公开(公告)号：US20160198988A1

公开(公告)日：2016-07-14

申请号：US15060401

申请日：2016-03-03

申请人： DexCom, Inc.

发明人： Naresh C. Bhavaraju ,  Michael A. Bloom ,  Leif N. Bowman ,  Alexandra Lynn Carlton ,  Katherine Yerre Koehler ,  Hari Hampapuram ,  Jonathan Hughes ,  Lauren Hruby Jepson ,  Apurv Ulas Kamath ,  Anna Leigh Rack-Gomer ,  Peter C. Simpson ,  Stephen J. Vanslyke

IPC分类号： A61B5/145 ,  A61B5/1495 ,  A61B5/00

CPC分类号： A61B5/14532 ,  A61B5/0002 ,  A61B5/0004 ,  A61B5/14503 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/1486 ,  A61B5/1495 ,  A61B5/6898 ,  A61B5/72 ,  A61B5/7221 ,  A61B5/7275 ,  A61B5/7282 ,  A61B5/742 ,  A61B5/7435 ,  A61B5/746 ,  A61B5/7475 ,  A61B2560/0223 ,  A61B2560/0487 ,  A61M5/1723 ,  A61M2230/005 ,  A61M2230/201 ,  G16H40/40 ,  G16H40/63 ,  Y02A90/26

摘要： Systems and methods described provide dynamic and intelligent ways to change the required level of user interaction during use of a monitoring device. The systems and methods generally relate to real time switching between a first or initial mode of user interaction and a second or new mode of user interaction. In some cases, the switching will be automatic and transparent to the user, and in other cases user notification may occur. The mode switching generally affects the user's interaction with the device, and not just internal processing. The mode switching may relate to calibration modes, data transmission modes, control modes, or the like.

公开(公告)号：US20160183855A1

公开(公告)日：2016-06-30

申请号：US15065589

申请日：2016-03-09

申请人： DexCom, Inc.

发明人： Stephen J. Vanslyke ,  Naresh C. Bhavaraju ,  Lucas Bohnett ,  Arturo Garcia ,  Apurv Ullas Kamath ,  Jack Pryor

IPC分类号： A61B5/1495 ,  G06F19/00

摘要： Systems and methods for processing sensor data and calibration of the sensors are provided. In some embodiments, the method for calibrating at least one sensor data point from an analyte sensor comprises receiving a priori calibration distribution information; receiving one or more real-time inputs that may influence calibration of the analyte sensor; forming a posteriori calibration distribution information based on the one or more real-time inputs; and converting, in real-time, at least one sensor data point calibrated sensor data based on the a posteriori calibration distribution information.

摘要翻译： 提供了用于处理传感器数据和传感器校准的系统和方法。 在一些实施例中，用于从分析物传感器校准至少一个传感器数据点的方法包括接收先验校准分布信息; 接收可影响分析物传感器校准的一个或多个实时输入; 基于所述一个或多个实时输入形成后验校准分布信息; 并且基于后验校准分布信息实时地转换至少一个传感器数据点校准的传感器数据。

公开(公告)号：US20150119668A1

公开(公告)日：2015-04-30

申请号：US14526254

申请日：2014-10-28

申请人： DexCom, Inc.

发明人： Phil Mayou ,  Naresh C. Bhavaraju ,  Leif N. Bowman ,  Alexandra Lynn Carlton ,  Laura J. Dunn ,  Katherine Yerre Grubstein ,  Aarthi Mahalingam ,  Eli Reihman ,  Peter C. Simpson

IPC分类号： G06F19/00 ,  A61B5/145

CPC分类号： G09B5/02 ,  A61B5/01 ,  A61B5/1112 ,  A61B5/1118 ,  A61B5/14532 ,  A61B5/14552 ,  A61B5/165 ,  A61B5/7275 ,  A61B5/7282 ,  A61B5/742 ,  A61B5/746 ,  G06F19/00 ,  G06F19/3418 ,  G09B19/00 ,  G16H15/00 ,  G16H40/63 ,  G16H40/67 ,  H04L67/12

摘要： Systems and methods that continuously adapt aspects of a continuous monitoring device based on collected information to provide an individually tailored configuration are described. The adaptations may include adapting the user interface, the alerting, the motivational messages, the training, and the like. Such adaptation can allow a patient to more readily identify and understand the information provided by/via the device.

公开(公告)号：US20150046124A1

公开(公告)日：2015-02-12

申请号：US14523247

申请日：2014-10-24

申请人： DexCom, Inc.

发明人： Naresh C. Bhavaraju ,  Arturo Garcia ,  Hari Hampapuram ,  Apurv Ullas Kamath ,  Aarthi Mahalingam ,  Dmytro Sokolovskyy ,  Stephen J. Vanslyke

IPC分类号： G01N33/66 ,  G01N33/487 ,  G01N33/49

CPC分类号： G01N33/48792 ,  A61B5/14532 ,  A61B5/1495 ,  A61B5/7221 ,  A61B2560/0223 ,  A61B2560/0266 ,  A61B2560/0276 ,  A61B2560/028 ,  G01M99/008 ,  G01N33/49 ,  G01N33/66 ,  G06F19/70 ,  G06F19/708

摘要： Systems and methods for processing sensor data and end of life detection are provided. In some embodiments, a method for determining the end of life of a continuous analyte sensor includes evaluating a plurality of risk factors using an end of life function to determine an end of life status of the sensor and providing an output related to the end of life status of the sensor. The plurality of risk factors may be selected from the list including the number of days the sensor has been in use, whether there has been a decrease in signal sensitivity, whether there is a predetermined noise pattern, whether there is a predetermined oxygen concentration pattern, and error between reference BG values and EGV sensor values.

摘要翻译： 提供了用于处理传感器数据和寿命终止检测的系统和方法。 在一些实施例中，用于确定连续分析物传感器的寿命终止的方法包括使用寿命终止功能评估多个危险因素以确定传感器的寿命状态并提供与寿命结束相关的输出 传感器的状态 可以从包括传感器已经使用的天数的列表中选择多个危险因素，信号灵敏度是否下降，是否存在预定的噪声模式，是否存在预定的氧浓度模式， 参考BG值和EGV传感器值之间的误差。

公开(公告)号：US20140278189A1

公开(公告)日：2014-09-18

申请号：US13827119

申请日：2013-03-14

申请人： DEXCOM, INC.

发明人： Stephen J. Vanslyke ,  Naresh C. Bhavaraju ,  Lucas Bohnett ,  Arturo Garcia ,  Apurv Ullas Kamath ,  Jack Pryor

IPC分类号： A61B5/1495

CPC分类号： A61B5/1495 ,  G16H40/40

摘要： Systems and methods for processing sensor data and calibration of the sensors are provided. In some embodiments, the method for calibrating at least one sensor data point from an analyte sensor comprises receiving a priori calibration distribution information; receiving one or more real-time inputs that may influence calibration of the analyte sensor; forming a posteriori calibration distribution information based on the one or more real-time inputs; and converting, in real-time, at least one sensor data point calibrated sensor data based on the a posteriori calibration distribution information.

摘要翻译： 提供了用于处理传感器数据和传感器校准的系统和方法。 在一些实施例中，用于从分析物传感器校准至少一个传感器数据点的方法包括接收先验校准分布信息; 接收可影响分析物传感器校准的一个或多个实时输入; 基于所述一个或多个实时输入形成后验校准分布信息; 并且基于后验校准分布信息实时地转换至少一个传感器数据点校准的传感器数据。

公开(公告)号：US12048540B2

公开(公告)日：2024-07-30

申请号：US16261339

申请日：2019-01-29

申请人： DexCom, Inc.

发明人： Stephen J. Vanslyke ,  Naresh C. Bhavaraju ,  Sebastian Böhm ,  Leif N. Bowman ,  Michael J. Estes ,  Arturo Garcia ,  Apurv Ullas Kamath ,  Andrew Attila Pal ,  Thomas A. Peyser ,  Anna Leigh Davis ,  Daiting Rong ,  Disha B. Sheth ,  Peter C. Simpson ,  Dmytro Sokolovsky

IPC分类号： A61B5/1495 ,  A61B5/00 ,  A61B5/01 ,  A61B5/053 ,  A61B5/11 ,  A61B5/145 ,  A61B5/1473 ,  A61B5/1486 ,  A61M5/172 ,  G16Z99/00

CPC分类号： A61B5/1495 ,  A61B5/01 ,  A61B5/053 ,  A61B5/1118 ,  A61B5/14532 ,  A61B5/14542 ,  A61B5/14546 ,  A61B5/1473 ,  A61B5/14865 ,  A61B5/4833 ,  A61B5/4839 ,  A61B5/4848 ,  A61B5/4866 ,  A61B5/6898 ,  A61B5/7203 ,  A61B5/7221 ,  A61B5/7275 ,  A61B5/7278 ,  A61B5/7282 ,  A61B5/742 ,  A61B5/746 ,  A61M5/1723 ,  G16Z99/00 ,  A61B2560/0247 ,  A61B2560/0252 ,  A61B2560/0276 ,  A61B2560/0475 ,  A61B2562/0247 ,  A61M2205/3584 ,  A61M2205/3592 ,  A61M2205/50 ,  A61M2205/52 ,  A61M2230/201

摘要： Systems and methods disclosed here provide ways to discriminate fault types encountered in analyte sensors and systems and further provide ways to process such discriminated faults responsively based on sensor data, clinical context information, and other data about the patient or patient's environment. The systems and methods thus employ clinical context in detecting and/or responding to errors or faults associated with an analyte sensor system, and discriminating the type of fault, and its root cause, particularly as fault dynamics can appear similar to the dynamics of physiological systems, emphasizing the importance of discriminating the fault and providing appropriate responsive processing. Thus, the disclosed systems and methods consider the context of the patient's health condition or state in determining how to respond to the fault.

公开(公告)号：US11974845B2

公开(公告)日：2024-05-07

申请号：US17368541

申请日：2021-07-06

申请人： DexCom, Inc.

发明人： Rui Ma ,  Naresh C. Bhavaraju ,  Thomas Stuart Hamilton ,  Jonathan Hughes ,  Jeff Jackson ,  David I-Chun Lee ,  Peter C. Simpson ,  Stephen J. Vanslyke

IPC分类号： A61B5/1495 ,  A61B5/145 ,  G01N33/66 ,  A61B5/1486

CPC分类号： A61B5/1495 ,  A61B5/14532 ,  G01N33/66 ,  A61B5/14865

摘要： Systems and methods are disclosed which provide for a “factory-calibrated” sensor. In doing so, the systems and methods include predictive prospective modeling of sensor behavior, and also include predictive modeling of physiology. With these two correction factors, a consistent determination of sensitivity can be achieved, thus achieving factory calibration.

公开(公告)号：US11837348B2

公开(公告)日：2023-12-05

申请号：US17933197

申请日：2022-09-19

申请人： Dexcom, Inc.

发明人： Anna Leigh Davis ,  Scott M. Belliveau ,  Naresh C. Bhavaraju ,  Leif N. Bowman ,  Rita M. Castillo ,  Alexandra Elena Constantin ,  Rian W. Draeger ,  Laura J. Dunn ,  Gary Brian Gable ,  Arturo Garcia ,  Thomas Hall ,  Hari Hampapuram ,  Christopher Robert Hannemann ,  Anna Claire Harley-Trochimczyk ,  Nathaniel David Heintzman ,  Andrea Jean Jackson ,  Lauren Hruby Jepson ,  Apurv Ullas Kamath ,  Katherine Yerre Koehler ,  Aditya Sagar Mandapaka ,  Samuel Jere Marsh ,  Gary A. Morris ,  Subrai Girish Pai ,  Andrew Attila Pal ,  Nicholas Polytaridis ,  Philip Thomas Pupa ,  Eli Reihman ,  Ashley Anne Rindfleisch ,  Sofie Wells Schunk ,  Peter C. Simpson ,  Daniel S. Smith ,  Stephen J. Vanslyke ,  Matthew T. Vogel ,  Tomas C. Walker ,  Benjamin Elrod West ,  Atiim Joseph Wiley

IPC分类号： G16H20/17 ,  G16H50/20 ,  G06N20/00 ,  A61B5/00 ,  H04M1/72412 ,  A61B5/024 ,  A61B5/11 ,  A61B5/145 ,  A61B5/16 ,  G08B21/04 ,  G06N5/043 ,  A61M5/172 ,  G16H40/67 ,  G16H40/63

CPC分类号： G16H20/17 ,  A61B5/0022 ,  A61B5/024 ,  A61B5/1112 ,  A61B5/14517 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/165 ,  A61B5/4866 ,  A61B5/742 ,  A61B5/746 ,  A61M5/1723 ,  G06N5/043 ,  G06N20/00 ,  G08B21/0453 ,  G16H40/63 ,  G16H40/67 ,  G16H50/20 ,  H04M1/72412 ,  A61M2205/18 ,  A61M2205/3584 ,  A61M2205/50 ,  A61M2205/502 ,  A61M2205/52 ,  A61M2205/581 ,  A61M2205/582 ,  A61M2205/8206 ,  A61M2230/201 ,  Y02A90/10

摘要： Systems and methods are disclosed that provide smart alerts to users, e.g., alerts to users about diabetic states that are only provided when it makes sense to do so, e.g., when the system can predict or estimate that the user is not already cognitively aware of their current condition, e.g., particularly where the current condition is a diabetic state warranting attention. In this way, the alert or alarm is personalized and made particularly effective for that user. Such systems and methods still alert the user when action is necessary, e.g., a bolus or temporary basal rate change, or provide a response to a missed bolus or a need for correction, but do not alert when action is unnecessary, e.g., if the user is already estimated or predicted to be cognitively aware of the diabetic state warranting attention, or if corrective action was already taken.

公开(公告)号：US11690577B2

公开(公告)日：2023-07-04

申请号：US16884593

申请日：2020-05-27

申请人： DexCom, Inc.

发明人： Hari Hampapuram ,  Anna Leigh Davis ,  Naresh C. Bhavaraju ,  Apurv Ullas Kamath ,  Claudio Cobelli ,  Giovanni Sparacino ,  Andrea Facchinetti ,  Chiara Zecchin

IPC分类号： A61B5/00 ,  A61B5/145

CPC分类号： A61B5/746 ,  A61B5/0004 ,  A61B5/0022 ,  A61B5/0031 ,  A61B5/14503 ,  A61B5/14532 ,  A61B5/4848 ,  A61B5/4866 ,  A61B5/7221 ,  A61B5/7275 ,  A61B5/002

摘要： Systems and methods for providing sensitive and specific alarms indicative of glycemic condition are provided herein. In an embodiment, a method of processing sensor data by a continuous analyte sensor includes: evaluating sensor data using a first function to determine whether a real time glucose value meets a first threshold; evaluating sensor data using a second function to determine whether a predicted glucose value meets a second threshold; activating a hypoglycemic indicator if either the first threshold is met or if the second threshold is predicted to be met; and providing an output based on the activated hypoglycemic indicator.

公开(公告)号：US20230140651A1

公开(公告)日：2023-05-04

申请号：US18049924

申请日：2022-10-26

申请人： Dexcom. Inc.

发明人： Arturo Garcia ,  Peter C. Simpson ,  Apurv U. Kamath ,  Naresh C. Bhavaraju ,  Stephen J. Vanslyke

IPC分类号： A61B5/00 ,  A61B5/145 ,  A61B5/1495

摘要： Systems and methods are provided to calibrate an analyte concentration sensor within a biological system, generally using only a signal from the analyte concentration sensor. For example, at a steady state, the analyte concentration value within the biological system is known, and the same may provide a source for calibration. Similar techniques may be employed with slow-moving averages. Variations are disclosed.