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41.
公开(公告)号:US20060127894A1
公开(公告)日:2006-06-15
申请号:US10486020
申请日:2002-08-08
申请人: Yalda Azimzai , Ines Barroso , Mariah Baughn , Shanya Becha , Mark Borowsky , Brendan Duggan , Vicki Elliott , Brooke Emerling , Ian Forsythe , Kimberly Gietzen , Ann Gorvad , Richard Graul , Jennifer Griffin , Rajagopal Gururajan , April Hafalia , Craig Ison , Amy Kable , Farrah Khan , Sally Lee , Soo Lee , Joana Li , Roopa Reddy , Thomas Richardson , William Sprague , Anita Swarnakar , Y. Tom Tang , Bridget Warren , Yuming Xu , Monique Yao , Henry Yue , Huibin Yue
发明人: Yalda Azimzai , Ines Barroso , Mariah Baughn , Shanya Becha , Mark Borowsky , Brendan Duggan , Vicki Elliott , Brooke Emerling , Ian Forsythe , Kimberly Gietzen , Ann Gorvad , Richard Graul , Jennifer Griffin , Rajagopal Gururajan , April Hafalia , Craig Ison , Amy Kable , Farrah Khan , Sally Lee , Soo Lee , Joana Li , Roopa Reddy , Thomas Richardson , William Sprague , Anita Swarnakar , Y. Tom Tang , Bridget Warren , Yuming Xu , Monique Yao , Henry Yue , Huibin Yue
CPC分类号: C07K14/47 , C07K14/4747 , C07K14/4748 , C12Q1/6883 , C12Q2600/136 , C12Q2600/156 , C12Q2600/158 , G01N33/6872 , G01N2333/47
摘要: Various embodiments of the invention provide human proteins associated with cell growth, differentiation, and death (CGDD) and polynucleotides which identify and encode CGDD. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of CGDD.
摘要翻译: 本发明的各种实施方案提供与细胞生长,分化和死亡(CGDD)相关的人类蛋白质和鉴定和编码CGDD的多核苷酸。 本发明的实施方案还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 其他实施方案提供用于诊断,治疗或预防与CGDD异常表达相关的紊乱的方法。
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公开(公告)号:US06620783B1
公开(公告)日:2003-09-16
申请号:US09571078
申请日:2000-05-15
申请人: Y. Tom Tang , Neil C. Corley , Karl J. Guegler
发明人: Y. Tom Tang , Neil C. Corley , Karl J. Guegler
IPC分类号: A61K3818
CPC分类号: C07K14/475 , A61K38/00
摘要: The invention provides a human SMN-like protein (HSLP) and polynucleotides which identify and encode HSLP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HSLP.
摘要翻译: 本发明提供了人类SMN样蛋白(HSLP)和鉴定和编码HSLP的多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供了治疗或预防与HSLP表达相关的疾病的方法。
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公开(公告)号:US6130064A
公开(公告)日:2000-10-10
申请号:US28327
申请日:1998-02-24
申请人: Y. Tom Tang , Neil C. Corley , Karl J. Guegler
发明人: Y. Tom Tang , Neil C. Corley , Karl J. Guegler
IPC分类号: C12N15/09 , A61K38/00 , A61K39/395 , A61P15/00 , A61P25/00 , A61P35/00 , A61P43/00 , C07K14/47 , C07K14/475 , C07K16/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/12 , C12P21/02 , C12P21/08 , C12Q1/68
CPC分类号: C07K14/475 , A61K38/00
摘要: The invention provides a human SMN-like protein (HSLP) and polynucleotides which identify and encode HSLP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HSLP.
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公开(公告)号:US6077693A
公开(公告)日:2000-06-20
申请号:US79981
申请日:1998-05-14
申请人: Y. Tom Tang , Brian McKelligon , Janice Au-Young , Neil C. Corley , Karl J. Guegler , Chandra Patterson
发明人: Y. Tom Tang , Brian McKelligon , Janice Au-Young , Neil C. Corley , Karl J. Guegler , Chandra Patterson
CPC分类号: C07K14/4747 , C07K14/4702 , A61K38/00
摘要: The invention provides a human promonocyte associated protein (PRMNC) and polynucleotides which identify and encode PRMNC. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of PRMNC.
摘要翻译: 本发明提供了人类促细胞相关蛋白(PRMNC)和识别和编码PRMNC的多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与PRMNC表达相关的疾病的方法。
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公开(公告)号:US6075136A
公开(公告)日:2000-06-13
申请号:US25059
申请日:1998-02-17
申请人: Y. Tom Tang , Neil C. Corley , Karl J. Guegler
发明人: Y. Tom Tang , Neil C. Corley , Karl J. Guegler
IPC分类号: C12N15/09 , A61K38/00 , A61K38/48 , A61K45/00 , A61P13/08 , A61P15/00 , A61P35/00 , C07K16/40 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/64 , C12N15/57 , C12Q1/68 , C07H21/04 , C12N15/11 , C12N15/63
CPC分类号: C12N9/6424 , A61K38/00
摘要: The invention provides a human prostate-associated serine protease (PRASP) and polynucleotides which identify and encode PRASP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of PRASP.
摘要翻译: 本发明提供了人前列腺相关丝氨酸蛋白酶(PRASP)和识别和编码PRASP的多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供了治疗或预防与PRASP表达相关的疾病的方法。
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公开(公告)号:US6013454A
公开(公告)日:2000-01-11
申请号:US162373
申请日:1998-09-28
IPC分类号: G01N33/50 , A61K31/711 , A61K38/00 , A61K39/395 , A61K45/00 , A61K48/00 , A61P1/04 , A61P3/06 , A61P3/10 , A61P5/16 , A61P5/18 , A61P9/08 , A61P13/00 , A61P17/00 , A61P19/00 , A61P19/02 , A61P21/00 , A61P21/04 , A61P25/00 , A61P25/02 , A61P25/08 , A61P25/14 , A61P25/16 , A61P25/18 , A61P25/22 , A61P25/28 , A61P27/02 , A61P29/02 , A61P31/00 , A61P31/04 , A61P31/18 , A61P35/00 , A61P37/02 , A61P37/08 , C07K14/47 , C07K16/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12N15/12 , C12P21/02 , C12Q1/68 , C12R1/91 , G01N33/15 , G01N33/53 , G01N33/566 , C12N1/20 , C12N5/00 , C12N15/00 , C12P21/06
CPC分类号: C07K14/47
摘要: The invention provides a human kinesin-like motor protein (KLIMP) and polynucleotides which identify and encode KLIMP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of KLIMP.
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47.
公开(公告)号:US07371832B1
公开(公告)日:2008-05-13
申请号:US09744196
申请日:1999-07-21
申请人: Y. Tom Tang , Preeti Lal , Jennifer L. Hillman , Neil C. Corley , Chandra Arvizu , Mariah R. Baughn
发明人: Y. Tom Tang , Preeti Lal , Jennifer L. Hillman , Neil C. Corley , Chandra Arvizu , Mariah R. Baughn
CPC分类号: C07K14/4702 , A61K38/00
摘要: The invention provides human molecules associated with cell proliferation (MACP) and polynucleotides which identify and encode MACP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of MACP.
摘要翻译: 本发明提供与细胞增殖相关的人分子(MACP)和识别和编码MACP的多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供了用于诊断,治疗或预防与MACP表达相关的障碍的方法。
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公开(公告)号:US06221843B1
公开(公告)日:2001-04-24
申请号:US09360490
申请日:1999-07-23
IPC分类号: A61K3800
CPC分类号: C07K14/4741
摘要: The invention provides human keratins (KERT) and polynucleotides which identify and encode KERT. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of KERT.
摘要翻译: 本发明提供鉴定和编码KERT的人角蛋白(KERT)和多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与KERT表达相关的障碍的方法。
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公开(公告)号:US6017744A
公开(公告)日:2000-01-25
申请号:US129055
申请日:1998-08-04
申请人: Jennifer L. Hillman , Y. Tom Tang , Neil C. Corley
发明人: Jennifer L. Hillman , Y. Tom Tang , Neil C. Corley
CPC分类号: C12N9/104 , C12Q1/6883 , A61K38/00 , C12Q2600/158
摘要: The invention provides a human N-acetyl transferase (NACTH) and polynucleotides which identify and encode NACTH. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of NACTH.
摘要翻译: 本发明提供了人N-乙酰转移酶(NACTH)和鉴定和编码NACTH的多核苷酸。 本发明还提供表达载体,宿主细胞,激动剂,抗体和拮抗剂。 本发明还提供了治疗与NACTH表达相关的疾病的方法。
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公开(公告)号:US06036954A
公开(公告)日:2000-03-14
申请号:US373029
申请日:1999-08-11
申请人: Y. Tom Tang , Neil C. Corley , Karl J. Guegler , Mariah R. Baughn
发明人: Y. Tom Tang , Neil C. Corley , Karl J. Guegler , Mariah R. Baughn
IPC分类号: G01N33/50 , A61K38/00 , A61K45/00 , A61P21/00 , A61P25/00 , A61P35/00 , A61P37/02 , A61P43/00 , C07K16/40 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/14 , C12N9/16 , C12N15/09 , C12N15/55 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N33/566 , A61K38/46
摘要: The invention provides a human ATP synthase subunit homolog (ASYNT) and polynucleotides which identify and encode ASYNT. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of ASYNT.
摘要翻译: 本发明提供了人ATP合酶亚基同源物(ASYNT)和识别和编码ASYNT的多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供了用于诊断,治疗或预防与ASYNT表达相关的病症的方法。
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