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132 条记录 (耗时 0.05 秒)

    Projecting images onto a surface
    65.
    发明授权
    Projecting images onto a surface 有权

    公开(公告)号：US07006707B2

    公开(公告)日：2006-02-28

    申请号：US09848017

    申请日：2001-05-03

    申请人： John Peterson

    发明人： John Peterson

    IPC分类号： G06T3/00

    CPC分类号： G06T3/005 ,  G06T3/0081

    摘要： The orientation of a camera associated with a first image is determined based on a shape of a perimeter of a corrected version of the first image. The corrected version of the first image has less perspective distortion relative to a reference image than the first image. The shape of the perimeter of the corrected version of the first image is also different from the shape of the perimeter of the first image. The first image is then projected onto a surface based on the orientation of the camera.

    High affinity small molecule C5a receptor modulators
    67.
    发明授权
    High affinity small molecule C5a receptor modulators 失效
    高亲和力小分子C5a受体调节剂

    公开(公告)号：US06723743B1

    公开(公告)日：2004-04-20

    申请号：US09672071

    申请日：2000-09-28

    申请人： Andrew Thurkauf ,  Xiao-shu He ,  He Zhao ,  John Peterson ,  Xiaoyan Zhang ,  Robbin Brodbeck ,  James Krause ,  George Maynard ,  Alan Hutchison

    发明人： Andrew Thurkauf ,  Xiao-shu He ,  He Zhao ,  John Peterson ,  Xiaoyan Zhang ,  Robbin Brodbeck ,  James Krause ,  George Maynard ,  Alan Hutchison

    IPC分类号： A61K31415

    CPC分类号： C07D207/327 ,  C07C233/11 ,  C07C233/22 ,  C07C233/65 ,  C07C233/66 ,  C07C233/73 ,  C07C233/78 ,  C07C235/46 ,  C07C235/48 ,  C07C235/54 ,  C07C235/60 ,  C07C235/62 ,  C07C235/66 ,  C07C237/20 ,  C07C323/62 ,  C07C2601/08 ,  C07C2601/14 ,  C07C2602/08 ,  C07C2602/10 ,  C07C2603/18 ,  C07D213/38 ,  C07D213/82 ,  C07D215/12 ,  C07D217/04 ,  C07D217/06 ,  C07D217/14 ,  C07D217/16 ,  C07D231/12 ,  C07D233/64 ,  C07D233/68 ,  C07D235/02 ,  C07D235/14 ,  C07D235/18 ,  C07D317/58 ,  C07D333/24 ,  C07D333/28 ,  C07D333/54 ,  C07D401/06 ,  C07D401/12 ,  C07D403/12 ,  C07D405/06 ,  C07D405/12 ,  C07D405/14 ,  C07D409/12 ,  C07D409/14 ,  C07D417/12 ,  C07D471/04

    摘要： This invention relates to low molecular weight, non-peptidic, non-peptidomimetic, organic molecules that act as modulators of mammalian complement C5a receptors, preferably ones that act as high affinity C5a receptor ligands and also to such ligands that act as antagonists or inverse agonists of complement C5a receptors, preferably human C5a receptors, Preferred compounds of the invention possess one or more, and preferably two or more, three or more, four or more, or all of the following properties in that they are; 1) multi-aryl in structure (having a plurality of un-fused or fused aryl groups), 2) heteroaryl in structure, 3) orally available in vivo (such that a sub-lethal or preferably a pharmaceutically acceptable oral dose can provide a detectable in vitro effect such as a reduction of C5a-induced neutropenia), 4) comprised of fewer than four, preferably fewer than three, or fewer than two, or no amide bonds, and 5) capable of inhibiting leukocyte chemotaxis at nanomolar concentrations and preferably at sub-nanomolar concentrations. Specifically exemplified representative compounds include, but are not limited to optionally substituted arylimidazoles, optionally substituted arylpyridyls, optionally substituted aryl-substituted cycloalkylimidazoles, optionally substituted arylpyrazoles, optionally substituted benzimidazoles, optionally substituted aryl-substituted tetrahydroisoquinolines, and optionally substituted biaryl carboxamides. This invention also relates to pharmaceutical compositions comprising such compounds. It further relates to the use of such compounds in treating a variety of inflammatory and immune system disorders. Additionally, this invention relates to the use such compounds as probes for the localization of C5a receptors.

    摘要翻译： 本发明涉及作为哺乳动物补体C5a受体调节剂的低分子量，非肽，非拟肽，有机分子，优选用作高亲和力C5a受体配体的调节剂，还涉及作为拮抗剂或反向激动剂的这些配体 的补体C5a受体，优选人C5a受体。本发明的优选化合物具有一个或多个，优选两个或更多个，三个或更多个，四个或更多个或全部以下性质： 1）结构上的多芳基（具有多个未稠合或稠合芳基），2）结构上的杂芳基，3）在体内可口服（使得亚致死或优选药学上可接受的口服剂量可提供 可检测的体外效应，例如C5a诱导的中性粒细胞减少的减少），4）由少于4个，优选少于3个，或少于2个或不存在的酰胺键组成，以及5）能够以纳摩尔浓度抑制白细胞趋化性， 优选亚纳摩尔浓度。 具体示例的代表性化合物包括但不限于任选取代的芳基咪唑，任选取代的芳基吡啶基，任选取代的芳基取代的环烷基咪唑，任选取代的芳基吡唑，任选取代的苯并咪唑，任选取代的芳基取代的四氢异喹啉和任选取代的双芳基甲酰胺。 本发明还涉及包含这些化合物的药物组合物。 它还涉及这些化合物在治疗各种炎性和免疫系统疾病中的应用。 此外，本发明涉及使用这些化合物作为C5a受体定位的探针。

    Key fob
    68.
    外观设计
    Key fob 失效
    钥匙扣

    公开(公告)号：USD461047S1

    公开(公告)日：2002-08-06

    申请号：US29136125

    申请日：2001-01-26

    申请人： John Peterson

    设计人： John Peterson

    Terminal block for circuit board
    69.
    发明授权
    Terminal block for circuit board 失效
    电路板接线端子

    公开(公告)号：US5902139A

    公开(公告)日：1999-05-11

    申请号：US954069

    申请日：1997-10-20

    申请人： John Peterson ,  David Saunders

    发明人： John Peterson ,  David Saunders

    IPC分类号： H01R12/55 ,  H05K3/34 ,  H01R9/09

    CPC分类号： H05K3/3405 ,  H01R12/7005 ,  H01R12/727 ,  H05K2201/10189 ,  H05K3/3447

    摘要： The terminal block of the present invention provides both a simple high strength mechanical connection with a circuit board as well as a good electrical connection. The terminal block has a snapfit with a side edge of the circuit board due to a cooperation between pins of the terminal block and holes through the circuit board. The terminal block simplifies assembly and improves the mechanical connection of the terminal block with the circuit board.

    摘要翻译： 本发明的接线端子既提供与电路板的简单的高强度机械连接以及良好的电连接。 由于端子块的引脚与穿过电路板的孔之间的协作，端子块具有带电路板的侧边缘的搭扣。 端子块简化组装，并改善端子块与电路板的机械连接。

    Test indicator control circuit for security alarm device
    70.
    发明授权
    Test indicator control circuit for security alarm device 失效
    用于安全报警装置的测试指示器控制电路

    公开(公告)号：US5898368A

    公开(公告)日：1999-04-27

    申请号：US46734

    申请日：1998-03-24

    申请人： Lucas Handley ,  John Peterson

    发明人： Lucas Handley ,  John Peterson

    IPC分类号： G08B29/14 ,  G08B29/00

    CPC分类号： G08B29/14

    摘要： An intrusion detector for monitoring a space has a sensor for generating detection signals in response to detections of events occurring in the space and an indicator for receiving the detection signals and for generating detection indications in response thereto. A controllable switch is operably interposed between the sensor and the indicator and operates to connect or disconnect the sensor and the indicator. A switch control circuit is connected to the switch. A test trigger device is connected to the control circuit to generate an initiate-test signal to the control circuit. The control circuit is also connected to the sensor and receives and counts detection signals. The control circuit controls the operation of the switch by generating a switch control signal in response to the initiate-test signal and to the counting of detection signals.

    摘要翻译： 用于监测空间的入侵检测器具有用于响应于在空间中发生的事件的检测而产生检测信号的传感器，以及用于接收检测信号的指示符并响应于此产生检测指示。 可控开关可操作地插入在传感器和指示器之间并且操作以连接或断开传感器和指示器。 开关控制电路连接到开关。 测试触发装置连接到控制电路以产生到控制电路的启动测试信号。 控制电路也连接到传感器并接收和计数检测信号。 控制电路通过响应于启动测试信号和检测信号的计数产生开关控制信号来控制开关的操作。