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公开(公告)号：US09203425B2
公开(公告)日：2015-12-01
申请号：US14662343
申请日：2015-03-19
Applicant: Ramot at Tel-Aviv University Ltd.
Inventor： Yossef Ehrlichman , Ofer Amrani , Shlomo Ruschin
IPC: H03M1/00 , H03M1/70 , G02F1/01 , G02F7/00 , H04B10/2575 , H04B10/516 , G02F1/225 , H04B10/556 , H04B10/54 , H04B10/50 , G02F1/015 , G02F1/21
CPC classification number: H04B10/516 , G02F1/0121 , G02F1/015 , G02F1/225 , G02F7/00 , G02F2001/212 , G02F2203/19 , H03M1/002 , H03M1/70 , H04B10/2504 , H04B10/2575 , H04B10/505 , H04B10/5055 , H04B10/541 , H04B10/556
Abstract: A modulator device for converting digital data into modulation of an optical signal includes an electronic input for receiving an input data word of N bits and an electrically controllable modulator for modulating the intensity of an optical signal, the modulator including M actuating electrodes where M≧N. An electrode actuating device, most preferably a digital-to-digital convertor, operates actuating electrodes so that at least one electrode is actuated as a function of values of more than one bit of the input data word. According to an alternative, or supplementary, aspect of the invention, the set of electrodes includes at least one electrode having an effective area which is not interrelated to others of the set by factors of two. In one preferred implementation, a Mach-Zehnder modulator also provides phase modulation to give QAM functionality. Another implementation employs a semiconductor laser.
Abstract translation: 用于将数字数据转换为光信号调制的调制器装置包括用于接收N位输入数据字的电子输入端和用于调制光信号强度的电可控调制器，该调制器包括M个致动电极，其中M≥N 。 电极致动装置，最优选数字 - 数字转换器，操作致动电极，使得至少一个电极作为输入数据字的多于一位的值的函数被致动。 根据本发明的替代或补充方面，所述电极组包括至少一个电极，所述至少一个电极具有与所述组中的其它因素不相关的有效面积。 在一个优选实施例中，马赫 - 曾德调制器还提供相位调制以提供QAM功能。 另一个实施方案采用半导体激光器。
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公开(公告)号：US09193813B2
公开(公告)日：2015-11-24
申请号：US14565307
申请日：2014-12-09
Inventor： Moshe Kol , Matthew W. Holtcamp , Konstantin Press , Ayellet Stopper
IPC: C08F110/06 , C07F7/28 , C07F7/00 , C08F4/64 , C08F4/60
CPC classification number: C08F110/06 , C07F7/00 , C07F7/003 , C07F7/28 , C08F4/60189 , C08F4/64189 , C08F4/659 , C08F2500/03 , C08F2500/15 , C08F2500/02 , C08F2500/04
Abstract: A phenylene-bridged Salalen catalyst, a catalyst system comprising an activator and the phenylene-bridged Salalen catalyst, a process comprising contacting one or more olefins with the catalyst system, and polymers produced by the process are disclosed herein.
Abstract translation: 亚苯基桥接的Salalen催化剂，包含活化剂和亚苯基桥接的Salalen催化剂的催化剂体系，包括使一种或多种烯烃与催化剂体系接触的方法，以及通过该方法生产的聚合物。
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公开(公告)号：US20150331992A1
公开(公告)日：2015-11-19
申请号：US14712256
申请日：2015-05-14
Applicant: Ramot at Tel-Aviv University Ltd.
Inventor： Livnat ARNON JERBY , Eytan RUPPIN
IPC: G06F19/18 , A61K31/55 , A61K31/343 , A61K31/137 , A61K31/277 , A61K31/4025 , A61K31/4409
CPC classification number: A61K31/137 , A61K31/135 , A61K31/277 , A61K31/343 , A61K31/4025 , A61K31/4406 , A61K31/55 , G16B5/00 , G16B20/00
Abstract: Systems and methods for identifying synthetic lethal (SL) and synthetic dosage lethal (SDL) interactions and networks are provided. Further provided are methods for predicting cancer gene essentiality, drug efficacy and survival of cancer patients using data-driven identification of synthetic lethality in cancer are provided. Novel drug candidates and drug combinations for use in cancer therapy and method for prioritizing existing cancer therapies are also provided.
Abstract translation: 提供了用于识别合成致死（SL）和合成剂量致死（SDL）相互作用和网络的系统和方法。 还提供了使用数据驱动的癌症中合成致死性鉴定来预测癌症基因必需性，药物功效和癌症患者生存的方法。 还提供了用于癌症治疗的新型药物候选物和药物组合以及用于优先化现有癌症疗法的方法。
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公开(公告)号：US20150297099A1
公开(公告)日：2015-10-22
申请号：US14433055
申请日：2013-10-03
Applicant: Ramot at Tel-Aviv University Ltd.
Inventor： Shimon ARAD (ABBOUD) , Muhammad MAHAJNA , Keren HORMAN
IPC: A61B5/029 , A61B5/0205 , A61B5/00
CPC classification number: A61B5/029 , A61B5/02028 , A61B5/0205 , A61B5/0295 , A61B5/0536 , A61B5/08 , A61B5/1073 , A61B5/4878 , A61B5/686 , A61B5/6869 , A61B5/7278 , G16H50/50
Abstract: A method for determining values of a set of one or more geometric parameters of a patient's heart, the method comprising: a) making impedance measurements of the patient's chest, at least some of the measurements using internal electrodes; and b) finding values of the set of parameters that provide a good fit to results of the impedance measurements.
Abstract translation: 一种用于确定患者心脏的一个或多个几何参数的集合的值的方法，所述方法包括：a）使用内部电极进行所述患者胸部的阻抗测量，至少一些测量; 以及b）找到提供与阻抗测量结果良好匹配的参数集合的值。
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公开(公告)号：US20150259392A1
公开(公告)日：2015-09-17
申请号：US14433047
申请日：2013-03-05
Applicant: RAMOT AT TEL-AVIV UNIVERSITY LTD.
Inventor： Daniel Offen , Israel Aharony
IPC: C07K14/47
CPC classification number: C07K14/47 , A61K38/00 , C07K14/4703 , C07K14/8139 , C07K2319/10
Abstract: An isolated peptide comprising a Huntingtin (Htt) amino acid sequence being no longer than 15 amino acids, wherein said Htt amino acid sequence comprises the sequence X1X2X3X4 X5, wherein X1 is a hydrophobic amino acid or threonine, X2 is a hydrophobic amino acid, X3 is a hydrophobic amino acid, X4 is an acidic amino acid and X5 is selected from the group consisting of glycine, serine and alanine, the peptide capable of specifically inhibiting the activity of caspase 6.
Abstract translation: 一种分离的肽，其包含不超过15个氨基酸的亨廷丁（Htt）氨基酸序列，其中所述Htt氨基酸序列包含序列X1X2X3X4X5，其中X1是疏水性氨基酸或苏氨酸，X2是疏水性氨基酸，X3 是疏水性氨基酸，X4是酸性氨基酸，X5选自甘氨酸，丝氨酸和丙氨酸，能够特异性抑制胱天蛋白酶6活性的肽。
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Patent Agency Ranking
公开(公告)号：US20150256735A1
公开(公告)日：2015-09-10
申请号：US14718189
申请日：2015-05-21
Applicant: Ramot at Tel-Aviv University Ltd.
Inventor： Yuval BARKAN , Hedva SPITZER , Yael FALTIN GEFEN
CPC classification number: H04N5/2355 , G06K9/4661 , G06T3/40 , G06T5/50 , G06T9/00 , G06T2207/20016 , G06T2207/20208 , H04N5/265
Abstract: A method of processing an image is disclosed. The method comprises obtaining an image decomposed into a set of scaled images, each being characterized by a different image-scale; and calculating, for each of at least some scaled images, a relative luminance between the scaled image and another scaled image of the set, using intensities in the scaled image and intensities in the another scaled image. The method further comprises processing each scaled image using an adaptation procedure featuring an image-specific effective saturation function of the relative luminance, thereby providing a processed scaled image; combining at least some of the processed scaled images to provide a combined image; and outputting the combined image to a computer readable medium.
Abstract translation: 公开了处理图像的方法。 该方法包括获得分解为一组缩放图像的图像，每个图像的特征在于不同的图像尺度; 以及对于至少一些缩放图像中的每一个，使用所述缩放图像中的强度和所述另一缩放图像中的强度来计算所述缩放图像与所述组的另一缩放图像之间的相对亮度。 该方法还包括使用特征为相对亮度的图像特定有效饱和度函数的适应过程来处理每个缩放图像，从而提供经处理的缩放图像; 组合至少一些经处理的缩放图像以提供组合图像; 并将组合的图像输出到计算机可读介质。
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公开(公告)号：US20150202348A1
公开(公告)日：2015-07-23
申请号：US14581540
申请日：2014-12-23
Applicant: Ramot at Tel-Aviv University Ltd.
Inventor： Tal DVIR , Dan PEER , Michal SHEVACH , Neta SOFFER TSUR
CPC classification number: A61L27/3633 , A61K35/34 , A61K35/44 , A61L27/14 , A61L27/3604 , A61L27/3687 , A61L27/3804 , A61L27/3826 , A61L27/3834 , A61L27/52 , A61L27/58 , A61L2430/20 , A61L2430/40 , C12N5/0657 , C12N5/0691 , C12N5/0696
Abstract: Compositions of matter comprising decellularized omentum are disclosed. The compositions may be scaffolds, hydrogels or hydrogel precursor compositions. Methods of generating the compositions are disclosed as well as uses thereof.
Abstract translation: 公开了包含脱细胞网膜的物质组合物。 组合物可以是支架，水凝胶或水凝胶前体组合物。 公开了生成组合物的方法及其用途。
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公开(公告)号：US20150166667A1
公开(公告)日：2015-06-18
申请号：US14521494
申请日：2014-10-23
Applicant: RAMOT AT TEL-AVIV UNIVERSITY LTD.
Inventor： Efrat WERTHEIMER
IPC: C07K16/28 , C12N15/113 , A61K38/00 , C07K16/18
CPC classification number: C07K16/2869 , A61K9/0014 , A61K31/713 , A61K38/00 , A61K38/1796 , C07K2317/76 , C12N15/1138 , C12N2310/14 , C12N2310/531
Abstract: The present invention generally concerns methods and compositions for treating skin hyperplasia and cancer.
Abstract translation: 本发明一般涉及用于治疗皮肤增生和癌症的方法和组合物。
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公开(公告)号：US09058736B2
公开(公告)日：2015-06-16
申请号：US14040763
申请日：2013-09-30
Applicant: Ramot at Tel-Aviv University Ltd. , Ben-Gurion University of the Negev Research and Development Authority
Inventor： Israel Gannot , Dimitry Litvak , Yaniv Zigel
CPC classification number: G08B21/0438 , A61B5/1117 , A61B5/7267 , A61B2503/08 , A61B2562/0204 , A61B2562/0219 , G06F19/00 , G08B21/043 , G08B21/0446 , G08B29/183
Abstract: Apparatus for detection of human falls comprises: an acceleration detector, for detecting vibration events, typically placed on a floor, a microphone, located in association with the acceleration detector for detection of corresponding sound events, and a classification unit to classify concurrent events from the microphone and the acceleration detector, thereby to determine whether a human fall is indicated. If the event appears to be a human fall, then an alarm is raised.
Abstract translation: 用于检测人类跌倒的装置包括：用于检测通常放置在地板上的振动事件的加速度检测器，与加速度检测器相关联的麦克风，用于检测相应的声音事件;以及分类单元，用于对来自 麦克风和加速度检测器，从而确定是否指示人的跌倒。 如果事件似乎是人为的跌倒，则会发出警报。
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370.发明申请公开(公告)号：US20150158958A1
公开(公告)日：2015-06-11
申请号：US14406414
申请日：2013-08-02
Inventor： Bruce A. Harrington , Garth R. Giesbrecht , Matthew W. Holtcamp , Moshe Kol , Konstantin Press , Gregory S. Day
IPC: C08F10/14
CPC classification number: C08F10/00 , C08F4/64189 , C08F110/14 , C08F210/14 , C10G50/00 , C10M107/10
Abstract: Polyalphaolefins and Salan catalysts, catalyst systems, and processes to produce the polyalphaolefins. Also disclosed are high-viscosity index polyalphaolefins and processes for producing them.
Abstract translation: 聚α-烯烃和Salan催化剂，催化剂体系和生产聚α-烯烃的方法。 还公开了高粘度指数聚α-烯烃及其制备方法。
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