摘要:
A system and method for converting organic wastes to biodegradable thermoplastic materials including polyhydroxyalkanoates is disclosed, which method includes treating the organic wastes with an acidogenic microbial population to form fermentative organic acids, and polymerization of the organic acids by PHA-producing microbial species to form PHAs. The system includes a first compartment for acidogenesis of organic wastes without oxygen, and a second compartment, for polymer synthesis by enriched cultures of species with oxygen such as R. eutropha, P. oleovorans, or mixtures thereof. The compartments are integrated with barriers that permit mass transfer of organic acids while maintaining different culture conditions in the compartments.
摘要:
A painted steel article having a steel surface, being plated with a corrosion-resistant coating. The corrosion-resistant coating contains at least 90% zinc, cobalt, at least one trivalent or higher-valent metal, and at least one colloidal inorganic material. The paint is then electrodeposited directly on the corrosion-resistant coating.
摘要:
The invention discloses binding agents to the E746-A750 deletion and the L858R point mutations in the epidermal growth factor receptor (EGFR) molecule, and methods for use thereof, including methods for the diagnosis and treatment of cancer.
摘要:
A memory device, and a method of forming a memory device, is provided that includes a capacitor with a lower electrode of a metal semiconductor alloy. In one embodiment, the memory device includes a trench present in a semiconductor substrate including a semiconductor on insulating (SOI) layer on top of a buried dielectric layer, wherein the buried dielectric layer is on top of a base semiconductor layer. A capacitor is present in the trench, wherein the capacitor includes a lower electrode of a metal semiconductor alloy having an upper edge that is self-aligned to the upper surface of the base semiconductor layer, a high-k dielectric node layer, and an upper electrode of a metal. The memory device further includes a pass transistor in electrical communication with the capacitor.
摘要:
An electrical fuse has an anode contact on a surface of a semiconductor substrate. The electrical fuse has a cathode contact on the surface of the semiconductor substrate spaced from the anode contact. The electrical fuse has a link within the substrate electrically interconnecting the anode contact and the cathode contact. The link comprises a semiconductor layer and a silicide layer. The silicide layer extends beyond the anode contact. An opposite end of the silicide layer extends beyond the cathode contact. A silicon germanium region is embedded in the semiconductor layer under the silicide layer, between the anode contact and the cathode contact.
摘要:
Methods and apparatus for supporting targeted advertising and/or other targeted applications in set top boxes which use data and/or applications, e.g., EBIF (Enhanced TV Binary Interchange Format) applications, are described. Application level targeting is supported in which an application running on different STBs presents different application behavior and/or presents different visual sub-elements depending on the content of a subscriber profile on the particular individual STB. In the case of addressability at the Application Layer an EBIF application can target different viewers by checking private User Preference Items at runtime. Addressability at the signaling/platform level is also supported allowing targeting of a specific application or a sub-element within an application to a specific target group. In this scenario the particular applications/sub-elements are loaded on the set-tops that belong to a target group, e.g., satisfy targeting constraints specified in private targeting metadata that is received in an MPEG stream.
摘要:
Novel gene deletions and translocations involving chromosome 2 resulting in fusion proteins combining part of Anaplastic Lymphoma Kinase (ALK) kinase with part of a secondary protein have been identified herein in human solid tumors, e.g. non-small cell lung carcinoma (NSCLC). Secondary proteins include Echinoderm Microtubule-Associated Protein-Like 4 (EML-4) and TRK-Fusion Gene (TFG). The EML4-ALK fusion protein, which retains ALK tyrosine kinase activity, was confirmed to drive the proliferation and survival of NSCLC characterized by this mutation. The invention therefore provides, in part, isolated polynucleotides and vectors encoding the disclosed mutant ALK kinase polypeptides, probes for detecting it, isolated mutant polypeptides, recombinant polypeptides, and reagents for detecting the fusion and truncated polypeptides. The disclosed identification of this new fusion protein enables methods for screening for compounds that inhibit the proteins, and methods for inhibiting the progression of a cancer characterized by the mutant polynucleotides or polypeptides.
摘要:
The invention discloses binding agents to the E746-A750 deletion and the L858R point mutations in the epidermal growth factor receptor (EGFR) molecule, and methods for use thereof, including methods for the diagnosis and treatment of cancer.