公开(公告)号：US08862197B2

公开(公告)日：2014-10-14

申请号：US13768916

申请日：2013-02-15

Applicant: Dexcom, Inc.

Inventor： Apurv Ullas Kamath ,  Peter C. Simpson ,  Mark Brister

IPC: A61B5/05 ,  A61B5/1459 ,  A61B5/00 ,  A61B5/145 ,  A61B5/1455 ,  A61B5/1495 ,  A61B5/1486

CPC classification number: A61B5/1455 ,  A61B5/14532 ,  A61B5/14542 ,  A61B5/14546 ,  A61B5/14551 ,  A61B5/1459 ,  A61B5/14865 ,  A61B5/1495 ,  A61B5/4094 ,  A61B5/6852 ,  A61B5/7203 ,  A61B2560/0223

Abstract: Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system.

Abstract translation: 提供了用于宿主血管系统的连续分析物测量的系统和方法。 在一些实施例中，连续葡萄糖测量系统包括血管通路装置，传感器和传感器电子装置，所述系统被配置为插入与主机的循环系统的通信。

公开(公告)号：US20140128837A1

公开(公告)日：2014-05-08

申请号：US14065847

申请日：2013-10-29

Applicant: DexCom, Inc.

Inventor： Naresh C. Bhavaraju ,  Arturo Garcia ,  Phil Mayou ,  Thomas A. Peyser ,  Apurv Ullas Kamath ,  Aarthi Mahalingam ,  Kevin Sayer ,  Thomas Hall ,  Michael Robert Mensinger ,  Hari Hampapuram ,  David Price ,  Jorge Valdes ,  Murrad Kazalbash

IPC: A61M5/172 ,  A61M5/142

CPC classification number: G06F19/30 ,  A61M5/142 ,  A61M5/1723 ,  G01N33/49 ,  G06F19/3418 ,  G16H40/63 ,  G16H50/30

Abstract: Methods and apparatus, including computer program products, are provided for processing analyte data. In some example implementations, a method may include generating glucose sensor data indicative of a host's glucose concentration using a glucose sensor; calculating a glycemic variability index (GVI) value based on the glucose sensor data; and providing output to a user responsive to the calculated glycemic variability index value. The GVI may be a ratio of a length of a line representative of the sensor data and an ideal length of the line. Related systems, methods, and articles of manufacture are also disclosed.

Abstract translation: 提供包括计算机程序产品在内的方法和装置用于处理分析物数据。 在一些示例性实施方式中，方法可以包括使用葡​​萄糖传感器生成指示宿主葡萄糖浓度的葡萄糖传感器数据; 基于葡萄糖传感器数据计算血糖变异指数（GVI）值; 以及响应于所计算的血糖变异指数值向用户提供输出。 GVI可以是表示传感器数据的线的长度与线的理想长度的比率。 还公开了相关系统，方法和制品。

公开(公告)号：US20140118138A1

公开(公告)日：2014-05-01

申请号：US13742694

申请日：2013-01-16

Applicant: DEXCOM, INC.

Inventor： Claudio Cobelli ,  Giovanni Sparacino ,  Andrea Facchinetti ,  Hari Hampapuram ,  Anna Leigh Rack-Gomer ,  Chiara Zecchin ,  Naresh C. Bhavaraju ,  Apurv Ullas Kamath

IPC: G08B21/02

CPC classification number: A61B5/746 ,  A61B5/0004 ,  A61B5/002 ,  A61B5/0022 ,  A61B5/0031 ,  A61B5/14503 ,  A61B5/14532 ,  A61B5/4848 ,  A61B5/4866 ,  A61B5/7221 ,  A61B5/7275 ,  G06F19/00

Abstract: Systems and methods for providing sensitive and specific alarms indicative of glycemic condition are provided herein. In an embodiment, a method of processing sensor data by a continuous analyte sensor includes: evaluating sensor data using a first function to determine whether a real time glucose value meets a first threshold; evaluating sensor data using a second function to determine whether a predicted glucose value meets a second threshold; activating a hypoglycemic indicator if either the first threshold is met or if the second threshold is predicted to be met; and providing an output based on the activated hypoglycemic indicator.

Abstract translation: 本文提供了用于提供指示血糖状况的敏感和特定警报的系统和方法。 在一个实施例中，通过连续分析物传感器处理传感器数据的方法包括：使用第一函数来评估传感器数据，以确定实时葡萄糖值是否满足第一阈值; 使用第二功能评估传感器数据，以确定预测的葡萄糖值是否满足第二阈值; 如果满足第一阈值或者如果预测到第二阈值被满足则激活低血糖指示剂; 并提供基于激活的低血糖指标的输出。

公开(公告)号：US20140046149A1

公开(公告)日：2014-02-13

申请号：US14058091

申请日：2013-10-18

Applicant: DexCom, Inc.

Inventor： Peter C. Simpson ,  Robert J. Boock ,  Apurv Ullas Kamath ,  Matthew D. Wightlin ,  Michael J. Estes

IPC: A61B5/145

CPC classification number: A61B5/1473 ,  A61B5/14503 ,  A61B5/1451 ,  A61B5/14517 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/14865 ,  A61B2560/0223 ,  A61B2562/0209 ,  A61B2562/043 ,  A61B2562/125 ,  B05C3/10

Abstract: Devices and methods are provided for continuous measurement of an analyte concentration. The device can include a sensor having a plurality of sensor elements, each having at least one characteristic that is different from other sensor(s) of the device. In some embodiments, the plurality of sensor elements are each tuned to measure a different range of analyte concentration, thereby providing the device with the capability of achieving a substantially consistent level of measurement accuracy across a physiologically relevant range. In other embodiments, the device includes a plurality of sensor elements each tuned to measure during different time periods after insertion or implantation, thereby providing the sensor with the capability to continuously and accurately measure analyte concentrations across a wide range of time periods. For example, a sensor system 180 is provided having a first working electrode 150 comprising a first sensor element 102 and a second working electrode 160 comprising a second sensor element 104, and a reference electrode 108 for providing a reference value for measuring the working electrode potential of the sensor elements 102, 104.

Abstract translation: 提供了用于连续测量分析物浓度的装置和方法。 该装置可以包括具有多个传感器元件的传感器，每个传感器元件具有与装置的其它传感器不同的至少一个特性。 在一些实施例中，多个传感器元件各自被调谐以测量分析物浓度的不同范围，从而为器件提供在生理学相关范围内实现基本一致的测量精度水平的能力。 在其他实施例中，该装置包括多个传感器元件，每个传感器元件在插入或植入之后的不同时间期间被调整以测量，从而为传感器提供在宽范围的时间段内连续且精确地测量分析物浓度的能力。 例如，传感器系统180被提供有具有包括第一传感器元件102的第一工作电极150和包括第二传感器元件104的第二工作电极160以及用于提供用于测量工作电极电位的参考值的参考电极108 的传感器元件102,104。

公开(公告)号：US20130150692A1

公开(公告)日：2013-06-13

申请号：US13742178

申请日：2013-01-15

Applicant: DexCom, Inc.

Inventor： Apurv Ullas Kamath ,  John Michael Dobbles ,  Aarthi Mahalingam

IPC: A61B5/1477 ,  A61B5/145 ,  A61B5/00

CPC classification number: A61B5/1477 ,  A61B5/0004 ,  A61B5/14532 ,  A61B5/14865 ,  A61B5/1495 ,  A61B5/6833 ,  A61B5/7203 ,  A61B5/725 ,  A61B5/7264 ,  A61B5/7275 ,  A61B5/7278 ,  A61B5/742 ,  A61B5/743

Abstract: Systems and methods for processing sensor data are provided. In some embodiments, systems and methods are provided for calibration of a continuous analyte sensor. In some embodiments, systems and methods are provided for classification of a level of noise on a sensor signal. In some embodiments, systems and methods are provided for determining a rate of change for analyte concentration based on a continuous sensor signal. In some embodiments, systems and methods for alerting or alarming a patient based on prediction of glucose concentration are provided.

公开(公告)号：US20250166815A1

公开(公告)日：2025-05-22

申请号：US19030660

申请日：2025-01-17

Applicant: Dexcom, Inc.

Inventor： Shawn Larvenz ,  Katherine Yerre Koehler ,  Apurv Ullas Kamath ,  Rian W. Draeger ,  Subrai G. Pai

IPC: G16H40/63 ,  A61B5/00 ,  A61B5/145 ,  G16H10/40 ,  G16H20/10 ,  G16H20/40 ,  G16H40/67 ,  G16H50/20

Abstract: “Zero-click” viewing of sensor data without any user input is provided. A display with sensor data may be “always on,” and may enable discrete viewing of sensor data without significant user hassle. Also, a system may be configured to display only current data, and/or to display the most current data for only a set interval. Also, one device in a continuous analyte monitoring system may be designated as a primary device, or hub, for receiving sensor data, and may control the flow of information and/or alerts to other devices in the system. Sensor data and/or alerts may be sent to a hierarchy of devices and/or persons in a designated order.

公开(公告)号：US20250166780A1

公开(公告)日：2025-05-22

申请号：US19029581

申请日：2025-01-17

Applicant: Dexcom, Inc.

Inventor： Anna Leigh Davis ,  Hari Hampapuram ,  Apurv Ullas Kamath ,  Eli Reihman ,  Leif N. Bowman ,  Arturo Garcia ,  Katherine Yerre Koehler ,  Naresh C. Bhavaraju ,  Rian Draeger ,  Paul Kramer ,  Paul Noble-Campbell

IPC: G16H20/30 ,  A61B5/00 ,  A61B5/01 ,  A61B5/11 ,  A61B5/145 ,  A61B5/16 ,  A61M5/172 ,  A61M5/50 ,  G06F3/04817 ,  G06F3/04847 ,  G16H20/60 ,  G16H40/63

Abstract: Systems and methods are disclosed that employ several or numerous factors in the determination of a glycemic urgency index (GUI), which may be based on a measured blood glucose level as well as other factors. The other factors may include time derivatives of the glucose level and/or other factors, e.g., user-entered data, data measured by other sensors or received from a network source, or historical data. The GUI is then presented to the user in an interesting way, e.g., via a background color or other inconspicuous notifier, e.g., on a mobile device such as a smart phone. The GUI may also be employed in the triggering of actionable alerts and alarms on an electronic device for the user. The GUI, or another index calculated from combinations of the variables and parameters described, may further be employed to drive a medicament delivery device such as a pump.

公开(公告)号：US12047381B2

公开(公告)日：2024-07-23

申请号：US18483473

申请日：2023-10-09

Applicant: Dexcom, Inc.

Inventor： Apurv Ullas Kamath ,  Michael Robert Mensinger ,  Nicholas Polytaridis ,  Gary A. Morris ,  Alexandra Elena Constantin ,  Douglas William Burnette ,  Mario Remon ,  Jorge R. Barreras ,  Benjamin Elrod West ,  Christopher Robert Hannemann

IPC: H04L9/40 ,  A61B5/00 ,  A61B5/145 ,  G16H10/60 ,  G16H10/65 ,  G16H40/40 ,  G16H50/20 ,  H04W4/38 ,  H04W12/06 ,  H04W52/02 ,  H04W76/14 ,  A61B5/1495 ,  H04W4/80

CPC classification number: H04L63/101 ,  A61B5/14532 ,  A61B5/686 ,  G16H10/60 ,  G16H10/65 ,  G16H50/20 ,  H04W12/06 ,  H04W52/0277 ,  H04W76/14 ,  A61B5/0002 ,  A61B5/0004 ,  A61B5/14503 ,  A61B5/14546 ,  A61B5/1495 ,  A61B5/486 ,  A61B5/7445 ,  A61B5/746 ,  H04L2209/88 ,  H04W4/38 ,  H04W4/80

Abstract: Systems, devices, and methods are disclosed for wireless communication of analyte data. In embodiments, a method of using a diabetes management partner interface to configure an analyte sensor system for wireless communication with a plurality of partner devices is provided. The method includes the analyte sensor system receiving authorization to provide one of the partner devices with access to a set of configuration parameters via the diabetes management partner interface. The set of configuration parameters is stored in a memory of the analyte sensor system. The method also includes, responsive to input received from the one partner device via the diabetes management partner interface, the analyte sensor system setting or causing a modification to the set of configuration parameters, according to a system requirement of the one partner device.

公开(公告)号：US12011266B2

公开(公告)日：2024-06-18

申请号：US18145220

申请日：2022-12-22

Applicant: Dexcom, Inc.

Inventor： Peter C. Simpson ,  Robert J. Boock ,  Apurv Ullas Kamath ,  Matthew D. Wightlin ,  Michael J. Estes

IPC: A61B5/1486 ,  A61B5/145 ,  A61B5/1473 ,  B05C3/02 ,  B05C3/10 ,  B05C3/12 ,  B23K26/362 ,  B05C5/02 ,  B05D1/18 ,  B05D3/06 ,  B23K26/08 ,  C23C2/00

CPC classification number: A61B5/1473 ,  A61B5/14503 ,  A61B5/1451 ,  A61B5/14517 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/14865 ,  B05C3/02 ,  B05C3/10 ,  B05C3/125 ,  B23K26/362 ,  A61B2560/0223 ,  A61B2562/0209 ,  A61B2562/043 ,  A61B2562/125 ,  B05C5/0241 ,  B05D1/18 ,  B05D3/06 ,  B23K26/0823 ,  B29C2791/009 ,  C23C2/00

Abstract: Devices and methods are provided for continuous measurement of an analyte concentration. The device can include a sensor having a plurality of sensor elements, each having at least one characteristic that is different from other sensor(s) of the device. In some embodiments, the plurality of sensor elements are each tuned to measure a different range of analyte concentration, thereby providing the device with the capability of achieving a substantially consistent level of measurement accuracy across a physiologically relevant range. In other embodiments, the device includes a plurality of sensor elements each tuned to measure during different time periods after insertion or implantation, thereby providing the sensor with the capability to continuously and accurately measure analyte concentrations across a wide range of time periods. For example, a sensor system 180 is provided having a first working electrode 150 comprising a first sensor element 102 and a second working electrode 160 comprising a second sensor element 104, and a reference electrode 108 for providing a reference value for measuring the working electrode potential of the sensor elements 102, 104.

公开(公告)号：US11879887B2

公开(公告)日：2024-01-23

申请号：US17523673

申请日：2021-11-10

Applicant: DexCom, Inc.

Inventor： Naresh C. Bhavaraju ,  Arturo Garcia ,  Hari Hampapuram ,  Apurv Ullas Kamath ,  Aarthi Mahalingam ,  Dmytro Sokolovskyy ,  Stephen J. Vanslyke

IPC: G01N33/487 ,  G16C20/80 ,  G16C99/00 ,  A61B5/00 ,  G01M99/00 ,  A61B5/145 ,  A61B5/1495 ,  G01N33/49 ,  G01N33/66

CPC classification number: G01N33/48792 ,  A61B5/1495 ,  A61B5/14532 ,  A61B5/7221 ,  G01M99/008 ,  G01N33/49 ,  G01N33/66 ,  G16C20/80 ,  G16C99/00 ,  A61B2560/028 ,  A61B2560/0223 ,  A61B2560/0266 ,  A61B2560/0276

Abstract: Systems and methods for processing sensor data and end of life detection are provided. In some embodiments, a method for determining the end of life of a continuous analyte sensor includes evaluating a plurality of risk factors using an end of life function to determine an end of life status of the sensor and providing an output related to the end of life status of the sensor. The plurality of risk factors may be selected from the list including the number of days the sensor has been in use, whether there has been a decrease in signal sensitivity, whether there is a predetermined noise pattern, whether there is a predetermined oxygen concentration pattern, and error between reference BG values and EGV sensor values.