公开(公告)号：US20090187031A1

公开(公告)日：2009-07-23

申请号：US12072730

申请日：2008-02-28

申请人： Amos B. Smith, III ,  Thomas J. Beauchamp ,  Matthew J. LaMarche ,  Yuping Qiu ,  Michael D. Kaufman ,  Hirokazu Arimoto ,  David R. Jones ,  Kaoru Kobayashi

发明人： Amos B. Smith, III ,  Thomas J. Beauchamp ,  Matthew J. LaMarche ,  Yuping Qiu ,  Michael D. Kaufman ,  Hirokazu Arimoto ,  David R. Jones ,  Kaoru Kobayashi

IPC分类号： C07D309/30 ,  C07F7/08 ,  C07D319/06

CPC分类号： C07C271/12 ,  C07B2200/07 ,  C07D213/30 ,  C07D263/22 ,  C07D303/16 ,  C07D309/10 ,  C07D309/30 ,  C07D309/32 ,  C07D319/06 ,  C07D339/08 ,  C07D407/06 ,  C07D413/06 ,  C07D413/12 ,  C07D417/06 ,  C07F7/1804 ,  C07F7/1892 ,  C07F9/5428 ,  C07F9/5442

摘要： Synthetic methods and intermediates useful in the preparation of lactone containing compounds such as discodermolide and compounds which mimic the chemical or biological activity of discodermolide are provided.

摘要翻译： 提供了可用于制备含内酯化合物如discodermolide的合成方法和中间体以及模拟discodermolide的化学或生物活性的化合物。

公开(公告)号：US20090180525A1

公开(公告)日：2009-07-16

申请号：US12382157

申请日：2009-03-10

申请人： Kaoru Kobayashi ,  Shigeru Takegishi

发明人： Kaoru Kobayashi ,  Shigeru Takegishi

IPC分类号： H04B1/707

CPC分类号： H04B1/70752 ,  H04L27/0014 ,  H04L2027/0026 ,  H04L2027/0051 ,  H04L2027/0095

摘要： A signal processing unit and a wireless communication device are provided for making it possible to improve detecting sensitivity in correlation peak detecting processing. The signal processing unit and the wireless communication device are comprised of a carrier data generating unit; a carrier demodulation unit; a matched filter unit that carries out despread processing and full addition processing as partial correlation processing for carrier demodulated data, and outputs correlation peak detected data; a correlation peak detecting unit that detects a correlation peak from the correlation detected data and outputs correlation peak position information; a coarse frequency deviation detecting unit that detects a frequency component in accordance with a carrier frequency deviation amount with respect to the carrier demodulated data and outputs a frequency deviation amount to the carrier data generating unit; a fine frequency deviation detecting unit that outputs a fine frequency deviation amount to reduce the frequency deviation amount from the correlation detected data and the correlation peak position information to the carrier data generating unit; and a control unit that inputs the correlation peak position information and adjusts a processing clock signal.

摘要翻译： 提供信号处理单元和无线通信设备，用于提高相关峰值检测处理中的检测灵敏度。 信号处理单元和无线通信设备包括载波数据生成单元; 载波解调单元; 匹配滤波器单元，其执行解扩处理和全加法处理作为载波解调数据的部分相关处理，并输出相关峰检测数据; 相关峰值检测单元，根据相关检测数据检测相关峰值，并输出相关峰值位置信息; 粗频率偏差检测单元，根据与载波解调数据相关的载波频率偏差量检测频率分量，并向载波数据生成单元输出频率偏差量; 精细频率偏差检测单元，其将相关检测数据和相关峰值位置信息的频率偏差量的精细频率偏差量输出到载波数据生成单元; 以及控制单元，其输入相关峰值位置信息并调整处理时钟信号。

公开(公告)号：US20080197434A1

公开(公告)日：2008-08-21

申请号：US12101607

申请日：2008-04-11

申请人： Yoshihiro Kato ,  Katsumi Okayama ,  Kaoru Kobayashi ,  Tetsuya Yamamoto ,  Minoru Ikarashi

发明人： Yoshihiro Kato ,  Katsumi Okayama ,  Kaoru Kobayashi ,  Tetsuya Yamamoto ,  Minoru Ikarashi

IPC分类号： H01L23/552 ,  H01L29/82

CPC分类号： H01L23/49575 ,  H01L23/552 ,  H01L2924/0002 ,  H01L2924/00

摘要： A magnetic memory device in which an MRAM element is magnetically shielded from large external magnetic fields. The magnetic memory device includes: a substrate; a magnetic random access memory mounted on the substrate, the magnetic random access memory including a memory element having a magnetized pinned layer with fixed direction of magnetization and a magnetic layer with changeable direction of magnetization stacked on one another; another element mounted on the substrate; and a pair of magnetic shielding layers which magnetically shield the memory element, the magnetic shielding layers located relatively above and below the memory element and within a region corresponding to an area occupied by the memory element.

摘要翻译： 一种磁存储器件，其中MRAM元件与大的外部磁场磁屏蔽。 磁存储器件包括：基片; 安装在基板上的磁性随机存取存储器，所述磁性随机存取存储器包括具有固定磁化方向的磁化钉扎层和具有可变方向磁化的磁性层彼此叠置的存储元件; 安装在基板上的另一元件; 以及一对磁屏蔽层，其对存储元件进行磁屏蔽，磁屏蔽层位于相对于存储元件的上方和下方并且在对应于存储元件所占据的区域的区域内。

公开(公告)号：US07402605B2

公开(公告)日：2008-07-22

申请号：US10506536

申请日：2003-03-04

申请人： Kousuke Tani ,  Kaoru Kobayashi ,  Toru Maruyama ,  Tohru Kambe ,  Mikio Ogawa ,  Tsutomu Shiroya

发明人： Kousuke Tani ,  Kaoru Kobayashi ,  Toru Maruyama ,  Tohru Kambe ,  Mikio Ogawa ,  Tsutomu Shiroya

IPC分类号： A61K31/40 ,  C07D207/00

CPC分类号： C07D413/06 ,  C07D207/26 ,  C07D263/24 ,  C07D405/06 ,  C07D405/12 ,  C07D409/06 ,  C07D409/12 ,  C07D413/12 ,  C07D417/06 ,  C07D417/12

摘要： An 8-azaprostaglandin represented by formula (I) (wherein all symbols have the same meanings as described in the specification), a pharmaceutically acceptable salt thereof or a cyclodextrin clathrate thereof. Since the compound represented by formula (I) binds to EP2 subtype among PGE receptor strongly, it is useful for preventive and/or treatment for immune diseases, allergic diseases, neuronal cell death, dysmenorrhea, premature birth, abortion, baldness, retinal neuropathy such as glaucoma, erectile dysfunction, arthritis, pulmonary injury, pulmonary fibrosis, pulmonary emphysema, bronchitis, chronic obstructive pulmonary disease, hepatic injury, acute hepatitis, liver cirrhosis, shock, nephritis, renal failure, circulatory diseases, systemic inflammatory response syndrome, sepsis, hemophagocytosis syndrome, macrophage activation syndrome, still disease, Kawasaki Disease, burn, systemic granuloma, ulcerative colitis, Crohn disease, hypercytokinemia at dialysis, multiple organ failure, or bone diseases etc.

摘要翻译： 由式（I）（其中所有符号具有与说明书中所述相同的含义）表示的8-氮杂前列腺素，其药学上可接受的盐或其环糊精包合物。 由于式（I）表示的化合物强烈地与PGE受体中的EP2亚型结合，因此可用于免疫疾病，过敏性疾病，神经元细胞死亡，痛经，早产，流产，秃发，视网膜神经病变等的预防和/或治疗 青光眼，勃起功能障碍，关节炎，肺损伤，肺纤维化，肺气肿，支气管炎，慢性阻塞性肺病，肝损伤，急性肝炎，肝硬化，休克，肾炎，肾衰竭，循环系统疾病，全身炎症反应综合征，败血症， 血细胞增多综合征，巨噬细胞活化综合征，静止病，川崎病，烧伤，全身肉芽肿，溃疡性结肠炎，克罗恩病，透析中的高细胞因子血症，多器官功能衰竭或骨骼疾病等。

公开(公告)号：US20060045543A1

公开(公告)日：2006-03-02

申请号：US11185879

申请日：2005-07-21

申请人： Yoshihiro Kato ,  Yoshinori Ito ,  Katsumi Okayama ,  Kaoru Kobayashi ,  Masaki Orihashi ,  Makoto Suzuki ,  Takashi Miyazaki

发明人： Yoshihiro Kato ,  Yoshinori Ito ,  Katsumi Okayama ,  Kaoru Kobayashi ,  Masaki Orihashi ,  Makoto Suzuki ,  Takashi Miyazaki

IPC分类号： G03G15/00

CPC分类号： H05K9/0075

摘要： An electromagnetism suppressing material has an increased electromagnetism suppressing effect, can be flexibly formed in various shapes, and is inexpensive. An electromagnetism suppressing device uses the electromagnetism suppressing material, and an electronic appliance uses the electromagnetism suppressing material or the electromagnetism suppressing device. The electromagnetism suppressing material is a liquid material and/or gel material with electrical polarity.

摘要翻译： 电磁抑制材料具有增加的电磁抑制效果，可以灵活地形成各种形状，并且便宜。 电磁抑制装置使用电磁抑制材料，电子设备使用电磁抑制材料或电磁抑制装置。 电磁抑制材料是具有电极性的液体材料和/或凝胶材料。

公开(公告)号：US06992155B2

公开(公告)日：2006-01-31

申请号：US10245046

申请日：2002-09-17

申请人： Katsumi Okayama ,  Kaoru Kobayashi ,  Koichiro Inomata ,  Satoshi Sugimoto ,  Yoshihiro Kato

发明人： Katsumi Okayama ,  Kaoru Kobayashi ,  Koichiro Inomata ,  Satoshi Sugimoto ,  Yoshihiro Kato

IPC分类号： C08F4/42 ,  C08K3/10 ,  C08K3/18 ,  B32B15/02 ,  B32B15/08

CPC分类号： B82Y30/00 ,  B22F1/0018 ,  B22F1/0059 ,  B22F9/24 ,  B22F9/305 ,  B22F2998/00 ,  B82Y25/00 ,  B82Y40/00 ,  C22C32/0094 ,  H01F1/0054 ,  H01F41/30 ,  H01F41/301 ,  Y10S977/777 ,  Y10S977/783 ,  Y10T428/12146 ,  Y10T428/254 ,  Y10T428/256 ,  Y10T428/257 ,  Y10T428/29 ,  Y10T428/2991 ,  Y10T428/2998 ,  B22F3/02

摘要： A method for producing a magnetic particle forming a magnetic material for absorbing electromagnetic waves comprises the steps of mixing an organometallic complex or a metal salt with a chain polymer and dissolving the mixture in a solvent (step S1); raising the temperature of the mixture to reaction temperature (step S2), carrying out a reaction at the reaction temperature (step S3); and forming the magnetic particle having a structure that the periphery of each fine particle formed from the organometallic complex or the metal salt is surrounded by the chain polymer and recovering the formed magnetic particle after the reaction (step S4). The magnetic particle has a nanogranular structure to become a magnetic material for absorbing electromagnetic waves. Such a magnetic particle is produced by a wet reaction. Thus, a larger amount of magnetic particle can be produced by one reaction.

摘要翻译： 形成用于吸收电磁波的磁性材料的磁性颗粒的制造方法包括将有机金属络合物或金属盐与链状聚合物混合并将该混合物溶解在溶剂中的步骤（步骤S1）。 将混合物的温度升至反应温度（步骤S2），在反应温度下进行反应（步骤S3）; 并形成具有由有机金属配合物或金属盐形成的各微细颗粒的周围被链状聚合物包围并在反应后回收形成的磁性颗粒的结构的磁性颗粒（步骤S4）。 磁性颗粒具有纳米结构，成为吸收电磁波的磁性材料。 这样的磁性颗粒是通过湿反应产生的。 因此，通过一次反应可以产生更大量的磁性颗粒。

公开(公告)号：US20050124672A1

公开(公告)日：2005-06-09

申请号：US10471673

申请日：2002-03-11

申请人： Atsushi Naganawa ,  Tetsuji Saito ,  Kaoru Kobayashi ,  Takayuki Maruyama ,  Yoshihiko Nakai ,  Shinsuke Hashimoto

发明人： Atsushi Naganawa ,  Tetsuji Saito ,  Kaoru Kobayashi ,  Takayuki Maruyama ,  Yoshihiko Nakai ,  Shinsuke Hashimoto

IPC分类号： C07D307/64 ,  A61K31/34 ,  A61K31/341 ,  A61K31/41 ,  A61K31/4245 ,  A61K31/426 ,  A61K31/427 ,  A61K31/4402 ,  A61K31/4406 ,  A61K31/4439 ,  A61P1/04 ,  A61P13/00 ,  A61P13/02 ,  A61P29/00 ,  A61P35/00 ,  A61P43/00 ,  C07D213/70 ,  C07D213/71 ,  C07D277/20 ,  C07D277/36 ,  C07D401/12 ,  C07D405/12 ,  C07D413/12 ,  C07D417/12

CPC分类号： C07D213/70 ,  C07D277/36 ,  C07D307/64 ,  C07D401/12 ,  C07D405/12 ,  C07D413/12 ,  C07D417/12

摘要： An N-phenylarylsulfonylamide compound of formula (I) (R1 is COOH etc.; R2 is hydrogen, methyl, etc.; R3 and R4 are a combination of methyl and methyl, etc.; R5 is isopropyl etc.; Ar is thiazolyl, pyridyl, 5-methyl-2-furyl each optionally substituted with methyl; n is zero or 1), a synthetic intermediate for the compound and a process for its preparation. The compound of formula (I) binds to a prostaglandin E2 receptor, especially an EP1 subtype receptor, and antagonizes it. It is less affected by protein binding, so it has a satisfactory in vivo activity. Therefore, it is considered to be useful as an analgesic, an antipyretic agent, an agent for the treatment of pollakiuria (frequent urination) and/or lower urinary tract disease syndrome or an antineoplastic agent.

摘要翻译： 式（I）的N-苯基芳基磺酰胺化合物（R 1）是COOH等; R 2是氢，甲基等; R 3 O >和R 4是甲基和甲基等的组合; R 5是异丙基等; Ar是噻唑基，吡啶基，5-甲基-2-呋喃基 任选被甲基取代; n为0或1），化合物的合成中间体及其制备方法。 式（I）化合物与前列腺素E 2受体结合，特别是EP 1亚型受体，并拮抗它。 蛋白质结合的影响较小，因此具有令人满意的体内活性。 因此，认为可用作止痛剂，解热剂，治疗尿频（尿频）和/或下尿路疾病综合征或抗肿瘤药物的药剂。

公开(公告)号：US20050004097A1

公开(公告)日：2005-01-06

申请号：US10488835

申请日：2002-09-06

申请人： Kazuhiko Torisu ,  Maki Iwahashi ,  Kaoru Kobayashi ,  Fumio Nambu

发明人： Kazuhiko Torisu ,  Maki Iwahashi ,  Kaoru Kobayashi ,  Fumio Nambu

IPC分类号： A61K31/404 ,  A61K31/405 ,  A61K31/4155 ,  A61K31/4178 ,  A61K31/422 ,  A61K31/423 ,  A61K31/427 ,  A61K31/4439 ,  A61K31/454 ,  A61K31/4709 ,  A61K31/497 ,  A61K31/498 ,  A61K31/5377 ,  A61K31/538 ,  A61K31/5383 ,  A61K31/5415 ,  C07D209/08 ,  C07D401/12 ,  C07D403/12 ,  C07D405/12 ,  C07D409/12 ,  C07D411/12 ,  C07D413/12 ,  C07D417/12 ,  C07D498/04 ,  C07

CPC分类号： A61K31/405 ,  A61K31/404 ,  A61K31/4155 ,  A61K31/4178 ,  A61K31/422 ,  A61K31/423 ,  A61K31/427 ,  A61K31/4439 ,  A61K31/454 ,  A61K31/4709 ,  A61K31/497 ,  A61K31/498 ,  A61K31/5377 ,  A61K31/538 ,  A61K31/5383 ,  A61K31/5415 ,  C07D209/08 ,  C07D401/12 ,  C07D403/12 ,  C07D405/12 ,  C07D409/12 ,  C07D411/12 ,  C07D413/12 ,  C07D417/12

摘要： Compounds represented by formula (I) wherein all symbols represent the same meanings as described in specification. and salts thereof. Since the compound represented by the formula (I) binds and antagonizes to DP receptor, it is useful for the prevention or treatment against the disease such as allergic disorder, diseases accompanied with itching, secondary diseases generated by behaviors caused by itching, inflammation, chronic obstructive pulmonary disease, ischemic reperfusion disorder, pleuritis complicated by rheumatoid arthritis, cerebrovascular disease, and ulcerative colitis.

摘要翻译： 由式（I）表示的化合物，其中所有符号表示与说明书中所述相同的含义。 及其盐。 由于式（I）表示的化合物与DP受体结合并拮抗，因此可用于预防或治疗诸如过敏性疾病，伴有瘙痒的疾病，由瘙痒引起的行为引起的继发性疾病，炎症，慢性 阻塞性肺病，局部缺血再灌注障碍，类风湿关节炎并发的胸膜炎，脑血管疾病和溃疡性结肠炎。

公开(公告)号：US5621130A

公开(公告)日：1997-04-15

申请号：US141630

申请日：1993-10-27

申请人： Wataru Ando ,  Takeshi Akasaka ,  Shigeru Nagase ,  Kaoru Kobayashi ,  Hajime Miyazaki

发明人： Wataru Ando ,  Takeshi Akasaka ,  Shigeru Nagase ,  Kaoru Kobayashi ,  Hajime Miyazaki

IPC分类号： B82B1/00 ,  G03G5/05 ,  G03G5/06 ,  C07F7/08 ,  C07F7/18

CPC分类号： G03G5/062 ,  G03G5/0578 ,  G03G5/0605 ,  G03G5/0642

摘要： A photosensitive member having stable electrophotographic characteristics can be constituted by an electroconductive support and a photosensitive layer disposed thereon and containing a novel fullerene compound having an organosilicon group as a charge-transporting substance. The fullerene compound may preferably have a polyhedral structure, particularly that of Buckminsterfullerene (C.sub.60) and be represented by the formula: C.sub.60 (A).sub.n . . . (2), wherein A denotes an organosilicon group represented by the formula: ##STR1## (wherein R.sub.1-1 and R.sub.1-2 independently denote a hydrogen atom, a substituted or unsubstituted alkyl group, a substituted or unsubstituted aryl group, a substituted or unsubstituted alkoxy group, a substituted or unsubstituted silyl group, a substituted or unsubstituted germyl group, a halogen atom, or a group constituting a substituted or unsubstituted ring by a mutual combination of R.sub.1-1 and R.sub.1-2 together with the Si atom in the formula); and n is an integer of 1 to 5, and a plurality of A in the case of n being two or larger can be the same or different with each other.

摘要翻译： 具有稳定的电子照相特性的感光构件可由导电载体和设置在其上的感光层构成，并含有具有有机硅基团的新型富勒烯化合物作为电荷输送物质。 富勒烯化合物可以优选具有多面体结构，特别是Buckminsterfullerene（C60）的多面体结构，并由下式表示：C60（A）n。 。 。 （2）其中A表示由下式表示的有机硅基团：（1）（其中R1-1和R1-2独立地表示氢原子，取代或未取代的烷基，取代或未取代的芳基， 取代或未取代的烷氧基，取代或未取代的甲硅烷基，取代或未取代的锗基，卤素原子或构成取代或未取代的环的基团，通过R 1和R 2的相互组合与Si 原子在式中）; n为1〜5的整数，n为2以上的情况下的多个A可以相同或不同。

公开(公告)号：US5290969A

公开(公告)日：1994-03-01

申请号：US619202

申请日：1990-11-28

申请人： Kaoru Kobayashi

发明人： Kaoru Kobayashi

IPC分类号： G10H1/00 ,  G10H5/00 ,  G10H7/00 ,  G10H7/08 ,  G10H1/12

CPC分类号： G10H5/007 ,  G10H2250/451 ,  G10H2250/515 ,  G10H2250/521 ,  Y10S84/10 ,  Y10S84/26

摘要： A musical tone synthesizing apparatus generates musical tones by simulating the tone generation construction of a plucked-stringed instrument or percussion type stringed instrument. The apparatus has a plurality of closed loop circuits which simulate each tone generating element of the instrument, an excitation circuit which creates an excitation signal corresponding to the excitation given to the plurality of tone generating elements in response to the operation of a tone generating operator or the operational information of the tone generating operator, and a memory which stores a non-linear relation between the tone generating elements and the tone generating operator such as a hammer. The excitation signal is supplied to each of the closed loop circuits and circulates around each closed loop circuit and is delayed by means of a delay circuit having delay interval, and is fed back into the excitation circuit as the state of the tone generating elements. By varying the delay time of each delay circuit, the beat between the musical tones taken out from each closed loop circuit can be generated.

摘要翻译： 乐音合成装置通过模拟采摘乐器或打击乐弦乐器的乐音产生结构来产生乐音。 该装置具有模拟仪器的每个乐音产生元件的多个闭环电路，激励电路，响应于乐音发生操作者的操作，产生与给予多个乐音发生元件的激励相对应的激励信号， 乐音发生操作者的操作信息，以及存储音乐发生元件和音调生成操作者之类的诸如锤子之间的非线性关系的存储器。 激励信号被提供给每个闭环电路并在每个闭环电路周围循环，并且借助于具有延迟间隔的延迟电路被延迟，并且作为音调发生元件的状态被反馈到激励电路中。 通过改变每个延迟电路的延迟时间，可以产生从每个闭环电路取出的乐音之间的节拍。