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31.发明公开公开(公告)号：US20240110915A1
公开(公告)日：2024-04-04
申请号：US18253153
申请日：2021-11-16
Applicant: University of South Australia , Central Adelaide Local Health Inc , The University of Adelaide
IPC: G01N33/574 , C12Q1/6886 , G01N15/14
CPC classification number: G01N33/57407 , C12Q1/6886 , G01N15/14 , G01N33/57492 , C12Q2600/118 , C12Q2600/158 , G01N2015/1006
Abstract: The present disclosure relates to methods, products and systems for the prognosis of subjects suffering from multiple myeloma. In certain embodiments, the present disclosure provides a method of prognosis for a subject suffering from multiple myeloma. The method comprises determining the level of desmoglein 2 (DSG2) in malignant plasma cells from the subject, wherein an increased level of DSG2 in the plasma cells is indicative of a poorer prognosis for the subject.
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公开(公告)号：US20230301930A1
公开(公告)日：2023-09-28
申请号：US18114409
申请日：2023-02-27
Applicant: UNIVERSITY OF SOUTH AUSTRALIA
Inventor： Ivan Mark KEMPSON , Tyron James TURNBULL
CPC classification number: A61K9/5123 , A61K33/242 , A61K41/0038 , A61P35/00 , B82Y5/00 , B82Y40/00
Abstract: Methods of potentiating chemotherapy or radiotherapy are disclosed. The methods comprise administering to a subject in need of chemotherapeutic or radiotherapeutic treatment an effective amount of a composition comprising biocompatible nanoparticles under conditions in which the nanoparticles alter one or more cell regulatory mechanisms in cells in which the nanoparticles are localised or other cells. Then one or more doses of a chemotherapeutic or radiotherapeutic treatment are administered to the subject either concurrently with or after the nanoparticles have altered the one or more cell regulatory mechanisms in the cells in which the nanoparticles are localised or other cells. Also disclosed are methods of enhancing the effects of chemotherapy or radiotherapy on a cell population, methods of increasing the amount of strand breaks in DNA in a cell, and methods of inducing cancer cell death.
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公开(公告)号：US11445729B2
公开(公告)日：2022-09-20
申请号：US16541834
申请日：2019-08-15
Applicant: The Flinders University of South Australia
Abstract: The present invention relates to methods for enhancing at least one growth parameter of a leguminous plant via co-inoculation of a leguminous plant with at least one rhizobial microorganism together with at least one actinobacterial microorganism. In further aspects, the present invention also relates to leguminous plants co-inoculated with at least one rhizobial microorganism together with at least one actinobacterial microorganism, as well as specific actinobacterial strains and inoculant compositions which are useful in accordance with the present invention.
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公开(公告)号：US11425912B2
公开(公告)日：2022-08-30
申请号：US16539696
申请日：2019-08-13
Applicant: The Flinders University of South Australia
Abstract: The present invention relates to methods for enhancing at least one growth parameter of a leguminous plant via co-inoculation of a leguminous plant with at least one rhizobial microorganism together with at least one actinobacterial microorganism. In further aspects, the present invention also relates to leguminous plants co-inoculated with at least one rhizobial microorganism together with at least one actinobacterial microorganism, as well as specific actinobacterial strains and inoculant compositions which are useful in accordance with the present invention.
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公开(公告)号：US11226304B2
公开(公告)日：2022-01-18
申请号：US16340442
申请日：2017-10-13
Applicant: University of South Australia , Sentek Pty Ltd
Inventor： Drew Raymond Evans , Sam Rudd , Peter Buss , Michael Reginald Dalton , Michael Robert Portmann
Abstract: An apparatus for selectively detecting an anion in a medium and/or selectively measuring the concentration of an anion in a medium. The apparatus comprises at least one sensor and a conductive polymer film and is configured such that dielectric and/or electric property changes of the conductive polymer film can be detected by the sensor when the conductive polymer film is in hydraulic contact with the medium or after it has been in hydraulic contact with the medium. Methods of selectively detecting an anion in a medium and/or selectively determining a concentration of an anion in a medium are also provided.
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Patent Agency Ranking
公开(公告)号：US20200281964A1
公开(公告)日：2020-09-10
申请号：US16788909
申请日：2020-02-12
Applicant: Balakrishnan Siddartha Ramakrishna , Yale University , Flinders University of South Australia
Inventor： Balakrishnan Siddartha Ramakrishna , Graeme Paul Young , Ian Lewis Brown , Henry Joseph Binder
IPC: A61K33/00 , A23L2/38 , A61K31/718 , A61K33/14 , A61K47/36 , A61K9/00 , A23L2/52 , A61K33/30 , A61K33/34 , A61K33/06 , A23L33/105 , A23L33/16 , A23L29/212 , A23L33/10 , A23L33/21 , A23L29/269 , A23L29/238 , A23L29/256 , A23L29/231 , A23L29/25 , A23L29/281 , A61K31/194 , A61K31/7004
Abstract: Provided herein are compositions, for example: oral rehydration compositions, beverages, food items, methods and uses, which utilise resistant starch to prevent or treat dehydration, including dehydration which is caused by diarrhoea. Beverages, food items and oral rehydration solutions including a resistant starch, which are suitable for aiding in the maintenance and restoration of hydration levels in individuals undertaking physical activities, including sports, are also disclosed.
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公开(公告)号：US20200261887A1
公开(公告)日：2020-08-20
申请号：US16634565
申请日：2018-07-25
Applicant: University of South Australia
Inventor： Hans-Jürgen Wirth , Neeraj Verma
IPC: B01J20/286 , C12M1/00 , B01J20/26 , B01J20/28 , B01J20/32
Abstract: A solid phase microextraction substrate is disclosed. The solid phase microextraction substrate has a sorbent coating on at least part of a surface thereof. The coating is adapted for extracting at least one analyte component from a fluid matrix. The coating includes sorbent particles in a polymeric adhesive matrix. A majority of pores in each sorbent particle in the coating do not contain substantially any of the polymeric adhesive matrices.
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公开(公告)号：US20200216494A1
公开(公告)日：2020-07-09
申请号：US16624367
申请日：2018-06-29
Applicant: ROYAL MELBOURNE INSTITUTE OF TECHNOLOGY , UNIVERSITY OF SOUTH AUSTRALIA , THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY AND , MONASH UNIVERSITY
Inventor： Stavros SELEMIDIS , Doug A. BROOKS , John O'LEARY
Abstract: The present invention relates generally to the field of immunomodulation. Taught herein is an agent for inhibiting immunostimulation mediated by a Toll-like receptor useful in the treatment of viral and microbial pathogenesis, diseases involving elements of autoimmunity and inflammation as well as cancer. The agent antagonizes disulfide bond formation between C98 and C475 of Toll-like receptor 7 (TLR7) thereby preventing TLR7 activation. Pharmaceutical compositions are also enabled herein.
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公开(公告)号：US20200037528A1
公开(公告)日：2020-02-06
申请号：US16541834
申请日：2019-08-15
Applicant: The Flinders University of South Australia
Abstract: The present invention relates to methods for enhancing at least one growth parameter of a leguminous plant via co-inoculation of a leguminous plant with at least one rhizobial microorganism together with at least one actinobacterial microorganism. In further aspects, the present invention also relates to leguminous plants co-inoculated with at least one rhizobial microorganism together with at least one actinobacterial microorganism, as well as specific actinobacterial strains and inoculant compositions which are useful in accordance with the present invention.
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公开(公告)号：US20180252713A1
公开(公告)日：2018-09-06
申请号：US15754797
申请日：2016-08-24
Inventor： Gregory A. Weiss , Joshua Britton , Colin L. Raston
IPC: G01N33/573 , C12N9/14
CPC classification number: G01N33/573 , C07K1/22 , C12N9/14 , C12N9/96 , C12N11/00 , C12N13/00 , C12Y301/03001 , C12Y301/04001 , C12Y302/01023 , G01N31/10 , G01N2203/0055 , G01N2400/00
Abstract: There are provided, inter alia, methods for reacting an enzyme and its substrate, methods for purifying a protein and an enzyme reactor and its use thereof.
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