公开(公告)号：US10241066B2

公开(公告)日：2019-03-26

申请号：US15112639

申请日：2014-01-30

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Nicholas Matthew Cooper McGuinness ,  Melinda M. Valencia ,  Manish Giri ,  Chantelle Elizabeth Domingue ,  Jeremy Sells ,  Matthew David Smith

IPC: G01N27/06 ,  G01N15/02 ,  G01N27/12 ,  B01L3/00 ,  G01N15/12 ,  G01N15/10 ,  G01N15/14

Abstract: A microfluidic sensing device comprises a channel and an impedance sensor within the channel. The impedance sensor comprises a local ground and an electrode within the channel. The local ground and the electrode are to form an electric field region that is elongated along the channel.

公开(公告)号：US20180326728A1

公开(公告)日：2018-11-15

申请号：US15772344

申请日：2016-02-05

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Garrett E. Clark ,  Michael W. Cumbie ,  Jeremy Sells ,  Mark H. MacKenzie

IPC: B41J2/155 ,  B41J2/14 ,  B41J29/393

CPC classification number: B41J2/155 ,  B41J2/14153 ,  B41J2/14201 ,  B41J2/2135 ,  B41J2/2146 ,  B41J11/007 ,  B41J11/0095 ,  B41J13/32 ,  B41J29/38 ,  B41J29/393 ,  B41J2202/20

Abstract: The present disclosure includes a description of an example print bar that includes an ejection die disposed on a support element, and a sensor disposed at a particular location on the support element.

公开(公告)号：US20180021778A1

公开(公告)日：2018-01-25

申请号：US15547756

申请日：2015-01-30

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Jeremy Sells ,  Chantelle E. Domingue ,  Robert Moline ,  Manish Giri

IPC: B01L3/00

CPC classification number: B01L3/502723 ,  B01L2200/0684 ,  B01L2200/10 ,  B01L2300/0681 ,  B01L2300/0816 ,  B01L2400/0439 ,  B01L2400/0442 ,  C12M23/16 ,  C12M29/20 ,  C12M41/48 ,  G01N33/48707

Abstract: Vented microfluidic reservoirs can include a housing and a vent coupled to the housing to vent air associated with a fluid sample communicated into the housing to an environment surrounding a microfluidic device coupled to the housing.

公开(公告)号：US20180015457A1

公开(公告)日：2018-01-18

申请号：US15546735

申请日：2015-01-30

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Nicholas McGuinness ,  Chantelle Domingue ,  Manish Giri ,  Jeremy Sells

IPC: B01L3/00

CPC classification number: B01L3/50273 ,  B01L3/502715 ,  B01L2200/10 ,  B01L2300/023 ,  B01L2300/024 ,  B01L2300/027 ,  B01L2300/0627 ,  B01L2300/0816 ,  B01L2300/088 ,  B01L2300/0883 ,  B01L2300/1827 ,  B01L2400/0442 ,  B01L2400/0487 ,  B01L2400/086 ,  G01N27/07 ,  G01N33/48785

Abstract: A microfluidic diagnostic device may comprise a fluid inlet to receive a fluid from a fluidic slot, a main microfluidic channel fluidly coupled to the fluid inlet, and a main microfluidic pump interposed between the fluid inlet and the main microfluidic channel to continuously circulate a fluid through the fluidic slot, fluid inlet, and main microfluidic channel wherein the width of the fluid inlet is different from the width of the main microfluidic channel. A diagnostic device, comprising a fluidic slot, a fluid inlet fluidly coupled to the fluidic slot, a main channel fluidly coupled to the fluid inlet, and an inlet pump interposed between the fluid inlet and channel wherein the cross-sectional area of the fluid inlet is relatively larger at least one point than the cross-sectional area of the channel.

公开(公告)号：US20180003611A1

公开(公告)日：2018-01-04

申请号：US15546342

申请日：2015-01-30

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Jeremy Sells ,  Nick McGuinness ,  Chantelle Domingue ,  Manish Giri

IPC: G01N15/10 ,  B01L3/00

CPC classification number: G01N15/1056 ,  B01L3/502715 ,  B01L3/502761 ,  B01L2200/0647 ,  B01L2300/0627 ,  B01L2300/0645 ,  B01L2300/0681 ,  B01L2300/0816 ,  B01L2300/087 ,  B01L2400/0439 ,  B01L2400/0442 ,  G01N15/1031 ,  G01N2015/1006 ,  G01N2015/1062

Abstract: A device including a microfluidic channel structure formed on a substrate and including a first channel and a fluid actuator within the microfluidic channel structure. A sense region within the first channel is to receive a fluid flow of target biologic particles for counting in a single file pattern, with the sense region having a volume on a same order of magnitude as a volume of a single one of the target biologic particles.

公开(公告)号：US20170368549A1

公开(公告)日：2017-12-28

申请号：US15546511

申请日：2015-01-30

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Manish Giri ,  Chantelle Elizabeth Domingue ,  Nicholas Matthew Cooper McGuinness ,  Jeremy Sells ,  Sirena Lu ,  Melinda M. Valencia

IPC: B01L3/00 ,  G01N33/543

CPC classification number: B01L3/502753 ,  B01L3/5027 ,  B01L3/502715 ,  B01L3/50273 ,  B01L2200/0647 ,  B01L2200/0668 ,  B01L2200/10 ,  B01L2200/141 ,  B01L2200/143 ,  B01L2300/023 ,  B01L2300/024 ,  B01L2300/027 ,  B01L2300/0636 ,  B01L2300/0663 ,  B01L2300/088 ,  B01L2300/1827 ,  B01L2400/046 ,  C12Q1/005 ,  C12Q1/6804 ,  G01N15/0656 ,  G01N33/54373 ,  G01N33/5438 ,  G01N2015/0065 ,  G01N2015/0687 ,  C12Q2531/113 ,  C12Q2531/143 ,  C12Q2563/131 ,  C12Q2565/607 ,  C12Q2565/629

Abstract: A microfluidic diagnostic chip may comprise a microfluidic channel, a functionalizable enzymatic sensor in the microfluidic channel, the functionalizable enzymatic sensor comprising a binding surface to bind with a biomarker in a fluid, and a microfluidic pump to pass the fluid over the binding surface. A microfluidic device may comprise a number of pumps to pump a fluid though the number of microfluidic channels and a number of microfluidic channels comprising at least one sensor to detect a change in a chemical characteristic of the fluid in response to presence of the fluid on the sensor

公开(公告)号：US20170328882A1

公开(公告)日：2017-11-16

申请号：US15522831

申请日：2015-01-30

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Melinda M Valencia ,  Chantelle E Domingue ,  Jeremy Sells ,  Manish Giri ,  Sadiq Bengali

IPC: G01N33/49 ,  B01L3/00 ,  G01N27/02 ,  B81B1/00

Abstract: Example implementations relate to coagulation sensing. For example, a microfluidic chip for coagulation sensing may include a microfluidic channel, an outlet at an end of the microfluidic channel having an air interface, and an impedance sensor located within the microfluidic channel and within a particular proximity to the air interface, the impedance sensor to determine a stage of a coagulation cascade of a blood sample flowing through the microfluidic channel to the impedance sensor.