公开(公告)号：US08203716B2

公开(公告)日：2012-06-19

申请号：US12447992

申请日：2007-08-03

Applicant: Majid Badleirostami ,  Omid Momtahan ,  Chao Ray Hsieh ,  Ali Adibi

Inventor： Majid Badleirostami ,  Omid Momtahan ,  Chao Ray Hsieh ,  Ali Adibi

IPC: G01J3/45

CPC classification number: G03H1/0248 ,  G01J3/02 ,  G01J3/0205 ,  G01J3/2823 ,  G03H2001/0033

Abstract: Systems and methods for performing two-dimensional (2D) high resolution spectral-spatial mapping are described. At least one embodiment includes a spectrometer for performing two-dimensional (2D) high resolution spectral-spatial mapping comprising a Fabry-Perot component configured to receive a diffuse input beam and provide a high resolution spectral mapping of the diffuse input beam in a first direction. The spectrometer further comprises a volume hologram for increasing a spectral operating range, the volume hologram configured to perform spectral mapping in a second direction orthogonal to the first direction to increase the spectral operating range. The spectrometer further comprises a charged coupled device (CCD) configured to receive output beams, the output beams used to provide spectral analysis of the input beams.

Abstract translation: 描述了用于执行二维（2D）高分辨率光谱 - 空间映射的系统和方法。 至少一个实施例包括用于执行二维（2D）高分辨率光谱空间映射的光谱仪，其包括配置成接收漫射输入光束并且在第一方向上提供扩散输入光束的高分辨率光谱映射的法布里 - 珀罗分量 。 光谱仪还包括用于增加光谱操作范围的体积全息图，所述体积全息图被配置为在与第一方向正交的第二方向上执行光谱映射以增加光谱操作范围。 光谱仪还包括被配置为接收输出光束的电荷耦合器件（CCD），用于提供输入光束的光谱分析的输出光束。

公开(公告)号：US08179578B2

公开(公告)日：2012-05-15

申请号：US12374139

申请日：2006-07-18

Applicant: Joseph Rosen ,  Gary Brooker

Inventor： Joseph Rosen ,  Gary Brooker

IPC: G03H1/08 ,  G03H1/16 ,  G03H1/04

CPC classification number: G03H1/06 ,  G02B5/32 ,  G03H1/0005 ,  G03H1/0244 ,  G03H1/0443 ,  G03H1/08 ,  G03H5/00 ,  G03H2001/0033 ,  G03H2001/0066 ,  G03H2001/0447 ,  G03H2001/0458 ,  G03H2222/24 ,  G03H2223/12 ,  G03H2223/13 ,  G03H2225/33 ,  G03H2240/13 ,  G03H2240/24

Abstract: An apparatus and method to produce a hologram of an object includes an electromagnetic radiation assembly configured to receive a received electromagnetic radiation, such as light, from the object. The electromagnetic radiation assembly is further configured to diffract the received electromagnetic radiation and transmit a diffracted electromagnetic radiation. An image capture assembly is configured to capture an image of the diffracted electromagnetic radiation and produce the hologram of the object from the captured image.

Abstract translation: 用于产生物体的全息图的装置和方法包括：电磁辐射组件，被配置为从物体接收接收的电磁辐射，例如光。 电磁辐射组件还被配置为衍射接收的电磁辐射并传输衍射的电磁辐射。 图像捕获组件被配置为捕获衍射电磁辐射的图像并从捕获的图像产生对象的全息图。

公开(公告)号：US20110058172A1

公开(公告)日：2011-03-10

申请号：US12941568

申请日：2010-11-08

Applicant: JOHN A. MOON ,  ALAN D. KERSEY ,  MARTIN A. PUTNAM ,  TUO LI

Inventor： JOHN A. MOON ,  ALAN D. KERSEY ,  MARTIN A. PUTNAM ,  TUO LI

IPC: G01N21/25

CPC classification number: G01N33/552 ,  G01N21/4788 ,  G01N21/6428 ,  G01N21/645 ,  G01N21/6452 ,  G01N21/7743 ,  G01N33/54306 ,  G01N33/54313 ,  G01N33/54366 ,  G01N33/54386 ,  G03H1/0005 ,  G03H1/02 ,  G03H1/0236 ,  G03H1/26 ,  G03H2001/0033 ,  G03H2001/0044 ,  G03H2210/53 ,  G03H2210/63 ,  G03H2230/10 ,  G03H2250/12 ,  G06K19/04 ,  G06K19/06009

Abstract: A method of identifying analytes that react with probes on encoded particles. The method includes providing a support substrate that has a plurality of the particles randomly distributed on the support substrate. The particles have elongated bodies with codes that extend along the corresponding bodies. The codes identify probes that are attached to the corresponding bodies, wherein at least some of the probes include fluorescent labels from reactions with the analytes. The method also includes detecting fluorescent signals that are emitted from the fluorescent labels. The fluorescent signals emit from random spatial locations along the support substrate. The method also includes detecting the codes of the particles at the random spatial locations along the support substrate and analyzing the codes and the fluorescent signals to identify the analytes that react with the probes on the particles.

Abstract translation: 识别与编码粒子上的探针反应的分析物的方法。 该方法包括提供具有随机分布在支撑衬底上的多个颗粒的支撑衬底。 颗粒具有细长体，其具有沿相应体部延伸的代码。 代码识别附着于相应体的探针，其中至少一些探针包括与分析物反应的荧光标记。 该方法还包括检测从荧光标记物发射的荧光信号。 荧光信号沿着支撑衬底从随机空间位置发射。 该方法还包括沿着支撑衬底的随机空间位置检测颗粒的代码并分析代码和荧光信号以识别与颗粒上的探针反应的分析物。

公开(公告)号：US07839551B2

公开(公告)日：2010-11-23

申请号：US12020376

申请日：2008-01-25

Applicant: Sang-Hyuk Lee ,  David G. Grier

Inventor： Sang-Hyuk Lee ,  David G. Grier

IPC: G02B5/32

CPC classification number: G03H1/0005 ,  G01B9/021 ,  G02B21/0088 ,  G02B21/32 ,  G03H1/0443 ,  G03H1/0866 ,  G03H1/2294 ,  G03H2001/0033 ,  G03H2001/0077 ,  G03H2001/0447 ,  Y10S359/902

Abstract: A method and system for performing three-dimensional holographic microscopy of an optically trapped structure. The method and system use an inverted optical microscope, a laser source which generates a trapping laser beam wherein the laser beam is focused by an objective lens into a plurality of optical traps. The method and system also use a collimated laser at an imaging wavelength to illuminate the structure created by the optical traps. Imaging light scattered by the optically tapped structure forms holograms that are imaged by a video camera and analyzed by optical formalisms to determine light field to reconstruct 3-D images for analysis and evaluation.

Abstract translation: 用于执行光学捕获结构的三维全息显微镜的方法和系统。 该方法和系统使用倒置的光学显微镜，产生捕获激光束的激光源，其中激光束被物镜聚焦成多个光阱。 该方法和系统还使用成像波长处的准直激光来照亮由光阱产生的结构。 通过光学抽头结构散射的成像光形成由摄像机成像的全息图，并通过光学形式来分析以确定光场以重建用于分析和评估的3-D图像。

公开(公告)号：US07796271B2

公开(公告)日：2010-09-14

申请号：US11998395

申请日：2007-11-29

Applicant: Jürgen Reithinger

Inventor： Jürgen Reithinger

IPC: G01B9/021

CPC classification number: A61B5/1075 ,  A61B5/0059 ,  A61B5/1079 ,  A61B5/6817 ,  G03H1/0005 ,  G03H1/02 ,  G03H2001/0033 ,  G03H2001/0038 ,  G03H2001/0204 ,  G03H2210/30 ,  G03H2226/11 ,  G03H2227/02 ,  H04R25/70

Abstract: The aim is to be able to determine the spatial structure of an ear canal in a simple and reliable fashion. To this end, it is proposed to produce a hologram of the ear canal, by inserting a holography unit at least partially into the ear canal. The data for the shape of a housing shell or an otoplastic can then be obtained from the resulting hologram for automatic manufacturing methods.

Abstract translation: 目的是能够以简单可靠的方式确定耳道的空间结构。 为此，提出了通过将全息单元至少部分地插入到耳道中来产生耳道的全息图。 然后可以从所得到的全息图获得壳体或耳朵形状的数据，用于自动制造方法。

公开(公告)号：US20100208313A1

公开(公告)日：2010-08-19

申请号：US12372315

申请日：2009-02-17

Applicant: Adrian M. Horgan ,  Mark Giles ,  John D. Wiltshire

Inventor： Adrian M. Horgan ,  Mark Giles ,  John D. Wiltshire

IPC: B44F1/12 ,  G03H1/02 ,  G03H1/26

CPC classification number: G03H1/0011 ,  G03H1/0005 ,  G03H1/0248 ,  G03H1/0252 ,  G03H2001/0016 ,  G03H2001/0033 ,  G03H2001/0044 ,  G03H2001/186 ,  G03H2001/2615 ,  G03H2222/15 ,  G03H2223/20 ,  G03H2240/55 ,  G03H2250/37 ,  G03H2250/39 ,  G03H2260/16

Abstract: The nature of a volume hologram limits its use in security and sensing applications. Accordingly, a volume hologram segregated into a first and second region recording a first and second image, respectively, and wherein the second region is responsive to stimulus while the first region is protected physically from stimulus is provided. Also provided is a volume hologram with a functional cover disposed thereon to regulate how the volume hologram interacts with the stimulus when in the presence of stimulus. A volume hologram with a removable cover disposed thereon to permit a first recorded image to be viewed, to protect the volume hologram from physical damage, to prevent the volume hologram from interacting with the stimulus, and to be removed, thereby permitting the volume hologram to interact with the stimulus is provided as well. In these ways, the usability of volume holograms in security and sensing applications is increased.

Abstract translation: 体积全息图的性质限制了其在安全和感测应用中的应用。 因此，体积全息图分别分离成记录第一和第二图像的第一和第二区域，并且其中第二区域响应于刺激，而第一区域被物理地受刺激保护。 还提供了具有设置在其上的功能盖的体积全息图，以调节当存在刺激时体积全息图如何与刺激相互作用。 体积全息图，其上设置有可移除的盖，以允许观看第一记录图像，以保护体积全息图免受物理损伤，以防止体积全息图与刺激相互作用并被去除，从而允许体积全息图 还提供与刺激相互作用。 在这些方面，体积全息图在安全和感测应用中的可用性增加。

公开(公告)号：US07738150B2

公开(公告)日：2010-06-15

申请号：US11295626

申请日：2005-12-07

Applicant: Glen C. Larsen ,  Tyler Scott Gleghorn

Inventor： Glen C. Larsen ,  Tyler Scott Gleghorn

IPC: G03H1/00

CPC classification number: G03H1/00 ,  G03H1/0005 ,  G03H1/26 ,  G03H1/265 ,  G03H2001/0033 ,  G06K19/06018 ,  G06K2019/0629 ,  Y10S359/90

Abstract: Techniques for identifying encoded digital data in a multichannel hologram are described. A method can include steps of reading a first channel of a multichannel hologram, extracting first content data stored in the first channel, reading a second channel of the multichannel hologram, extracting second content data stored in the second channel, and utilizing the extracted content data. The extracted content data may be used for digital signature recognition. A system can include a multichannel hologram configured to store first, second, and third content data at first, second, and third channels respectively, at least one optical sensor configured to read the first, second, and third channels of the multichannel hologram and extract the first, second, and third content data, and a processor configured to measure an acceleration when the system is acted upon by a force.

Abstract translation: 描述用于识别多通道全息图中的编码数字数据的技术。 一种方法可以包括以下步骤：读取多通道全息图的第一通道，提取存储在第一通道中的第一内容数据，读取多通道全息图的第二通道，提取存储在第二通道中的第二内容数据，以及利用提取的内容数据 。 提取的内容数据可以用于数字签名识别。 系统可以包括多通道全息图，其被配置为分别在第一，第二和第三通道存储第一，第二和第三内容数据，至少一个光学传感器被配置为读取多声道全息图的第一，第二和第三声道并且提取 所述第一，第二和第三内容数据以及被配置为当所述系统被力作用时测量加速度的处理器。

公开(公告)号：US20100060962A1

公开(公告)日：2010-03-11

申请号：US12524725

申请日：2007-01-29

Applicant: Joseph Rosen

Inventor： Joseph Rosen

IPC: G03H1/16 ,  G03H1/00

CPC classification number: G03H1/26 ,  G03H1/0005 ,  G03H1/041 ,  G03H1/0443 ,  G03H1/06 ,  G03H1/08 ,  G03H5/00 ,  G03H2001/0033 ,  G03H2001/0452 ,  G03H2210/33 ,  G03H2223/23 ,  G03H2226/11

Abstract: An Apparatus and method to produce a hologram of a cross-section of an object includes an electromagnetic radiation assembly configured to receive a received electromagnetic radiation, such as light, from the object. The electromagnetic radiation assembly is further configured to diffract the received electromagnetic radiation and transmit a diffracted electromagnetic radiation An image capture assembly is configure to capture an image of the diffracted electromagnetic radiation and produce the hologram of the cross-section of the object from the captured image. The hologram of the cross-section includes information regarding a single cross-section of the object.

Abstract translation: 用于产生物体横截面的全息图的装置和方法包括被配置为从物体接收接收的电磁辐射（例如光）的电磁辐射组件。 电磁辐射组件还被配置为衍射接收的电磁辐射并传输衍射的电磁辐射。图像捕获组件被配置为捕获衍射的电磁辐射的图像，并从捕获的图像产生物体的横截面的全息图 。 横截面的全息图包括关于物体的单个横截面的信息。

公开(公告)号：US07659983B2

公开(公告)日：2010-02-09

申请号：US11607837

申请日：2006-11-30

Applicant: John A. Moon ,  Alan D. Kersey ,  Martin A. Putnam ,  Tuo Li

Inventor： John A. Moon ,  Alan D. Kersey ,  Martin A. Putnam ,  Tuo Li

IPC: G01N21/25

CPC classification number: G01N33/552 ,  G01N21/4788 ,  G01N21/6428 ,  G01N21/645 ,  G01N21/6452 ,  G01N21/7743 ,  G01N33/54306 ,  G01N33/54313 ,  G01N33/54366 ,  G01N33/54386 ,  G03H1/0005 ,  G03H1/02 ,  G03H1/0236 ,  G03H1/26 ,  G03H2001/0033 ,  G03H2001/0044 ,  G03H2210/53 ,  G03H2210/63 ,  G03H2230/10 ,  G03H2250/12 ,  G06K19/04 ,  G06K19/06009

Abstract: A method and apparatus for performing an assay process, featuring providing microbeads in a solution, each microbead having a particle substrate with a grating with a superposition of different predetermined regular periodic variations of the index of refraction disposed in the particle along a grating axis and indicative of a code; placing the microbeads on an alignment substrate; reading codes of the microbeads and the position thereof on the alignment substrate; reading the fluorescence on each microbead and the position order thereof on the alignment substrate; and determining an assay result based on bead position order and bead code of the earlier reading steps.

Abstract translation: 用于鉴定分析物的方法。 该方法包括提供多个微粒，其中每个微粒具有可光学检测的代码和与代码相关联的化学探针。 该方法还包括将微粒暴露于选择性结合至少一个微粒上的化学探针的靶分析物。 至少一个微粒上的光学可检测标记表明目标分析物已结合到化学探针上。 将微粒以随机方式提供到基底上。 该方法还包括确定基片上代码的代码和代码位置，并检测至少一个微粒上的标签和基片上标签的标签位置。 此外，该方法包括使用代码位置和标签位置来分析目标分析物。

公开(公告)号：US20090128825A1

公开(公告)日：2009-05-21

申请号：US12289589

申请日：2008-10-30

Applicant: Osman Akcakir

Inventor： Osman Akcakir

IPC: G01B9/021

CPC classification number: G01B9/021 ,  G01N21/453 ,  G01N21/6456 ,  G01Q20/02 ,  G01Q30/04 ,  G01Q60/20 ,  G03H1/0443 ,  G03H2001/0033 ,  G03H2001/0077 ,  G03H2001/045 ,  G03H2001/0458 ,  G03H2223/23

Abstract: The present invention utilizes a holographic optical forcing array for dynamic cellular probing and diagnostics. A holographic optical trapping system generates optical forces on objects so that deformations thereof may be quantified. In one embodiment, digital holography is used to generate an interference pattern, and an analysis thereof determines the phase profile which yields a measurement of the objects' shape deformation using only one image. In another embodiment, phase-stepped holography allows the phase profile of an object to be measured using only one image, by using a holographic optical element to make phase-shifted replicas of the beam in space. In another embodiment, the optical forcing array applies optical forces to beads placed on the objects' surface, deforming the objects. The beads' position is determined by applying Mie theory, and analysis thereof yields the three dimensional position of the beads, and a measurement of the deformation displacement on the objects' surface.

Abstract translation: 本发明利用全息光学强迫阵列进行动态细胞探测和诊断。 全息光学捕获系统在物体上产生光学力，从而可以量化其变形。 在一个实施例中，使用数字全息术来产生干涉图案，并且其分析确定相位轮廓，其仅使用一个图像来产生对象的形状变形的测量。 在另一个实施例中，相位阶全息术通过使用全息光学元件在空间中进行光束的相移复制，允许仅使用一个图像来测量物体的相位分布。 在另一个实施例中，光学强制阵列将光学力施加到放置在物体表面上的珠子上，使物体变形。 通过应用米氏理论确定珠的位置，分析其产生珠的三维位置，并测量物体表面上的变形位移。