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公开(公告)号：US20060127894A1
公开(公告)日：2006-06-15
申请号：US10486020
申请日：2002-08-08
申请人： Yalda Azimzai , Ines Barroso , Mariah Baughn , Shanya Becha , Mark Borowsky , Brendan Duggan , Vicki Elliott , Brooke Emerling , Ian Forsythe , Kimberly Gietzen , Ann Gorvad , Richard Graul , Jennifer Griffin , Rajagopal Gururajan , April Hafalia , Craig Ison , Amy Kable , Farrah Khan , Sally Lee , Soo Lee , Joana Li , Roopa Reddy , Thomas Richardson , William Sprague , Anita Swarnakar , Y. Tom Tang , Bridget Warren , Yuming Xu , Monique Yao , Henry Yue , Huibin Yue
发明人： Yalda Azimzai , Ines Barroso , Mariah Baughn , Shanya Becha , Mark Borowsky , Brendan Duggan , Vicki Elliott , Brooke Emerling , Ian Forsythe , Kimberly Gietzen , Ann Gorvad , Richard Graul , Jennifer Griffin , Rajagopal Gururajan , April Hafalia , Craig Ison , Amy Kable , Farrah Khan , Sally Lee , Soo Lee , Joana Li , Roopa Reddy , Thomas Richardson , William Sprague , Anita Swarnakar , Y. Tom Tang , Bridget Warren , Yuming Xu , Monique Yao , Henry Yue , Huibin Yue
CPC分类号： C07K14/47 , C07K14/4747 , C07K14/4748 , C12Q1/6883 , C12Q2600/136 , C12Q2600/156 , C12Q2600/158 , G01N33/6872 , G01N2333/47
摘要： Various embodiments of the invention provide human proteins associated with cell growth, differentiation, and death (CGDD) and polynucleotides which identify and encode CGDD. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of CGDD.
摘要翻译： 本发明的各种实施方案提供与细胞生长，分化和死亡（CGDD）相关的人类蛋白质和鉴定和编码CGDD的多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供用于诊断，治疗或预防与CGDD异常表达相关的紊乱的方法。
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公开(公告)号：US20050123912A1
公开(公告)日：2005-06-09
申请号：US10486977
申请日：2002-08-14
申请人： Ines Barroso , Mariah Baughn , Shanya Becha , Julie Blake , Mark Borowsky , Neil Burford , Brendan Duggan , Vicki Elliott , Brooke Emerling , Ian Forsythe , Kimberly Gietzen , Ann Gorvad , Jennifer Griffin , April Hafalia , Cynthia Honchell , Craig Ison , Farrah Khan , Preeti Lal , Ernestine Lee , Sally Lee , Soo Lee , Joana Li , Dyung Lu , Yan Lu , Patricia Lehr-Mason , Danniel Nguyen , Jayalaxmi Ramkumar , William Sprague , Y Tang , Kavitha Thangavelu , Michael Thornton , Uyen Tran , Narinder Chawla , Bridget Warren , Yuming Xu , Monique Yao , Henry Yue , Huibin Yue , Yeganeh Zebarjadian
发明人： Ines Barroso , Mariah Baughn , Shanya Becha , Julie Blake , Mark Borowsky , Neil Burford , Brendan Duggan , Vicki Elliott , Brooke Emerling , Ian Forsythe , Kimberly Gietzen , Ann Gorvad , Jennifer Griffin , April Hafalia , Cynthia Honchell , Craig Ison , Farrah Khan , Preeti Lal , Ernestine Lee , Sally Lee , Soo Lee , Joana Li , Dyung Lu , Yan Lu , Patricia Lehr-Mason , Danniel Nguyen , Jayalaxmi Ramkumar , William Sprague , Y Tang , Kavitha Thangavelu , Michael Thornton , Uyen Tran , Narinder Chawla , Bridget Warren , Yuming Xu , Monique Yao , Henry Yue , Huibin Yue , Yeganeh Zebarjadian
IPC分类号： G01N33/50 , A61K38/00 , A61K45/00 , A61K49/00 , A61P1/00 , A61P1/16 , A61P3/10 , A61P7/00 , A61P9/00 , A61P9/10 , A61P11/00 , A61P11/06 , A61P13/00 , A61P15/00 , A61P17/00 , A61P17/06 , A61P19/00 , A61P19/02 , A61P19/06 , A61P19/10 , A61P21/00 , A61P25/00 , A61P25/14 , A61P25/16 , A61P25/18 , A61P25/28 , A61P27/02 , A61P29/00 , A61P31/04 , A61P31/10 , A61P31/12 , A61P31/18 , A61P33/00 , A61P35/00 , A61P37/02 , A61P37/08 , A61P43/00 , C07K14/47 , C07K16/18 , C12M1/00 , C12M1/34 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/02 , C12N15/09 , C12P21/02 , C12P21/08 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N37/00 , C07H21/04 , C12N9/22
CPC分类号： C07K14/4702 , A61K38/00 , G01N2500/00
摘要： Various embodiments of the invention provide human nucleic acid-associated proteins (NAAP) and polynucleotides which identify and encode NAAP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of NAAP.
摘要翻译： 本发明的各种实施方案提供了识别和编码NAAP的人核酸相关蛋白（NAAP）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供用于诊断，治疗或预防与NAAP异常表达相关的紊乱的方法。
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公开(公告)号：US20050176944A1
公开(公告)日：2005-08-11
申请号：US10487092
申请日：2002-08-16
申请人： Henry Yue , Dyung Lu , Anita Swarnakar , Y. Tang , Jennifer Griffin , Brooke Emerling , Ian Forsythe , Monique Yao , Jayalaxmi Ramkumar , Thomas Richardson , Shanya Becha , Ernestine Lee , Bridget Warren , Patricia Lehr-Mason , Mariah Baughn , Joana Li , Brendan Duggan , Kimberly Gietzen , Preeti Lal , Mark Borowsky , Craig Ison , Kavitha Thangavelu , Yuming Xu , Sally Lee , Vicki Elliott , William Sprague , Yalda Azimzai , April Hafalia , Li Ding , Danniel Nguyen , Cynthia Honchell , Wen Luo , Narinder Chawla , Joseph Marquis , Jennifer Jackson , Uyen Tran
发明人： Henry Yue , Dyung Lu , Anita Swarnakar , Y. Tang , Jennifer Griffin , Brooke Emerling , Ian Forsythe , Monique Yao , Jayalaxmi Ramkumar , Thomas Richardson , Shanya Becha , Ernestine Lee , Bridget Warren , Patricia Lehr-Mason , Mariah Baughn , Joana Li , Brendan Duggan , Kimberly Gietzen , Preeti Lal , Mark Borowsky , Craig Ison , Kavitha Thangavelu , Yuming Xu , Sally Lee , Vicki Elliott , William Sprague , Yalda Azimzai , April Hafalia , Li Ding , Danniel Nguyen , Cynthia Honchell , Wen Luo , Narinder Chawla , Joseph Marquis , Jennifer Jackson , Uyen Tran
IPC分类号： G01N33/50 , A61K38/00 , A61K39/395 , A61K45/00 , A61K49/00 , A61P1/00 , A61P5/00 , A61P5/14 , A61P15/00 , A61P25/00 , A61P29/00 , A61P35/00 , A61P37/06 , C07H21/04 , C07K1/22 , C07K14/47 , C07K16/18 , C07K16/46 , C12M1/00 , C12M1/34 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/00 , C12N9/02 , C12N9/12 , C12N9/14 , C12N9/16 , C12N15/02 , C12N15/09 , C12P21/02 , C12P21/08 , C12Q1/00 , C12Q1/32 , C12Q1/34 , C12Q1/42 , C12Q1/48 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N37/00
CPC分类号： C07K14/4702 , A61K38/00 , C07K14/47 , G01N2500/04
摘要： Various embodiments of the invention provide human intracellular signaling molecules (INTSIG) and polynucleotides which identify and encode INTSIG. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of INTSIG.
摘要翻译： 本发明的各种实施方案提供了识别和编码INTSIG的人细胞内信号分子（INTSIG）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供用于诊断，治疗或预防与INTSIG的异常表达相关的紊乱的方法。
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公开(公告)号：US20050107588A1
公开(公告)日：2005-05-19
申请号：US10495148
申请日：2002-11-13
申请人： Brendan Duggan , Junming Yang , Kimberly Gietzen , Soo Lee , Y. Tang , Yalda Azimzai , Narinder Chawla , Bridget Warren , Ines Barroso , Shanya Becha , Henry Yue , Patricia Lehr-Mason , Kavitha Thangavelu , Sally Lee , Brooke Emerling , Amy Kable , Reena Khare , Mariah Baughn , Ameena Gandhi , Uyen Tran , Thomas Richardson , Joseph Marquis , Preeti Lal , Ian Forsythe , Ernestine Lee , Anita Swarnakar , Deborah Kallick , Jennifer Griffin , Vicki Elliott , Ann Gorvad , April Hafalia , Craig Ison , Pei Jin , Xin Jiang , Alan Jackson , Umesh Bhatia , John Burrill , Julie Blake , Anne Ho , Wenjin Zheng , Jing Gao
发明人： Brendan Duggan , Junming Yang , Kimberly Gietzen , Soo Lee , Y. Tang , Yalda Azimzai , Narinder Chawla , Bridget Warren , Ines Barroso , Shanya Becha , Henry Yue , Patricia Lehr-Mason , Kavitha Thangavelu , Sally Lee , Brooke Emerling , Amy Kable , Reena Khare , Mariah Baughn , Ameena Gandhi , Uyen Tran , Thomas Richardson , Joseph Marquis , Preeti Lal , Ian Forsythe , Ernestine Lee , Anita Swarnakar , Deborah Kallick , Jennifer Griffin , Vicki Elliott , Ann Gorvad , April Hafalia , Craig Ison , Pei Jin , Xin Jiang , Alan Jackson , Umesh Bhatia , John Burrill , Julie Blake , Anne Ho , Wenjin Zheng , Jing Gao
IPC分类号： C07K14/47 , C07K14/705 , C07H21/04
CPC分类号： C07K14/705 , C07K14/47
摘要： Various embodiments of the invention provide human receptors and membrane-associated proteins (REMAP) and polynucleotides which identify and encode REMAP. Embodiments of the invention also provide expression vectors, host cells, anti-bodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of REMAP.
摘要翻译： 本发明的各种实施方案提供了识别和编码REMAP的人受体和膜相关蛋白（REMAP）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供用于诊断，治疗或预防与REMAP异常表达相关的紊乱的方法。
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公开(公告)号：US20050048490A1
公开(公告)日：2005-03-03
申请号：US10491213
申请日：2002-09-26
申请人： Yalda Azimzai , Mariah Baughn , Shanya Becha , Mark Borowsky , Narinder Chawla , Vicki Elliott , Brooke Emerling , Ameena Gandhi , Kimberly Gietzen , Ann Gorvad , Jennifer Griffin , April Hafalia , Craig Ison , Amu Kable , Daniel Kalafus , Patircia Lehr-Mason , Dyung Aina Lu , Joseph Marquis , Danniel Nguyen , Jayalaxmi Ramkumar , Thomas Richardson , Stephanie Kareht , Anita Swarnakar , Y Tom Tang , Uyen Tran , Bridget Warren , Yuming Xu , Monique Yao , Huibin Yue , Henry Yue
发明人： Yalda Azimzai , Mariah Baughn , Shanya Becha , Mark Borowsky , Narinder Chawla , Vicki Elliott , Brooke Emerling , Ameena Gandhi , Kimberly Gietzen , Ann Gorvad , Jennifer Griffin , April Hafalia , Craig Ison , Amu Kable , Daniel Kalafus , Patircia Lehr-Mason , Dyung Aina Lu , Joseph Marquis , Danniel Nguyen , Jayalaxmi Ramkumar , Thomas Richardson , Stephanie Kareht , Anita Swarnakar , Y Tom Tang , Uyen Tran , Bridget Warren , Yuming Xu , Monique Yao , Huibin Yue , Henry Yue
CPC分类号： G01N33/74 , C07H21/04 , C07K14/4747 , G01N2500/00
摘要： Various embodiments of the invention provide human proteins associated with cell growth, differentiation, and death (CGDD) and polynucleotides whichidentify and encode CGDD. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of CGDD.
摘要翻译： 本发明的各种实施方案提供与细胞生长，分化和死亡（CGDD）相关的人类蛋白质和识别和编码CGDD的多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供用于诊断，治疗或预防与CGDD异常表达相关的紊乱的方法。
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公开(公告)号：US20050191627A1
公开(公告)日：2005-09-01
申请号：US10491183
申请日：2002-09-26
申请人： Junming Yang , Aina Dyung Lu , Henry Yue , Vicki Elliott , Bridget Warren , Brendan Duggan , Ian Forsythe , Ernestine Lee , April Hafalia , Jayalaxmi Ramkumar , Narinder Chawla , Mariah Baughn , Shanya Becha , Ann Gorvad , Uyen Tran , Joana Li , Monique Yao , Craig Ison , Jennifer Griffin , Soo Lee , Hsin-Ru Chang , Brooke Emerling , Tom Tang , Preeti Lal , Amy Kable , Joseph Marquis , Xin Jiang , Alan Jackson , Yeganeh Zebarjadian , Anita Swarnakar , Amy Wilson , Pei Jin , Thomas Richardson , Umesh Bhatia , John Burrill , Sally Lee , Julie Blake , Anne Ho , Wenjin Zheng , Jin Gao
发明人： Junming Yang , Aina Dyung Lu , Henry Yue , Vicki Elliott , Bridget Warren , Brendan Duggan , Ian Forsythe , Ernestine Lee , April Hafalia , Jayalaxmi Ramkumar , Narinder Chawla , Mariah Baughn , Shanya Becha , Ann Gorvad , Uyen Tran , Joana Li , Monique Yao , Craig Ison , Jennifer Griffin , Soo Lee , Hsin-Ru Chang , Brooke Emerling , Tom Tang , Preeti Lal , Amy Kable , Joseph Marquis , Xin Jiang , Alan Jackson , Yeganeh Zebarjadian , Anita Swarnakar , Amy Wilson , Pei Jin , Thomas Richardson , Umesh Bhatia , John Burrill , Sally Lee , Julie Blake , Anne Ho , Wenjin Zheng , Jin Gao
CPC分类号： C12N9/00
摘要： Various embodiments of the invention provide human enzymes (ENZM) and polynucleotides which identify and encode ENZM. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of ENZM.
摘要翻译： 本发明的各种实施方案提供了识别和编码ENZM的人类酶（ENZM）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供用于诊断，治疗或预防与ENZM异常表达相关的紊乱的方法。
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公开(公告)号：US20050033018A1
公开(公告)日：2005-02-10
申请号：US10477714
申请日：2002-05-16
申请人： Preeti Lal , Bridget Warren , Yuming Xu , Brendan Duggan , Cynthia Honchell , Deborah Kallick , Mariah Baughn , Y. Tang , Henry Yue , Olga Bandman , Karen Jones , Shanya Becha , Uyen Tran , Janice Au-Young , Jennifer Griffin , Yeganeh Zebarjadian , Ernestie Lee , Vicki Elliott , Kavitha Thangavelu , Jayalaxmi Ramkumar , Yan Lu , April Hafalia , Narinder Chawla , Craig Ison , Michael Thornton , Anita Swarnakar , Junming Yang , Thomas Richardson , Brooke Emerling , Monique Yao , Benjamin Cocks , Bharati Sanjanwala , Patricia Mason , Ameena Gandhi , Joana Li , Rajagopal Gururajan , Kimberly Gietzen , Ian Forsythe
发明人： Preeti Lal , Bridget Warren , Yuming Xu , Brendan Duggan , Cynthia Honchell , Deborah Kallick , Mariah Baughn , Y. Tang , Henry Yue , Olga Bandman , Karen Jones , Shanya Becha , Uyen Tran , Janice Au-Young , Jennifer Griffin , Yeganeh Zebarjadian , Ernestie Lee , Vicki Elliott , Kavitha Thangavelu , Jayalaxmi Ramkumar , Yan Lu , April Hafalia , Narinder Chawla , Craig Ison , Michael Thornton , Anita Swarnakar , Junming Yang , Thomas Richardson , Brooke Emerling , Monique Yao , Benjamin Cocks , Bharati Sanjanwala , Patricia Mason , Ameena Gandhi , Joana Li , Rajagopal Gururajan , Kimberly Gietzen , Ian Forsythe
IPC分类号： G01N33/50 , A61K45/00 , A61K49/00 , A61P1/00 , A61P3/00 , A61P25/00 , A61P29/00 , A61P31/12 , A61P35/00 , A61P37/06 , C07K14/47 , C07K14/705 , C07K16/28 , C07K16/46 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/02 , C12N15/09 , C12P21/02 , C12P21/08 , C12Q1/02 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N33/566 , C07H21/04
CPC分类号： C07K14/705 , C07K14/47
摘要： The invention provides human receptors and membrane-associated proteins (REMAP) and polynucleotides which identify and encode REMAP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of REMAP.
摘要翻译： 本发明提供鉴定和编码REMAP的人受体和膜相关蛋白（REMAP）和多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供用于诊断，治疗或预防与REMAP的异常表达相关的紊乱的方法。
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公开(公告)号：US20050064543A1
公开(公告)日：2005-03-24
申请号：US10487078
申请日：2002-08-15
申请人： Y. Tang , Bridget Warren , Kimberly Gietzen , Preeti Lal , Henry Yue , Cynthia Honchell , Patricia Lehr-Mason , Neil Burford , Yuming Xu , Mariah Baughn , Brendan Duggan , Uyen Tran , Ernestine Lee , Ian Forsythe , Thomas Richardson , Sally Lee , Kavitha Thangavelu , Huibin Yue , Brooke Emerling , Narinder Chawla , Yalda Azimzai , Bharati Sanjanwala , April Hafalia , Mark Borowsky , Danniel Nguyen , Craig Ison , Anna Astromoff , Li Ding , Soo Yeun Lee , Shanya Becha , Jayalaxmi Ramkumar , Ameena Gandhi , Pei Jin , Glenn Fu , Anita Swarnakar
发明人： Y. Tang , Bridget Warren , Kimberly Gietzen , Preeti Lal , Henry Yue , Cynthia Honchell , Patricia Lehr-Mason , Neil Burford , Yuming Xu , Mariah Baughn , Brendan Duggan , Uyen Tran , Ernestine Lee , Ian Forsythe , Thomas Richardson , Sally Lee , Kavitha Thangavelu , Huibin Yue , Brooke Emerling , Narinder Chawla , Yalda Azimzai , Bharati Sanjanwala , April Hafalia , Mark Borowsky , Danniel Nguyen , Craig Ison , Anna Astromoff , Li Ding , Soo Yeun Lee , Shanya Becha , Jayalaxmi Ramkumar , Ameena Gandhi , Pei Jin , Glenn Fu , Anita Swarnakar
IPC分类号： G01N33/50 , A61K38/00 , A61K39/395 , A61K45/00 , A61P9/00 , A61P25/00 , A61P29/00 , A61P37/06 , A61P43/00 , C07K1/22 , C07K14/47 , C07K14/705 , C07K16/18 , C07K16/46 , C07K19/00 , C12M1/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/12 , C12N9/16 , C12N9/64 , C12N15/02 , C12N15/09 , C12N15/11 , C12P21/02 , C12P21/08 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N37/00 , C07H21/04 , C12N9/00
CPC分类号： C07K14/47 , A01K2217/05 , A61K38/00 , C07K14/705 , C12N9/1205 , C12N9/16 , C12N9/6421
摘要： Various embodiments of the invention provide human secreted proteins(SECP) and polynucleotides which identify and encode SECP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of SECP.
摘要翻译： 本发明的各种实施方案提供鉴定和编码SECP的人分泌蛋白（SECP）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其它实施方案提供用于诊断，治疗或预防与SECP异常表达相关的疾病的方法。
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公开(公告)号：US20050118582A1
公开(公告)日：2005-06-02
申请号：US10483505
申请日：2002-07-10
申请人： Anita Swarnakar , Thomas Richardson , Bridget Warren , Jennifer Griffin , Y Tang , Henry Yue , Mariah Baughn , Brooke Emerling , Preeti Lal , Dyung Lu , Ian Forsythe , Jayalaxmi Ramkumar , Joana Li , Shanya Becha , Brendan Duggan , Madhusudan Sanjanwala , Ernestine Lee , Neil Burford , Vicki Elliott , Craig Ison , Li Ding , Mark Borowsky , Monique Yao , Ines Barroso , Bao Tran , Narinder Chawla , April Hafalia , Danniel Nguyen , Yan Lu , Chandra Arvizu
发明人： Anita Swarnakar , Thomas Richardson , Bridget Warren , Jennifer Griffin , Y Tang , Henry Yue , Mariah Baughn , Brooke Emerling , Preeti Lal , Dyung Lu , Ian Forsythe , Jayalaxmi Ramkumar , Joana Li , Shanya Becha , Brendan Duggan , Madhusudan Sanjanwala , Ernestine Lee , Neil Burford , Vicki Elliott , Craig Ison , Li Ding , Mark Borowsky , Monique Yao , Ines Barroso , Bao Tran , Narinder Chawla , April Hafalia , Danniel Nguyen , Yan Lu , Chandra Arvizu
CPC分类号： C07K14/4702
摘要： Various embodiments of the invention provide human nucleic acid-associated proteins (NAAP) and polynucleotides which identify and encode NAAP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of NAAP.
摘要翻译： 本发明的各种实施方案提供了识别和编码NAAP的人核酸相关蛋白（NAAP）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供用于诊断，治疗或预防与NAAP异常表达相关的紊乱的方法。
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公开(公告)号：US20060115813A1
公开(公告)日：2006-06-01
申请号：US10480962
申请日：2002-06-06
申请人： Junming Yang , Brooke Emerling , Y Tang , Mariah Baugh , Ernestine Lee , Jayalaxmi Ramkumar , Henry Yue , Jennifer Griffin , Narinder Chawla , Bao Tran , Danniel Nguyen , Farrah Khan , Ameena Gandhi , April Hafalia , Anita Swarnakar , Rajagopal Gururajan , Jennifer Policky , Monique Yao , Bridget Warren , Kimberly Gietzen , Vicki Elliott , Soo Lee , Bharati Sanjanwala , Cynthia Honchell , Ian Forsythe , Ann Gorvad , Thomas Richardson , Sally Lee , Ines Barroso
发明人： Junming Yang , Brooke Emerling , Y Tang , Mariah Baugh , Ernestine Lee , Jayalaxmi Ramkumar , Henry Yue , Jennifer Griffin , Narinder Chawla , Bao Tran , Danniel Nguyen , Farrah Khan , Ameena Gandhi , April Hafalia , Anita Swarnakar , Rajagopal Gururajan , Jennifer Policky , Monique Yao , Bridget Warren , Kimberly Gietzen , Vicki Elliott , Soo Lee , Bharati Sanjanwala , Cynthia Honchell , Ian Forsythe , Ann Gorvad , Thomas Richardson , Sally Lee , Ines Barroso
摘要： Various embodiments of the invention provide human intracellular signaling molecules (INTSIG) and polynucleotides which identify and encode INTSIG. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of INTSIG.
摘要翻译： 本发明的各种实施方案提供了识别和编码INTSIG的人细胞内信号分子（INTSIG）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供用于诊断，治疗或预防与INTSIG的异常表达相关的紊乱的方法。
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