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公开(公告)号：US20150157658A1
公开(公告)日：2015-06-11
申请号：US14622131
申请日：2015-02-13
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Thierry Glauser , Stephen D. Pacetti , Paul M. Consigny
CPC classification number: A61K33/00 , A61K45/06 , A61L29/16 , A61L31/08 , A61L31/10 , A61L31/148 , A61L31/16 , A61L2300/114 , A61L2300/606
Abstract: Medical devices having a catalyst capable of catalyzing the generation of nitric oxide in vivo and methods of treating a vascular condition using the devices are provided.
Abstract translation: 提供了具有能够催化体内产生一氧化氮的催化剂的医疗装置和使用该装置治疗血管状态的方法。
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42.发明申请IMPLANTABLE DEVICES FORMED OF NON-FOULING METHACRYLATE OR ACRYLATE POLYMERS 审中-公开形成非甲基丙烯酸甲酯或丙烯酸酯聚合物的可植入装置公开(公告)号：US20150098977A1
公开(公告)日：2015-04-09
申请号：US14565331
申请日：2014-12-09
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Stephen D. Pacetti
CPC classification number: A61L31/10 , A61L27/34 , A61L27/50 , A61L31/14 , A61L31/16 , A61L33/064 , A61L2300/416 , A61L2300/606 , C08L33/14
Abstract: Implantable devices formed of or coated with a material that includes a polymer having a non-fouling acrylate or methacrylate polymer are provided. The implantable device can be used for treating or preventing a disorder such as atherosclerosis, thrombosis, restenosis, hemorrhage, vascular dissection or perforation, vascular aneurysm, vulnerable plaque, chronic total occlusion, patent foramen ovale, claudication, anastomotic proliferation for vein and artificial grafts, bile duct obstruction, ureter obstruction, tumor obstruction, or combinations thereof.
Abstract translation: 提供了由包含具有非结垢的丙烯酸酯或甲基丙烯酸酯聚合物的聚合物的材料形成或涂覆的可植入装置。 可植入装置可用于治疗或预防动脉粥样硬化，血栓形成，再狭窄，出血，血管解剖或穿孔，血管动脉瘤，易损斑块，慢性完全闭塞，卵圆孔未闭，跛行，静脉和人造移植物的吻合增殖等疾病 ，胆管阻塞，输尿管阻塞，肿瘤阻塞或其组合。
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公开(公告)号：US20150018935A1
公开(公告)日：2015-01-15
申请号：US13937984
申请日：2013-07-09
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Stephen D. Pacetti , Richard Rapoza
IPC: A61F2/82
CPC classification number: A61F2/89 , A61F2/82 , A61F2/91 , A61F2/915 , A61F2002/9155 , A61F2230/0054 , Y10T29/49995
Abstract: An implantable stent includes a plurality of rings. At least a distal end ring has an eased corner feature formed in the polymer substrate at a radially outward, distal-facing corner of the ring while relatively sharp corners of the polymer substrate are maintained in radially inward corners of the ring.
Abstract translation: 可植入支架包括多个环。 至少一个远端环具有形成在聚合物基底中位于环的径向向外的远侧面角处的易折角特征，而聚合物基底的相对尖锐的角保持在环的径向向内的拐角处。
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公开(公告)号：US20150018934A1
公开(公告)日：2015-01-15
申请号：US13937921
申请日：2013-07-09
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Stephen D. Pacetti
IPC: A61F2/89
CPC classification number: A61F2/90 , A61F2/844 , A61F2/89 , A61F2/915 , A61F2230/0069 , A61F2250/0071 , A61F2250/0096 , A61F2250/0098 , A61L31/18
Abstract: An implantable sent comprises a radiopaque marker that provides a structural connection between two parts made of a polymer substrate material. The two parts can be one bending element of one radially expandable ring and another bending element of an adjacent expandable ring. The two parts can be two bending elements of the same radially expandable ring. The radiopaque marker can be in the form of an entire radially expandable ring.
Abstract translation: 可植入的包括不透射线的标记，其提供由聚合物基底材料制成的两个部分之间的结构连接。 两个部件可以是一个可径向扩张的环的一个弯曲元件和相邻可膨胀环的另一个弯曲元件。 两个部件可以是同一径向可扩张环的两个弯曲元件。 不透射线的标记可以是整个可径向扩张的环的形式。
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公开(公告)号：US20140377332A1
公开(公告)日：2014-12-25
申请号：US14086907
申请日：2013-11-21
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Florian N. Ludwig , Stephen D. Pacetti , Syed F.A. Hossainy , Dariush Davalian
CPC classification number: A61K9/5031 , A61K9/0004 , A61K9/0019 , A61K9/5115 , A61K9/5138 , A61K38/446 , A61K41/0052 , A61K47/6923 , A61K47/6925 , A61K47/6929 , A61K47/6931 , A61L31/16 , A61L2300/00 , A61L2400/06 , A61L2400/12 , B01J13/02 , B22F1/025 , B82Y5/00 , Y10S977/773 , Y10S977/906 , Y10T428/2991 , Y10T428/2998
Abstract: Nano-constructs comprising nanoshells and methods of using the nano-constructs for treating or ameliorating a medical condition are provided.
Abstract translation: 提供包含纳米壳的纳米构建体和使用纳米构建体治疗或改善医学状况的方法。
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Patent Agency Ranking
46.发明申请COATINGS FOR IMPLANTABLE DEVICES COMPRISING POLYMERS OF LACTIC ACID AND METHODS FOR FABRICATING THE SAME 审中-公开包含乳酸聚合物的可植入装置的涂料及其制造方法公开(公告)号：US20140377325A1
公开(公告)日：2014-12-25
申请号：US14476623
申请日：2014-09-03
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Syed F.A. Hossainy , Yiwen Tang , Eugene T. Michal , Thierry Glauser , Stephen D. Pacetti , Jessica DesNoyer
CPC classification number: A61L31/10 , A61F2250/0067 , A61L27/28 , A61L27/34 , A61L29/08 , A61L29/085 , A61L31/08 , A61L31/148 , A61L31/16 , A61L2420/00 , A61L2420/02 , A61L2420/06 , C08L67/04
Abstract: Coatings for an implantable medical device and a method of fabricating thereof are disclosed, the coatings comprising polymers of lactic acid.
Abstract translation: 公开了用于可植入医疗装置的涂层及其制造方法，所述涂层包含乳酸聚合物。
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47.发明授权公开(公告)号：US08895056B2
公开(公告)日：2014-11-25
申请号：US13725525
申请日：2012-12-21
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Stephen D. Pacetti , Paul M. Consigny , Ronald W. Heil, Jr. , Florian Niklas Ludwig , Dariush Davalian , Li Zhao , Irina Astafieva , Jinping Wan , Fozan El-Nounou , Katsuyuki Murase , Syed F. A. Hossainy , Rachel Bright , Jeffrey Ellis
CPC classification number: A61M25/1002 , A61F2/82 , A61F2250/0067 , A61K31/27 , A61K31/44 , A61K31/56 , A61K31/66 , A61K38/1709 , A61L29/08 , A61L29/16 , A61L31/08 , A61L31/16 , A61L2300/112 , A61L2300/216 , A61L2300/252 , A61L2300/40 , A61L2300/41 , A61L2300/416 , A61L2300/606 , A61L2300/62 , A61M25/10 , A61M37/0015 , A61M2025/105 , A61M2025/1086 , A61M2037/0023 , A61M2037/0061 , A61M2210/12
Abstract: The present invention relates to the regional delivery of therapeutic agents for the treatment of vascular diseases wherein regional delivery refers to delivery of a therapeutically effective amount of the therapeutic agent to an area of the vessel that includes not only afflicted tissue but non-afflicted tissue at the periphery of the afflicted tissue as well.
Abstract translation: 本发明涉及用于治疗血管疾病的治疗剂的区域递送，其中区域递送是指将治疗有效量的治疗剂递送至血管的区域，该区域不仅包括受到损伤的组织而且包括非折磨组织 受影响组织的外围也是如此。
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公开(公告)号：US20140303708A1
公开(公告)日：2014-10-09
申请号：US14311174
申请日：2014-06-20
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Stephen R. Dugan , Jessica R. DesNoyer , Stephen D. Pacetti , Bozena Zofia Maslanka
CPC classification number: A61L31/10 , A61F2/844 , A61F2/86 , A61F2/915 , A61F2/958 , A61F2002/91533 , A61F2002/91583 , A61L29/14 , A61L31/14 , A61L31/16 , A61L2300/426 , A61L2400/10 , A61L2420/02 , A61L2420/08
Abstract: A medical assembly is disclosed comprises a stent and a catheter having a balloon, wherein the coefficient of friction and/or the adhesion at the stent/balloon interface are reduced.
Abstract translation: 所公开的医疗组件包括支架和具有气囊的导管，其中减小了支架/球囊界面处的摩擦系数和/或粘附力。
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公开(公告)号：US20140277399A1
公开(公告)日：2014-09-18
申请号：US13842445
申请日：2013-03-15
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.
Inventor： Stephen D. Pacetti , John J. Stankus
CPC classification number: A61L27/3695 , A61L27/3604 , A61L31/16 , A61L2400/06 , A61L2430/34
Abstract: A therapeutic formulation is described for a drug delivery balloon comprising a therapeutic formulation which includes a therapeutic agent and an adhesion additive. The adhesion additive promotes adhesion of the therapeutic formulation a vessel wall of a subject. A system and a method of manufacturing a system including an expandable member having a working length with the therapeutic formulation disposed along at least a portion of the working length is also provided.
Abstract translation: 描述了用于包含治疗剂的药物递送球囊的治疗剂型，其包括治疗剂和粘附添加剂。 粘合添加剂促进治疗剂对受试者血管壁的粘附。 还提供了一种制造系统和方法，其包括具有沿着工作长度的至少一部分设置的治疗剂的具有工作长度的可扩张构件的系统和方法。
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50.发明申请SHORT PULSE LASER MACHINING OF POLYMERS ENHANCED WITH LIGHT ABSORBERS FOR FABRICATING MEDICAL DEVICES 有权用于制造医疗器械的轻型吸收器的聚合物的短脉冲激光加工公开(公告)号：US20140263217A1
公开(公告)日：2014-09-18
申请号：US13802189
申请日：2013-03-13
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.
Inventor： Stephen D. Pacetti , Joel Harrington
IPC: B23K26/38
CPC classification number: A61F2/915 , A61F2/91 , A61F2002/91558 , A61F2002/91583 , A61F2240/001 , B23K26/38 , B23K26/402 , B23K2103/42 , B23K2103/50 , B29C35/0805 , B29C2035/0838 , B29K2067/00 , B29K2105/005 , B29K2105/258 , B29K2995/006 , B29L2031/7532
Abstract: A method of laser machining a polymer construct to form a stent that includes a bioresorbable polymer and an absorber that increases absorption of laser energy during laser machining. The laser cuts the tubing at least in part by a multiphoton absorption mechanism and the polymer and absorber have a very low absorbance or are transparent to light at the laser wavelength.
Abstract translation: 激光加工聚合物构造物以形成支架的方法，所述支架包括生物可再吸收聚合物和在激光加工期间增加激光能量吸收的吸收体。 激光至少部分地通过多光子吸收机构切割管道，并且聚合物和吸收体具有非常低的吸光度或对于激光波长的光是透明的。
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