公开(公告)号：US11662344B2

公开(公告)日：2023-05-30

申请号：US16438215

申请日：2019-06-11

Applicant: Inguran, LLC

Inventor： Kristie Krug

IPC: G01N33/543 ,  B03C1/015 ,  B03C1/02 ,  B03C1/023 ,  B03C1/01 ,  B03C1/28 ,  C12N13/00 ,  G01N33/569

CPC classification number: G01N33/5434 ,  B03C1/01 ,  B03C1/015 ,  B03C1/02 ,  B03C1/023 ,  B03C1/288 ,  C12N13/00 ,  G01N33/54333 ,  G01N33/54346 ,  G01N33/54353 ,  G01N33/56966 ,  B03C2201/18 ,  B03C2201/26

Abstract: A method for magnetic cellular manipulation may include contacting a composition with a biological sample to form a mixture. The composition may include a plurality of particles. Each particle in the plurality of particles may include a magnetic substrate. The magnetic substrate may be characterized by a magnetic susceptibility greater than zero. The composition may also include a chargeable silicon-containing compound. The chargeable silicon-containing compound may coat at least a portion of the magnetic substrate. The biological sample may include cells and/or cellular structures. The method may also include applying a magnetic field to the mixture to manipulate the composition.

公开(公告)号：US20230149949A1

公开(公告)日：2023-05-18

申请号：US18092753

申请日：2023-01-03

Applicant: Fleenor Manufacturing, Inc.

Inventor： Jeff Fleenor ,  Kurtis Stockdale

IPC: B03C3/66 ,  B03C1/033 ,  B03C1/034 ,  B03C1/28 ,  B03C1/30 ,  B03C3/47 ,  B03C3/82

CPC classification number: B03C3/66 ,  B03C1/0332 ,  B03C1/034 ,  B03C1/288 ,  B03C1/284 ,  B03C1/30 ,  B03C1/286 ,  B03C3/47 ,  B03C3/82 ,  B03C2201/18 ,  B03C2201/28

Abstract: A filter for removing ferrous particles from a fluid. The filter has an outer filter housing and a non-ferrous liner inside the housing. A plurality of magnets are longitudinally extended at intervals outside the liner. An insert inside the liner imparting a directional flow to the fluid inside the filter whereby ferrous particles in the fluid are trapped by the magnets and held against the non-ferrous line.

公开(公告)号：US20230149945A1

公开(公告)日：2023-05-18

申请号：US18055948

申请日：2022-11-16

Applicant: Royal Biotech Inc

Inventor： Philip Huang ,  E-Ray Huang

IPC: B03B9/06 ,  B03D1/02 ,  B03B5/30 ,  B03B13/02 ,  B03C1/30 ,  B03C1/01

CPC classification number: B03B9/061 ,  B03D1/028 ,  B03B5/30 ,  B03B13/02 ,  B03C1/30 ,  B03C1/01 ,  B03C2201/18

Abstract: The method of the present invention receives a mixture. The method then separates clay and metal within in the mixture. The method then treats pollutants or toxins within in the mixture with magnetic beads. The method then treats the pollutants or toxins using nano-bubbles generated by a 3-in-1 bubble generator. Further, the method screens and classifies the tiny particles within in the mixture based on magnetic separation. Next the method screens and classifies the tiny particles within in the mixture based on gravity separation. The gravity separation includes an anti-leakage net underneath the grinding system. The anti-leakage net avoids loss and collects and resets the leakage into a feeding port connected to the gravitational device. Furthermore, the method screens and classifies the tiny particles within in the mixture based on floatation. Finally, the method collects the target element and rare earth elements (REE).

公开(公告)号：US20190221289A1

公开(公告)日：2019-07-18

申请号：US16336344

申请日：2017-09-22

Applicant: ArcherDX, Inc.

Inventor： Joshua Stahl ,  Jason Myers

IPC: G16B30/00 ,  G16B35/00 ,  G16B25/20 ,  C12Q1/68 ,  B01L3/00

CPC classification number: G16B30/00 ,  B01L3/502761 ,  B01L3/50825 ,  B01L7/52 ,  B01L2200/0668 ,  B01L2300/021 ,  B01L2300/0816 ,  B01L2300/0887 ,  B01L2300/1822 ,  B01L2400/043 ,  B01L2400/0644 ,  B03C1/01 ,  B03C1/0332 ,  B03C1/288 ,  B03C1/30 ,  B03C2201/18 ,  B03C2201/26 ,  C07H21/00 ,  C12Q1/68 ,  C12Q1/6806 ,  C40B30/06 ,  F04C14/14 ,  G01N1/34 ,  G01N30/04 ,  G01N30/6091 ,  G01N33/54326 ,  G01N35/0098 ,  G01N35/02 ,  G01N2030/8827 ,  G01N2035/00564 ,  G16B25/20 ,  G16B35/00 ,  C12Q2563/143 ,  C12Q2563/149

Abstract: Biological analysis system and methods for operating devices of the system are provided. A library preparation device of the biological analysis system may perform a library preparation protocol on a biological sample, where the library preparation protocol is determined based on information from an encoded identifier associated with the biological sample and a resource to be used by the library preparation device. A sequencing device may perform a sequencing process on a library prepared by the library preparation device. Configuration of the sequencing device to perform the process may include receiving sample information generated by the library preparation device and processing the sample information to generate configuration information for the sequencing device. Results from the sequencing process may be analyzed to determine nucleic acid sequences based on the sample information.

公开(公告)号：US20190030535A1

公开(公告)日：2019-01-31

申请号：US15878213

申请日：2018-01-23

Applicant: The General Hospital Corporation

Inventor： Kyle C. Smith ,  Ramin Haghgooie ,  Thomas Alan Barber ,  Ismail Emre Ozkumur ,  Ravi Kapur ,  Mehmet Toner

IPC: B01L3/00 ,  B03C1/033 ,  G01N33/543 ,  G01N1/40 ,  B03C1/28 ,  G01N33/487

CPC classification number: B01L3/502761 ,  B01L2200/0652 ,  B01L2200/0668 ,  B01L2200/12 ,  B01L2300/06 ,  B01L2300/12 ,  B01L2400/043 ,  B03C1/0332 ,  B03C1/288 ,  B03C2201/18 ,  B03C2201/22 ,  B03C2201/26 ,  G01N1/4077 ,  G01N33/48735 ,  G01N33/54333

Abstract: This disclosure describes microfluidic devices that include one or more magnets, each magnet being operable to emit a magnetic field; and a magnetizable layer adjacent to the one or more magnets, in which the magnetizable layer is configured to induce a gradient in the magnetic field of at least one of the magnets. For example, the gradient can be at least 103 T/m at a position that is at least 20 μm away from a surface of the magnetizable layer. The magnetizable layer includes a first high magnetic permeability material and a low magnetic permeability material arranged adjacent to the high magnetic permeability material. The devices also include a microfluidic channel arranged on a surface of the magnetizable layer, wherein a central longitudinal axis of the microfluidic channel is arranged at an angle to or laterally offset from an interface between the high magnetic permeability material and the low magnetic permeability material.

公开(公告)号：US20180264484A1

公开(公告)日：2018-09-20

申请号：US15885586

申请日：2018-01-31

Applicant: Robert Bosch GmbH

Inventor： Oliver Gaertner

IPC: B03C1/28 ,  B60T8/36 ,  F15B21/04

CPC classification number: B03C1/286 ,  B03C1/0332 ,  B03C1/288 ,  B03C2201/18 ,  B03C2201/20 ,  B03C2201/30 ,  B60T8/3615 ,  B60T8/368 ,  F15B21/041

Abstract: A hydraulic assembly for modulating a brake pressure of a wheel brake of a motor vehicle brake system with electronic slip control includes a housing block through which a brake fluid is configured to flow and which is equipped with an electronically controllable member for setting the brake pressure. The hydraulic assembly also includes at least one particle-filtering device that is fitted with the housing block and forms a magnetic field. Using the particle-filtering device, particles of ferromagnetic material are configured to be filtered out of the brake fluid without reducing a cross-section of a fluid-conducting channel and thereby choking the throughflow of the housing block or hindering the fluid throughflow.

公开(公告)号：US20180221890A1

公开(公告)日：2018-08-09

申请号：US15886618

申请日：2018-02-01

Applicant: FilterMag International, Inc.

Inventor： Randy Yount ,  Wayne Johnson

IPC: B03C1/28 ,  B03C1/033 ,  F01M11/03 ,  F01M11/04

CPC classification number: B03C1/286 ,  B03C1/0332 ,  B03C2201/18 ,  F01M1/10 ,  F01M11/03 ,  F01M11/0408 ,  F01M2001/1042 ,  F01M2011/0416 ,  F16N39/06

Abstract: A magnetic filtration device for installing as a replacement to a standard drain plug commonly positioned at the bottom of the reservoir. The magnetic filtration device may attract and capture magnetic (ferromagnetic) particulate circulating throughout a mechanical system. Applications for the device include engines, motors, pumps, compressors, gear boxes, transmissions, hydraulic systems, and generators. The magnetic filtration device may comprise a magnet core enclosed within a magnet casing, with additional magnetic rods affixed to and/or arranged around the magnet casing.

公开(公告)号：US20180188246A1

公开(公告)日：2018-07-05

申请号：US15740288

申请日：2016-07-01

Applicant: Ancera, Inc.

Inventor： Hur KOSER

IPC: G01N33/543 ,  B03C1/023 ,  B03C1/033 ,  B03C1/28 ,  B03C1/32

CPC classification number: G01N33/54333 ,  B03C1/023 ,  B03C1/0332 ,  B03C1/0335 ,  B03C1/288 ,  B03C1/32 ,  B03C2201/18 ,  B03C2201/26

Abstract: Devices, methods, and systems are provided for extracting particles from a ferrofluid and for rapid affinity measurements. Such systems may comprise a fluidic channel or chamber configured to include a ferrofluid having a plurality of target particles and background particles. The systems may include a capture region configured to capture at least a portion of the plurality of target particles. In addition, the systems include a first magnetic field generator and a second magnetic field generator. The first magnetic field generator may be arranged proximate to the fluidic channel, the first magnetic field generator being configured to generate a first magnetic field configured to direct the plurality of target particles towards the capture region. The second magnetic field generator can be arranged to be proximate to the capture region, and is further configured to generate an affinity thresholding magnetic field configured to remove background particles from the capture region.

公开(公告)号：US10010891B2

公开(公告)日：2018-07-03

申请号：US15831367

申请日：2017-12-04

Applicant: Kosky Yen ,  Peter Wu ,  Michael Lee ,  Charles Chen

Inventor： Kosky Yen ,  Peter Wu ,  Michael Lee ,  Charles Chen

IPC: B03C1/032 ,  B03C1/033 ,  B03C1/28

CPC classification number: B03C1/032 ,  B03C1/0332 ,  B03C1/0335 ,  B03C1/284 ,  B03C1/286 ,  B03C2201/18

Abstract: A high capacity magnetic filter for separating magnetic and non-magnetic contaminants from contaminated liquid streams includes a housing having (i) an interior region between the inlet and outlet for a process stream, (ii) a plurality of vertically oriented, elongated non-magnetic holder sleeves positioned within the interior region (iii) paramagnetic metal packing material that is randomly distributed in the interior region to form a packed compartment that has a void volume which is above 95 percent, and (iv) a device to generate a magnetic field within the interior region. Generation of a uniform magnetic field within the packed compartment magnetizes the holder sleeves and matrix of packing materials. The holder sleeves and matrix create a large surface area for collecting the contaminants.

公开(公告)号：US10006907B2

公开(公告)日：2018-06-26

申请号：US15184280

申请日：2016-06-16

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Mara Johanna Jacoba Sijbers ,  Petrus Johannes Wilhelmus Van Lankvelt ,  Femke Karina De Theije ,  Jeroen Hans Nieuwenhuis

IPC: G01N25/08 ,  G01N33/543 ,  B03C1/28 ,  G01N27/74 ,  G01N33/94

CPC classification number: G01N33/54333 ,  B03C1/282 ,  B03C1/288 ,  B03C2201/18 ,  B03C2201/26 ,  G01N27/745 ,  G01N33/54373 ,  G01N33/946 ,  G01N33/948 ,  G01N33/9486

Abstract: A cartridge for detection of target components in a liquid sample includes a sample chamber, at least two reservoirs that can be furnished with magnetic particles, and at least two corresponding sensitive zones in which solved magnetic particles and/or target components can be detected. When a magnetic actuation field of a given configuration is established in the sample chamber, the magnetic particles of different reservoirs migrate predominantly to different sensitive zones. Thus a mixing of magnetic particles can be avoided.