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123 条记录 (耗时 0.044 秒)

    Batch filtration system for preparation of sterile fluid for renal replacement therapy
    52.
    发明授权
    Batch filtration system for preparation of sterile fluid for renal replacement therapy 有权
    用于制备用于肾替代治疗的无菌液体的分批过滤系统

    公开(公告)号：US07749393B2

    公开(公告)日：2010-07-06

    申请号：US12434246

    申请日：2009-05-01

    申请人： James M. Brugger ,  Jeffrey H. Burbank ,  Brian C. Green

    发明人： James M. Brugger ,  Jeffrey H. Burbank ,  Brian C. Green

    IPC分类号： B01D61/26 ,  B01D61/30

    CPC分类号： A61M1/1656 ,  A61M1/14 ,  A61M1/166 ,  A61M1/167 ,  A61M1/1672 ,  A61M1/1674 ,  A61M1/28 ,  A61M1/288 ,  A61M1/3462 ,  A61M2205/12 ,  C02F1/44

    摘要： A method and device for blood treatments that use fluids such as dialysate and replacement fluid for renal replacement therapy. In an embodiment, fluid is passed either by pump or passively by gravity feed, through a microporous sterilization filter from a fluid source to a replacement fluid container. The latter forms a batch that may be used during treatment. The advantage of forming the batch before treatment is that the rate of filtering needn't match the rate of consumption during treatment. As a result, the sterilization filter can have a small capacity. In another embodiment, a filter is placed immediately prior to the point at which the sterile fluid is consumed by the treatment process. The latter may be used in combination with the former embodiment as a last-chance guarantee of sterility and/or that the fluid is free of air bubbles. It may also be used as the primary means of sterile-filtration.

    摘要翻译： 用于血液处理的方法和装置，其使用诸如透析液和替代液的流体用于肾替代治疗。 在一个实施例中，流体通过泵或被动地通过重力进料通过微孔灭菌过滤器从流体源传递到替换流体容器。 后者形成可在治疗期间使用的批次。 在处理之前形成批次的优点是过滤速率与处理过程中的消耗速率不一致。 结果，灭菌过滤器可以具有小容量。 在另一个实施方案中，过滤器被立即放置在无菌流体被处理过程消耗的点之前。 后者可以与前一个实施方案组合使用，作为不育的最后机会保证和/或流体没有气泡。 它也可以用作无菌过滤的主要手段。

    Filtration System for Preparation of Fluids for Medical Applications
    53.
    发明申请
    Filtration System for Preparation of Fluids for Medical Applications 有权
    用于医疗应用流体的过滤系统

    公开(公告)号：US20080230450A1

    公开(公告)日：2008-09-25

    申请号：US11813472

    申请日：2006-01-09

    申请人： Jeffrey H. Burbank ,  Dennis M. Treu ,  Gotz Friederichs ,  Brian C. Green ,  Christopher S. McDowell ,  James M. Brugger

    发明人： Jeffrey H. Burbank ,  Dennis M. Treu ,  Gotz Friederichs ,  Brian C. Green ,  Christopher S. McDowell ,  James M. Brugger

    IPC分类号： B01D35/143 ,  A61M1/16

    CPC分类号： A61M1/1656 ,  A61M1/1668 ,  A61M1/167 ,  A61M1/28 ,  A61M1/288 ,  A61M2205/12

    摘要： Systems, methods, and devices for preparation of water for various uses including blood treatment are described. In embodiments, fluid is passed either by pump or passively by gravity feed, through various filtration elements from a fluid source to a treatment fluid container The latter forms a batch that may be used during treatment. Methods and systems for creating multiple-treatment batches are described. Advantages of creating a multitreatment batch include the fact that the burden of treatment preparation can be reduced and the timing of the preparation of the batch can be independent of the treatment time. As described, there are various trade-offs and concerns with this approach which are addressed by the inventive embodiments.

    摘要翻译： 描述了用于制备包括血液处理在内的各种用途的水的系统，方法和装置。 在实施例中，流体通过泵或被动地通过重力进料通过各种过滤元件从流体源传递到处理流体容器。后者形成可在处理期间使用的批次。 描述了用于创建多个处理批次的方法和系统。 创建多处理批次的优点包括可以减少处理制剂的负担并且批次的制备时间可以独立于处理时间的事实。 如上所述，本发明实施例解决了这种方法的各种权衡和关切。

    Methods and Devices for Rendering Different Types of Patient Access Devices Compatible with Different Types of Tubing Sets
    54.
    发明申请
    Methods and Devices for Rendering Different Types of Patient Access Devices Compatible with Different Types of Tubing Sets 审中-公开
    用于渲染不同类型的患者接入设备的方法和设备兼容不同类型的管道组

    公开(公告)号：US20080228125A1

    公开(公告)日：2008-09-18

    申请号：US12128547

    申请日：2008-05-28

    申请人： James M. Brugger ,  Jeffrey H. Burbank ,  David S. Utterberg

    发明人： James M. Brugger ,  Jeffrey H. Burbank ,  David S. Utterberg

    IPC分类号： A61M1/14

    CPC分类号： A61M39/0208 ,  A61M1/16 ,  A61M1/28 ,  A61M1/285 ,  A61M1/288 ,  A61M1/3621 ,  A61M39/10 ,  A61M2039/0238 ,  A61M2039/1094 ,  A61M2205/3334 ,  A61M2205/6045

    摘要： In general, this invention relates to methods and devices for introducing and/or draining fluids into and/or from a patient's body. Methods and devices are provided for rendering conventional tubing sets, or fluid flow sets, which are normally coupleable with only specific complementary patient access devices, compatible with other access devices also. In accordance with one aspect of the invention, methods and devices are provided which render conventional extracorporeal tubing sets to be interchangeably connectable with other specific transcutaneous catheters. In yet another aspect of the invention, non-conventional tubing sets and corresponding non-conventional access devices for use in hemodialysis, or hemofiltration, are provided such that specific tubing sets and access devices can be used interchangeably.

    摘要翻译： 通常，本发明涉及用于将流体引入和/或排出患者体内和/或从患者身体引入和/或排出流体的方法和装置。 提供了用于渲染常规管组或流体流动装置的方法和装置，其通常仅与特定补充的患者进入装置耦合，也可与其他进入装置兼容。 根据本发明的一个方面，提供了使传统的体外管组与其它特定经皮导管可互换连接的方法和装置。 在本发明的另一方面，提供了用于血液透析或血液滤过的非常规管组和相应的非常规进入装置，使得特定的管组和接入装置可以互换使用。

    Fluid processing apparatus
    55.
    发明授权
    Fluid processing apparatus 有权
    流体处理装置

    公开(公告)号：US07226538B2

    公开(公告)日：2007-06-05

    申请号：US10772888

    申请日：2004-02-04

    申请人： James M. Brugger ,  Dennis M. Treu

    发明人： James M. Brugger ,  Dennis M. Treu

    IPC分类号： B01D61/00 ,  B01D36/00 ,  A61M37/00 ,  A61M39/00 ,  A61M39/10 ,  B01D61/30

    CPC分类号： A61M1/3643 ,  A61M1/288 ,  A61M1/3462 ,  A61M1/3468 ,  A61M1/3644 ,  A61M1/3646

    摘要： Systems and methods handle air and rinsing fluid during fluid processing. The systems and methods eliminate air from a fluid processing system prior to, during, and after use. The systems and methods provide a connector assembly for establishing fluid flow from a fluid source. The connector assembly has discrete first and second passages that prevent communication between the fluid in first passage and the fluid in the second passage. Prior to system use, the connector assembly may be utilized in a priming function to remove residual air from a fluid circuit prior to use. The connector assembly may also be utilized after use to perform a rinse-back function.

    摘要翻译： 系统和方法在流体处理过程中处理空气和冲洗液。 系统和方法在使用之前，期间和之后都从流体处理系统中排除空气。 这些系统和方法提供了用于建立来自流体源的流体流动的连接器组件。 连接器组件具有分离的第一和第二通道，其防止第一通道中的流体和第二通道中的流体之间的连通。 在系统使用之前，连接器组件可用于起动功能，以在使用之前从流体回路中除去残余空气。 连接器组件也可以在使用之后用于执行冲洗功能。

    Method and apparatus for leak detection in a fluid line
    56.
    发明授权
    Method and apparatus for leak detection in a fluid line 有权
    流体管路中泄漏检测的方法和装置

    公开(公告)号：US06572576B2

    公开(公告)日：2003-06-03

    申请号：US09900362

    申请日：2001-07-07

    申请人： James M. Brugger ,  Jeffrey H. Burbank ,  Dennis M. Treu

    发明人： James M. Brugger ,  Jeffrey H. Burbank ,  Dennis M. Treu

    IPC分类号： A61M3700

    CPC分类号： A61M1/3626 ,  A61M1/3656 ,  A61M2205/13

    摘要： One of the most significant safety concerns in the automation of extracorporeal blood treatments such as dialysis is the risk of blood leakage. Such systems draw blood at such a high rate that a loss of integrity in the blood circuit can be catastrophic. The most reliable leak detection method known is the detection of infiltrated air in a blood line, but this only works in blood lines under negative pressure. According to the invention, a leak detector for return lines is provided by periodically generating a negative pressure, which may be brief or at a 50% duty cycle, in the blood return line to draw air into it and thereby reveal the leaks using an air sensor. Although the return line is ordinarily under positive pressure, during the negative pressure cycle, the blood return line draws air through any leaks or disconnects. If air is detected, the system is shut down and an alarm generated.

    摘要翻译： 体外血液治疗如透析自动化中最重要的安全问题之一是出现血液渗漏的风险。 这样的系统以如此高的速度吸取血液，使得血液回路中完整性的丧失可能是灾难性的。 已知的最可靠的泄漏检测方法是检测血液中的渗透空气，但这仅在负压下的血液系统中起作用。 根据本发明，通过在血液回流管线周期性地产生负压（可以是短暂的或占空比为50％）来提供返回管线的泄漏检测器，以将空气吸入其中，从而利用空气泄露泄漏 传感器。 虽然返回线通常处于正压力下，但是在负压循环期间，血液回流管路通过任何泄漏或断开线吸入空气。 如果检测到空气，则系统关闭并产生报警。

    Methods and systems for establishing vascular access
    58.
    发明授权
    Methods and systems for establishing vascular access 失效
    建立血管通路的方法和系统

    公开(公告)号：US5931829A

    公开(公告)日：1999-08-03

    申请号：US856641

    申请日：1997-05-15

    申请人： Jeffrey H. Burbank ,  James M. Brugger ,  Charles D. Finch ,  Gerald Beathard ,  George W. Buffaloe

    发明人： Jeffrey H. Burbank ,  James M. Brugger ,  Charles D. Finch ,  Gerald Beathard ,  George W. Buffaloe

    IPC分类号： A61M1/36 ,  A61M5/158 ,  A61M25/00 ,  A61M39/02 ,  A61M31/00

    CPC分类号： A61M1/3653 ,  A61M39/0208 ,  A61M5/158 ,  A61M2005/1581 ,  A61M2205/195 ,  A61M25/0023

    摘要： A body lumen access system comprises a distal access cannula and a proximal access cannula. The distal access cannula is attached to or within the body lumen and the proximal access cannula is attached to an implantable port or is transcutaneously positioned and attached to a luer or other external connector. The distal and proximal access cannulas are usually implanted separately, cut to length, and attached at a subcutaneous junction location. Preferably, the proximal access cannula has a larger lumen diameter than that of the distal access cannula in order to reduce flow resistance within the cannula system. In some cases the distal and proximal access cannulas may be formed integrally.

    摘要翻译： 体腔通道系统包括远端进入插管和近端通路套管。 远端进入插管附接到体腔内或体腔内，并且近侧进入插管附接到可植入端口或经皮定位并附接到鲁尔或其它外部连接器。 远端和近端通道插管通常单独植入，切割长度，并连接在皮下接合处。 优选地，近侧通路插管具有比远侧进入插管更大的内腔直径，以便减小套管系统内的流动阻力。 在一些情况下，远端和近侧通路插管可以一体形成。