Measurement of coronary sinus parameters to optimize left ventricular performance
    45.
    发明申请
    Measurement of coronary sinus parameters to optimize left ventricular performance 有权
    测量冠状窦参数以优化左心室的表现

    公开(公告)号:US20060247702A1

    公开(公告)日:2006-11-02

    申请号:US11116876

    申请日:2005-04-28

    IPC分类号: A61N1/365

    摘要: In some embodiments, an implantable medical device (IMD) system may include one or more of the following elements: (a) an oxygen sensor for measuring oxygen extraction from blood flowing through a coronary sinus of a patient's heart, (b) an oxygen signal generated by the oxygen sensor, (c) an IMD coupled to the oxygen sensor, wherein the IMD is configured to output pacing pulses as a function of the oxygen signal, and (d) an atrial and a ventricular pacing lead coupled to the IMD to deliver the pacing pulses to the patient's heart, wherein the IMD generates the pacing pulses as a function of the oxygen signal, wherein the pacing pulses are adjusted by the IMD as a function of the oxygen signal, wherein the IMD is configured to adjust the pacing pulses to increase oxygen in the blood flow through the coronary sinus.

    摘要翻译: 在一些实施例中,可植入医疗装置(IMD)系统可以包括以下元件中的一个或多个:(a)氧传感器,用于测量从流过患者心脏的冠状窦的血液中提取氧气,(b)氧信号 由氧传感器产生的,(c)耦合到所述氧传感器的IMD,其中所述IMD被配置为输出作为所述氧信号的函数的起搏脉冲,以及(d)心房和心室起搏线,其耦合到所述IMD至 将起搏脉冲递送到患者的心脏,其中IMD根据氧信号产生起搏脉冲,其中起搏脉冲作为氧信号的函数由IMD调节,其中IMD被配置为调整起搏 脉冲以增加通过冠状窦的血液中的氧气。

    Monolithic electrodes and pH transducers
    47.
    发明授权
    Monolithic electrodes and pH transducers 有权
    单片电极和pH传感器

    公开(公告)号:US08728289B2

    公开(公告)日:2014-05-20

    申请号:US11304065

    申请日:2005-12-15

    IPC分类号: G01N27/333

    CPC分类号: G01N27/4035

    摘要: The disclosure provides monolithic electrodes including a substrate defining a walled cavity having a floor, an electrically conductive cathode layer overlaying the cavity floor, an electrically conductive contact pad overlaying the substrate, an electrically conductive via in electrical communication with the cathode layer and the contact pad, and a porous membrane layer overlaying the cavity and defining a chamber formed by the porous membrane layer, the walled cavity, and the cavity floor. The disclosure also provides pH transducers including monolithic indicator and reference electrodes, and methods of making and using monolithic pH electrodes and transducers.

    摘要翻译: 本公开提供了单片电极,其包括限定具有底板的壁腔的衬底,覆盖空腔底板的导电阴极层,覆盖衬底的导电接触垫,与阴极层和接触垫电连通的导电通孔 以及覆盖所述空腔并且限定由所述多孔膜层,所述壁腔和所述空腔底板形成的室的多孔膜层。 本公开还提供了包括单片指示剂和参比电极的pH换能器,以及制造和使用单片pH电极和换能器的方法。

    Wafer level hermetically sealed MEMS device
    49.
    发明授权
    Wafer level hermetically sealed MEMS device 有权
    晶圆级气密密封的MEMS器件

    公开(公告)号:US07816745B2

    公开(公告)日:2010-10-19

    申请号:US11066820

    申请日:2005-02-25

    IPC分类号: H01L23/10

    摘要: A hermetically sealed microelectromechanical system (MEMS) package includes a MEMS switch having a movable portion and a stationary portion with an electrical contact thereon. A glass lid is anodically bonded to the MEMS switch to form a sealed cavity over the movable portion of the MEMS switch. The glass lid includes a contact aperture to allow access to the electrical contact on the stationary portion of the MEMS switch. A family of body-implantable hermetically-sealed MEMS packages are provided according to certain aspects and embodiments of the present invention.

    摘要翻译: 密封的微机电系统(MEMS)封装包括具有可移动部分的MEMS开关和在其上具有电接触的固定部分。 玻璃盖阳极结合到MEMS开关,以在MEMS开关的可移动部分上形成密封空腔。 玻璃盖包括接触孔,以允许接近MEMS开关的固定部分上的电接触。 根据本发明的某些方面和实施例提供了一系列可植入人体的气密密封的MEMS封装。

    Monolithic electrodes and pH transducers
    50.
    发明申请
    Monolithic electrodes and pH transducers 有权
    单片电极和pH传感器

    公开(公告)号:US20070138027A1

    公开(公告)日:2007-06-21

    申请号:US11304065

    申请日:2005-12-15

    IPC分类号: G01F1/64 G01N27/26

    CPC分类号: G01N27/4035

    摘要: The disclosure provides monolithic electrodes including a substrate defining a walled cavity having a floor, an electrically conductive cathode layer overlaying the cavity floor, an electrically conductive contact pad overlaying the substrate, an electrically conductive via in electrical communication with the cathode layer and the contact pad, and a porous membrane layer overlaying the cavity and defining a chamber formed by the porous membrane layer, the walled cavity, and the cavity floor. The disclosure also provides pH transducers including monolithic indicator and reference electrodes, and methods of making and using monolithic pH electrodes and transducers.

    摘要翻译: 本公开提供了单片电极,其包括限定具有底板的壁腔的衬底,覆盖空腔底板的导电阴极层,覆盖衬底的导电接触垫,与阴极层和接触垫电连通的导电通孔 以及覆盖所述空腔并且限定由所述多孔膜层,所述壁腔和所述空腔底板形成的室的多孔膜层。 本公开还提供了包括单片指示剂和参比电极的pH换能器,以及制造和使用单片pH电极和换能器的方法。