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80 条记录 (耗时 0.052 秒)

    Electrode contact configurations for an implantable stimulator
    43.
    发明授权
    Electrode contact configurations for an implantable stimulator 有权
    可植入刺激器的电极接触配置

    公开(公告)号：US07702385B2

    公开(公告)日：2010-04-20

    申请号：US11280582

    申请日：2005-11-16

    申请人： Michael A. Moffitt ,  Rafael Carbunaru ,  Todd K. Whitehurst ,  Alfred E. Mann

    发明人： Michael A. Moffitt ,  Rafael Carbunaru ,  Todd K. Whitehurst ,  Alfred E. Mann

    IPC分类号： A61N1/05

    CPC分类号： A61N1/375 ,  A61N1/3605 ,  A61N1/37205 ,  A61N1/3756

    摘要： An exemplary implantable stimulator includes at least one electrode contact array and at least one additional electrode contact. Both the electrode contact array and the additional electrode contact are disposed on an external surface of the stimulator. The electrode contact array includes multiple electrode contacts that are configured to have a first polarity. The additional electrode is configured to have a second polarity. One or more of the electrode contacts disposed on the stimulator are configured to deliver monopolar stimulation and/or multipolar stimulation. Exemplary methods of stimulating a stimulation site within a patient include providing at least one electrode contact array and at least one additional electrode contact. Both the electrode contact array and the additional electrode contact are disposed on an external surface of the stimulator. The electrode contact array includes multiple electrode contacts that are configured to have a first polarity. The additional electrode is configured to have a second polarity. The method further includes applying an electrical stimulation current to the stimulation site via one or more of the electrode contacts that are disposed on the stimulator.

    摘要翻译： 示例性可植入刺激器包括至少一个电极接触阵列和至少一个附加电极接触。 电极接触阵列和附加电极接触都设置在刺激器的外表面上。 电极接触阵列包括被配置为具有第一极性的多个电极接触。 附加电极被配置为具有第二极性。 设置在刺激器上的一个或多个电极接触器被配置成传递单极刺激和/或多极刺激。 刺激患者内的刺激部位的示例性方法包括提供至少一个电极接触阵列和至少一个另外的电极接触。 电极接触阵列和附加电极接触都设置在刺激器的外表面上。 电极接触阵列包括被配置为具有第一极性的多个电极接触。 附加电极被配置为具有第二极性。 该方法还包括经由设置在刺激器上的一个或多个电极接触件向刺激部位施加电刺激电流。

    Implanted ceramic case with enhanced ceramic case strength
    45.
    发明授权
    Implanted ceramic case with enhanced ceramic case strength 失效
    嵌入式陶瓷表壳，增强陶瓷表壳强度

    公开(公告)号：US06411854B1

    公开(公告)日：2002-06-25

    申请号：US09353237

    申请日：1999-07-14

    申请人： George Tziviskos ,  Tom J. Law ,  Alfred E. Mann

    发明人： George Tziviskos ,  Tom J. Law ,  Alfred E. Mann

    IPC分类号： A61N1375

    CPC分类号： A61N1/375

    摘要： An implantable medical device is made from an electronic subassembly hermetically sealed in a ceramic case filled with a potting material. Use of the potting material enhances the capacity of the device to withstand mechanical shock without failure. The device includes a hollow ceramic or other case having an open end to which a metal ring is hermetically bonded. The inside surface of the ceramic case is treated (cleansed and activated) to assure the potting material adheres to it. The potting material, while in a non-cured fluid or quasi-fluid state, is inserted inside of the ceramic case. The electronic circuitry is next inserted into the open end of the ceramic case while the potting material is still in a non-cured, soft or fluid state. The electronic circuitry displaces some of the potting material and the potting material fills the voids between the electronic circuitry and the ceramic case. The potting material is then slowly cured, and once cured, supports the walls of the ceramic case and protects the electronic circuitry embedded therein. A header (to which the electronic circuitry is attached) is hermetically bonded to the metal band on the open end of the ceramic case, thereby hermetically sealing the implantable device.

    摘要翻译： 植入式医疗装置由密封在填充有灌封材料的陶瓷壳体中的电子组件制成。 灌封材料的使用增强了设备承受机械冲击而无故障的能力。 该装置包括中空陶瓷或具有开口端的其它壳体，金属环与气密结合。 陶瓷外壳的内表面被处理（清洁和激活），以确保灌封材料粘附在其上。 灌封材料在未固化的流体或准流体状态下插入陶瓷壳体内部。 接下来，电子电路插入到陶瓷外壳的开口端，同时灌封材料仍处于非固化，软或流体状态。 电子电路置换一些灌封材料，并且灌封材料填充电子电路和陶瓷壳体之间的空隙。 灌封材料然后缓慢固化，一旦固化，就支撑陶瓷壳体的壁并保护嵌入其中的电子电路。 将标题（电子电路连接到其上）与陶瓷外壳的开口端上的金属带气密地结合，从而气密地密封可植入装置。

    Fully implantable cochlear implant system
    46.
    发明授权
    Fully implantable cochlear implant system 有权
    完全植入式耳蜗植入系统

    公开(公告)号：US06272382B1

    公开(公告)日：2001-08-07

    申请号：US09407826

    申请日：1999-09-28

    申请人： Michael A. Faltys ,  Janusz A. Kuzma ,  Thomas H. R. Lenarz ,  Alfred E. Mann

    发明人： Michael A. Faltys ,  Janusz A. Kuzma ,  Thomas H. R. Lenarz ,  Alfred E. Mann

    IPC分类号： A61N136

    CPC分类号： A61N1/08 ,  A61N1/36036 ,  A61N1/375 ,  A61N1/3787

    摘要： The present invention provides a fully implantable cochlear implant system (FICIS) that allows various configurations of different modules to be combined so as to meet the needs of a particular patient, including very young patients. At least three main modules are used in the FICIS, including (1) a small implantable cochlear stimulator (ICS) module, with permanently attached cochlear electrode array; (2) an implantable speech processor (ISP) module, with integrated microphone and rechargeable battery; and (3) an external module. In one embodiment, the external module may comprise an external speech processor (ESP) module. In another embodiment, the external module may comprise an external battery charger (EBC) module. The ICS and ISP modules are configured to facilitate long time reliable use of the ICS module, e.g., for the lifetime of the patient, and low-risk, relatively easy replacement of the ISP module.

    摘要翻译： 本发明提供一种完全可植入的人工耳蜗植入系统（FICIS），其允许组合不同模块的各种配置，以便满足特定患者（包括非常年轻的患者）的需要。 FICIS中至少使用三个主要模块，其中包括：（1）一个小型植入式耳蜗刺激器（ICS）模块，具有永久性附加的耳蜗电极阵列; （2）可植入语音处理器（ISP）模块，具有集成麦克风和可充电电池; 和（3）外部模块。 在一个实施例中，外部模块可以包括外部语音处理器（ESP）模块。 在另一个实施例中，外部模块可以包括外部电池充电器（EBC）模块。 ICS和ISP模块被配置为便于长时间可靠地使用ICS模块，例如在患者的寿命期内，以及低风险，相对容易地更换ISP模块。

    Implantable stimulator that prevents DC current flow without the use of discrete output coupling capacitors
    47.
    发明授权
    Implantable stimulator that prevents DC current flow without the use of discrete output coupling capacitors 失效
    可植入式刺激器，可防止直流电流流动而不使用离散输出耦合电容

    公开(公告)号：US06035237A

    公开(公告)日：2000-03-07

    申请号：US447455

    申请日：1995-05-23

    申请人： Joseph H. Schulman ,  Alfred E. Mann ,  John C. Gord ,  Ronald J. Lebel

    发明人： Joseph H. Schulman ,  Alfred E. Mann ,  John C. Gord ,  Ronald J. Lebel

    IPC分类号： A61N1/08 ,  A61N1/32 ,  A61N1/36 ,  A61N1/16

    CPC分类号： A61N1/36142 ,  A61N1/36125

    摘要： An implantable living tissue stimulator avoids the use of conventional coupling capacitors in its output stage, yet still prevents an average dc current flow from flowing through living tissue in electrical contact with the stimulator. The output stage generates and applies a biphasic stimulating current pulse to selected paired output terminals. The terminals, in turn, are electrically connected to respective electrodes which are positioned so as to contact the living tissue to be stimulated. In one embodiment, special circuitry is employed within the output stage to block dc current flow through the living tissue and to balance the electrical charge that is delivered to the living tissue. In another embodiment, the electrodes themselves are made from a material that allows them to function as a capacitor. In yet an additional embodiment, the coupling capacitors are integrated into the leads that connect the output terminals of the output stage with the electrodes.

    摘要翻译： 植入式生物组织刺激器避免了在其输出阶段使用传统的耦合电容器，但仍然阻止平均直流电流流过活组织与刺激器电接触。 输出级产生并将双相刺激电流脉冲施加到选定的配对输出端子。 这些端子又电连接到相应的电极，这些电极定位成接触待刺激的生物体组织。 在一个实施例中，在输出级内采用特殊电路来阻止直流电流流过活组织并平衡输送到生物体组织的电荷。 在另一个实施例中，电极本身由允许它们用作电容器的材料制成。 在又一个实施例中，耦合电容器集成到将输出级的输出端与电极连接的引线中。

    Glucose sensor assembly
    48.
    发明授权
    Glucose sensor assembly 失效
    葡萄糖传感器组件

    公开(公告)号：US5660163A

    公开(公告)日：1997-08-26

    申请号：US444300

    申请日：1995-05-18

    申请人： Joseph H. Schulman ,  Orville Rey Rule, III ,  David I. Whitmoyer ,  Ronald J. Lebel ,  Joseph Y. Lucisano ,  Alfred E. Mann

    发明人： Joseph H. Schulman ,  Orville Rey Rule, III ,  David I. Whitmoyer ,  Ronald J. Lebel ,  Joseph Y. Lucisano ,  Alfred E. Mann

    IPC分类号： A61B5/00

    CPC分类号： A61B5/14865 ,  A61B5/1495 ,  A61B5/6849 ,  A61B2562/08 ,  A61B5/742

    摘要： A glucose monitoring system continuously measures the glucose concentration in a patient's blood, provides an indication of the rate of change of such concentration, and determines whether the measured concentration and rate of change are within certain preset limits. If not, an audible and/or visual alarm signal is generated. The glucose monitoring system includes a glucose sensor adapted to be inserted into the venous system of the patient, where it responds to blood glucose and produces sensor signals related to the glucose concentration. The sensor signals are delivered through a suitable interconnect cable to a glucose monitor. In one embodiment, the interconnect cable includes a contactless connector that electrically isolates the glucose sensor from the monitor, and reduces the number of conductors required to interface with a plurality of sensors. The glucose monitor interprets the sensor signals by applying a previously determined calibration to quantitatively determine the blood glucose value. The blood glucose value thus determined is then processed in order to determine the rate of change, is stored (to create a history or record), and may also be displayed in large, easy-to-read numerals. Rate of change information (trend) may also be numerically or graphically displayed.

    摘要翻译： 葡萄糖监测系统连续测量患者血液中的葡萄糖浓度，提供这种浓度变化率的指示，并确定测量的浓度和变化率是否在某些预设限度内。 如果没有，则产生声音和/或视觉报警信号。 葡萄糖监测系统包括适于插入患者静脉系统中的葡萄糖传感器，其响应于血糖并产生与葡萄糖浓度相关的传感器信号。 传感器信号通过合适的互连电缆传送到葡萄糖监测器。 在一个实施例中，互连电缆包括非接触式连接器，其将葡萄糖传感器与监视器电隔离，并且减少与多个传感器接合所需的导体的数量。 葡萄糖监测器通过应用预先确定的校准来定量地确定血糖值来解释传感器信号。 然后处理如此确定的血糖值以确定变化率，存储（创建历史或记录），并且还可以以大的易于阅读的数字显示。 变化率信息（趋势）也可以数字或图形显示。

    Shield for conductors of an implantable device
    49.
    发明授权
    Shield for conductors of an implantable device 失效
    可植入装置导体的屏蔽

    公开(公告)号：US5477855A

    公开(公告)日：1995-12-26

    申请号：US92748

    申请日：1993-07-16

    申请人： Robert A. Schindler ,  Charles L. Byers ,  Alfred E. Mann ,  James W. Beazell

    发明人： Robert A. Schindler ,  Charles L. Byers ,  Alfred E. Mann ,  James W. Beazell

    IPC分类号： A61N1/08 ,  A61N1/375 ,  A61B5/04

    CPC分类号： A61N1/08 ,  A61N1/375

    摘要： A shield for the conductors extending from an implantable device, provides a cover for the conductors and protects them against being dislodged or moved, by scratching, physical activity, skin pressure or other circumstance. The cover is resilient and flexible and is made of a fabric laminated between layers of an elastomer, such as silicone rubber. The cover is fixedly attached at one end with respect to the implantable device. The cover is suturable to hold the implantable device, cover and conductors in place, thereby providing stabilization. The shield is disposed over the location where the conductors extend from the implanted device and provides strain relief for the conductors and protects them from breakage at that very fragile location. The shield partially or totally encircles the conductors for a short distance.

    摘要翻译： 用于从可植入装置延伸的导体的屏蔽件为导体提供盖子，并通过划伤，身体活动，皮肤压力或其他情况来保护它们免受移动或移动。 该盖具有弹性和柔性，并由层压在诸如硅橡胶之类的弹性体层之间的织物制成。 盖相对于可植入装置的一端固定地固定。 盖子可以固定以将可植入装置，盖子和导体保持就位，从而提供稳定性。 护罩设置在导体从植入装置延伸的位置上，并为导体提供应变消除，并保护它们在该非常脆弱的位置处不破裂。 屏蔽部分或全部围绕导体短距离。