , A01N43/22
CPC classification number: A01M1/2016 , A01M1/04 , A01M1/106 , A01M1/20 , A01M1/2005 , A01M1/2011 , A01N37/38 , A01N43/22 , A01N43/40 , A01N47/22 , A01N49/00 , A01N53/00 , A01N57/16 , A01N63/00 , Y02A50/356 , Y02A50/371 , A01N25/10 , A01N25/34 , A01N31/14 , A01N37/32 , A01N43/30
Abstract: Dual action lethal containers, systems, methods, compositions and formulas used to kill mosquitoes and their larvae. The containers can have separate interior larvicidal and adulticidal coatings separated from each other by horizontal water line holes in the container. Another container can use a novel combined coating of a larvicidal and adulticidal coating. Unique compositions of adulticidal coatings, larvicidal coatings and combined adulticidal and larvicidal coatings can be used as liners.
Abstract translation: 用于杀死蚊子及其幼虫的双作用致死容器，系统，方法，组合物和配方。 容器可以具有通过容器中的水平水线孔彼此分开的分开的内部杀幼体和杀虫涂层。 另一个容器可以使用杀虫剂和杀虫剂涂层的新颖组合涂层。 杀虫涂料，杀幼体涂料和联合杀虫剂和杀幼虫涂料的独特组合物可用作衬垫。
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公开(公告)号：US20170007720A1
公开(公告)日：2017-01-12
申请号：US15120425
申请日：2015-02-18
Inventor： Shannon E. Boye , Frank Dyka , Sanford L. Boye , William W. Hauswirth
CPC classification number: A61K48/0058 , A61K38/1709 , A61K45/06 , A61K48/0075 , A61K48/0083 , C12N7/00 , C12N15/86 , C12N2750/14122 , C12N2750/14123 , C12N2750/14143 , C12N2750/14145 , C12N2750/14171 , C12N2830/008
Abstract: Disclosed are capsid-modified rAAV expression vectors, as well as infectious virions, compositions, and pharmaceutical formulations that include them. Also disclosed are methods of preparing and using novel capsid-protein-mutated rAAV vector constructs in a variety of diagnostic and therapeutic applications including, inter alia, as delivery agents for diagnosis, treatment, or amelioration of one or more diseases, disorders, or dysfunctions of the mammalian eye. Also disclosed are methods for intravitreal delivery of therapeutic gene constructs to retinal neuron cells, and specifically to ON bipolar cells, of the mammalian eye, as well as use of the disclosed compositions in the manufacture of medicaments for a variety of in vitro and/or in vivo applications including the treatment of retinitis pigmentosa, melanoma-associated retinopathy, and congenital stationary night blindness.
Abstract translation: 公开了衣壳修饰的rAAV表达载体，以及感染性病毒粒子，组合物和包括它们的药物制剂。 还公开了在各种诊断和治疗应用中制备和使用新的衣壳蛋白突变的rAAV载体构建体的方法，包括特别地，作为用于诊断，治疗或改善一种或多种疾病，障碍或功能障碍的递送剂 的哺乳动物眼睛。 还公开了将治疗性基因构建体玻璃体内递送给视网膜神经元细胞，特别是哺乳动物眼睛的ON双极细胞的方法，以及所公开的组合物在制备多种体外和/或 体内应用，包括治疗色素性视网膜炎，黑素瘤相关性视网膜病变和先天性静止性夜盲。
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公开(公告)号：US09540254B2
公开(公告)日：2017-01-10
申请号：US13886321
申请日：2013-05-03
Inventor： Timothy Townsend , Ronald Bishop , David Wood , James Lloyd
IPC: C02F1/44 , B01D61/02 , C02F103/06
CPC classification number: C02F1/441 , B01D61/022 , B01D2317/025 , B01D2317/04 , C02F1/44 , C02F1/442 , C02F1/444 , C02F2103/06 , C02F2301/08 , C05C3/00
Abstract: Embodiments of the present disclosure provide for systems for removing contaminants from a leachate, methods of removing contaminants from a leachate, and the like.
Abstract translation: 本公开的实施例提供了用于从渗滤液中除去污染物的系统，从渗滤液中除去污染物等的方法。
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Patent Agency Ranking
公开(公告)号：US09536177B2
公开(公告)日：2017-01-03
申请号：US14557262
申请日：2014-12-01
Inventor： Rakesh Chalasani , Jose C. Principe
CPC classification number: G06K9/6249 , G06K9/3241 , G06K9/4628 , G06K9/6272 , G06N3/0445 , G06N3/0454
Abstract: Various examples are provided for object recognition in video. In one example, among others, a system includes processing circuitry including a processor. The processing circuitry is configured to process a sequence of images to recognize an object in the images, the recognition of the object based upon a hierarchical model. In another example, a method includes determining input data from a plurality of overlapping pixel patches of a video image; determining a plurality of corresponding states based at least in part upon the input data and an over-complete dictionary of filters; and determining a cause based at least in part upon the plurality of corresponding states. The cause may be used to identify an object in the video image.
Abstract translation: 为视频中的对象识别提供了各种示例。 在一个示例中，除其他之外，系统包括包括处理器的处理电路。 处理电路被配置为处理图像序列以识别图像中的对象，基于分层模型识别对象。 在另一示例中，一种方法包括从视频图像的多个重叠像素块中确定输入数据; 至少部分地基于所述输入数据和过滤器的过完整字典来确定多个对应状态; 以及至少部分地基于所述多个对应状态来确定原因。 原因可能用于识别视频图像中的对象。
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公开(公告)号：US20160372823A1
公开(公告)日：2016-12-22
申请号：US14902108
申请日：2014-07-03
Inventor： YONG-KYU YOON , CHEOLBOK KIM , JONG-KYU KIM
Abstract: Various examples are provided for spherical monopole antennas. In one example, among others, a spherical monopole antenna includes a spherical conductor on a first side of a substrate and a ground plane disposed on the substrate. The spherical conductor is electrically coupled to a connector via a tapered feeding line and the ground plane surrounds at least a portion of the connector on the second side of the substrate. In another example, among others, a method includes forming a tapered mold in a die layer disposed on a first side of a substrate, filling the tapered mold with a conductive paste, and disposing a spherical conductor on a large end of the tapered mold. The conductive paste is in contact with a signal line extending through the substrate into a small end of the tapered mold and in contact with the spherical conductor.
Abstract translation: 球形单极天线提供了各种实例。 在一个示例中，其中，球形单极天线包括在基板的第一侧上的球形导体和设置在基板上的接地平面。 球形导体经由锥形馈电线电连接到连接器，并且接地平面围绕衬底第二侧上的连接器的至少一部分。 在另一个实例中，其中包括在设置在基板的第一面上的模具层中形成锥形模具，用导电浆料填充锥形模具，并将球形导体设置在锥形模具的大端上。 导电膏与延伸穿过基板的信号线接触到锥形模的小端并与球形导体接触。
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公开(公告)号：US09511243B2
公开(公告)日：2016-12-06
申请号：US14394357
申请日：2013-04-12
Inventor： Guanghua Yan , Bo Lu , Chihray Liu , Jonathan G. Li
CPC classification number: A61N5/1048 , A61B6/03 , A61B6/583 , A61N5/1049 , A61N5/107 , A61N2005/1051 , A61N2005/1059 , A61N2005/1074 , G01B11/254 , G01S17/48 , G01S17/66 , G01S17/87 , H04N13/161
Abstract: A patient safety system (PSS) (100) uses optical tracking in a linear accelerator treatment room to prevent gross setup errors. A patient (150) undergoes a computed tomography (CT) treatment-simulation scan while a CT ball bearing (BB) is on patient's surface. The CT BB is replaced with an infrared reflective marker (IRRM) (160) before radiotherapy treatment starts. Coordinates of the CT BB relative to an isocenter of the treatment room are used as reference for tracking. The coordinate system of an optical tracking system is converted to a coordinate system of the treatment room. The PSS evaluates setup accuracy for a radiotherapy session by comparing real-time position of the single IRRM determined by the optical tracking technology with a predicted reference position, and displays results on a graphical user interface. The PSS stops radiation when a deviation between real-time coordinates and predicted coordinates of the IRRM (160) exceeds a predefined threshold.
Abstract translation: 患者安全系统（PSS）（100）在直线加速器治疗室中使用光学跟踪来防止总设置错误。 患者（150）经历计算机断层扫描（CT）治疗 - 模拟扫描，而CT球轴承（BB）在病人的表面上。 放射治疗开始之前，CT BB被替换为红外反射标记（IRRM）（160）。 CT BB相对于治疗室等角点的坐标被用作跟踪的参考。 光学跟踪系统的坐标系被转换为治疗室的坐标系。 PSS通过将由光学跟踪技术确定的单个IRRM的实时位置与预测的参考位置进行比较来评估放射治疗会话的设置精度，并在图形用户界面上显示结果。 当IRRM（160）的实时坐标和预测坐标之间的偏差超过预定阈值时，PSS停止辐射。
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公开(公告)号：US20160345941A1
公开(公告)日：2016-12-01
申请号：US15236552
申请日：2016-08-15
Inventor： Kyle Douglas Allen , Jon Paul Dobson , Elena Georgina Yarmola , Zachary Kaufman , David P. Arnold
IPC: A61B10/02 , G01N33/543 , G01N33/68 , A61B17/52 , A61B17/34
Abstract: Provided herein is a magnetic apparatus for collecting superparamagnetic particles from a subject. The superparamagnetic particles are previously injected into the subject and have ligands bound thereto that are specific for one or more non-cell biomarkers. In one embodiment, the superparamagnetic particles are injected into and retrieved from a cavity such as a joint cavity. These compositions and methods allow for the sequestration and removal of inflammatory mediators, as both a diagnostic of the local immune response and a therapeutic that can reduce inflammation in the local disease environment.
Abstract translation: 本文提供了一种用于从受试者收集超顺磁性颗粒的磁性装置。 超顺磁性颗粒预先注射到受试者中并且具有与一种或多种非细胞生物标志物特异性结合的配体。 在一个实施例中，超顺磁性颗粒被注入并从诸如关节腔的空腔中取出。 这些组合物和方法允许螯合和除去炎症介质，既是局部免疫应答的诊断，也是可以减少局部疾病环境中的炎症的治疗剂。
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280.发明申请CAPSID-MODIFIED, RAAV3 VECTOR COMPOSITIONS AND USES IN GENE THERAPY OF HUMAN LIVER CANCER 审中-公开CAPSID改性，RAAV3载体组合物和人类肝癌基因治疗中的用途公开(公告)号：US20160333372A1
公开(公告)日：2016-11-17
申请号：US14891241
申请日：2014-05-21
Inventor： Arun Srivastava , Li Zhong , Sergei Zolotukhin , George Vladimirovich Aslanidi , Mavis Agbandje-McKenna , Kim M. Van Vliet
IPC: C12N15/86
Abstract: Disclosed are next-generation multi-mutated capsid protein-modified rAAV expression vectors, as well as infectious virions, compositions, and pharmaceutical formulations that include them. Also disclosed are methods of preparing and using these high transduction efficiency vector constructs in a variety of therapeutic applications including, inter alia, as delivery agents for the treatment or amelioration of one or more diseases or abnormal conditions in an affected mammal using in vivo and/or ex situ viral vector-based gene therapy protocols. Also disclosed are large-scale production methods for the multi-mutated, capsid-modified rAAV expression vectors, viral particles, and infectious virions, as well as use of the disclosed compositions in the manufacture of medicaments for use in a variety of in vitro and/or in vivo therapeutic methodologies.
Abstract translation: 公开了下一代多突变衣壳蛋白修饰的rAAV表达载体，以及包含它们的感染性病毒粒子，组合物和药物制剂。 还公开了在各种治疗应用中制备和使用这些高转导效率载体构建体的方法，包括特别地，作为在受影响的哺乳动物中使用体内和/或体内治疗或改善一种或多种疾病或异常状况的递送剂，和/ 或基于病毒载体的基因治疗方案。 还公开了用于多突变的衣壳修饰的rAAV表达载体，病毒颗粒和感染性病毒粒子的大规模生产方法，以及所公开的组合物在制备用于各种体外和 /或体内治疗方法。
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