摘要:
The present invention relates to An N-acetylglucosamine derivative represented by the following formula (1), and a hyaluronic acid production promoting agent containing the same and a skin external preparation containing the same: wherein R1 is a hydrogen atom or an alkyl group having 2 to 18 carbon atoms; R2, R3, and R4 are hydrogen atoms or acyl groups having 2 to 18 carbon atoms and may be all the same or different from others; the steric structure at position 1 may be α or β; provided that R1, R2, R3, and R4 must not be all hydrogen atoms. It is intended to provide an easily available hyaluronic acid production promoting agent and a skin external preparation whereby the production of hyaluronic acid can be promoted in the skin and thus the skin can be maintained in a vital and moist state so that it is expected that the human skin can be prevented from age.
摘要:
The external skin care composition of the present invention comprises N-acetylglucosamine and at least one member selected from the group consisting of retinoid and pro-vitamin A. The external skin care composition of the present invention has an effect of promoting the production of epidermal hyaluronic acid and can retain firmness and moisture of the skin.
摘要:
This invention relates to a collagen metabolism ameliorant containing N-methyl-L-serine as an active ingredient, more particularly, a collagen metabolism ameliorant efficacious against collagen hypometabolism caused by aging or diseases accompanied with an abnormal cumulation of collagen, such as hepatic and pulmonary fibroses, keloid, hypertrophic scar, scleroderma, fibrosis in the scalp, or the like.
摘要:
The present invention is directed to KIAA1199, which is a novel factor involved in decomposition of hyaluronic acid, and to use thereof. More specifically, the invention is directed to a hyaluronic acid decomposition-promoting agent containing the KIAA1199 gene and a protein encoded by the gene; to a hyaluronic acid decomposition-inhibiting agent characterized by inhibiting the activity or expression thereof (including an siRNA or a monoclonal antibody); and to a method for screening a novel hyaluronic acid decomposition-controlling agent, in which the method contains employing the expression of KIAA1199 as an index.
摘要:
This storage apparatus for providing a dynamically expandable virtual volume to a host system to access the virtual volume comprises an allocation unit for configuring a group with a plurality of disks for providing a storage area to be allocated to the virtual volume, and allocating the storage area respectively from a plurality of the groups to the virtual volume; and a storage area arrangement unit for rearranging the storage area in each of the groups being used by the virtual volume to become optimal among each of the groups based on external operation.
摘要:
The purpose of the present invention is to reduce the amounts of nitrate nitrogen and ammonia, which can be absorbed through the digestive tract and are factors for causing mastitis in livestock animals, thereby reducing the incidence rate of mastitis. A composition for preventing and treating mastitis for livestock animals comprises a rock powder containing silicic acid and aluminum oxide as active ingredients. When the composition is mixed with feed and the feed is given to livestock animals, nitrogen compounds including ammonia nitrogen and nitrate nitrogen generated in the body of the livestock animals can be chemically adsorbed by aluminum oxide and silicic acid, whereby the over-absorption of the nitrogen compounds through the digestive tract can be suppressed. At the same time, minor elements contained in the rock powder act to fully elicit the activity of a nutritional component capable of suppressing mastitis, e.g., vitamin A, vitamin E, copper, zinc and manganese obtained from the feed. In this manner, the onset of mastitis can be suppressed in a nutritional manner, and a therapeutic effect can be achieved on mastitis that has already been developed.
摘要:
The present invention is directed to KIAA1199, which is a novel factor involved in decomposition of hyaluronic acid, and to use thereof. More specifically, the invention is directed to a hyaluronic acid decomposition-promoting agent containing the KIAA1199 gene and a protein encoded by the gene; to a hyaluronic acid decomposition-inhibiting agent characterized by inhibiting the activity or expression thereof (including an siRNA or a monoclonal antibody); and to a method for screening a novel hyaluronic acid decomposition-controlling agent, in which the method contains employing the expression of KIAA1199 as an index.
摘要:
The present invention comprises a virtual volume 50, which is a virtual storage area comprising multiple virtual page groups, a pool 60, which is a storage area comprising multiple pool page groups having different access performance, and a controller 13, which comprises a corresponding relationship between the virtual page and the pool page, and accesses the pool page corresponding to the virtual page based on accesses to the virtual page from other apparatuses, and the controller 13, based on an access load trend with respect to each virtual page in each time slot, executes processing for deciding an ideal pool page allocation destination for each virtual page in each time slot, and reallocating a virtual page to the ideal pool page at a time, which is prior to a start time, so that the ideal pool page can be allocated to each virtual page by the start time of each time slot.
摘要:
A virtualization system, upon judging that a write operation from a higher-level device is an operation to write in the format of the virtual volume, even when the write position of the write operation is in a virtual area different from a virtual area to which an allocated actual area has been allocated, if there is an unused area in the allocated actual area, writes management information to the unused area according to the write operation, and if there is no unused area in the allocated actual area, newly allocates an unallocated actual area, and writes management information to the newly allocated actual area according to the write operation.
摘要:
A skin cosmetic composition comprising the compound represented by the following formula (1): wherein R1 is hydrogen and R2 is hydrogen or glucose residue.