Abstract:
The invention relates to new PI3K/AKT/m TOR inhibitors and their use for the prevention and/or the treatment of a disease selected from the group consisting of: inflammatory diseases, autoimmune diseases, neurodegenerative diseases, cancers, transplant rejection, diseases characterized by a premature aging and tuberous sclerosis.
Abstract:
The invention relates to a multi port router device capable of carrying a number P, which is greater than or equal to three, of frequency channels, from a number M of input ports to a number N of output ports, at least one of the two numbers M and N being greater than or equal to two, characterized in that it includes at least two filters (12, 14, 16, 18), each filter comprising at least two coupled resonators, at least one resonator (Rs1, Rs2) being common to two different filters, and each input port and each output port being connected directly to at least one resonator. The router device is capable of appropriately performing routing in which it is possible to supply on at least one output port an output multiplex having at least a first and a second frequency channel, among which: the first frequency channel has originated from a first input multiplex, supplied on a first input port and comprising said first frequency channel, and at least one further frequency channel forwarded to a second output port of the device; and the second frequency channel is either forwarded from a second input port, or, when the first input multiplex comprises at least three different multiplexed frequency channels, the second frequency channel originates from the first input multiplex, the first second frequency channels, being frequentially disposed on both sides of a third frequency channel, with the said third frequency channel being routed to a different output port.
Abstract:
Method for shooting and editing a film comprising at least one image of a 3D computer-generated animation created by a cinematographic software according to mathematical model of elements that are part of the animation and according to a definition of situations and actions occurring for said elements as a function of time, said method being characterized by comprising the following: computing of alternative suggested viewpoints by the cinematographic software for an image of the 3D computer-generated animation corresponding to a particular time point according to said definition; and instructing for displaying on a display interface, all together, images corresponding to said computed alternative suggested viewpoints of the 3D computer-generated animation at that particular time point.
Abstract:
An electrical device includes a first electrical component and a second electrical component connected to each other via an electrical connection having an electrically insulating support plate and a weld joint deposited on the support plate. The weld joint has a melting temperature (Ta) significantly lower than an ambient operating temperature (Ta) to which at least one of the two electrical components and the electrical connection are subjected. The electrical device includes cement that completely covers the exposed weld joint. The material of the cement is chosen to maintain its adhesion and its tightness with respect to the weld joint when the Ta is applied.
Abstract:
The invention concerns a new family of discriminating molecules for neutron rays and gamma rays, and method for preparing the same. These molecules are also useful to detect radiation (X, gamma, electrons, protons, ions), and hence for the manufacture of instruments for radiation detection, industrial or medical dosimetry.
Abstract:
The invention relates to lipochitooligosaccharides obtainable from arbuscular mycorrhizal fungi, and which are useful for stimulating arbuscular mycorrhizal symbiosis, and lateral root formation.
Abstract:
A method for preparing a composition includes silico/germano-metal particles functionalized by at least one organic group, which involves:—carrying out a hydrothermal treatment of a hydrogel precursor of the silico/germano-metal mineral particles, and—preparing a hydrogel including silico/germano-metal particles having at least one organic group by co-precipitation in an aqueous medium. A composition including functionalized silico/germano-metal mineral particles of which 1% to 75% of the silicon atoms and/or of the germanium atoms are covalently bonded to at least one organic group is also described.
Abstract:
Long-chain alkyl cyclic acetals made from sugars are obtainable by a method that comprises the steps consisting of: dehydrating a hexitol in a monoanhydrohexitol substrate; reacting the monoanhydrohexitol substrate obtained with an alkyl aldehyde reagent containing 5 to 18 carbon atoms, by means of an acetalization reaction with a substrate/reagent ratio of between 5:1 and 1:1, or with a derivative of an alkyl aldehyde reagent containing 5 to 18 carbon atoms, by means of a transacetalization reaction with a substrate/reagent ratio of between 1:1 and 1:3, in the presence of acid catalyst and in an environment that is free of solvent or that consists of non-aqueous polar solvent; collecting the long-chain alkyl acetal of hexitan from the mixture obtained.
Abstract:
The present invention relates to a composition, comprising: at least one non-crosslinked silicone, and at least one antimicrobial agent dispersed within said silicone, said antimicrobial agent being selected from the group consisting of polymers of ionenes, and of ionic liquids with a molecular mass of less than 1,400 g/mol.
Abstract:
The invention relates to a device (10) including a plurality of thin layers (12, 14, 18) comprising a layer (14) formed with a polarizable ferroelectric material according to several polarization directions depending on an electric voltage applied to said layer of ferroelectric material, surrounded by a pair of conductive layers (12, 18) forming electrodes. The device of the invention comprises an intermediate layer (16) between said ferroelectric material layer (14) and one of the conductive layers (12, 18), said intermediate layer (16) consisting of a material for which the electronic properties are modified according to the direction of polarization in said adjacent ferroelectric material layout (14). The device for the invention finds particularly advantageous applications as a memory element of a non-volatile memory, as an element of a programmable logic circuit and as a microswitch.