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    CONJUGATED POLYMERS FOR USE IN HOMOGENEOUS AND SOLID STATE ASSAYS
    21.
    发明申请
    CONJUGATED POLYMERS FOR USE IN HOMOGENEOUS AND SOLID STATE ASSAYS 有权
    共聚聚合物用于均质和固体状态测定

    公开(公告)号：US20120035066A1

    公开(公告)日：2012-02-09

    申请号：US13038378

    申请日：2011-03-01

    Applicant: Guillermo C. Bazan ,  Bin Liu

    Inventor： Guillermo C. Bazan ,  Bin Liu

    IPC: C40B30/04 ,  G01N21/64 ,  C08G75/32 ,  G01N33/53

    CPC classification number: C08G61/02 ,  C08G61/122 ,  C08G61/123 ,  C12Q1/6818 ,  C12Q1/6837 ,  G01N21/6428 ,  G01N21/6452 ,  G01N2021/6419 ,  G01N2021/6439 ,  C12Q2563/131 ,  C12Q2537/119 ,  C12Q2525/107

    Abstract: The invention further relates to multichromophores, which may be conjugated polymers, and methods, articles and compositions employing them as described herein. In some aspects, the invention relates to methods, articles and compositions for the detection and analysis of biomolecules in a sample. Provided assays include those determining the presence of a target biomolecule in a sample or its relative amount, or the assays may be quantitative or semi-quantitative. The methods can be performed on a substrate. The methods can be performed in an array format on a substrate, which can be a sensor. In some embodiments, detection assays are provided employing sensor biomolecules that do not comprise a fluorophore that can exchange energy with the cationic multichromophore. In some aspects biological assays are provided in which energy is transferred between one or more of the multichromophore, a label on the target biomolecule, a label on the sensor biomolecule, and/or a fluorescent dye specific for a polynucleotide, in all permutations. The multichromophore may interact at least in part electrostatically with the sensor and/or the target, and an increase in energy transfer with the polymer may occur upon binding of the sensor and the target. Other variations of the inventions are described further herein.

    Abstract translation: 本发明还涉及可以是共轭聚合物的多色素，以及如本文所述使用它们的方法，制品和组合物。 在一些方面，本发明涉及用于检测和分析样品中生物分子的方法，制品和组合物。 提供的测定包括确定样品中靶生物分子的存在或其相对量的那些，或者测定可以是定量或半定量的。 该方法可以在衬底上进行。 这些方法可以以阵列格式在基底上进行，其可以是传感器。 在一些实施方案中，使用不包含能够与阳离子多重色素交换能量的荧光团的传感器生物分子来提供检测测定。 在一些方面，提供生物测定，其中在所有置换中，能量在一个或多个多色素，目标生物分子上的标记，传感器生物分子上的标记和/或多核苷酸特异的荧光染料之间转移。 多重色淀可以至少部分地与传感器和/或靶相互作用，并且当传感器和目标物结合时，聚合物的能量传递的增加可能发生。 本文进一步描述了本发明的其它变型。

    GROWTH METHOD OF FE3N MATERIAL
    22.
    发明申请
    GROWTH METHOD OF FE3N MATERIAL 有权
    FE3N材料的生长方法

    公开(公告)号：US20110269250A1

    公开(公告)日：2011-11-03

    申请号：US12772508

    申请日：2010-05-03

    Applicant: Rong Zhang ,  Zili Xie ,  Bin Liu ,  Xiangqian Xiu ,  Henan Fang ,  Hong Zhao ,  Xuemei Hua ,  Ping Han ,  Peng Chen ,  Youdou Zheng

    Inventor： Rong Zhang ,  Zili Xie ,  Bin Liu ,  Xiangqian Xiu ,  Henan Fang ,  Hong Zhao ,  Xuemei Hua ,  Ping Han ,  Peng Chen ,  Youdou Zheng

    IPC: H01L21/3205

    CPC classification number: C23C16/0272 ,  C23C16/34 ,  C30B25/02 ,  C30B29/38 ,  H01L21/0242 ,  H01L21/02458 ,  H01L21/02502 ,  H01L21/0262

    Abstract: A kind of growth method of Fe3N, and the growth is in the MOCVD system, including following process: 1). the surface nitridation of sapphire substrate would be made; 2). pump in carrier gas N2, ammonia and organic gallium sources, and grow low temperature GaN buffer on substrate; 3). the temperature would be raised and grow the GaN supporting layer; 4). pump in FeCp2 as Fe sources, then grow Fe3N on the GaN supporting layer; the Fe3N granular films and the Fe3N single crystal films could be obtained. The invention realizes growing high quality Fe3N film. According to the problem of growing material with difficulty, the problems are solved by controlling and adjusting the conditions for the flux of organic gallium source and iron source, growth temperature, growth time, the flux of ammonia, and mole ratio of N and Ga. In the invention, the method is easy, the growth process could be controlled, and thus the growth method and the process control of growth technology have advancement.

    Abstract translation: 一种Fe3N的生长方法，并且生长在MOCVD系统中，包括以下过程：1）。 将制作蓝宝石衬底的表面氮化; 2）。 泵送载气N2，氨和有机镓源，并在底物上生长低温GaN缓冲液; 3）。 温度升高并生长GaN支撑层; 4）。 泵浦FeCp2作为Fe源，然后在GaN支撑层上生长Fe3N; 可以获得Fe3N颗粒膜和Fe3N单晶膜。 本发明实现了生长高品质的Fe3N膜。 根据难以生长材料的问题，通过控制和调节有机镓源和铁源的通量条件，生长温度，生长时间，氨通量和N和Ga的摩尔比来解决问题。 在本发明中，该方法容易，可以控制生长过程，因此生长方法和生长技术的过程控制有所进步。

    STRUCTURES INCORPORATING CONFORMATIONALLY FLEXIBLE CONJUGATED POLYMERS AND METHODS OF USE
    23.
    发明申请
    STRUCTURES INCORPORATING CONFORMATIONALLY FLEXIBLE CONJUGATED POLYMERS AND METHODS OF USE 有权
    具有连续柔性结合聚合物的结构和使用方法

    公开(公告)号：US20110183439A1

    公开(公告)日：2011-07-28

    申请号：US13075172

    申请日：2011-03-29

    Applicant: Guillermo C. Bazan ,  Bin Liu

    Inventor： Guillermo C. Bazan ,  Bin Liu

    IPC: G01N33/543 ,  C08F283/00

    CPC classification number: H01B1/122 ,  C08G61/02 ,  C08G61/10 ,  C08G61/123 ,  C08G61/126 ,  C08G73/02 ,  C08G73/08 ,  C40B40/04

    Abstract: Methods, compositions and articles of manufacture involving conformationally flexible conjugated polymers are provided. A structure is provided comprising the conformationally flexible conjugated polymer bound to or associated with at least one member of a binding pair comprising a sensor molecule and a target molecule or the complex they form. The conformationally flexible conjugated polymer comprises at least one angled linker having bonds to its two adjacent polymeric units which form an angle of less than about 155° with respect to one another. Methods of use of such structures and solutions comprising them are also provided.

    Abstract translation: 提供涉及构象柔性共轭聚合物的方法，组合物和制品。 提供了包含结构柔性共轭聚合物结构或与至少一个包含传感器分子和靶分子或其形成的复合物的结合对成员相关联的结构。 构象柔性的共轭聚合物包括至少一个成角度的连接体，其具有与其两个相邻的聚合物单元的键合，其相对于彼此形成小于约155°的角度。 还提供了使用这种结构的方法和包括它们的溶液。

    Conformationally flexible cationic conjugated polymers
    25.
    发明授权
    Conformationally flexible cationic conjugated polymers 有权
    构象柔性阳离子共轭聚合物

    公开(公告)号：US07914984B2

    公开(公告)日：2011-03-29

    申请号：US11561893

    申请日：2006-11-21

    Applicant: Guillermo C Bazan ,  Bin Liu

    Inventor： Guillermo C Bazan ,  Bin Liu

    IPC: C08F297/02

    CPC classification number: H01B1/122 ,  C08G61/02 ,  C08G61/10 ,  C08G61/123 ,  C08G61/126 ,  C08G73/02 ,  C08G73/08 ,  C40B40/04

    Abstract: Methods, compositions and articles of manufacture involving cationic conjugated conformationally flexible polymers are provided. A method for the synthesis of cationic water-soluble polymers with linkages along the polymer main chain structure which disrupt the ability of the polymers to form extended-rod structures is provided. Such polymers may serve in the fabrication of novel optoelectronic devices and in the development of highly efficient biosensors. The invention further relates to the application of these polymers in assay methods.

    Abstract translation: 提供涉及阳离子共轭构象柔性聚合物的方法，组合物和制品。 提供了一种用于合成阳离子水溶性聚合物的方法，所述聚合物具有沿聚合物主链结构的连接，其破坏聚合物形成延伸棒结构的能力。 这种聚合物可用于制造新的光电器件和开发高效生物传感器。 本发明还涉及这些聚合物在测定方法中的应用。

    Shock-absorbing wheel mounting structure for jack
    28.
    发明授权
    Shock-absorbing wheel mounting structure for jack 失效
    千斤顶减震轮安装结构

    公开(公告)号：US07845614B2

    公开(公告)日：2010-12-07

    申请号：US11735246

    申请日：2007-04-13

    Applicant: Bin Liu

    Inventor： Bin Liu

    IPC: B66F3/00

    CPC classification number: B66F5/00 ,  B60B33/0002 ,  B60B33/001 ,  B60B33/0021 ,  B60B33/0039 ,  B60B33/0049 ,  B60B33/0057 ,  B60B33/0068 ,  B60B33/0073 ,  B60B33/045 ,  B60G3/01 ,  B60G11/16 ,  B66F13/00 ,  F16F1/127

    Abstract: A shock-absorbing wheel mounting structure used in a horizontal jack is disclosed. The wheel mounting structure includes an axial sleeve (4) affixed to a rear wheel mount (5) of the horizontal jack (100), and a shaft (2), vertically slideably mounted in the axial sleeve (4) and riveted to a bracket (1). The bracket (1) supports a wheel (71). A compression spring (3) is sleeved onto the shaft (2) and stopped between a stop flange around the periphery of the shaft (2) and the top wall of the axial sleeve (4). This arrangement serves to impart a downward pressure to the shaft (2) relative to the axial sleeve (4).

    Abstract translation: 公开了一种在水平千斤顶中使用的减震轮安装结构。 车轮安装结构包括固定到水平千斤顶（100）的后轮安装件（5）上的轴向套筒（4）和可垂直地可滑动地安装在轴向套筒（4）中并铆接到支架 （1）。 支架（1）支撑轮（71）。 压缩弹簧（3）套在轴（2）上并且停在围绕轴（2）的周边的止动凸缘和轴向套筒（4）的顶壁之间。 这种布置用于相对于轴向套筒（4）向轴（2）施加向下的压力。

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