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公开(公告)号:US20100099617A1
公开(公告)日:2010-04-22
申请号:US12585371
申请日:2009-09-14
申请人: Henry Yue , Monique G. Yao , Ameena R. Gandhi , Mariah R. Baughn , Anita Swarnakar , Narinder K. Chawla , Madhusudan M. Sanjanwala , Michael B. Thornton , Vicki S. Elliott , Yan Lu , Kimberly J. Gietzen , Neil Burford , Li Ding , April J. A. Hafalia , Y. Tom Tang , Olga Bandman , Bridget A. Warren , Cynthia D. Honchell , Dyung Aina M. Lu , Kavitha Thangavelu , Sally Lee , Yuming Xu , Junming Yang , Preeti G. Lal , Bao Tran , Craig H. Ison , Brendan M. Duggan , Stephanie K. Sapperstein
发明人: Henry Yue , Monique G. Yao , Ameena R. Gandhi , Mariah R. Baughn , Anita Swarnakar , Narinder K. Chawla , Madhusudan M. Sanjanwala , Michael B. Thornton , Vicki S. Elliott , Yan Lu , Kimberly J. Gietzen , Neil Burford , Li Ding , April J. A. Hafalia , Y. Tom Tang , Olga Bandman , Bridget A. Warren , Cynthia D. Honchell , Dyung Aina M. Lu , Kavitha Thangavelu , Sally Lee , Yuming Xu , Junming Yang , Preeti G. Lal , Bao Tran , Craig H. Ison , Brendan M. Duggan , Stephanie K. Sapperstein
IPC分类号: A61K38/16 , C07K14/00 , A61K38/22 , C07K14/575 , A61P35/00 , A61P29/00 , A61P37/00 , A61P25/00 , A61P9/00 , C12P21/02
CPC分类号: C12N15/1055 , A61K39/3955 , A61K47/64 , A61K47/643 , A61K2039/505 , C07K14/47 , C07K14/4711 , C07K14/4713 , C07K16/18 , C07K2317/24 , C07K2317/54 , C07K2317/55 , C07K2317/622 , C07K2317/75 , C07K2317/76 , G01N33/5023
摘要: The invention provides human secreted proteins (SECP) and polynucleotides which identify and encode SECP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of SECP.
摘要翻译: 本发明提供鉴定和编码SECP的人分泌蛋白(SECP)和多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与SECP异常表达相关的疾病的方法。
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公开(公告)号:US07411052B2
公开(公告)日:2008-08-12
申请号:US10488423
申请日:2002-08-30
申请人: Y. Tom Tang
发明人: Y. Tom Tang
CPC分类号: C07K14/475
摘要: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted stem cell growth factor-like polypeptides. Other aspects of the invention include vectors containing processes for producing novel human secreted stem cell growth factor-like polypeptides, and antibodies specific for such polypeptides.
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公开(公告)号:US20080182977A1
公开(公告)日:2008-07-31
申请号:US12078134
申请日:2008-03-27
申请人: Y. Tom Tang , Preeti Lal , Jennifer L. Hillman , Neil C. Corley , Chandra Arvizu , Mariah R. Baughn
发明人: Y. Tom Tang , Preeti Lal , Jennifer L. Hillman , Neil C. Corley , Chandra Arvizu , Mariah R. Baughn
IPC分类号: C07K16/18 , C07K14/435 , C12P21/00
CPC分类号: C07K14/4702 , A61K38/00
摘要: The invention provides human molecules associated with cell proliferation (MACP) and polynucleotides which identify and encode MACP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of MACP.
摘要翻译: 本发明提供与细胞增殖相关的人分子(MACP)和识别和编码MACP的多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供了用于诊断,治疗或预防与MACP表达相关的障碍的方法。
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公开(公告)号:US20070009886A1
公开(公告)日:2007-01-11
申请号:US10534578
申请日:2003-11-10
申请人: Narinder Chawla , Y. Tom Tang , Jennifer Griffin , Yonghong Yang , Jayalaxmi Ramkumar , Reena Khare , Thomas Richardson , Shanya Becha , Uyen Tran , Amy Kable , Anita Swarnakar , Bridget Warren , Vicki Elliott , Joseph Marquis , April Hafalia
发明人: Narinder Chawla , Y. Tom Tang , Jennifer Griffin , Yonghong Yang , Jayalaxmi Ramkumar , Reena Khare , Thomas Richardson , Shanya Becha , Uyen Tran , Amy Kable , Anita Swarnakar , Bridget Warren , Vicki Elliott , Joseph Marquis , April Hafalia
CPC分类号: C07K14/47 , C07K14/4726
摘要: Various embodiments of the invention provide human carbohydrate-associated proteins (CHOP) and polynucleotides which identify and encode CHOP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of CHOP.
摘要翻译: 本发明的各种实施方案提供了识别和编码CHOP的人碳水化合物相关蛋白(CHOP)和多核苷酸。 本发明的实施方案还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 其他实施方案提供用于诊断,治疗或预防与CHOP异常表达相关的障碍的方法。
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公开(公告)号:US06962799B2
公开(公告)日:2005-11-08
申请号:US10362247
申请日:2001-08-20
申请人: Henry Yue , Danniel B. Nguyen , Catherine M. Tribouley , Olga Bandman , Y. Tom Tang , Preeti G. Lal , Narinder K. Chawla , Jennifer L. Policky
发明人: Henry Yue , Danniel B. Nguyen , Catherine M. Tribouley , Olga Bandman , Y. Tom Tang , Preeti G. Lal , Narinder K. Chawla , Jennifer L. Policky
IPC分类号: G01N33/50 , A61K38/00 , A61K45/00 , A61P25/00 , A61P35/00 , A61P37/00 , A61P43/00 , C07K14/47 , C07K16/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/02 , C12N15/09 , C12P21/02 , C12P21/08 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N33/566 , C07H21/04
CPC分类号: C07K14/47 , A01K2217/05
摘要: The invention provides human microtubule-associated proteins and tubulins (MICAPTUB) and polynucleotides which identify and encode MICAPTUB. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of MICAPTUB.
摘要翻译: 本发明提供了人微管相关蛋白和微管蛋白(MICAPTUB)和识别和编码MICAPTUB的多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与MICAPTUB的异常表达相关的疾病的方法。
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公开(公告)号:US06511833B1
公开(公告)日:2003-01-28
申请号:US09481277
申请日:2000-01-11
申请人: Olga Bandman , Jennifer L. Hillman , Karl J. Guegler , Neil C. Corley , Y. Tom Tang , Purvi Shah
发明人: Olga Bandman , Jennifer L. Hillman , Karl J. Guegler , Neil C. Corley , Y. Tom Tang , Purvi Shah
IPC分类号: C12N902
CPC分类号: C12N9/001
摘要: The invention provides human fatty acid beta-oxidation enzymes (HUFA) and polynucleotides which identify and encode HUFA. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HUFA.
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公开(公告)号:US06132714A
公开(公告)日:2000-10-17
申请号:US382027
申请日:1999-08-24
申请人: Y. Tom Tang , Henry Yue , Karl J. Guegler , Purvi Shah
发明人: Y. Tom Tang , Henry Yue , Karl J. Guegler , Purvi Shah
CPC分类号: C12N9/1007 , C07K2319/00 , C12N2799/026
摘要: The invention provides a human growth-associated methyltransferase (GAMT) and polynucleotides which identify and encode GAMT. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of GAMT.
摘要翻译: 本发明提供了与人生长相关的甲基转移酶(GAMT)和识别和编码GAMT的多核苷酸。 本发明还提供了表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供了治疗或预防与GAMT表达相关的疾病的方法。
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公开(公告)号:US6100036A
公开(公告)日:2000-08-08
申请号:US212149
申请日:1998-12-15
申请人: Preeti Lal , Y. Tom Tang , Neil C. Corley
发明人: Preeti Lal , Y. Tom Tang , Neil C. Corley
CPC分类号: C12N9/0036
摘要: The invention provides a human NADH dehydrogenase B17 subunit (NDB17) and polynucleotides which identify and encode NDB17. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of NDB17.
摘要翻译: 本发明提供了人NADH脱氢酶B17亚基(NDB17)和识别和编码NDB17的多核苷酸。 本发明还提供表达载体,宿主细胞,激动剂,抗体和拮抗剂。 本发明还提供了治疗与NDB17表达相关的疾病的方法。
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公开(公告)号:US08153398B2
公开(公告)日:2012-04-10
申请号:US12457389
申请日:2009-06-09
申请人: Preeti G. Lal , Y. Tom Tang , Gina A. Gorgone Simone , Neil C. Corley , Karl J. Guegler , Mariah R. Baughn , Ingrid E. Akerblom , Janice K. Au-Young , Henry Yue , Chandra S. Arvizu , Roopa M. Reddy , Jennifer L. Hillman , Olga Bandman
发明人: Preeti G. Lal , Y. Tom Tang , Gina A. Gorgone Simone , Neil C. Corley , Karl J. Guegler , Mariah R. Baughn , Ingrid E. Akerblom , Janice K. Au-Young , Henry Yue , Chandra S. Arvizu , Roopa M. Reddy , Jennifer L. Hillman , Olga Bandman
CPC分类号: G01N33/57419 , A61K38/00 , A61K38/1709 , A61K39/3955 , A61K45/06 , C07K14/47 , C07K16/18 , C07K16/40 , C07K2317/76 , G01N2333/916
摘要: The invention provides human signal peptide-containing proteins (HSPP) and polynucleotides which identify and encode HSPP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of HSPP.
摘要翻译: 本发明提供了人信号肽肽蛋白(HSPP)和识别和编码HSPP的多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与HSPP表达相关的障碍的方法。
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公开(公告)号:US20110053217A1
公开(公告)日:2011-03-03
申请号:US12457389
申请日:2009-06-09
申请人: Preeti Lal , Y. Tom Tang , Gina A. Gorgone , Neil C. Corley , Karl J. Guegler , Mariah R. Baughn , Ingrid E. Akerblom , Janice Au-Young , Henry Yue , Chandra Patterson , Roopa Reddy , Jennifer L. Hillman , Olga Bandman
发明人: Preeti Lal , Y. Tom Tang , Gina A. Gorgone , Neil C. Corley , Karl J. Guegler , Mariah R. Baughn , Ingrid E. Akerblom , Janice Au-Young , Henry Yue , Chandra Patterson , Roopa Reddy , Jennifer L. Hillman , Olga Bandman
IPC分类号: C12P21/00 , C07H21/04 , C12N1/21 , C07H21/02 , C07K14/435
CPC分类号: G01N33/57419 , A61K38/00 , A61K38/1709 , A61K39/3955 , A61K45/06 , C07K14/47 , C07K16/18 , C07K16/40 , C07K2317/76 , G01N2333/916
摘要: The invention provides human signal peptide-containing proteins (HSPP) and polynucleotides which identify and encode HSPP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of HSPP.
摘要翻译: 本发明提供了人信号肽肽蛋白(HSPP)和识别和编码HSPP的多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与HSPP表达相关的障碍的方法。
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