Aromatic benzopyranyl and benzopyranyl compounds; their preparation; and
their use in cosmetic compositions and human and veterinary medicine
    23.
    发明授权
    Aromatic benzopyranyl and benzopyranyl compounds; their preparation; and their use in cosmetic compositions and human and veterinary medicine 失效
    芳香族苯并吡喃基和苯并吡喃基化合物; 他们的准备 以及它们在化妆品组合物和人兽药中的应用

    公开(公告)号:US4829080A

    公开(公告)日:1989-05-09

    申请号:US025200

    申请日:1987-03-12

    CPC分类号: C07D335/06 C07D311/58

    摘要: An aromatic benzopyranyl or benzothiopyranyl compound of the formula ##STR1## wherein n is 0 or 1,X represents ##STR2## R' represents H, OH, acyloxy or NH.sub.2, R" represents H or alkoxy orR' and R" taken together form an oxo, methano or hydroxyimino radical,R.sub.8 represents H, ##STR3## R.sub.9 represents H, alkyl, mono or polyhydroxyalkyl, aryl, aralkyl, a residue of a sugar or ##STR4## p equals 1, 2 or 3, r' and r" represent H, alkyl, monohydroxyalkyl, polyhydroxyalkyl, aryl, benzyl, the residue of an amino acid or an aminated sugar, or together form a heterocycle,R.sub.1, R.sub.2, R.sub.3 and R.sub.4 represents H or lower alkyl,R.sub.5, R.sub.6 and R.sub.7 represent H or methyl or when n=1, R.sub.5 and R.sub.7 taken together form with the benzene ring a naphthalene ring (R.sub.5 -R.sub.7 .dbd.--CH.dbd.CH--), andthe salts of said compounds as well as their geometric and optical isomers.These compounds are useful in pharmaceutical and cosmetic compositions.

    摘要翻译: 式(I)的芳香族苯并吡喃基或苯并硫代吡喃基化合物,其中n为0或1,X代表R'表示H,OH,酰氧基或NH 2,R“表示H或烷氧基或R'和R “一起形成氧代,亚甲基或羟基亚氨基,R8表示H,R 9表示H,烷基,单或多羟基烷基,芳基,芳烷基,糖残基或p等于1,2或3 ,r'和r“表示H,烷基,单羟基烷基,多羟基烷基,芳基,苄基,氨基酸或胺化糖的残基,或一起形成杂环,R 1,R 2,R 3和R 4表示H或低级烷基, R5,R6和R7表示H或甲基,或当n = 1时,R5和R7与苯环一起形成萘环(R5-R7 = -CH = CH-),所述化合物的盐以及它们的 几何和光学异构体。 这些化合物可用于药物和化妆品组合物。

    Substituted derivatives of thiamorpholinone
    28.
    发明授权
    Substituted derivatives of thiamorpholinone 失效
    噻吗啉酮的取代衍生物

    公开(公告)号:US4483983A

    公开(公告)日:1984-11-20

    申请号:US484605

    申请日:1983-04-13

    CPC分类号: C07D279/12

    摘要: A substituted derivative of thiamorpholinone, for use in the cosmetic and pharmaceutical field, has the formula ##STR1## wherein n is 0 or 1; R.sub.1 and R.sub.2 each independently represent hydrogen or lower alkyl and R.sub.3 represents hydrogen, mono or polyhydroxyalkyl containing 2-16 carbon atoms, carbamylalkyl, carboxyalkyl or alkoxycarbonylalkyl. When R.sub.3 represents hydrogen, R.sub.4 represents --CO.sub.2 R.sub.5 wherein R.sub.5 is alkyl having 3-18 carbon atoms, optionally interrupted by one or more heteroatoms, or mono or polyhydroxyalkyl having 2-18 carbon atoms. When R.sub.3 represents mono or polyhydroxyalkyl, carbamylalkyl, carboxyalkyl or alkoxycarbonylalkyl, R.sub.4 represents hydrogen or lower alkyl.

    摘要翻译: 用于化妆品和药物领域的噻吗啉酮的取代衍生物具有下式:其中n为0或1; R 1和R 2各自独立地表示氢或低级烷基,R 3表示氢,含有2〜16个碳原子的单或多羟基烷基,氨基甲酰基烷基,羧基烷基或烷氧基羰基烷基。 当R 3表示氢时,R 4表示-CO 2 R 5,其中R 5是具有3-18个碳原子的烷基,任选地被一个或多个杂原子间隔或具有2-18个碳原子的单羟基或多羟基烷基。 当R 3表示单或多羟基烷基,氨基甲酰基烷基,羧基烷基或烷氧基羰基烷基时,R 4表示氢或低级烷基。