摘要:
The present invention relates to substantially pure FXR1 and FXR2 proteins and isolated nucleic acid molecules encoding the same. Recombinant expression vectors comprising nucleic acid sequences that encode FXR1 and FXR2 protein are also provided. Antibodies which bind to an epitope of FXR1 or FXR2, or FMR1 protein are also provided. The present invention also relates to methods of screening individuals for FMR1 deficiency using antibodies or nucleic acid molecules of the invention and pharmaceutical kits for accomplishing the same.
摘要:
Electroluminescent phosphors having substantially increased luminance and maintenance over that of prior art electroluminescent phosphors may be made by (1) doping an inorganic intercalation compound having an atomic structure interspersed with vacant spaces, with selected activator ions capable of luminescent emission, and (2) introducing organic monomers or other conductive material into the vacant spaces of the atomic structure of the doped inorganic intercalation compound. The organic monomers may be polymerized in situ to form conductive polymers therein.
摘要:
Electroluminescent phosphors having substantially increased luminance and maintenance over that of prior art electroluminescent phosphors may be made by (1) doping an inorganic intercalation compound having an atomic structure interspersed with vacant spaces, with selected activator ions capable of luminescent emission, and (2) introducing organic monomers or other conductive material into the vacant spaces of the atomic structure of the doped inorganic intercalation compound. The organic monomers may be polymerized in situ to form conductive polymers therein.
摘要:
The present invention relates to a pyridonaphthyridine compound as represented by general formula (I), which has a dual PI3K and mTOR inhibition effect, and its pharmaceutically acceptable salt, stereoisomer and deuteride thereof, wherein R1, R2, R3, R4, R5, R6, R7 and X are as defined in the specification; the present invention also relates to a method for preparing said compound, a pharmaceutical composition and a pharmaceutical formulation containing said compound, and uses of said compound in treating and/or preventing a proliferative disease and in the manufacture of a medicament for treating and/or preventing a proliferative disease.
摘要:
Methods and compositions are presented for use in diagnostic, imaging or targeting of therapeutic agents to treat obesity/adiposity-associated disorders, where such as compositions and methods identify and use peptides to selectively target adipose tissue stromal cells in mammals, both in vitro and in vivo.
摘要:
A self-charging power pack (300) includes a cathode (312) and an anode (310) that is spaced apart from the cathode (312). An electrolyte (318) is disposed between the anode (310) and the cathode (312). A piezoelectric ion transport layer (322) is disposed between the anode (310) and the cathode (312). The piezoelectric ion transport layer (322) has a piezoelectric property that generates a piezoelectric field when a mechanical force is applied thereto. The piezoelectric field causes transportation of ions in the electrolyte (318) through the piezoelectric ion transport layer (322) towards the anode (310).
摘要:
A method includes receiving in a communication terminal a sequence of downlink frames from a communication network that includes multiple cells arranged in first and second layers. The first layer corresponds to a first class of cells selected from a group of classes consisting of macro-cells, micro-cells, pico-cells, femto-cells and low-power nodes (LPN). The second layer corresponds to a second class of cells, different from the first class. One or more cross-layer frames in which at least a first cell in the first layer and at least a second cell in the second layer transmit data, and one or more same-layer frames in which only one or more of the cells in a single layer that currently serves the terminal transmit the data, are identified in the sequence. Cross-layer channel feedback is calculated over the cross-layer frames, and same-layer channel feedback is calculated over the same-layer frames.
摘要:
Methods and compositions are presented for use in diagnostic, imaging or targeting of therapeutic agents to treat obesity/adiposity-associated disorders, where such as compositions and methods identify and use peptides to selectively target adipose tissue stromal cells in mammals, both in vitro and in vivo.
摘要:
A method includes receiving a Multiple-Input Multiple Output (MIMO) signal over multiple communication channels from an antenna array including a first set of antennas having a first polarization and a second set of the antennas having a second polarization that is orthogonal to the first polarization. First feedback information is calculated relating to first interrelations between the antennas within either the first set or the second set. Second feedback information is calculated relating at least to second interrelations between the first set and the second set of the antennas. The first feedback information is transmitted at a first time/frequency granularity, and the second feedback information is transmitted at a second time/frequency granularity that is finer than the first time/frequency granularity.