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    Endoprostheses
    51.
    发明授权
    Endoprostheses 失效
    内假体

    公开(公告)号：US08071156B2

    公开(公告)日：2011-12-06

    申请号：US12397509

    申请日：2009-03-04

    Applicant: Jan Weber ,  Torsten Scheuermann

    Inventor： Jan Weber ,  Torsten Scheuermann

    IPC: A61L33/00

    CPC classification number: A61L33/00 ,  A61L31/088 ,  A61L31/14 ,  A61L31/146

    Abstract: A hydrophilic ceramic coating is formed on an endoprosthesis preform. The hydrophilic ceramic coating is porous and can store nano-sized drug particles.

    Abstract translation: 在内置假体预成型件上形成亲水性陶瓷涂层。 亲水陶瓷涂层是多孔的，可以存储纳米尺寸的药物颗粒。

    THIN PROFILE CONDUCTOR ASSEMBLY FOR MEDICAL DEVICE LEADS
    53.
    发明申请
    THIN PROFILE CONDUCTOR ASSEMBLY FOR MEDICAL DEVICE LEADS 有权
    医疗设备导线薄型导线器总成

    公开(公告)号：US20100234929A1

    公开(公告)日：2010-09-16

    申请号：US12704939

    申请日：2010-02-12

    Applicant: Torsten Scheuermann

    Inventor： Torsten Scheuermann

    IPC: A61N1/02 ,  H01B7/00 ,  B05D5/12

    CPC classification number: A61N1/056 ,  A61N1/086

    Abstract: A medical device lead includes a thin profile conductor assembly. A proximal connector includes a proximal end that is configured to couple the lead to a pulse generator. An insulative lead body extends distally from the proximal connector. The conductor assembly extends distally from the proximal end within the lead body and includes a non-conductive tubular core member that defines a lumen, an outer insulative layer, and a multilayer conductor between the tubular core member and the outer insulative layer. The multilayer conductor is electrically connected to the proximal connector and includes a first conductive layer adjacent to the tubular core member and a second conductive layer adjacent to the first conductive layer opposite the tubular core member. A conductivity of the second conductive layer is greater than a conductivity of the first conductive layer.

    Abstract translation: 医疗器械引线包括薄型导体组件。 近端连接器包括被配置为将引线耦合到脉冲发生器的近端。 绝缘引线体从近端连接器向远侧延伸。 导体组件从引线主体内的近端向远侧延伸，并且包括在管芯和外绝缘层之间限定内腔，外绝缘层和多层导体的非导电管状芯构件。 所述多层导体电连接到所述近端连接器，并且包括与所述管状芯部件相邻的第一导电层和与所述管状芯部件相对的所述第一导电层相邻的第二导电层。 第二导电层的导电率大于第一导电层的导电率。

    MEDICAL DEVICES HAVING A COATING OF INORGANIC MATERIAL
    54.
    发明申请
    MEDICAL DEVICES HAVING A COATING OF INORGANIC MATERIAL 有权
    具有无机材料涂层的医疗装置

    公开(公告)号：US20090264975A1

    公开(公告)日：2009-10-22

    申请号：US12425791

    申请日：2009-04-17

    Applicant: Aiden FLANAGAN ,  John KILCOOLEY ,  Tim O'CONNOR ,  Barry O'BRIEN ,  Dominique SEIDEL ,  Michael KUEHLING ,  Torsten SCHEUERMANN ,  Jan WEBER

    Inventor： Aiden FLANAGAN ,  John KILCOOLEY ,  Tim O'CONNOR ,  Barry O'BRIEN ,  Dominique SEIDEL ,  Michael KUEHLING ,  Torsten SCHEUERMANN ,  Jan WEBER

    IPC: A61F2/82 ,  A61L33/00

    CPC classification number: A61L29/10 ,  A61L29/16 ,  A61L31/082 ,  A61L31/16 ,  A61L2300/602 ,  A61L2300/61

    Abstract: In one aspect, a medical device has a first configuration and a second configuration, a reservoir containing a therapeutic agent, and a barrier layer disposed over the reservoir, wherein the barrier layer comprises an inorganic material. In another aspect, a medical device has a reservoir containing a therapeutic agent, a barrier layer disposed over the reservoir, wherein the barrier layer comprises an inorganic material, and a swellable material disposed between the barrier layer and a surface of the medical device, wherein the swellable material is a material that swells upon exposure to an aqueous environment. In yet another aspect, a medical device has a multi-layered coating having alternating reservoir layers and barrier layers, and a plurality of excavated regions penetrating through at least a partial thickness of the multi-layered coating. In yet another aspect, a medical device has a polymer layer comprising a block co-polymer, wherein the polymer layer contains a therapeutic agent, and a barrier layer disposed over the polymer layer, wherein the barrier layer comprises an inorganic material, and wherein the barrier layer has a plurality of discontinuities. Methods of forming coatings on medical devices and methods of delivering therapeutic agents to body sites are also disclosed.

    Abstract translation: 在一个方面，医疗装置具有第一构造和第二构造，包含治疗剂的贮存器和设置在贮存器上方的阻挡层，其中阻挡层包括无机材料。 在另一方面，医疗装置具有容纳治疗剂的储存器，设置在贮存器上方的阻挡层，其中所述阻挡层包括无机材料，以及设置在所述阻挡层和所述医疗装置的表面之间的可溶胀材料，其中 可膨胀材料是暴露于含水环境时膨胀的材料。 在另一方面，医疗装置具有多层涂层，其具有交替的储层和阻挡层，以及穿透多层涂层的至少部分厚度的多个挖掘区域。 在另一方面，医疗装置具有包含嵌段共聚物的聚合物层，其中聚合物层含有治疗剂，以及设置在聚合物层上的阻挡层，其中阻挡层包含无机材料，其中， 阻挡层具有多个不连续性。 还公开了在医疗装置上形成涂层的方法和将治疗剂递送到身体部位的方法。

    Metal stent with surface layer of noble metal oxide and method of fabrication
    55.
    发明授权
    Metal stent with surface layer of noble metal oxide and method of fabrication 失效
    具有贵金属氧化物表面层的金属支架及其制造方法

    公开(公告)号：US07582112B2

    公开(公告)日：2009-09-01

    申请号：US11952624

    申请日：2007-12-07

    Applicant: Torsten Scheuermann ,  Lutz Stehling

    Inventor： Torsten Scheuermann ,  Lutz Stehling

    IPC: A61F2/06 ,  A61F2/24

    CPC classification number: A61L31/022 ,  A61F2/91 ,  A61F2/915 ,  A61F2002/91541 ,  A61F2002/91558 ,  A61F2310/00598 ,  A61L31/088 ,  A61L31/18

    Abstract: In a process for producing a biocompatible stent, a tubular substrate of the stent adapted for diametric expansion has a layer of a noble metal oxide formed over at least the outer surface of greater diameter of the substrate, the substrate being composed of a metal or an alloy thereof that is non-noble or less-noble than the layer's noble metal. An interface region adapted to prevent corrosion and to provide a firm bond between the surface of the substrate and the noble metal oxide layer is established, at least in part, by forming the noble metal oxide layer with a progressively varying concentration of noble metal-to-oxide with depth of the layer such that a surface of pure noble metal and negligible oxide of the layer is in closest proximity to the surface of the substrate. In one embodiment of the process, the interface region is established by forming the surface of pure noble metal and negligible oxide thereof in direct contact with the metal or alloy of the substrate surface. In another, the interface region is established by first creating an oxide of the substrate metal or alloy thereof at the substrate surface, and then forming the noble metal oxide layer as above, but in contact with the substrate metal or alloy oxide. Alternatively, the noble metal oxide layer has no progressively varying concentration but simply overlies an oxide of the substrate metal or alloy.

    Abstract translation: 在制造生物相容性支架的方法中，适用于直径膨胀的支架的管状基底具有至少在基底的较大直径的外表面上形成的贵金属氧化物层，该基底由金属或 它的合金是非贵重的或比贵金属低贵的贵金属。 至少部分地通过以逐渐变化的贵金属浓度形成贵金属氧化物层，从而建立适于防止腐蚀并在衬底表面和贵金属氧化物层之间提供牢固结合的界面区域 - 至少 氧化物，其层的深度使得纯贵金属的表面和该层的可忽略的氧化物最接近衬底的表面。 在该方法的一个实施方案中，通过形成纯金属的表面和与基底表面的金属或合金直接接触的可忽略的氧化物的表面来建立界面区域。 另一方面，通过首先在基板表面产生基板金属或其合金的氧化物，然后如上所述形成贵金属氧化物层，但与基板金属或合金氧化物接触来建立界面区域。 或者，贵金属氧化物层的浓度没有逐渐变化，而是简单地覆盖基板金属或合金的氧化物。

    Resonator with adjustable capacitance for medical device
    60.
    发明申请
    Resonator with adjustable capacitance for medical device 失效
    用于医疗设备的可调电容谐振器

    公开(公告)号：US20070106151A1

    公开(公告)日：2007-05-10

    申请号：US11270417

    申请日：2005-11-09

    Applicant: Torsten Scheuermann

    Inventor： Torsten Scheuermann

    IPC: A61B5/05

    CPC classification number: G01R33/286 ,  G01R33/3628

    Abstract: Systems and methods for a resonator with an adjustable capacitance for a medical device. In one embodiment, a resonator system includes a resonator device with an LC resonator circuit that has an adjustable capacitance, an inductor coil in series with the adjustable capacitance, and an adjustable capacitance control that can control the adjustable capacitance to obtain different particular capacitance values. This embodiment also includes a medical device, positioned with the resonator device, so that at least a portion of the inductor coil surrounds a space that is surrounded by at least a portion of the medical device.

    Abstract translation: 用于医疗设备具有可调电容的谐振器的系统和方法。 在一个实施例中，谐振器系统包括具有可调电容的LC谐振器电路的谐振器装置，与可调电容串联的电感线圈，以及可调节的电容控制，其可以控制可调电容以获得不同的特定电容值。 该实施例还包括与谐振器装置一起定位的医疗装置，使得电感线圈的至少一部分围绕由医疗装置的至少一部分包围的空间。

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