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公开(公告)号：US5048959A
公开(公告)日：1991-09-17
申请号：US531871
申请日：1990-06-01
IPC分类号： G01J3/28
CPC分类号： G01J3/2846 , G01J3/2823
摘要： An imaging system for providing spectrographically resolved images. The system incorporates a one-dimensional spatial encoding mask which enables an image to be projected onto a two-dimensional image detector after spectral dispersion of the image. The dimension of the image which is lost due to spectral dispersion on the two-dimensional detector is recovered through employing a reverse transform based on presenting a multiplicity of different spatial encoding patterns to the image. The system is especially adapted for detecting Raman scattering of monochromatic light transmitted through or reflected from physical samples. Preferably, spatial encoding is achieved through the use of Hadamard mask which selectively transmits or blocks portions of the image from the sample being evaluated.
摘要翻译： 一种用于提供光谱分辨图像的成像系统。 该系统包含一维空间编码掩模，其能够使图像在图像的光谱色散之后投影到二维图像检测器上。 由于基于向图像呈现多个不同的空间编码图案，通过采用反向变换来恢复由于二维检测器上的频谱色散而丢失的图像的尺寸。 该系统特别适用于检测通过物理样品透射或反射的单色光的拉曼散射。 优选地，通过使用Hadamard掩模来实现空间编码，所述Hadamard掩模从被评估的样品中选择性地传输或阻挡图像的部分。
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52.发明申请TIME AND SPACE RESOLVED STANDOFF HYPERSPECTRAL IED EXPLOSIVES LIDAR DETECTOR 审中-公开时间和空间分辨率高分辨率高分辨率激光雷达探测器公开(公告)号：US20120120393A1
公开(公告)日：2012-05-17
申请号：US13290174
申请日：2011-11-07
CPC分类号： G01J3/36 , G01J3/02 , G01J3/0221 , G01J3/0264 , G01J3/2823 , G01J3/44 , G01N21/359 , G01N21/6456 , G01N21/65 , G01N21/718 , G01N2021/1738 , G01N2021/174 , G01N2021/1744
摘要： A system and method for standoff detection of explosives and explosive residue. A laser light source illuminates a target area having an unknown sample producing luminescence emitted photons, scattered photons and plasma emitted photons. A first optical system directs light to the target area. A video capture device outputs a dynamic image of the target area. A second optical system collects photons, and directs collected photons to a first two-dimensional array of detection elements and/or to a fiber array spectral translator device which device includes a two-dimensional array of optical fibers drawn into a one-dimensional fiber stack. A spectrograph is coupled to the one-dimensional fiber stack of the fiber array spectral translator device, wherein the entrance slit of the spectrograph is coupled to the one dimensional fiber stack.
摘要翻译： 爆炸物和爆炸物残留物检测的系统和方法。 激光源照射具有未知样品的目标区域，产生发光的光子，散射的光子和等离子体发射的光子。 第一光学系统将光引导到目标区域。 视频采集装置输出目标区域的动态图像。 第二光学系统收集光子，并将收集的光子引导到检测元件的第一二维阵列和/或光纤阵列光谱转换器装置，该装置包括被拉入一维光纤堆叠的光纤的二维阵列 。 光谱仪耦合到光纤阵列光谱转换器装置的一维光纤堆叠，其中光谱仪的入口狭缝耦合到一维光纤堆叠。
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公开(公告)号：US20120105838A1
公开(公告)日：2012-05-03
申请号：US13374703
申请日：2012-01-09
CPC分类号： G01N21/65 , G01N21/64 , G01N21/6402 , G01N21/8483 , G01N2021/6417
摘要： The invention relates to apparatus and methods for assessing occurrence of a hazardous agent in a sample by performing multipoint spectral analysis of the sample. Methods of employing Raman spectroscopy and other spectrophotometric methods are disclosed. Devices and systems suitable for performing such multipoint methods are also disclosed.
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54.发明申请Raman Chemical Imaging of Threat Agents Using Pulsed Laser Excitation and Time-Gated Detection 审中-公开使用脉冲激光激发和时间门控检测的威胁剂的拉曼化学成像公开(公告)号：US20100309464A1
公开(公告)日：2010-12-09
申请号：US12619336
申请日：2009-11-16
申请人： Patrick J. Treado , Matthew Nelson , Jeffrey Cohen , John Maier
发明人： Patrick J. Treado , Matthew Nelson , Jeffrey Cohen , John Maier
IPC分类号： G01J3/44
CPC分类号： G01J3/2803 , G01J3/0218 , G01J3/027 , G01J3/0291 , G01J3/2889 , G01J3/44 , G01N21/274 , G01N21/65 , G01N2201/0216 , G01N2201/0697
摘要： The disclosure provides for a system and method for detecting a threat agent. A sample is illuminated to produce photons Raman scattered and emitted by the sample. The Raman scattered photons are collected using time-gated detection without collecting the emitted photons. A Raman spectroscopic data set is generated from said Raman scattered photons wherein said Raman spectroscopic data comprises at least one of a Raman spectrum and a Raman chemical image. The Raman spectroscopic data is assessed to thereby determine the presence or absence of a threat agent in the sample. The sample may be in a target area. The sample may be illuminated using a pulsed laser or an intensity modulated laser. The illumination source may be synchronized with a gating element that enables time-gated detection.
摘要翻译： 本公开提供了用于检测威胁代理的系统和方法。 样品被照亮以产生被样品分散和发射的光子拉曼。 使用时间门控检测收集拉曼散射的光子，而不收集发射的光子。 从所述拉曼散射光子产生拉曼光谱数据集，其中所述拉曼光谱数据包括拉曼光谱和拉曼化学图像中的至少一个。 评估拉曼光谱数据，从而确定样品中威胁剂的存在或不存在。 样本可能在目标区域。 可以使用脉冲激光或强度调制激光来照亮样品。 照明源可以与启用时间门控检测的门控元件同步。
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公开(公告)号：US20100271629A1
公开(公告)日：2010-10-28
申请号：US11656393
申请日：2007-01-23
IPC分类号： G01J3/44
CPC分类号： G01J3/44 , G01J3/02 , G01J3/0218 , G01J3/0272 , G01J3/28 , G01J3/443 , G01N21/65 , G01N21/718 , G01N2201/0221
摘要： In one embodiment, the disclosure relates to a method for interrogating a sample by: illuminating a first region of the sample with a first illumination pattern to obtain a plurality of first sample photons; illuminating a second region of the sample with a second illumination pattern to obtain a plurality of second sample photons; processing the plurality of first sample photons to obtain a characteristic atomic emission of the first region and processing the plurality of second sample photons to obtain a Raman spectrum; and identifying the sample through at least one of the characteristic atomic emission of the first region or the Raman spectrum of the second region of the sample.
摘要翻译： 在一个实施例中，本公开涉及一种用于询问样本的方法，其中：用第一照明图案照射样品的第一区域以获得多个第一样品光子; 用第二照明图案照射样品的第二区域以获得多个第二样品光子; 处理多个第一样品光子以获得第一区域的特征原子发射并处理多个第二样品光子以获得拉曼光谱; 以及通过样品的第二区域的第一区域的特征性原子发射或拉曼光谱中的至少一个来识别样品。
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56.发明申请System and Method for Structured Illumination and Collection for Improved Optical Confocality of Raman Fiber Array Spectral Translator Imaging and Interactive Raman Probing 有权用于拉曼光纤阵列光谱转换成像和交互式拉曼探测的改进光学谐振的结构照明和采集系统和方法公开(公告)号：US20100148073A1
公开(公告)日：2010-06-17
申请号：US12632187
申请日：2009-12-07
CPC分类号： G01J3/2803 , G01J3/0221 , G01J3/44 , G01N21/474 , G01N21/55 , G01N21/645 , G01N21/6456 , G01N21/65 , G01N2021/6423 , G01N2021/6484 , G01N2201/0833 , G01N2201/0846 , G02B6/06
摘要： The disclosure relates generally to methods and apparatus for using telescope optics and a fiber array spectral translator-based (“FAST”) spectroscopic system for improved imaging, spectral analysis, and interactive probing of a sample. In an embodiment, the confocality of a fiber array spectral translator-based spectroscopic system is improved through the use of structured illumination and/or structured collection of photons. User input may be received and acted upon to allow a user to interactively in real time and/or near real time view and analyze specific regions of the sample.
摘要翻译： 本公开一般涉及用于使用望远镜光学器件的方法和装置以及用于改进样品的成像，光谱分析和交互式探测的光纤阵列光谱转换器（“FAST”）光谱系统。 在一个实施例中，通过使用结构化照明和/或光子的结构化收集来提高基于光纤阵列光谱转换器的光谱系统的共焦度。 可以接收用户输入并执行操作以允许用户以实时和/或接近实时的方式进行交互式查看和分析样本的特定区域。
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57.发明授权Time and space resolved standoff hyperspectral IED explosives LIDAR detection 有权时间和空间解决了高光谱IED爆炸物LIDAR检测公开(公告)号：US07692775B2
公开(公告)日：2010-04-06
申请号：US11450149
申请日：2006-06-09
IPC分类号： G01N21/00
CPC分类号： G01J3/36 , G01J3/02 , G01J3/0221 , G01J3/0264 , G01J3/2823 , G01J3/44 , G01N21/359 , G01N21/6456 , G01N21/65 , G01N21/718 , G01N2021/1738 , G01N2021/174 , G01N2021/1744
摘要： A system and method for standoff detection of explosives and explosive residue. A laser light source illuminates a target area having an unknown sample producing luminescence emitted photons, scattered photons and plasma emitted photons. A first optical system directs light to the target area. A video capture device outputs a dynamic image of the target area. A second optical system collects photons, and directs collected photons to a first two-dimensional array of detection elements and/or to a fiber array spectral translator device which device includes a two-dimensional array of optical fibers drawn into a one-dimensional fiber stack. A spectrograph is coupled to the one-dimensional fiber stack of the fiber array spectral translator device, wherein the entrance slit of the spectrograph is coupled to the one dimensional fiber stack.
摘要翻译： 爆炸物和爆炸物残留物检测的系统和方法。 激光源照射具有未知样品的目标区域，产生发光的光子，散射的光子和等离子体发射的光子。 第一光学系统将光引导到目标区域。 视频采集装置输出目标区域的动态图像。 第二光学系统收集光子，并将收集的光子引导到检测元件的第一二维阵列和/或光纤阵列光谱转换器装置，该装置包括被拉入一维光纤堆叠的光纤的二维阵列 。 光谱仪耦合到光纤阵列光谱转换器装置的一维光纤堆叠，其中光谱仪的入口狭缝耦合到一维光纤堆叠。
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公开(公告)号：US07551821B2
公开(公告)日：2009-06-23
申请号：US11744797
申请日：2007-05-04
CPC分类号： G02B6/06 , A61B1/00165 , A61B1/043 , A61B1/063 , A61B1/0638 , A61B1/0646 , A61B1/07 , A61B5/0075 , A61B5/0084 , G01J3/02 , G01J3/0208 , G01J3/0218 , G01J3/0227 , G01J3/024 , G01J3/0256 , G01J3/0262 , G01J3/0286 , G01J3/44 , G01J2003/1213
摘要： A fiberscope device is disclosed which is suitable for video imaging, laser Raman spectroscopy and laser Raman spectroscopic (i.e. chemical) imaging. The fiberscope design minimizes fiber background interference arising from the laser delivery fiber optic and the coherent fiber optic light gathering bundle while maintaining high light throughput efficiency through the use of integrated spectral filters. In the fiberscope design, the laser delivery fiber optic is offset from the coherent fiber optic light gathering bundle. The laser delivery field is captured entirely by the light gathering field of view of the coherent fiber bundle. The fiberscope incorporates spectral filter optical elements that provide environmental insensitivity, particularly to temperature and moisture. The fiberscope is suited to the analysis of a wide range of condensed phase materials (solids and liquids), including the analysis of biological materials such as breast tissue lesions and arterial plaques, in such a manner to delineate abnormal from normal tissues.
摘要翻译： 公开了适用于视频成像，激光拉曼光谱和激光拉曼光谱（即化学）成像的纤维内窥镜装置。 纤维镜设计可以最大限度地减少激光传输光纤和相干光纤采集光束产生的光纤背景干扰，同时通过使用集成光谱滤波器保持高光通量效率。 在纤维镜设计中，激光传输光纤与相干光纤聚光束偏移。 激光输送场完全由相干光纤束的聚光场捕获。 纤维镜包含光谱滤光器光学元件，其提供环境不敏感性，特别是对温度和湿度。 纤维内窥镜适用于分析各种凝聚相材料（固体和液体），包括分析生物材料如乳房组织损伤和动脉斑块，以便从正常组织中描绘异常。
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公开(公告)号：US20080084553A1
公开(公告)日：2008-04-10
申请号：US11632471
申请日：2005-07-14
CPC分类号： G01J3/44 , G01J3/28 , G01J3/2823 , G01N21/6486 , G01N21/65 , G01N2201/1293
摘要： In one embodiment, the disclosure relates to a method for detecting and classifying an unknown substance in a sample. The method including the steps of (a) providing a spectrum for each of a predetermined number of reference substances; (b) detecting an area of interest on said unknown substance; (c) targeting said area of interest; (d) determining a spectrum from said area of interest; (e) comparing the determined spectrum with the spectrum of one of the reference substances; and (f) classifying said unknown substance based on the comparison of spectra.
摘要翻译： 在一个实施方案中，本公开涉及用于检测和分类样品中未知物质的方法。 该方法包括以下步骤：（a）为预定数量的参考物质中的每一个提供光谱; （b）检测所述未知物质的感兴趣区域; （c）针对该地区的目标; （d）从所述感兴趣区域确定频谱; （e）将所确定的光谱与参考物质之一的光谱进行比较; 和（f）基于光谱的比较对所述未知物质进行分类。
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公开(公告)号：US07283241B2
公开(公告)日：2007-10-16
申请号：US11045080
申请日：2005-01-31
IPC分类号： G01N21/25
CPC分类号： G01N21/65 , G01J3/02 , G01J3/0291 , G01J3/36 , G01J3/44 , G01N21/359 , G01N21/59 , G01N21/6458 , G01N2021/6419 , G01N2021/6421 , G01N2021/656
摘要： The disclosure generally relates to a multimode imaging apparatus for simultaneously obtaining multiple wavelength-discriminative spectral images of a sample. In one embodiment, the apparatus includes an image selector having a rotator assembly, the rotator assembly housing a first plurality of optical components, the image selector adapted to receive a illuminating photons having a first wavelength and direct the illuminating photons to the sample, the image selector adapted to receive illuminating photons interacted with the sample and selectively direct said interacted photons to one of a plurality of detection sources; a microscope turret housing a second plurality of components, the microscope turret adapted to receive illuminating photons having a second wavelength and direct the photons to the sample; the microscopic turret adapted to receive illuminating photons interacted with the sample and selectively direct said interacted photons to one of a plurality of detection sources; wherein substantially all of the interacted photons are selectively directed one of a plurality of detection sources to form multiple wavelength discriminative spectral images of the sample simultaneously.
摘要翻译： 本公开总体上涉及用于同时获得样本的多个波长鉴别光谱图像的多模式成像装置。 在一个实施例中，该装置包括具有旋转器组件的图像选择器，旋转体组件容纳第一多个光学部件，图像选择器适于接收具有第一波长的照明光子并将照射光子引导到样本，图像 选择器，适于接收与样本相互作用的照明光子，并选择性地将所述相互作用的光子引导到多个检测源之一; 显微镜转台，其容纳第二多个部件，所述显微镜转台适于接收具有第二波长并且将所述光子引导到所述样品的照明光子; 适于接收与样品相互作用的照明光子并且选择性地将所述相互作用的光子引导到多个检测源中的一个的微观炮塔; 其中基本上所有相互作用的光子被选择性地指向多个检测源中的一个，以同时形成样品的多个波长鉴别光谱图像。
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