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公开(公告)号:US06962799B2
公开(公告)日:2005-11-08
申请号:US10362247
申请日:2001-08-20
申请人: Henry Yue , Danniel B. Nguyen , Catherine M. Tribouley , Olga Bandman , Y. Tom Tang , Preeti G. Lal , Narinder K. Chawla , Jennifer L. Policky
发明人: Henry Yue , Danniel B. Nguyen , Catherine M. Tribouley , Olga Bandman , Y. Tom Tang , Preeti G. Lal , Narinder K. Chawla , Jennifer L. Policky
IPC分类号: G01N33/50 , A61K38/00 , A61K45/00 , A61P25/00 , A61P35/00 , A61P37/00 , A61P43/00 , C07K14/47 , C07K16/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/02 , C12N15/09 , C12P21/02 , C12P21/08 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N33/566 , C07H21/04
CPC分类号: C07K14/47 , A01K2217/05
摘要: The invention provides human microtubule-associated proteins and tubulins (MICAPTUB) and polynucleotides which identify and encode MICAPTUB. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of MICAPTUB.
摘要翻译: 本发明提供了人微管相关蛋白和微管蛋白(MICAPTUB)和识别和编码MICAPTUB的多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与MICAPTUB的异常表达相关的疾病的方法。
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公开(公告)号:US07112426B2
公开(公告)日:2006-09-26
申请号:US10288798
申请日:2002-11-01
申请人: Olga Bandman , Danniel B Nguyen , Narinder K Chawla , April J A Hafalia , Monique G Yao , Ameena R Gandhi , Rajagopal Gururajan , Li Ding , Chandra S Arvizu , Henry Yue , Mariah R Baughn , Catherine M Tribouley , Michael B Thornton , Vicki S Elliott , Yan Lu , Craig H Ison , Janice K Au-Young , Y Tom Tang , Yalda Azimzai , John D Burrill , Gregory A Marcus , Kurt A Zingler , Dyung Aina M Lu , Preeti G Lai , Jayalaxmi Ramkumar , Bridget A Warren , Liam Kearney , Jennifer L Policky , Kavitha Thangavelu , Neil Burford
发明人: Olga Bandman , Danniel B Nguyen , Narinder K Chawla , April J A Hafalia , Monique G Yao , Ameena R Gandhi , Rajagopal Gururajan , Li Ding , Chandra S Arvizu , Henry Yue , Mariah R Baughn , Catherine M Tribouley , Michael B Thornton , Vicki S Elliott , Yan Lu , Craig H Ison , Janice K Au-Young , Y Tom Tang , Yalda Azimzai , John D Burrill , Gregory A Marcus , Kurt A Zingler , Dyung Aina M Lu , Preeti G Lai , Jayalaxmi Ramkumar , Bridget A Warren , Liam Kearney , Jennifer L Policky , Kavitha Thangavelu , Neil Burford
CPC分类号: C07K14/4702 , A01K2217/05
摘要: The invention provides human human kinases (PKIN) and polynucleotides which identify and encode PKIN. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of PKIN.
摘要翻译: 本发明提供人类人类激酶(PKIN)和识别和编码PKIN的多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与PKIN的异常表达相关的障碍的方法。
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公开(公告)号:US06927056B2
公开(公告)日:2005-08-09
申请号:US10363937
申请日:2001-09-06
申请人: Stephen Todd , Angelo M. Delegeane , Ameena R. Gandhi , Danniel B. Nguyen , April J. A. Hafalia , Liam Kearney , Yan Lu , Ernestine A. Lee , Narinder K. Chawla , Debopriya Das , Chandra S. Arvizu , Monique G. Yao , Deborah A. Kallick , Vicki S. Elliott , Li Ding , Henry Yue , Roopa M. Reddy , Dyung Aina M. Lu , Jayalaxmi Ramkumar , Junming Yang , Catherine M. Tribouley , Neil Burford , Mariah R. Baughn , Preeti G. Lal , Mark L. Borowsky , Farrah A. Khan , Rajagopal Gururajan , Y. Tom Tang , Janice K. Au-Young , Bridget A. Warren , Roberto Hernandez , Brendan M. Duggan
发明人: Stephen Todd , Angelo M. Delegeane , Ameena R. Gandhi , Danniel B. Nguyen , April J. A. Hafalia , Liam Kearney , Yan Lu , Ernestine A. Lee , Narinder K. Chawla , Debopriya Das , Chandra S. Arvizu , Monique G. Yao , Deborah A. Kallick , Vicki S. Elliott , Li Ding , Henry Yue , Roopa M. Reddy , Dyung Aina M. Lu , Jayalaxmi Ramkumar , Junming Yang , Catherine M. Tribouley , Neil Burford , Mariah R. Baughn , Preeti G. Lal , Mark L. Borowsky , Farrah A. Khan , Rajagopal Gururajan , Y. Tom Tang , Janice K. Au-Young , Bridget A. Warren , Roberto Hernandez , Brendan M. Duggan
IPC分类号: A01K67/00 , C07H21/04 , C12N9/64 , C12N15/09 , C12P21/06 , C12Q1/68 , C12N1/20 , C12N15/00 , C12N15/63
CPC分类号: C12N9/6421 , A01K2217/05 , A01K2217/075 , C07H21/04 , C12N9/6472 , C12Q1/6837 , C12Q1/6883 , C12Q2600/156 , C12Q2600/158 , Y02A50/52
摘要: The invention provides a human cysteine proteases and polynucleotides which encode those proteases. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists, as well as methods for diagnosing, treating, or preventing disorders associated with aberrant expression of cysteine proteases.
摘要翻译: 本发明提供编码这些蛋白酶的人半胱氨酸蛋白酶和多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂,以及用于诊断,治疗或预防与半胱氨酸蛋白酶异常表达相关的紊乱的方法。
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公开(公告)号:US07029897B2
公开(公告)日:2006-04-18
申请号:US10433794
申请日:2001-12-04
申请人: Henry Yue , Li Ding , Preeti G. Lal , Jennifer A. Griffin , Rajagopal Gururajan , Mariah R. Baughn , Craig H. Ison , Jayalaxmi Ramkumar , Catherine M. Tribouley , Anita Swarnakar , Neil Burford , Olga Bandman , Michael Thornton , Farrah A. Khan , Narinder K. Chawla , Danniel B. Nguyen , Vicki S. Elliott , Yuming Xu , Yan Lu , April J. A. Hafalia , Monique G. Yao , Ameena R. Gandhi , Chandra S. Arvizu , Ian J. Forsythe
发明人: Henry Yue , Li Ding , Preeti G. Lal , Jennifer A. Griffin , Rajagopal Gururajan , Mariah R. Baughn , Craig H. Ison , Jayalaxmi Ramkumar , Catherine M. Tribouley , Anita Swarnakar , Neil Burford , Olga Bandman , Michael Thornton , Farrah A. Khan , Narinder K. Chawla , Danniel B. Nguyen , Vicki S. Elliott , Yuming Xu , Yan Lu , April J. A. Hafalia , Monique G. Yao , Ameena R. Gandhi , Chandra S. Arvizu , Ian J. Forsythe
CPC分类号: C12N9/1205 , C07H21/04 , C12N9/16
摘要: The invention provides human kinases and phosphatases (KAP) and polnucleotides which identify and encode KAP. The invention also provides expresson vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of KAP.
摘要翻译: 本发明提供鉴定和编码KAP的人激酶和磷酸酶(KAP)和核苷酸。 本发明还提供了表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与KAP的异常表达相关的疾病的方法。
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公开(公告)号:US20090274680A1
公开(公告)日:2009-11-05
申请号:US12076827
申请日:2008-03-24
申请人: Preeti Lal , Monique G. Yao , Henry Yue , Ameena R. Gandhi , Farrah A. Khan , Y. Tom Tang , Danniel B. Nguyen , Jennifer L. Policky , Debopriya Das , Jennifer L. Hillman , Narinder Walia , April J. A. Hafalia , Catherine M. Tribouley
发明人: Preeti Lal , Monique G. Yao , Henry Yue , Ameena R. Gandhi , Farrah A. Khan , Y. Tom Tang , Danniel B. Nguyen , Jennifer L. Policky , Debopriya Das , Jennifer L. Hillman , Narinder Walia , April J. A. Hafalia , Catherine M. Tribouley
IPC分类号: A61K38/46 , C07K14/00 , A61K38/16 , C12N9/16 , C12P21/00 , C07K16/00 , A61P35/00 , A61P29/00 , A61P37/06 , A61P9/00 , A61P1/00
CPC分类号: C12N15/52 , A61K38/00 , C07K14/47 , C07K16/40 , C12Q1/6883
摘要: The invention provides human lipid metabolism enzymes (LME) and polynucleotides which identify and encode LME. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of LME.
摘要翻译: 本发明提供了人类脂质代谢酶(LME)和识别和编码LME的多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与LME异常表达相关的紊乱的方法。
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公开(公告)号:US07368270B2
公开(公告)日:2008-05-06
申请号:US11275596
申请日:2006-01-18
申请人: Preeti Lal , Monique G. Yao , Henry Yue , Ameena R. Gandhi , Y. Tom Tang , Farrah A. Khan , Danniel B. Nguyen , Jennifer L. Policky , Debopriya Das , Jennifer L. Hillman , Narinder K. Walia , April J. A. Hafalia , Catherine M. Tribouley
发明人: Preeti Lal , Monique G. Yao , Henry Yue , Ameena R. Gandhi , Y. Tom Tang , Farrah A. Khan , Danniel B. Nguyen , Jennifer L. Policky , Debopriya Das , Jennifer L. Hillman , Narinder K. Walia , April J. A. Hafalia , Catherine M. Tribouley
CPC分类号: C12N15/52 , A61K38/00 , C07K14/47 , C07K16/40 , C12Q1/6883
摘要: The invention provides human lipid metabolism enzymes (LME) and polynucleotides which identify and encode LME. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of LME.
摘要翻译: 本发明提供了人类脂质代谢酶(LME)和识别和编码LME的多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与LME异常表达相关的紊乱的方法。
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公开(公告)号:US20100099617A1
公开(公告)日:2010-04-22
申请号:US12585371
申请日:2009-09-14
申请人: Henry Yue , Monique G. Yao , Ameena R. Gandhi , Mariah R. Baughn , Anita Swarnakar , Narinder K. Chawla , Madhusudan M. Sanjanwala , Michael B. Thornton , Vicki S. Elliott , Yan Lu , Kimberly J. Gietzen , Neil Burford , Li Ding , April J. A. Hafalia , Y. Tom Tang , Olga Bandman , Bridget A. Warren , Cynthia D. Honchell , Dyung Aina M. Lu , Kavitha Thangavelu , Sally Lee , Yuming Xu , Junming Yang , Preeti G. Lal , Bao Tran , Craig H. Ison , Brendan M. Duggan , Stephanie K. Sapperstein
发明人: Henry Yue , Monique G. Yao , Ameena R. Gandhi , Mariah R. Baughn , Anita Swarnakar , Narinder K. Chawla , Madhusudan M. Sanjanwala , Michael B. Thornton , Vicki S. Elliott , Yan Lu , Kimberly J. Gietzen , Neil Burford , Li Ding , April J. A. Hafalia , Y. Tom Tang , Olga Bandman , Bridget A. Warren , Cynthia D. Honchell , Dyung Aina M. Lu , Kavitha Thangavelu , Sally Lee , Yuming Xu , Junming Yang , Preeti G. Lal , Bao Tran , Craig H. Ison , Brendan M. Duggan , Stephanie K. Sapperstein
IPC分类号: A61K38/16 , C07K14/00 , A61K38/22 , C07K14/575 , A61P35/00 , A61P29/00 , A61P37/00 , A61P25/00 , A61P9/00 , C12P21/02
CPC分类号: C12N15/1055 , A61K39/3955 , A61K47/64 , A61K47/643 , A61K2039/505 , C07K14/47 , C07K14/4711 , C07K14/4713 , C07K16/18 , C07K2317/24 , C07K2317/54 , C07K2317/55 , C07K2317/622 , C07K2317/75 , C07K2317/76 , G01N33/5023
摘要: The invention provides human secreted proteins (SECP) and polynucleotides which identify and encode SECP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of SECP.
摘要翻译: 本发明提供鉴定和编码SECP的人分泌蛋白(SECP)和多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与SECP异常表达相关的疾病的方法。
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公开(公告)号:US08153398B2
公开(公告)日:2012-04-10
申请号:US12457389
申请日:2009-06-09
申请人: Preeti G. Lal , Y. Tom Tang , Gina A. Gorgone Simone , Neil C. Corley , Karl J. Guegler , Mariah R. Baughn , Ingrid E. Akerblom , Janice K. Au-Young , Henry Yue , Chandra S. Arvizu , Roopa M. Reddy , Jennifer L. Hillman , Olga Bandman
发明人: Preeti G. Lal , Y. Tom Tang , Gina A. Gorgone Simone , Neil C. Corley , Karl J. Guegler , Mariah R. Baughn , Ingrid E. Akerblom , Janice K. Au-Young , Henry Yue , Chandra S. Arvizu , Roopa M. Reddy , Jennifer L. Hillman , Olga Bandman
CPC分类号: G01N33/57419 , A61K38/00 , A61K38/1709 , A61K39/3955 , A61K45/06 , C07K14/47 , C07K16/18 , C07K16/40 , C07K2317/76 , G01N2333/916
摘要: The invention provides human signal peptide-containing proteins (HSPP) and polynucleotides which identify and encode HSPP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of HSPP.
摘要翻译: 本发明提供了人信号肽肽蛋白(HSPP)和识别和编码HSPP的多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与HSPP表达相关的障碍的方法。
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公开(公告)号:US08716445B2
公开(公告)日:2014-05-06
申请号:US13397592
申请日:2012-02-15
申请人: Preeti G. Lal , Y. Tom Tang , Gina A. Gorgone Simone , Neil C. Corley , Karl J. Guegler , Mariah R. Baughn , Ingrid E. Akerblom , Janice K. Au-Young , Henry Yue , Chandra S. Arvizu , Roopa M. Reddy , Jennifer L. Hillman , Olga Bandman
发明人: Preeti G. Lal , Y. Tom Tang , Gina A. Gorgone Simone , Neil C. Corley , Karl J. Guegler , Mariah R. Baughn , Ingrid E. Akerblom , Janice K. Au-Young , Henry Yue , Chandra S. Arvizu , Roopa M. Reddy , Jennifer L. Hillman , Olga Bandman
CPC分类号: G01N33/57419 , A61K38/00 , A61K38/1709 , A61K39/3955 , A61K45/06 , C07K14/47 , C07K16/18 , C07K16/40 , C07K2317/76 , G01N2333/916
摘要: The invention provides human signal peptide-containing proteins (HSPP) and polynucleotides which identify and encode HSPP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of HSPP.
摘要翻译: 本发明提供了人信号肽肽蛋白(HSPP)和识别和编码HSPP的多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与HSPP表达相关的障碍的方法。
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公开(公告)号:US07608704B2
公开(公告)日:2009-10-27
申请号:US11378616
申请日:2006-03-20
申请人: Henry Yue , Monique G. Yao , Ameena R. Gandhi , Mariah R. Baughn , Anita Swarnakar , Narinder Chawla , Madhusudan M. Sanjanwala , Michael Thorton , Vicki S. Elliott , Yan Lu , Kimberly J. Gietzen , Neil Burford , Li Ding , April J. A. Hafalia , Y. Tom Tang , Olga Bandman , Bridget A. Warren , Cynthia D. Honchell , Dyung Aina M. Lu , Kavitha Thangavelu , Sally Lee , Yuming Xu , Junming Yang , Preeti G. Lal , Bao Tran , Craig H. Ison , Brendan M. Duggan , Stephanie K. Sapperstein
发明人: Henry Yue , Monique G. Yao , Ameena R. Gandhi , Mariah R. Baughn , Anita Swarnakar , Narinder Chawla , Madhusudan M. Sanjanwala , Michael Thorton , Vicki S. Elliott , Yan Lu , Kimberly J. Gietzen , Neil Burford , Li Ding , April J. A. Hafalia , Y. Tom Tang , Olga Bandman , Bridget A. Warren , Cynthia D. Honchell , Dyung Aina M. Lu , Kavitha Thangavelu , Sally Lee , Yuming Xu , Junming Yang , Preeti G. Lal , Bao Tran , Craig H. Ison , Brendan M. Duggan , Stephanie K. Sapperstein
CPC分类号: C12N15/1055 , A61K39/3955 , A61K47/64 , A61K47/643 , A61K2039/505 , C07K14/47 , C07K14/4711 , C07K14/4713 , C07K16/18 , C07K2317/24 , C07K2317/54 , C07K2317/55 , C07K2317/622 , C07K2317/75 , C07K2317/76 , G01N33/5023
摘要: The invention provides human secreted proteins (SECP) and polynucleotides which identify and encode SECP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of SECP.
摘要翻译: 本发明提供鉴定和编码SECP的人分泌蛋白(SECP)和多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与SECP异常表达相关的疾病的方法。
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