Method and apparatus for detecting bio-complexes using rule-based templates
    24.
    发明申请
    Method and apparatus for detecting bio-complexes using rule-based templates 有权
    使用基于规则的模板检测生物复合物的方法和装置

    公开(公告)号:US20070136001A1

    公开(公告)日:2007-06-14

    申请号:US11635553

    申请日:2006-12-08

    IPC分类号: G06F19/00

    CPC分类号: G06F19/12 G06F19/24

    摘要: Provided are a method and apparatus for detecting bio-complexes that are important sub protein interaction networks using a rule-based template in large interaction networks present in a single species. The method includes (a) defining a rule-based template corresponding to a bio-complex to be detected by defining a node that consists of at least one protein, a triplet that consists of two defined nodes and a protein interaction relationship therebetween, and single and composite rules using the triplet and an operator; (b) analyzing the rules of the defined rule-based template by analyzing whether the protein corresponding to the node included in the defined rule-based template and the protein interaction relationship corresponding to the triplet are present in a protein interaction network; and (c) detecting a bio-complex in the protein interaction network by assessing the triplet included in the rules analyzed and the node included in the triplet using a protein interaction relationship and protein of the protein interaction networks.

    摘要翻译: 提供了一种用于检测生物复合物的方法和装置,其是在单个物种中存在的大型相互作用网络中使用基于规则的模板的重要的亚蛋白质相互作用网络。 该方法包括(a)通过定义由至少一个蛋白质组成的节点,由两个定义的节点组成的三联体以及它们之间的蛋白质相互作用关系来定义与要检测的生物复合物相对应的基于规则的模板,以及单个 和使用三元组和运算符的复合规则; (b)通过分析蛋白质相互作用网络中是否存在与定义的基于规则的模板中包含的节点相对应的蛋白质和对应于三联体的蛋白质相互作用关系来分析所定义的基于规则的模板的规则; 和(c)通过使用蛋白质相互作用网络的蛋白质相互作用关系和蛋白质评估包含在所分析的规则中的三联体和包含在三联体中的节点来检测蛋白质相互作用网络中的生物复合物。

    Bifrequency output device
    25.
    发明授权
    Bifrequency output device 有权
    双频输出设备

    公开(公告)号:US6087884A

    公开(公告)日:2000-07-11

    申请号:US140319

    申请日:1998-08-26

    CPC分类号: H03K17/92 H03K3/38

    摘要: There is disclosed a bifrequency output device. The bifrequency output device comprises Josephson junctions, a resistor for generating a given voltage in response to a pulse current which is supplied from the outside, and a time delay element for delaying the voltage generated by the resistor during a given time period and then providing it to the superconducting elements, so that the bifrequency output device outputs different low frequency and low voltage and high frequency and high voltage depending on the initial condition of the superconducting elements constituting the Josephson junctions and the voltage with a given delay time which is induced to the superconducting elements.

    摘要翻译: 公开了一种双频输出装置。 双频输出装置包括约瑟夫逊结,用于响应于从外部提供的脉冲电流产生给定电压的电阻器,以及用于在给定时间段内延迟由电阻器产生的电压然后提供给它的时间延迟元件 使得双频输出装置根据构成约瑟夫逊结的超导元件的初始条件和给定延迟时间的电压输出不同的低频和低电压以及高频和高电压,该延迟时间被诱导到 超导元件

    2-benzoyl-3-aminoacrylate derivatives and methods for the preparation of
the same
    26.
    发明授权
    2-benzoyl-3-aminoacrylate derivatives and methods for the preparation of the same 失效
    2-苯甲酰基-3-氨基丙烯酸酯衍生物及其制备方法

    公开(公告)号:US5491251A

    公开(公告)日:1996-02-13

    申请号:US321370

    申请日:1994-10-11

    CPC分类号: C07C229/34

    摘要: 2-benzoyl-3-aminoacrylate derivatives of the following formula I and methods for the preparation of the same. ##STR1## wherein X is a halogen; X.sub.1 and X.sub.2 are independently selected from a halogen and a nitro; and R, R.sub.1 and R.sub.2 each is an alkyl group containing 1 to 4 carbon atoms. The compounds can be used as starting materials to synthesize benzoxazine derivatives, potent antibacterial compounds.

    摘要翻译: 下式I的2-苯甲酰基-3-氨基丙烯酸酯衍生物及其制备方法。 其中X是卤素; X1和X2独立地选自卤素和硝基; R 1,R 2和R 2各自为含有1〜4个碳原子的烷基。 该化合物可用作原料合成苯并恶嗪衍生物,有效的抗菌化合物。

    Portable digital reader for urinalysis
    27.
    发明授权
    Portable digital reader for urinalysis 有权
    便携式数字读取器用于尿液分析

    公开(公告)号:US08797536B2

    公开(公告)日:2014-08-05

    申请号:US13390506

    申请日:2010-03-05

    IPC分类号: G01N21/59

    摘要: The present invention relates to a portable digital reader for reading an analysis target chip including a plurality of test areas. The reader comprises: a light emitting section having light emitting elements for radiating light; an integral optical splitter for uniformly distributing the light from the light emitting section to each test area of the analysis target chip; a light receiving section for receiving light reflected from each test area so as to convert the same into electric signals; and a measuring section for measuring concentration according to the electric signals obtained from the light receiving section. Therefore, it is possible to prevent the generation of errors in signal measurement due to optical distribution failure by assembling branch sections of the optical splitter under the control of the number of the branch sections according to the number of test items in a test strip.

    摘要翻译: 本发明涉及用于读取包括多个测试区域的分析目标芯片的便携式数字读取器。 读取器包括:发光部,其具有用于发光的发光元件; 用于将来自发光部分的光均匀分布到分析目标芯片的每个测试区域的整体光分路器; 光接收部分,用于接收从每个测试区域反射的光,以将其转换为电信号; 以及用于根据从光接收部获得的电信号来测量浓度的测量部分。 因此,可以根据测试条中的测试项目的数量,在分支部分的数量的控制下组装光分路器的分支部分来防止由于光分布故障而导致的信号测量误差的产生。

    Measurement device equipped with device for deciding measurement start point
    29.
    发明授权
    Measurement device equipped with device for deciding measurement start point 有权
    测量装置配备了用于决定测量起点的装置

    公开(公告)号:US08228502B2

    公开(公告)日:2012-07-24

    申请号:US12545170

    申请日:2009-08-21

    IPC分类号: G01J3/28

    摘要: Provided is a measurement device. The measurement device includes a sensor, a wavelength-tunable light source, an additional light source, a coupler, and an optical power measurer. The sensor accepts a sample. The wavelength-tunable light source irradiates wavelength-tunable light to detect a reaction of the sensor. The additional light source irradiates wavelength-fixed light to detect an initial time of the reaction. The coupler combines the wavelength-tunable light source and the additional light source and irradiates the combined input light on the sensor. The optical power measurer detects the reaction of the sensor from an output light transmitted through or reflected by the sensor.

    摘要翻译: 提供了一种测量装置。 测量装置包括传感器,波长可调光源,附加光源,耦合器和光功率测量器。 传感器接受样品。 波长可调光源照射波长可调光以检测传感器的反应。 附加的光源照射波长固定的光以检测反应的初始时间。 耦合器将波长可调光源和附加光源相结合,并将传感器上的组合输入光照射。 光功率测量器检测传感器从传感器传输或反射的输出光的反应。

    BIOCHIP AND METHOD OF DETECTING REACTION FROM THE SAME
    30.
    发明申请
    BIOCHIP AND METHOD OF DETECTING REACTION FROM THE SAME 审中-公开
    检测反应物的生物学和方法

    公开(公告)号:US20110091905A1

    公开(公告)日:2011-04-21

    申请号:US12893166

    申请日:2010-09-29

    CPC分类号: G01N33/5302 G01N21/31

    摘要: Provided are a biochip and a method of detecting a reaction from the biochip. This method includes preparing a first mixture solution of polyvinylpyrrolidone (PVP) and a sample including target molecules, measuring absorbance or transmittance of the first mixture solution, preparing a second mixture solution including the PVP, the sample, and a receptor of the target molecules, measuring absorbance or transmittance of the second mixture solution, and calculating an absorbance or transmittance difference between the first mixture solution and the second mixture solution. Thus, it is possible to reduce the production cost of the biochip by inducing a reaction of an antigen and an antibody using PVP. Further, it is possible to detect an accurate quantity of the antigen by analyzing a quantity of antigen on the basis of the absorbance or transmittance difference.

    摘要翻译: 提供了一种生物芯片和从生物芯片检测反应的方法。 该方法包括制备聚乙烯吡咯烷酮(PVP)的第一混合溶液和包含靶分子的样品,测量第一混合溶液的吸光度或透射率,制备包含PVP,样品和靶分子的受体的第二混合溶液, 测量第二混合溶液的吸光度或透射率,并计算第一混合溶液和第二混合溶液之间的吸光度或透射率差异。 因此,通过使用PVP诱导抗原和抗体的反应,可以降低生物芯片的生产成本。 此外,可以通过基于吸光度或透射率差异分析抗原量来检测精确量的抗原。