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公开(公告)号：US20140128576A1
公开(公告)日：2014-05-08
申请号：US14068670
申请日：2013-10-31
Applicant: Janssen Biotech, Inc.
Inventor： Jacqueline Benson , Mark Cunningham , Cynthia Duchala , Jill M. Giles-Komar , Jinquan Luo , Michael A. Rycyzyn , Raymond Sweet
IPC: C07K16/24
CPC classification number: A61K39/3955 , A61K39/00 , A61K45/06 , A61K2039/505 , A61K2039/55527 , A61K2039/55544 , C07K16/244 , C07K2317/30 , C07K2317/33 , C07K2317/34 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C07K2319/55 , G01N33/6869 , G01N2333/54 , Y02A50/386 , Y02A50/401 , Y02A50/41 , Y02A50/412 , Y02A50/55 , Y02A50/57 , Y02A50/58
Abstract: An anti-IL-23 antibody, including isolated nucleic acids that encode at least one anti-IL-23 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.
Abstract translation: 抗IL-23抗体，包括编码至少一种抗IL-23抗体，载体，宿主细胞，转基因动物或植物的分离的核酸及其制备和使用的方法具有诊断和/或治疗组合物中的应用 ，方法和设备。
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公开(公告)号：US20140093508A1
公开(公告)日：2014-04-03
申请号：US13973187
申请日：2013-08-22
Applicant: Janssen Biotech, Inc.
Inventor： Mark Cunningham , Yiqing Feng , Katharine Heeringa , Jinquan Luo , Robert Rauchenberger , Mark Rutz , Lani San Mateo , Robert Sarisky , Raymond Sweet , Fang Teng , Alexey Teplyakov , Sheng-Jiun Wu
IPC: C07K16/28
CPC classification number: C07K16/2896 , A61K39/39533 , A61K39/3955 , A61K2039/505 , C07H21/04 , C07K14/705 , C07K16/18 , C07K16/28 , C07K16/2863 , C07K2317/21 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/51 , C07K2317/515 , C07K2317/52 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C07K2317/94 , C12N5/10 , C12N5/12 , C12N15/117 , C12N15/63 , C12N2310/17 , A61K39/00 , A61K2300/00
Abstract: Toll Like Receptor 3 (TLR3) antibody antagonists, polynucleotides encoding TLR3 antibody antagonists or fragments thereof, and methods of making and using the foregoing are disclosed.
Abstract translation: 公开了Toll样受体3（TLR3）抗体拮抗剂，编码TLR3抗体拮抗剂或其片段的多核苷酸，以及制备和使用前述物质的方法。
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公开(公告)号：US12084501B2
公开(公告)日：2024-09-10
申请号：US17701764
申请日：2022-03-23
Applicant: Janssen Biotech, Inc.
Inventor： Adam Zwolak , Raymond Brittingham , Scott R. Brodeur , Rajkumar Ganesan , Sherry Lynn La Porte , Jinquan Luo , Fang Yi , Colleen M. Kane , Triveni K. Bhatt
CPC classification number: C07K16/2809 , C07K16/468 , C12N15/85 , A61K2039/507 , C07K2317/31 , C07K2317/55 , C07K2317/622
Abstract: The disclosure provides antigen binding domains that bind cluster of differentiation 3 (CD3) protein, comprising the antigen binding domains that bind CD3ε, polynucleotides encoding them, vectors, host cells, methods of making and using them.
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54.发明授权公开(公告)号：US12071466B2
公开(公告)日：2024-08-27
申请号：US16936719
申请日：2020-07-23
Applicant: Janssen Biotech, Inc.
Inventor： Raymond Brittingham , Rajkumar Ganesan , Sherry La Porte , John T. Lee , Jinquan Luo , Theresa McDevitt , Fei Shen , Sanjaya Singh , Degang Song , Sathyadevi Venkataramani , Fang Yi , Yonghong Zhao
IPC: A61K35/17 , A61K38/00 , C07K14/705 , C07K14/725 , C07K16/40
CPC classification number: C07K14/7051 , A61K35/17 , C07K14/70517 , C07K14/70596 , C07K16/40 , A61K38/00 , C07K2317/53 , C07K2317/565 , C07K2317/622 , C07K2319/02 , C07K2319/03
Abstract: The present disclosure provides for chimeric antigen receptors (CARs) that specifically target a human Kallikrein-2 (hK2), and immunoresponsive cells comprising such CARs, for the treatment of cancer.
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55.发明公开公开(公告)号：US20240124583A1
公开(公告)日：2024-04-18
申请号：US18397711
申请日：2023-12-27
Applicant: Janssen Biotech, Inc.
Inventor： Rajkumar Ganesan , John Lee , Jinquan Luo , Theresa McDevitt , Fei Shen , Degang Song , Raymond Brittingham , Sathyadevi Venkataramani , Sanjaya Singh , Yonghong Zhao , Fang Yi , Sherry Lynn LaPorte
CPC classification number: C07K16/2809 , C07K16/34 , C07K2317/14 , C07K2317/31 , C07K2317/565
Abstract: Embodiments of the present invention provide isolated proteins comprising antigen binding domains that bind kallikrein related peptidase 2 (hK2), including monospecific and bispecific antibodies. Additional embodiments of the invention provide polynucleotides encoding the hk2-specific proteins, vectors, host cells, and methods of making and using them.
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Patent Agency Ranking
公开(公告)号：US11746161B2
公开(公告)日：2023-09-05
申请号：US17125263
申请日：2020-12-17
Applicant: Janssen Biotech, Inc.
Inventor： Qiang Chen , Suzanne Cole , Karen Duffy , Yanxia Guo , Debra Gardner , Damon Hamel , Shannon Hitchcock , Ann Lacombe , Jinquan Luo , Ravi Malaviya , Yevgeniya Orlovsky , Pejman Soroosh , Melissa Swiecki , Deepti Wilkinson
CPC classification number: C07K16/40 , A61K39/3955 , A61P37/06 , C07K16/065 , C07K16/18 , C07K16/2818 , C12N15/00 , A61K2039/505 , A61K2039/57 , C07K2317/24 , C07K2317/33 , C07K2317/73 , C07K2317/732 , C07K2317/75 , C07K2317/76 , C07K2317/92
Abstract: Antibodies that specifically bind PD-1 or antigen binding fragments thereof, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing are useful in the treatment of an inflammatory or immune disorder.
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公开(公告)号：US20230040715A1
公开(公告)日：2023-02-09
申请号：US17701764
申请日：2022-03-23
Applicant: Janssen Biotech, Inc.
Inventor： Adam Zwolak , Raymond Brittingham , Scott R. Brodeur , Rajkumar Ganesan , Sherry Lynn La Porte , Jinquan Luo , Fang Yi , Colleen M. Kane , Triveni K. Bhatt
Abstract: The disclosure provides antigen binding domains that bind cluster of differentiation 3 (CD3) protein, comprising the antigen binding domains that bind CD3ε, polynucleotides encoding them, vectors, host cells, methods of making and using them.
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公开(公告)号：US10576150B2
公开(公告)日：2020-03-03
申请号：US16358775
申请日：2019-03-20
Applicant: Janssen Biotech, Inc.
Inventor： Jacqueline Benson , Mark Cunningham , Cynthia Duchala , Jill Giles-Komar , Jinquan Luo , Michael Rycyzyn , Raymond Sweet
IPC: A61K39/395 , G01N33/68 , C07K16/24 , A61K45/06 , A61K39/00
Abstract: An anti-IL-23 antibody, including isolated nucleic acids that encode at least one anti-IL-23 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.
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公开(公告)号：US10450377B2
公开(公告)日：2019-10-22
申请号：US15922136
申请日：2018-03-15
Applicant: Janssen Biotech, Inc.
Inventor： Karen Duffy , Natalie Fursov , LeRoy Hall , Catherine Healy , Roberta Lamb , Jinquan Luo , Ravi Malaviya , Michael Naso , Michael Pratta , Mark Tornetta , John Wheeler , Sheng-Jiun Wu
IPC: C07K16/28 , A61K39/395 , A61K38/01 , C07K16/44 , A61K39/00
Abstract: The present invention relates to ST2L antagonists, polynucleotides encoding the antagonists or fragments thereof, and methods of making and using the foregoing.
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公开(公告)号：US20190201527A1
公开(公告)日：2019-07-04
申请号：US16358775
申请日：2019-03-20
Applicant: Janssen Biotech, Inc.
Inventor： Jacqueline Benson , Mark Cunningham , Cynthia Duchala , Jill Giles-Komar , Jinquan Luo , Michael Rycyzyn , Raymond Sweet
IPC: A61K39/395 , C07K16/24 , A61K45/06 , G01N33/68
Abstract: An anti-IL-23 antibody, including isolated nucleic acids that encode at least one anti-IL-23 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.
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