公开(公告)号：US20170256091A1

公开(公告)日：2017-09-07

申请号：US15441930

申请日：2017-02-24

申请人： Paul Price

发明人： Paul Price

IPC分类号： G06T15/08 ,  G06T19/20 ,  G06T15/20

CPC分类号： G06T15/08 ,  G03B35/02 ,  G03B37/02 ,  G06F3/04815 ,  G06F3/04817 ,  G06F3/04845 ,  G06F3/0488 ,  G06Q10/087 ,  G06Q30/0623 ,  G06Q30/0643 ,  G06T15/205 ,  G06T19/20 ,  G06T2219/2016

摘要： A method and apparatus are provided to allow the viewing of an item from several virtual positions for evaluation and potential purchase. The information, including photographs, about the item is made available using the Internet.

公开(公告)号：US08785194B2

公开(公告)日：2014-07-22

申请号：US12463371

申请日：2009-05-08

申请人： Stephen Gorfien ,  Richard Fike ,  Glenn Godwin ,  Joyce Dzimian ,  David A. Epstein ,  Dale Gruber ,  Don McClure ,  Paul Price

发明人： Stephen Gorfien ,  Richard Fike ,  Glenn Godwin ,  Joyce Dzimian ,  David A. Epstein ,  Dale Gruber ,  Don McClure ,  Paul Price

IPC分类号： A61K33/00 ,  A61K33/26 ,  A61K33/32 ,  C12N5/00 ,  C12N5/02 ,  C12N5/07 ,  C12N5/10

CPC分类号： C12N5/0682 ,  C07K14/61 ,  C12N5/0037 ,  C12N5/0043 ,  C12N5/005 ,  C12N5/0603 ,  C12N7/00 ,  C12N9/2402 ,  C12N9/2471 ,  C12N15/85 ,  C12N2500/14 ,  C12N2500/16 ,  C12N2500/22 ,  C12N2500/24 ,  C12N2500/32 ,  C12N2500/34 ,  C12N2500/35 ,  C12N2500/38 ,  C12N2500/74 ,  C12N2500/76 ,  C12N2500/90 ,  C12N2500/95 ,  C12N2501/90 ,  C12N2501/91 ,  C12N2710/10051 ,  C12Y302/01023

摘要： The present invention provides a cell culture medium formulation that supports the in vitro cultivation, particularly in suspension, of mammalian cells, particularly epithelial cells and fibroblast cells, and methods for cultivating mammalian cells in suspension in vitro using these media. The media comprise a basal medium and a polyanionic or polyanionic compound, preferably a polysulfonated or polysulfated compound, and more preferably dextran sulfate. The present invention also provides chemically defined, protein-free eukaryotic cell culture media comprising an iron chelate and zinc, which is capable of supporting the growth (and particularly the high-density growth of mammalian cells) in suspension culture, increasing the level of expression of recombinant protein in cultured cells, and/or increasing virus production in cultured cells.

摘要翻译： 本发明提供了支持哺乳动物细胞，特别是上皮细胞和成纤维细胞的体外培养，特别是悬浮液的细胞培养基制剂，以及使用这些培养基在体外悬浮培养哺乳动物细胞的方法。 培养基包含基础培养基和聚阴离子或聚阴离子化合物，优选多磺化或多硫酸化合物，更优选硫酸葡聚糖。 本发明还提供化学上定义的，无蛋白质的真核细胞培养基，其包含铁螯合物和锌，其能够支持悬浮培养物中的生长（特别是哺乳动物细胞的高密度生长），从而增加表达水平 的培养细胞中的重组蛋白，和/或增加培养细胞中的病毒产生。

公开(公告)号：US20090061516A1

公开(公告)日：2009-03-05

申请号：US12209078

申请日：2008-09-11

申请人： Paul Price ,  Steven Gorfien ,  Douglas Danner ,  Mark Plavsic

发明人： Paul Price ,  Steven Gorfien ,  Douglas Danner ,  Mark Plavsic

IPC分类号： C12N5/06

CPC分类号： C12N5/0043 ,  C12N5/06 ,  C12N2500/12 ,  C12N2500/20 ,  C12N2500/32 ,  C12N2500/34 ,  C12N2500/36 ,  C12N2500/40 ,  C12N2500/74 ,  C12N2500/76 ,  C12N2500/90 ,  C12N2500/92 ,  C12N2501/11

摘要： The present invention provides serum-free cell culture media formulations which are capable of supporting the in vitro cultivation of animal cells. The media comprise at least one nutrient of non-animal derivation, such as at least one plant peptide and/or at least one non-animal or plant lipid and/or fatty acid. The media may further optionally comprise an enzymatic digest or extract of yeast cells. The present invention also provides methods of cultivating animal cells in vitro using these cell culture media formulations. In addition, the media of tile present invention can be used for growth of animal cells for virus production.

摘要翻译： 本发明提供能够支持体外培养动物细胞的无血清细胞培养基制剂。 培养基包含至少一种非动物衍生营养素，例如至少一种植物肽和/或至少一种非动物或植物脂质和/或脂肪酸。 培养基还可以任选地包含酵母细胞的酶促消化或提取物。 本发明还提供了使用这些细胞培养基制剂在体外培养动物细胞的方法。 此外，瓦片本发明的介质可用于生产用于病毒生产的动物细胞。

公开(公告)号：US20050240848A1

公开(公告)日：2005-10-27

申请号：US11109844

申请日：2005-04-20

申请人： Jean-Francois Cote ,  Paul Price ,  Benoit Nadeau-Dostie

发明人： Jean-Francois Cote ,  Paul Price ,  Benoit Nadeau-Dostie

IPC分类号： G01R31/28 ,  G01R31/3185

CPC分类号： G01R31/318572

摘要： A masking circuit for selectively masking scan chain inputs and/or outputs during scan testing of an integrated circuit, comprises a mask register having at least two mask register elements for each scan chain to provide a plurality of masking modes; and an input and output mask control circuit for each scan chain, each mask control circuit being connected between a test pattern source and a signature register and between a serial input and a serial output of an associated scan chain and being responsive to mask control data stored in the register elements for configuring the associated scan chain in one of the plurality of masking modes during a scan test of the circuit.

摘要翻译： 一种屏蔽电路，用于在集成电路的扫描测试期间有选择地屏蔽扫描链输入和/或输出，包括屏蔽寄存器，其具有用于每个扫描链的至少两个屏蔽寄存器元件，以提供多个屏蔽模式; 以及用于每个扫描链的输入和输出掩模控制电路，每个掩模控制电路连接在测试图案源和签名寄存器之间，并且连接在相关联的扫描链的串行输入和串行输出之间，并响应于存储的掩码控制数据 在用于在电路的扫描测试期间用于将多个掩模模式中的一个掩模模式中的一个配置为关联的扫描链的寄存器元件中。

公开(公告)号：US20050226884A1

公开(公告)日：2005-10-13

申请号：US11073333

申请日：2005-03-04

申请人： Paul Price ,  Julia Johansen

发明人： Paul Price ,  Julia Johansen

IPC分类号： A61K31/711 ,  A61K39/395 ,  A61K45/00 ,  A61K48/00 ,  A61P19/02 ,  A61P31/00 ,  A61P35/00 ,  C07K16/18 ,  C12Q1/68 ,  G01N33/53 ,  G01N33/574 ,  G01N33/577 ,  G01N33/68

CPC分类号： C07K16/18 ,  A61K2039/505 ,  C12Q1/6886 ,  C12Q2600/106 ,  C12Q2600/118 ,  C12Q2600/136 ,  G01N33/57488 ,  G01N2800/52

摘要： This invention provides methods for detecting cancers and for evaluating the prognosis of cancer patients. In particular, the methods of this invention utilize YKL-40 as a marker for the presence or absence of a cancer and for the prognosis (e.g. likelihood of recurrence) of a cancer. Elevated levels of YKL-40 are indicative of the presence of a cancer in undiagnosed subjects and indicate likely recurrence of the cancer in subjects diagnosed as having a cancer.

摘要翻译： 本发明提供了用于检测癌症并评价癌症患者预后的方法。 特别地，本发明的方法利用YKL-40作为癌症的存在或不存在以及癌症的预后（例如复发的可能性）的标志物。 YKL-40水平升高表明未确诊的受试者存在癌症，并表明诊断患有癌症的受试者可能会复发癌症。

公开(公告)号：US20050028978A1

公开(公告)日：2005-02-10

申请号：US10644429

申请日：2003-08-20

申请人： Mehmet Parlar ,  Liz Morris ,  Yiyan Chen ,  Paul Price

发明人： Mehmet Parlar ,  Liz Morris ,  Yiyan Chen ,  Paul Price

IPC分类号： C09K8/36 ,  E21B43/04

CPC分类号： C09K8/36 ,  C09K2208/30 ,  E21B43/04

摘要： A method is disclosed for using aqueous VES-based gravel carrier fluids in gravel packing operations using screens and shunt tubes that have been run into a well completed with an oil-based mud. With this method, the previously necessary but undesirable steps of first running in a perforated liner and then displacing the oil-based mud with an aqueous-based fluid in the region to be gravel packed are both avoided while the advantages of gravel packing with an aqueous-based fluid are retained.

摘要翻译： 公开了一种在使用已经用油基泥浆完成的筛网和分流管的砾石包装操作中使用水性VES基砾石载体流体的方法。 使用这种方法，首先在穿孔衬里中运行，然后在要砾石填充的区域中用含水基流体移动油基泥浆的先前必要但不期望的步骤都是避免的，而具有水性的砾石填充的优点 的流体被保留。