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51.发明授权公开(公告)号：US08216310B2
公开(公告)日：2012-07-10
申请号：US11864450
申请日：2007-09-28
申请人： Can B. Hu , Michael D. Lowery
发明人： Can B. Hu , Michael D. Lowery
IPC分类号： A61F2/16
CPC分类号： A61F2/16 , A61F2/15 , A61F2/1613 , A61F2002/1681 , A61F2002/1682 , A61F2250/0018 , A61L27/18 , A61L2430/16 , C08F230/08 , C08G77/20 , C08G77/70 , C08L83/04 , Y10T156/10
摘要： A polymeric material with a molecular response time that makes it suitable for use near fragile body tissues. The polymeric material is useful for both low modulus and high modulus applications thereby simplifying the multi-part polymeric article manufacturing process and creating better integrated multi-part polymeric articles. Cross-linked polymers with different moduli may be obtained utilizing the same or similar starting materials but modifying the amount of catalyst, the amount of cross-linking agent, and/or the amount of methyl vinyl cyclics.
摘要翻译： 具有分子响应时间的聚合材料，使其适合在脆弱的身体组织附近使用。 聚合物材料可用于低模量和高模量应用，从而简化了多部件聚合物制品的制造过程，并且形成了更好的集成的多部分聚合物制品。 具有不同模量的交联聚合物可以利用相同或相似的起始材料获得，但改变催化剂的量，交联剂的量和/或甲基乙烯基环状的量。
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公开(公告)号：US08215771B2
公开(公告)日：2012-07-10
申请号：US12839241
申请日：2010-07-19
申请人： Huawei Zhao
发明人： Huawei Zhao
IPC分类号： G02C7/02
CPC分类号： G02C7/04 , A61F2/1613 , A61F2/1637 , A61F2250/0053 , G02C7/028 , G02C7/041 , G02C7/045 , G02C2202/02
摘要： An intraocular lens for correcting or reducing the astigmatism of a cornea includes a pupil that is spatially divided into discrete zones, with each zone having a particular astigmatism magnitude and astigmatism orientation. In one embodiment, the zones all have the same astigmatism magnitude, which is equal and opposite the cornea astigmatism magnitude to within a particular tolerance, such as 0.25 diopters. In one embodiment, some or all of the zones all have different astigmatism orientations, with the angular separation between astigmatism orientations being on the order of the rotational misalignment tolerance of the lens to the cornea. The visual performance of such a lens deteriorates more slowly with rotational misalignment, when compared to a comparable lens having a uniform astigmatism orientation across its entire pupil, leading to more relaxed tolerances for a surgeon that implants the lens.
摘要翻译： 用于矫正或减少角膜散光的眼内透镜包括在空间上分成离散区域的瞳孔，每个区域具有特定的散光大小和像散取向。 在一个实施例中，这些区域都具有相同的散光大小，其等于和相反的角膜散光幅度在特定容限内，例如0.25屈光度。 在一个实施例中，一些或全部区域都具有不同的像散取向，像散取向之间的角度间隔在镜片与角膜的旋转不对准公差的数量级上。 当与其整个瞳孔具有均匀的散光取向的可比较的镜片相比时，这种镜片的视觉性能变得更慢，因为旋转未对准，导致植入镜片的外科医生的更宽松的公差。
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公开(公告)号：US08182088B2
公开(公告)日：2012-05-22
申请号：US13021498
申请日：2011-02-04
申请人： Sverker Norrby , Rolf Bergman
发明人： Sverker Norrby , Rolf Bergman
CPC分类号： A61F2/1613 , A61B3/0025 , A61B3/103 , A61B3/107
摘要： A system for providing an intraocular lens includes a processor and a computer readable memory. The computer readable memory is configured to communicate with the processor, the memory having stored therein at least one of: one or more ocular dimensions, and at least one predetermined refractive outcome. The memory further includes a sequence of instructions which, when executed by the processor, cause the processor to select an intraocular lens, select a power of an intraocular lens, or provide an intraocular lens. The sequence of instructions includes determining one or more dimensions of an eye. The instructions also include calculating, based on a mathematical relationship, a distance from an apex of a cornea of the eye to an apex or plane of the intraocular lens after insertion into the eye. The instructions further calculating an optical power of the intraocular lens suitable for providing a predetermined refractive outcome. The mathematical relationship includes an axial length of the eye, an anterior chamber depth of the natural crystalline lens, and a corneal radius of the eye, but is independent of a thickness of the natural crystalline lens.
摘要翻译： 用于提供眼内透镜的系统包括处理器和计算机可读存储器。 计算机可读存储器被配置为与处理器通信，其中存储有存储器中的至少一个：一个或多个眼睛尺寸和至少一个预定折射结果。 所述存储器还包括指令序列，当由所述处理器执行时，使所述处理器选择人工晶状体，选择人工晶状体的能量或提供眼内透镜。 指令序列包括确定眼睛的一个或多个维度。 说明书还包括基于数学关系计算在插入眼睛之后从眼睛的角膜的顶点到眼内透镜的顶点或平面的距离。 所述指令还计算适于提供预定屈光结果的眼内透镜的光焦度。 数学关系包括眼睛的轴向长度，天然晶状体的前房深度和眼睛的角膜半径，但是与天然晶状体的厚度无关。
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54.发明授权公开(公告)号：US07955704B2
公开(公告)日：2011-06-07
申请号：US12611639
申请日：2009-11-03
申请人： Michael D. Lowery , Laurent Hoffmann , Boris Kobrin , Romuald Nowak , Jeffrey Chinn , Richard Yi
发明人： Michael D. Lowery , Laurent Hoffmann , Boris Kobrin , Romuald Nowak , Jeffrey Chinn , Richard Yi
IPC分类号： A61F2/16
CPC分类号： B82Y30/00 , A61L27/34 , A61L29/085 , A61L31/10 , B82Y40/00 , Y10T428/261 , Y10T428/31667 , C08L71/02
摘要： An intraocular lens with a hydrophilic polymer coating composition and method of preparing same are provided. Specifically, a composition suitable for reducing tackiness in intraocular lenses is provided wherein an acrylic intraocular lens is treated by vapor deposition with an alkoxy silyl terminated polyethylene glycol polymer composition.
摘要翻译： 提供具有亲水性聚合物涂料组合物的眼内透镜及其制备方法。 具体地说，提供一种适用于降低人工晶状体粘合性的组合物，其中丙烯酸类眼内透镜用烷氧基甲硅烷基封端的聚乙二醇聚合物组合物气相沉积处理。
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公开(公告)号：US09918873B2
公开(公告)日：2018-03-20
申请号：US14509850
申请日：2014-10-08
发明人： Bruce Woodley , Javier Gonzalez
CPC分类号： A61F9/008 , A61B3/102 , A61F9/00804 , A61F9/00827 , A61F9/0084 , A61F2009/00851 , A61F2009/00855 , A61F2009/00882 , G01B9/02091
摘要： A laser system is calibrated with a tomography system capable of measuring locations of structure within an optically transmissive material such as a tissue of an eye. Alternatively or in combination, the tomography system can be used to track the location of the eye and adjust the treatment in response to one or more of the location or an orientation of the eye. In many embodiments, in situ calibration and tracking of an optically transmissive tissue structure such as an eye can be provided. The optically transmissive material may comprise one or more optically transmissive structures of the eye, or a non-ocular optically transmissive material such as a calibration gel in a container or an optically transmissive material of a machined part.
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公开(公告)号：US09849032B2
公开(公告)日：2017-12-26
申请号：US14191095
申请日：2014-02-26
发明人： Georg Schuele , Phillip Gooding, I
CPC分类号： A61F9/00804 , A61B3/1025 , A61B3/14 , A61F9/008 , A61F9/00802 , A61F9/00812 , A61F9/00836 , A61F2009/00846 , A61F2009/00855 , A61F2009/00868 , A61F2009/00872 , A61F2009/00889 , A61F2009/00897
摘要： An imaging system includes an eye interface device, a scanning assembly, a beam source, a free-floating mechanism, and a detection assembly. The eye interface device interfaces with an eye. The scanning assembly supports the eye interface device and scans a focal point of an electromagnetic radiation beam within the eye. The beam source generates the electromagnetic radiation beam. The free-floating mechanism supports the scanning assembly and accommodates movement of the eye and provides a variable optical path for the electronic radiation beam and a portion of the electronic radiation beam reflected from the focal point location. The variable optical path is disposed between the beam source and the scanner and has an optical path length that varies to accommodate movement of the eye. The detection assembly generates a signal indicative of intensity of a portion of the electromagnetic radiation beam reflected from the focal point location.
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公开(公告)号：US09833358B2
公开(公告)日：2017-12-05
申请号：US12987069
申请日：2011-01-07
申请人： Georg Schuele , Dan Andersen
发明人： Georg Schuele , Dan Andersen
IPC分类号： A61F9/008
CPC分类号： A61F9/008 , A61F9/00812 , A61F9/00827 , A61F9/00834 , A61F2009/00842 , A61F2009/00853 , A61F2009/0087 , A61F2009/00872 , A61F2009/00889
摘要： As shown in the drawings for purposes of illustration, a method and system for making physical modifications to intraocular targets is disclosed. In varying embodiments, the method and system disclosed herein provide many advantages over the current standard of care. Specifically, linear absorption facilitated photodecomposition and linear absorption facilitated plasma generation to modify intraocular tissues and synthetic intraocular lenses.
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公开(公告)号：US09823163B2
公开(公告)日：2017-11-21
申请号：US14878294
申请日：2015-10-08
申请人： AMO Groningen B.V.
发明人： Aixa Alarcon Heredia , Carmen Canovas Vidal , Robert Rosén , Hendrik A. Weeber , Patricia Ann Piers
CPC分类号： G01M11/0292 , G01M11/0235 , G06F19/00 , G16H50/50
摘要： A system and method of characterizing through-focus visual performance of an IOL using metrics based on an area under the modulation transfer function for different spatial frequencies at different defocus positions of the IOL. Also disclosed is a system and method of characterizing through-focus visual performance of an IOL using a metric based on an area under a cross-correlation coefficient for an image of a target acquired by the IOL at different defocus positions of the IOL.
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公开(公告)号：US09814621B2
公开(公告)日：2017-11-14
申请号：US15439593
申请日：2017-02-22
申请人： AMO Development, LLC
IPC分类号： A61F9/008
CPC分类号： A61F9/00814 , A61B2017/00057 , A61B2017/00154 , A61F9/008 , A61F9/00802 , A61F9/00817 , A61F2009/00844 , A61F2009/00846 , A61F2009/00848 , A61F2009/00872 , A61F2009/0088 , A61F2009/00882 , A61F2009/00885 , A61F2009/00897
摘要： Systems and methods for removing an epithelial layer disposed over a stromal layer in a cornea irradiate a region of the epithelial layer with a pulsed beam of ablative radiation. The ablative radiation is scanned to vary the location of the beam within the region in accordance with a pulse sequence. The pulse sequence is arranged to enhance optical feedback based on a tissue fluorescence of the epithelial layer. The penetration of the epithelial layer is detected in response to the optical feedback. The use of scanning with the pulse sequence arranged to enhance optical feedback allows large areas of the epithelium to be ablated such penetration of the epithelial layer can be detected.
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公开(公告)号：US09788939B2
公开(公告)日：2017-10-17
申请号：US15069352
申请日：2016-03-14
IPC分类号： A61F2/16
CPC分类号： A61F2/1691 , A61F2/1664 , A61F2/167 , A61F2/1678 , A61F2002/1683
摘要： A rear-loaded injector cartridge for an intraocular lens (IOL) having a proximal opening that provides a haptic slot. The haptic slot receives a leading haptic of an IOL loaded therein, and temporarily retains the leading haptic while the optic of the IOL is inserted into a holding area of the cartridge. As the optic passes by, the leading haptic folds over the top of the optic, on its anterior side. The length of the haptic retention slot is sufficient to maintain the leading haptic in its anteriorly folded position while the IOL remains in holding area, typically while the cartridge is mated with a handpiece of the injector. The cartridge also has a rear or proximal cut out which advantageously keys with a similarly-sized rail on the handpiece so that the cartridge cannot be inserted in the wrong way.
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