公开(公告)号：US08900295B2

公开(公告)日：2014-12-02

申请号：US13626732

申请日：2012-09-25

Applicant: Edwards Lifesciences Corporation

Inventor： John F. Migliazza ,  Hugues LaFrance ,  Harvey H. Chen ,  Travis Zenyo Oba

IPC: A61F2/24 ,  A61B17/04 ,  A61B17/06

CPC classification number: A61F2/2412 ,  A61B17/0401 ,  A61B17/0487 ,  A61B2017/0417 ,  A61B2017/0437 ,  A61B2017/0441 ,  A61B2017/0464 ,  A61B2017/0496 ,  A61B2017/06176 ,  A61F2/2409 ,  A61F2/2418 ,  A61F2/2457 ,  A61F2250/0007

Abstract: A prosthetic valve assembly and method of implanting same is disclosed. The prosthetic valve assembly includes a prosthetic valve formed by support frame and valve leaflets, with one or more tethers each having a first end secured to the support frame and the second end attached to, or configured for attachment to, to papillary muscles or other ventricular tissue. The tether is configured and positioned so as to avoid contact or other interference with movement of the valve leaflets, while at the same time providing a tethering action between the support frame and the ventricular tissue. The valve leaflets may be flexible (e.g., so-called tissue or synthetic leaflets) or mechanical.

Abstract translation: 公开了一种人造瓣膜组件及其植入方法。 假体瓣膜组件包括由支撑框架和瓣膜小叶形成的假体瓣，其中一个或多个系绳各自具有固定到支撑框架的第一端和附接到乳突肌或其它心室的第二端 组织。 系绳的构造和定位是为了避免接触或其他干扰瓣叶片的移动，同时在支撑框架和心室组织之间提供束缚作用。 瓣膜小叶可以是柔性的（例如，所谓的组织或合成小叶）或机械的。

公开(公告)号：US20130053949A1

公开(公告)日：2013-02-28

申请号：US13660780

申请日：2012-10-25

Applicant: Edwards Lifesciences Corporation

Inventor： Rafael Pintor ,  Mark Chau ,  Travis Zenyo Oba ,  August R. Yambao ,  Louis A. Campbell ,  Tammy Huntley ,  Quinggang Zeng ,  Carey L. Cristea ,  Faisal Kalam

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2/2409 ,  A61F2/243 ,  A61F2/2433 ,  A61F2220/0016 ,  A61F2220/0025 ,  A61F2220/005 ,  A61F2220/0075 ,  A61F2220/0083 ,  A61F2230/0054 ,  A61F2230/0067 ,  A61F2230/0069 ,  A61F2230/0078 ,  A61F2250/006

Abstract: A heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The prosthetic valve has a base stent that is deployed at a treatment site, and a valve component configured to quickly connect to the base stent. The base stent may take the form of a self- or balloon-expandable stent that expands outward against the native valve with or without leaflet excision. The valve component has a non-expandable prosthetic valve and a self- or balloon-expandable coupling stent for attachment to the base stent, thereby fixing the position of the valve component relative to the base stent. The prosthetic valve may be a commercially available valve with a sewing ring and the coupling stent attaches to the sewing ring. The system is particularly suited for rapid deployment of heart valves in a conventional open-heart surgical environment.

Abstract translation: 提供了可以在手术过程中快速且容易地植入的心脏瓣膜假体。 假体瓣膜具有部署在治疗部位的基部支架和构造成快速连接到基部支架的阀部件。 基底支架可以采取自体或球囊扩张的支架的形式，其在具有或不具有小叶切除的情况下相对于天然瓣膜向外扩张。 阀部件具有不可扩张的假体瓣膜和用于附接到基底支架的自支撑或球囊扩张的联接支架，由此固定阀部件相对于基底支架的位置。 假体阀可以是具有缝合环的市售阀，并且联接支架附接到缝合环。 该系统特别适用于在常规开心手术环境中快速部署心脏瓣膜。

公开(公告)号：US20240173122A1

公开(公告)日：2024-05-30

申请号：US18427999

申请日：2024-01-31

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Mark Chau ,  Marlowe E. Patterson ,  Seung-Beom Yi ,  Stephen C. Geist ,  Travis Zenyo Oba

IPC: A61F2/24

CPC classification number: A61F2/2412 ,  A61F2/2409 ,  A61F2/2418 ,  A61F2/2427 ,  A61F2/2445 ,  A61F2/246 ,  A61F2210/0014 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2230/0069 ,  A61F2250/006 ,  A61F2250/0063

Abstract: A prosthetic spacer assembly includes a spacer body, a first anchor, and a second anchor. The first anchor and the second anchor each extend from the spacer body. The spacer body is radially compressible and self-expandable. The spacer body is configured for placement between the anterior and posterior native valve leaflets.

公开(公告)号：US20240081988A1

公开(公告)日：2024-03-14

申请号：US18511999

申请日：2023-11-16

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Shrojalkumar M. Desai ,  Travis Zenyo Oba ,  Sam Shafigh ,  Mark Chau ,  Jean-Pierre Michel Rabbah ,  Paul Kaye ,  Rupesh Gajanan Nawalakhe ,  Radhika Vaid ,  Sandip Vasant Pawar ,  Gillian Irene Armstrong ,  Ekaterina Tkatchouk

IPC: A61F2/24 ,  A61L17/10 ,  A61L27/18 ,  C08L75/04 ,  D01F1/10 ,  D01F6/90 ,  D01F6/92 ,  D01F6/94 ,  D02G1/16 ,  D02G3/32 ,  D02G3/36 ,  D02G3/44 ,  D03D1/00 ,  D03D15/283 ,  D04B1/16 ,  D04B1/18 ,  D04B21/16 ,  D04B21/18 ,  D04H1/4326 ,  D04H1/56 ,  D04H1/728

CPC classification number: A61F2/2418 ,  A61L17/10 ,  A61L27/18 ,  C08L75/04 ,  D01F1/10 ,  D01F6/90 ,  D01F6/92 ,  D01F6/94 ,  D02G1/16 ,  D02G3/32 ,  D02G3/36 ,  D02G3/448 ,  D03D1/00 ,  D03D15/283 ,  D04B1/16 ,  D04B1/18 ,  D04B21/16 ,  D04B21/18 ,  D04H1/4326 ,  D04H1/56 ,  D04H1/728 ,  A61F2002/075 ,  C08L2201/06 ,  D10B2331/00 ,  D10B2331/02 ,  D10B2331/04 ,  D10B2331/10 ,  D10B2509/04

Abstract: An implant includes a frame, and a textile mounted on the frame. The textile includes fibers formed from a mixture of a polymer and an additive molecule. The additive molecule includes a polyurethane backbone and one or more fluorinated end-groups at at least one end of the backbone. Other embodiments are also described.

公开(公告)号：US20230338145A1

公开(公告)日：2023-10-26

申请号：US18339497

申请日：2023-06-22

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Eric Michael Oberwise ,  Grant Matthew Stearns ,  Lauren R. Freschauf ,  Michael J. Popp ,  Steven M. Ford ,  Rachel Liat David Foreman ,  Rachel Ann Gohres ,  Chris J. Okos ,  Eric Robert Dixon ,  Asher L. Metchik ,  Michael D. Franklin ,  Travis Zenyo Oba ,  Daniel James Montoya ,  Mindy Lee Ann Black ,  Aviv Galon ,  Munir Hicham Eltal ,  Eran Hoffer

IPC: A61F2/24

CPC classification number: A61F2/246 ,  A61F2/2466 ,  A61F2/2445 ,  A61F2/2463 ,  A61F2220/0016 ,  A61F2210/0014

Abstract: An implantable device or implant is configured to be positioned within a native heart valve to allow the native heart valve to form a more effective seal. In some implementations, the implantable device or implant, or one or more portions thereof, can be configured to expand and/or contract. For example, the implantable device or implant can narrow during delivery and expand on implantation on the native heart valve.

公开(公告)号：US20230157814A1

公开(公告)日：2023-05-25

申请号：US18099209

申请日：2023-01-19

Applicant: Edwards Lifesciences Corporation

Inventor： Travis Zenyo Oba ,  Matthew A. Peterson ,  Glen T. Rabito ,  Alexander H. Cooper ,  David Robert Landon ,  J. Brent Ratz ,  Seung-Beom Yi

IPC: A61F2/24 ,  A61L27/36 ,  A61L27/04

CPC classification number: A61F2/2409 ,  A61F2/2418 ,  A61L27/04 ,  A61L27/3625 ,  A61F2/2412 ,  A61F2/2436 ,  A61F2220/0008 ,  A61F2220/0075 ,  A61F2230/0093 ,  A61F2250/0018 ,  A61F2250/0039 ,  A61F2250/0063 ,  A61L2430/20

Abstract: A replacement mitral valve prosthesis includes a support structure and a valve body having three flexible leaflets. The support structure preferably includes an internal valve frame and an external sealing frame. The valve frame supports the flexible leaflets. The sealing frame is adapted to conform to the shape of the native mitral valve annulus. The sealing frame may be coupled to an inlet end of the valve frame, an outlet end of the valve frame, or both. A plurality of anchors is coupled to the outlet end of the valve frame. The anchors extend radially outwardly for placement behind native leaflets. The prosthesis preferably includes a skirt disposed along an exterior of the external sealing frame. The prosthesis is collapsible for delivery into the heart via a delivery catheter. The prosthesis is configured to self-expand for deployment in the heart when released from the delivery catheter.

公开(公告)号：US11638644B2

公开(公告)日：2023-05-02

申请号：US17175004

申请日：2021-02-12

Applicant: Edwards Lifesciences Corporation

Inventor： Robert C. Taft ,  Travis Zenyo Oba

IPC: B23Q3/00 ,  A61F2/24 ,  A61F2/95 ,  A61F2/958

Abstract: A crimping system for a prosthetic heart valve comprises a split funnel comprising an elongated annular body having an enlarged insertion end, a narrower outlet end, and a central opening extending along a central longitudinal axis of the split funnel, between the insertion end and the outlet end. The body comprises first and second slots extending axially along opposite sides of the body from the outlet end toward the insertion end, the first and second slots defining first and second split portions of the body extending circumferentially between the first and second slots on opposite sides of the central opening. The crimping device is configured to crimp a prosthetic heart valve moving axially through the central opening from the insertion end to the outlet end while allowing portions of the prosthetic heart valve to protrude through the first and second slots and remain in an expanded configuration.

公开(公告)号：US11413147B2

公开(公告)日：2022-08-16

申请号：US16549133

申请日：2019-08-23

Applicant: Edwards Lifesciences Corporation

Inventor： Travis Zenyo Oba

IPC: A61F2/24 ,  A61B17/04

Abstract: A method for treating a heart valve involves introducing a delivery catheter into a target ventricle of a heart, the delivery catheter having a coil device disposed at least partially therein, deploying a distal end of the coil device from the delivery catheter, navigating the distal end of the coil device behind a plurality of trabeculae carneae features associated with an inner wall of the ventricle to form one or more coils, and tightening the one or more coils to reduce a diameter of the target ventricle.

公开(公告)号：US11311378B2

公开(公告)日：2022-04-26

申请号：US16908375

申请日：2020-06-22

Applicant: Edwards Lifesciences Corporation

Inventor： Frederic B. Hodshon ,  Rafael Pintor ,  August R. Yambao ,  Abhishek Gautam ,  Louis A. Campbell ,  Lawrence J. Farhat ,  Tammy Huntley ,  Faisal Kalam ,  Travis Zenyo Oba ,  Qinggang Zeng

IPC: A61F2/24 ,  A61F2/00

Abstract: Packaging for prosthetic heart valves including an assembly for securely retaining a heart valve within a jar and facilitating retrieval therefrom. The assembly includes a packaging sleeve that fits closely within the jar and has a clip structure for securing a valve holder. Contrary to previous designs, in one embodiment the valve holder is directed downward into the jar, and the valve is retained with an inflow end upward. The valve may have flexible leaflets, and a leaflet parting member on the end of the shaft extends through the leaflets and couples with the valve holder. The assembly of the packaging sleeve, valve, and holder can then be removed from the jar and a valve delivery tube connected with the holder, or to the leaflet parting member. The packaging sleeve may be bifurcated into two halves connected at a living hinge to facilitate removal from around the valve/holder subassembly.

公开(公告)号：US20220104940A1

公开(公告)日：2022-04-07

申请号：US17553566

申请日：2021-12-16

Applicant: Edwards Lifesciences Corporation

Inventor： Matthew A. Peterson ,  Seung-Beom Yi ,  Siddharth Vad ,  Travis Zenyo Oba ,  Lauren R. Freschauf ,  Amanda French ,  Yaron Keidar ,  Yuanlong Du ,  Gregory Bak-Boychuk ,  Kevin M. Golemo ,  Alexander H. Cooper

IPC: A61F2/24

Abstract: A prosthesis can be configured to grasp intralumenal tissue when deployed within a body cavity and prevent axial flow of fluid around an exterior of the prosthesis. The prosthesis can include an expandable frame configured to radially expand and contract for deployment within the body cavity and a valve body. The expandable frame can include a frame body and a supplemental frame. The valve body can include a plurality of leaflets and one or more intermediate components. The one or more intermediate components can couple at least a portion of the leaflets to the expandable frame. The prosthesis can include an annular flap positioned around an exterior of the expandable frame.