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31.发明申请ACTUATED MICROFLUIDIC STRUCTURES FOR DIRECTED FLOW IN A MICROFLUIDIC DEVICE AND METHODS OF USE THEREOF 审中-公开微流控器件中导向流动的微流化微结构及其使用方法公开(公告)号：US20160158757A1
公开(公告)日：2016-06-09
申请号：US14961868
申请日：2015-12-07
Applicant: Berkeley Lights, Inc.
Inventor： Keith J. Breinlinger , Andrew W. McFarland , J. Tanner Nevill
IPC: B01L3/00
CPC classification number: B01L3/502761 , B01L3/502715 , B01L3/50273 , B01L2200/0647 , B01L2300/041 , B01L2300/0816 , B01L2300/0864 , B01L2300/0877 , B01L2300/0883 , B01L2300/0887 , B01L2300/12 , B01L2400/0475 , B01L2400/0481
Abstract: A microfluidic device can comprise a plurality of interconnected microfluidic elements. A plurality of actuators can be positioned abutting, immediately adjacent to, and/or attached to deformable surfaces of the microfluidic elements. The actuators can be selectively actuated and de-actuated to create directed flows of a fluidic medium in the microfluidic (or nanofluidic) device. Further, the actuators can be selectively actuated and de-actuated to create localized flows of a fluidic medium in the microfluidic device to move reagents and/or micro-objects in the microfluidic device.
Abstract translation: 微流体装置可以包括多个互连的微流体元件。 多个致动器可以被定位成邻接于微流体元件的可变形表面并且/或附接到微流体元件的可变形表面。 可以选择性地致动致动器并致动以在微流体（或纳流体）装置中产生流体介质的定向流。 此外，可以选择性地致动致动器并致动以在微流体装置中产生流体介质的局部流动，以移动微流体装置中的试剂和/或微物体。
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公开(公告)号：USD996465S1
公开(公告)日：2023-08-22
申请号：US29867347
申请日：2022-10-20
Applicant: Berkeley Lights, Inc.
Designer： Pavan Ramkumar , Michael J. Stone , Keith J. Breinlinger
Abstract: FIG. 1 is a front view of a first embodiment of a display screen with graphical user interface showing our new design; and,
FIG. 2 is a front view of a second embodiment of a display screen with graphical user interface.
The broken lines in FIGS. 1 and 2 show a display screen and form no part of the claimed design.-
33.发明授权公开(公告)号：US10829728B2
公开(公告)日：2020-11-10
申请号：US16010176
申请日：2018-06-15
Applicant: Berkeley Lights, Inc.
Inventor： Volker L. S. Kurz , Troy A. Lionberger , Eric K. Sackmann , Kai W. Szeto , Paul M. Lebel , Brandon R. Bruhn , Keith J. Breinlinger , Eric D. Hobbs , Andrew W. McFarland , J. Tanner Nevill , Xiaohua Wang
Abstract: Apparatuses and methods are described for the use of optically driven bubble, convective and displacing fluidic flow to provide motive force in microfluidic devices. Alternative motive modalities are useful to selectively dislodge and displace micro-objects, including biological cells, from a variety of locations within the enclosure of a microfluidic device.
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公开(公告)号：US10723988B2
公开(公告)日：2020-07-28
申请号：US15135707
申请日：2016-04-22
Applicant: Berkeley Lights, Inc.
Inventor： Randall D. Lowe, Jr. , Kristin Beaumont , Aathavan Karunakaran , Natalie Marks , Jason M. McEwen , Mark P. White , J. Tanner Nevill , Gang F. Wang , Andrew W. McFarland , Daniele Malleo , Keith J. Breinlinger , Xiao Guan , Kevin T. Chapman
Abstract: Systems, methods and kits are described for culturing one or more biological cells in a microfluidic device, including provision of nutrients and gaseous components configured to enhance cell growth, viability, portability, or any combination thereof. In some embodiments, culturing a single cell may produce a clonal population in the microfluidic device.
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公开(公告)号：US20200038857A1
公开(公告)日：2020-02-06
申请号：US16513445
申请日：2019-07-16
Applicant: Berkeley Lights, Inc.
Inventor： Andrew W. McFarland , Daniele Malleo , J. Tanner Nevill , Russell A. Newstrom , Keith J. Breinlinger , Paul M. Lundquist , Justin K. Valley , Jonathan Cloud Dragon Hubbard
Abstract: A system for operating an electrokinetic device includes a support configured to hold and operatively couple with the electrokinetic device, an integrated electrical signal generation subsystem configured to apply a biasing voltage across a pair of electrodes in the electrokinetic device, and a light modulating subsystem configured to emit structured light onto the electrokinetic device. The system can further include a thermally controlled flow controller, and/or be configured to measure impedance across the electrokinetic device. The system can be a light microscope, including an optical train. The system can further include a light pipe, which can be part of the light modulating system, and which can be configured to supply light of substantially uniform intensity to the light modulating system or directly to the optical train.
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Patent Agency Ranking
公开(公告)号：USD844471S1
公开(公告)日：2019-04-02
申请号：US29609549
申请日：2017-06-30
Applicant: Berkeley Lights, Inc.
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37.发明申请公开(公告)号：US20190083983A1
公开(公告)日：2019-03-21
申请号：US16057306
申请日：2018-08-07
Applicant: Berkeley Lights, Inc.
Inventor： Keith J. Breinlinger , Andrew W. McFarland , J. Tanner Nevill
IPC: B01L3/00
Abstract: A microfluidic device can comprise a plurality of interconnected microfluidic elements. A plurality of actuators can be positioned abutting, immediately adjacent to, and/or attached to deformable surfaces of the microfluidic elements. The actuators can be selectively actuated and de-actuated to create directed flows of a fluidic medium in the microfluidic (or nanofluidic) device. Further, the actuators can be selectively actuated and de-actuated to create localized flows of a fluidic medium in the microfluidic device to move reagents and/or micro-objects in the microfluidic device.
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38.发明申请公开(公告)号：US20190060900A1
公开(公告)日：2019-02-28
申请号：US16033811
申请日：2018-07-12
Applicant: Berkeley Lights, Inc.
Inventor： Keith J. Breinlinger , Andrew W. McFarland , J. Tanner Nevill
IPC: B01L3/00
Abstract: A microfluidic device can comprise a plurality of interconnected microfluidic elements. A plurality of actuators can be positioned abutting, immediately adjacent to, and/or attached to deformable surfaces of the microfluidic elements. The actuators can be selectively actuated and de-actuated to create directed flows of a fluidic medium in the microfluidic (or nanofluidic) device. Further, the actuators can be selectively actuated and de-actuated to create localized flows of a fluidic medium in the microfluidic device to move reagents and/or micro-objects in the microfluidic device.
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39.发明授权公开(公告)号：US10058865B2
公开(公告)日：2018-08-28
申请号：US14961868
申请日：2015-12-07
Applicant: Berkeley Lights, Inc.
Inventor： Keith J. Breinlinger , Andrew W. McFarland , J. Tanner Nevill
IPC: B01L3/00
CPC classification number: B01L3/502761 , B01L3/502715 , B01L3/50273 , B01L2200/0647 , B01L2300/041 , B01L2300/0816 , B01L2300/0864 , B01L2300/0877 , B01L2300/0883 , B01L2300/0887 , B01L2300/12 , B01L2400/0475 , B01L2400/0481
Abstract: A microfluidic device can comprise a plurality of interconnected microfluidic elements. A plurality of actuators can be positioned abutting, immediately adjacent to, and/or attached to deformable surfaces of the microfluidic elements. The actuators can be selectively actuated and de-actuated to create directed flows of a fluidic medium in the microfluidic (or nanofluidic) device. Further, the actuators can be selectively actuated and de-actuated to create localized flows of a fluidic medium in the microfluidic device to move reagents and/or micro-objects in the microfluidic device.
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公开(公告)号：US20180099282A1
公开(公告)日：2018-04-12
申请号：US15659855
申请日：2017-07-26
Applicant: Berkeley Lights, Inc.
Inventor： Keith J. Breinlinger , Eric D. Hobbs , Daniele Malleo , J. Tanner Nevill , Mark P. White
CPC classification number: B01L3/502761 , B01L3/502715 , B01L3/50273 , B01L2200/0668 , B01L2300/0816 , B01L2300/0819 , B01L2300/0848 , B01L2300/0877 , B01L2400/0424 , B01L2400/0427 , B01L2400/0454 , B01L2400/0457 , B01L2400/086 , G01N1/4077 , G01N2001/4083
Abstract: A microfluidic apparatus is provided having one or more sequestration pens configured to isolate one or more target micro-objects by changing the orientation of the microfluidic apparatus with respect to a globally active force, such as gravity. Methods of selectively directing the movements of micro-objects in such a microfluidic apparatus using gravitational forces are also provided. The micro-objects can be biological micro-objects, such as cells, or inanimate micro-objects, such as beads.
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