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    Holographic Microscope and Data Processing Method for High-Resolution Hologram Image
    5.
    发明申请
    Holographic Microscope and Data Processing Method for High-Resolution Hologram Image 审中-公开
    全息显微镜和高分辨率全息图的数据处理方法

    公开(公告)号：US20160259297A1

    公开(公告)日：2016-09-08

    申请号：US15032434

    申请日：2014-10-28

    Applicant: UNIVERSITY OF HYOGO

    Inventor： Kunihiro SATO

    IPC: G03H1/04 ,  G02B21/36

    CPC classification number: G03H1/0443 ,  G02B21/00 ,  G02B21/06 ,  G02B21/365 ,  G03H2001/005 ,  G03H2001/0445 ,  G03H2001/0447 ,  G03H2001/045 ,  G03H2001/0452 ,  G03H2001/046 ,  G03H2001/0463 ,  G03H2001/0469 ,  G03H2001/0471 ,  G03H2222/42 ,  G03H2222/44 ,  G03H2222/52 ,  G03H2240/56

    Abstract: The present invention can realize both a transmission type and a reflection type, and provides a holographic microscope which can exceed the resolution of the conventional optical microscope, a hologram data acquisition method for a high-resolution image, and a high-resolution hologram image reconstruction method. In-line spherical wave reference light (L) is recorded in a hologram (ILR) using spherical wave reference light (R), and an object light (Oj) and an illumination light (Qj) are recorded in a hologram (IjOQR) using a spherical wave reference light (R) by illuminating the object with an illumination light (Qj, j=1, . . . , N) which is changed its incident direction. From those holograms, a hologram (JjOQL), from which the component of the reference light (R) is removed, is generated, and from the hologram, a light wave (hj) is generated. A light wave (cj) of the illumination light (Qj) is separated from the light wave (hj), and using its phase component (ξj=cj/|cj|), a phase adjustment reconstruction light wave is derived and added up as (HP=Σhj/ξj), and an object image (SP=|HP|2) is reconstructed.

    Abstract translation: 本发明可以实现透射型和反射型，并且提供可以超过常规光学显微镜的分辨率的全息显微镜，用于高分辨率图像的全息图数据获取方法和高分辨率全息图像重构 方法。 使用球面波参考光（R）将球面波参考光（L）记录在全息图（ILR）中，并且将目标光（Oj）和照明光（Qj）记录在全息图（IjOQR）中，使用 通过以改变其入射方向的照明光（Qj，j = 1，...，N）照亮物体的球面波参考光（R）。 从这些全息图中，产生去除了参考光（R）的分量的全息图（JjOQL），并且从全息图产生光波（hj）。 照明光（Qj）的光波（cj）与光波（hj）分离，使用其相位分量（ξj= cj / | cj |），导出相位调整重建光波，并相加为 （HP =Σhj/ξj），并且重建对象图像（SP = | HP | 2）。

    Phase image acquisition device
    7.
    发明授权
    Phase image acquisition device 有权
    相位图像采集装置

    公开(公告)号：US09134109B2

    公开(公告)日：2015-09-15

    申请号：US13695330

    申请日：2011-05-02

    Applicant: Hidenao Iwai ,  Masatoshi Fujimoto

    Inventor： Hidenao Iwai ,  Masatoshi Fujimoto

    IPC: G01B9/02 ,  G01N21/41 ,  G02B21/14 ,  G02B27/52 ,  G03H1/04 ,  G03H1/08

    CPC classification number: G01B9/02045 ,  G01N21/41 ,  G02B21/14 ,  G02B27/52 ,  G03H1/0443 ,  G03H1/0866 ,  G03H2001/0447 ,  G03H2001/045 ,  G03H2001/0463 ,  G03H2210/62

    Abstract: Provided is an observation device which can obtain a phase image of a moving object rapidly with high sensitivity even when using a photodetector having a slow read-out speed per pixel. The observation device 1 comprises a light source 10, a first modulator 20, a second modulator 30, a lens 40, a beam splitter 41, a photodetector 46, and an arithmetic unit 50. The lens 40 receives scattered light generated by a moving object 2 and forms a Fourier transform image of the object 2. The photodetector 46 outputs data representing a sum in a v direction of data temporally changing at a frequency corresponding to a Doppler shift frequency of the light having reached each position on a light-receiving surface through the lens 40 at each position in a u direction at each time. The arithmetic unit 50 obtains an image of the object 2 according to the output of the photodetector 46.

    Abstract translation: 提供一种观察装置，即使使用每像素读出速度慢的光检测器，也能够以高灵敏度快速获得移动体的相位图像。 观察装置1包括光源10，第一调制器20，第二调制器30，透镜40，分束器41，光电检测器46和运算单元50.透镜40接收由移动物体产生的散射光 形成物体2的傅立叶变换图像。光电检测器46输出表示在光接收表面上到达每个位置的光的多普勒频移对应的频率的时间上变化的数据的AV方向上的数据的数据通过 每次在au方向的每个位置处的透镜40。 算术单元50根据光检测器46的输出获得对象2的图像。

    METHOD AND APPARATUS FOR MOTILITY CONTRAST IMAGING
    8.
    发明申请
    METHOD AND APPARATUS FOR MOTILITY CONTRAST IMAGING 审中-公开
    用于动态对比成像的方法和装置

    公开(公告)号：US20150062592A1

    公开(公告)日：2015-03-05

    申请号：US14537496

    申请日：2014-11-10

    Applicant: Purdue Research Foundation

    Inventor： David D. Nolte ,  John J. Turek ,  Kwan Jeong

    IPC: G01B9/02 ,  H01L27/146

    CPC classification number: G01B9/02091 ,  G01B9/02032 ,  G01B9/02082 ,  G03H1/0443 ,  G03H1/08 ,  G03H2001/0445 ,  G03H2001/045 ,  G03H2001/0467 ,  G03H2210/62 ,  G03H2222/33 ,  G03H2223/20 ,  H01L27/146

    Abstract: A system for motility contrast imaging a biological target within tissue comprising a CCD array; an illumination source for generating an incoming beam; a first beam splitter for receiving the incoming beam and producing an object beam and a reference beam; a second beam splitter for illuminating a multitude of biological targets with the object beam and for directing backscattered object beams towards the CCD array; a computer-controlled delay stage for zero-path-matching the reference beam to the backscattered object beams; a reference beam that intersects the backscattered object beams at an angle to produce a series of interference fringes that modulate Fourier-domain information; and a computer for receiving a time series of Fourier-domain information. The interference fringes between the backscattered object beam and the reference beam are recorded by the CCD array and passed to the computer which constructs a digital hologram at successive times.

    Abstract translation: 一种用于对包含CCD阵列的组织内的生物靶进行运动对比成像的系统; 用于产生进入光束的照明源; 用于接收入射光束并产生物体光束和参考光束的第一分束器; 第二分束器，用于用物体光束照射多个生物靶，并用于将反向散射的物体光束引向CCD阵列; 计算机控制的延迟级，用于将参考光束与背散射物体光束零路径匹配; 参考光束以一角度与后向散射物体光束相交，以产生一系列调制傅立叶域信息的干涉条纹; 以及用于接收傅立叶域信息的时间序列的计算机。 后向散射物体光束和参考光束之间的干涉条纹由CCD阵列记录并传递到连续构建数字全息图的计算机。

    COMPLETE DIGITAL HOLOGRAPHIC IMAGE SENSOR-PROJECTOR COMPUTING UNIT
    9.
    发明申请
    COMPLETE DIGITAL HOLOGRAPHIC IMAGE SENSOR-PROJECTOR COMPUTING UNIT 有权
    完整的数字全息图像传感器 - 投影仪计算单元

    公开(公告)号：US20120274568A1

    公开(公告)日：2012-11-01

    申请号：US13161903

    申请日：2011-06-16

    Applicant: Victor Lenchenkov ,  Dongqing Cao

    Inventor： Victor Lenchenkov ,  Dongqing Cao

    IPC: G06F3/01 ,  G03H1/26 ,  G03H1/16

    CPC classification number: G03H1/0443 ,  G03H1/0005 ,  G03H1/2294 ,  G03H2001/0088 ,  G03H2001/045 ,  G03H2001/0825

    Abstract: A hologram projecting system includes a coherent light source for emitting a reference beam onto a real object; and an image sensor for receiving the reference beam and a scattered beam reflected from the real object, and recording a Fourier image of the real object. Also included is a modulator for receiving the Fourier image. The reference beam is passed through the modulator, and configured to interact with the Fourier image to form a virtual image of the real object. The image sensor includes an n×m pixel array, where n and m are numbers of rows and columns, respectively. The modulator includes an n×m pixel array corresponding to the n×m pixel array of the image sensor. The pixels in the n×m pixel array of the image sensor control transmissivity of light in corresponding pixels of the n×m pixel array of the modulator.

    Abstract translation: 全息投影系统包括用于将参考光束发射到真实物体上的相干光源; 以及用于接收参考光束的图像传感器和从真实物体反射的散射光束，并且记录真实物体的付里叶图像。 还包括用于接收傅里叶图像的调制器。 参考光束通过调制器，并被配置为与傅立叶图像交互以形成真实对象的虚拟图像。 图像传感器包括n×m像素阵列，其中n和m分别是行和列的数量。 调制器包括对应于图像传感器的n×m像素阵列的n×m像素阵列。 图像传感器的n×m像素阵列中的像素控制调制器的n×m像素阵列的相应像素中的光的透射率。

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