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    Optical character generator for an electrographic printer
    61.
    发明授权
    Optical character generator for an electrographic printer 失效
    用于电印机的光学字符发生器

    公开(公告)号：US5874984A

    公开(公告)日：1999-02-23

    申请号：US495592

    申请日：1995-08-02

    申请人： Christian Scholz ,  Manfred Wiedemer

    发明人： Christian Scholz ,  Manfred Wiedemer

    IPC分类号： B41J2/44 ,  B41J2/45 ,  B41J2/455 ,  H01L27/15 ,  B41J2/47 ,  B41J2/435

    CPC分类号： H01L27/153 ,  B41J2/45 ,  H01L2224/05553 ,  H01L2224/05554 ,  H01L2224/48091 ,  H01L2224/48137 ,  H01L2224/49175 ,  H01L27/156

    摘要： An optical character generator for an electrographic printer has a plurality of monolithic circuits (11) which are arranged on a carrier (10) and have LEDs (12) which are integrated in the circuits and can be driven individually. The monolithic circuits (11) include a monolithically integrated photodiode drive combination, in the case of which both the associated LEDs (12) and the drive circuit (13), possibly including a BUS circuit (14) for the LEDs (12), are integrated in a monolithic circuit (11). The monolithic circuits are constructed using thin-film technology from III-V semiconductor material, preferably GaAs.

    摘要翻译： PCT No.PCT / DE94 / 00097 Sec。 371日期：1995年8月2日 102（e）日期1995年8月2日PCT 1994年2月1日PCT PCT。 出版物WO94 / 18704 日期1994年8月18日用于电印机的光学字符发生器具有多个单片电路（11），其布置在载体（10）上并具有集成在电路中并可单独驱动的LED（12）。 在其中可能包括用于LED（12）的BUS电路（14）的相关联的LED（12）和驱动电路（13）两者都是相同的情况下，单片电路（11）包括单片集成的光电二极管驱动组合 集成在单片电路（11）中。 使用来自III-V半导体材料（优选GaAs）的薄膜技术构建单片电路。

    SLPA AS A TOOL FOR RECOMBINANT PROTEIN AND ENZYME TECHNOLOGY
    62.
    发明申请
    SLPA AS A TOOL FOR RECOMBINANT PROTEIN AND ENZYME TECHNOLOGY 有权
    SLPA作为重组蛋白和酶技术的工具

    公开(公告)号：US20120308994A1

    公开(公告)日：2012-12-06

    申请号：US13569353

    申请日：2012-08-08

    申请人： Christian Scholz ,  Elke Faatz ,  Urban Schmitt ,  Peter Schaarschmidt

    发明人： Christian Scholz ,  Elke Faatz ,  Urban Schmitt ,  Peter Schaarschmidt

    IPC分类号： G01N21/76 ,  G01N33/569

    CPC分类号： C12N15/62 ,  C12N9/90 ,  G01N33/536 ,  G01N33/54393 ,  Y02A50/57

    摘要： Disclosed are a recombinant DNA molecule encoding a fusion protein comprising a SlpA chaperone and a target polypeptide wherein human FK506 binding proteins (FKBPs) are excluded as target polypeptides, a corresponding expression vector encoding said fusion protein as well as host cells transformed with said expression vector. Also disclosed are a method for producing the fusion protein, a recombinantly produced fusion protein comprising a SlpA chaperone and a target polypeptide. A further aspect of the invention is the use of the recombinantly produced fusion protein, and a reagent kit containing a recombinantly produced fusion protein comprising a SlpA chaperone and a target polypeptide.

    摘要翻译： 公开了编码包含SlpA伴侣和靶多肽的融合蛋白的重组DNA分子，其中人FK506结合蛋白（FKBP）被排除为靶多肽，编码所述融合蛋白的相应表达载体以及用所述表达载体转化的宿主细胞 。 还公开了产生融合蛋白的方法，重组产生的包含SlpA伴侣和靶多肽的融合蛋白。 本发明的另一方面是使用重组产生的融合蛋白，以及含有重组产生的包含SlpA伴侣和靶多肽的融合蛋白的试剂盒。

    FUSION PROTEIN COMPRISING AN E. COLI CHAPERONE PROTEIN AND A HUMAN CHAPERONE PROTEIN
    63.
    发明申请
    FUSION PROTEIN COMPRISING AN E. COLI CHAPERONE PROTEIN AND A HUMAN CHAPERONE PROTEIN 有权
    包含大肠杆菌蛋白和蛋白质的融合蛋白

    公开(公告)号：US20110189754A1

    公开(公告)日：2011-08-04

    申请号：US13083903

    申请日：2011-04-11

    申请人： Christian Scholz ,  Elke Faatz ,  Peter Schaarschmidt ,  Urban Schmitt

    发明人： Christian Scholz ,  Elke Faatz ,  Peter Schaarschmidt ,  Urban Schmitt

    IPC分类号： C12N9/96 ,  C07H21/04

    CPC分类号： C12N9/90 ,  C07K2319/35

    摘要： The invention discloses the cloning, expression and uses of a chimeric fusion protein with superior chaperone and folding activities compared to the wild type chaperones. This invention relates to a chimeric fusion protein encoded by a recombinant DNA molecule containing nucleotide sequences coding for a polypeptide binding segment of a non-human chaperone protein and nucleotide sequences coding for an FK506 binding protein (FKBP) or an FK506-binding-protein-like domain (FKBP-like domain). In particular, this invention relates to a chimeric fusion protein encoded by a recombinant DNA molecule containing nucleotide sequences coding for a polypeptide binding segment of a non-human chaperone protein and nucleotide sequences coding for a human FKBP type peptidyl-prolyl-cis/trans isomerase (PPIase), methods of producing these chimeric fusion proteins and their uses as folding helpers in the production of other proteins and in the process of the production of vaccines or pharmaceuticals, and as folding helpers for performing immunoassays.

    摘要翻译： 本发明公开了与野生型伴侣相比，具有优异的伴侣和折叠活性的嵌合融合蛋白的克隆，表达和用途。 本发明涉及由含有编码非人伴侣蛋白多肽结合片段的核苷酸序列的重组DNA分子编码的嵌合融合蛋白和编码FK506结合蛋白（FKBP）或FK506-结合蛋白 - 像域（FKBP样域）。 特别地，本发明涉及由包含编码非人伴侣蛋白多肽结合片段的核苷酸序列的重组DNA分子编码的嵌合融合蛋白和编码人FKBP型肽基 - 脯氨酰 - 顺/反异构酶的核苷酸序列 （PPIase），生产这些嵌合融合蛋白的方法及其在生产其他蛋白质和疫苗或药物生产过程中作为折叠助剂的用途，以及用于进行免疫测定的折叠助剂。

    Soluble rubella E1 envelope protein variants
    67.
    发明申请
    Soluble rubella E1 envelope protein variants 有权
    可溶性风疹E1包膜蛋白变体

    公开(公告)号：US20070154883A1

    公开(公告)日：2007-07-05

    申请号：US11584887

    申请日：2006-10-23

    申请人： Barbara Upmeier ,  Ralf Bollhagen ,  Alfred Engel ,  Elke Faatz ,  Peter Schaarschmidt ,  Christian Scholz ,  Toralf Zarnt

    发明人： Barbara Upmeier ,  Ralf Bollhagen ,  Alfred Engel ,  Elke Faatz ,  Peter Schaarschmidt ,  Christian Scholz ,  Toralf Zarnt

    IPC分类号： C12Q1/70

    CPC分类号： C07K14/005 ,  C07K2319/35 ,  C12N2770/36222 ,  Y10S530/826

    摘要： The invention disclosed relates to a soluble rubella E1 antigen and variants of this peptide characterized by lacking at the C-terminal end at least the transmembrane region and the anchor segment as well as at least the amino acids 143 to 164 and containing at least the region spanning the disulfide bridges Cys 349-Cys 352 and Cys 368-401 whereas the N-terminus (Cys 349) of this region contains additionally at least 15 amino acids and/or the C-terminus (Cys 401) of this region contains additionally at least 8 amino acids of the adjacent rubella E1 antigen sequence. Also described are a recombinant DNA molecule encoding the rubella E1 antigen and variants which are recombinantly expressed as a chaperone fusion protein, refolded into a soluble and immunoreactive conformation, and further used for the serological detection of anti-rubella antibodies. In addition, also disclosed is a method for the detection, determination and quantification of anti-rubella antibodies of IgG and/or IgM subclass in a sample wherein the rubella E1 antigen is used as a capture reagent and/or binding partner for the antibodies.

    摘要翻译： 所公开的本发明涉及可溶性风疹E1抗原和该肽的变体，其特征在于至少在C-末端缺少至少跨膜区和锚段以及至少氨基酸143至164并且至少含有该区域 跨越二硫键Cys 349-Cys 352和Cys 368-401，而该区域的N末端（Cys 349）另外包含至少15个氨基酸和/或该区域的C末端（Cys 401） 相邻风疹E1抗原序列的至少8个氨基酸。 还描述了编码风疹E1抗原的重组DNA分子和重组表达为伴侣融合蛋白的变体，重新折叠成可溶性和免疫反应性构象，并进一步用于抗风疹抗体的血清学检测。 此外，还公开了用于检测，测定和定量样品中IgG和/或IgM亚类的抗风疹抗体的方法，其中所述风疹E1抗原用作抗体的捕获试剂和/或结合配偶体。

    Method and device for controlling a print process with high color density
    68.
    发明授权
    Method and device for controlling a print process with high color density 失效
    用于控制具有高色密度的打印处理的方法和装置

    公开(公告)号：US07016620B2

    公开(公告)日：2006-03-21

    申请号：US10486372

    申请日：2002-07-24

    申请人： Volkhard Maess ,  Hans Winter ,  Christian Scholz

    发明人： Volkhard Maess ,  Hans Winter ,  Christian Scholz

    IPC分类号： G03G15/043

    CPC分类号： G03G15/0855 ,  G03G15/5041 ,  G03G2215/00042

    摘要： In a method and device to control a print process in a printer or copier, with a character generator generating a latent print image and a latent toner marking on an image carrier. An exposure energy per unit area for the generation of the latent toner marking is decreased in comparison to an energy per unit area for generation of the latent print image. The latent print image and the latent toner marking are developed with toner in the developer station. An optical reflection sensor determines color density of the developed toner marking. Toner concentration is adjusted in a developer station dependent on a signal of the reflection sensor.

    摘要翻译： 在用于控制打印机或复印机中的打印处理的方法和装置中，在图像载体上产生潜在打印图像和潜在墨粉标记的字符发生器。 潜在调色剂标记的产生的每单位面积的曝光能量相对于潜像印刷图像的每单位面积的能量而降低。 在显影剂站中用调色剂显影潜影图像和潜在调色剂标记。 光学反射传感器确定显影的调色剂标记的色彩浓度。 取决于反射传感器的信号，在显影剂站中调节调色剂浓度。

    Method for structuring a copper and/or permalloy layer by means of dry etching
    70.
    发明授权
    Method for structuring a copper and/or permalloy layer by means of dry etching 失效
    通过干蚀刻来构造铜和/或坡莫合金层的方法

    公开(公告)号：US4838994A

    公开(公告)日：1989-06-13

    申请号：US602307

    申请日：1988-06-06

    申请人： Peter Gulde ,  Christian Scholz

    发明人： Peter Gulde ,  Christian Scholz

    IPC分类号： G11B5/31 ,  H01F41/34

    CPC分类号： G11B5/3163 ,  H01F41/34

    摘要： A copper and/or permalloy layer is structured by means of dry etching. A layer of tantalum is applied as a mask to a layer to be structured, and a photoresist layer is applied to the tantalum layer. Subsequently, the structure of the photoresist layer generated in a photolithographic manner is transferred onto the mask by reactive ion etching. This procedure is continued until the copper or permalloy layer to be structured is exposed. The structuring of the copper or permalloy layer then occurs by ion beam etching.

    摘要翻译： 通过干蚀刻来构造铜和/或坡莫合金层。 将一层钽作为掩模施加到待构造的层上，并且将光致抗蚀剂层施加到钽层。 随后，通过反应离子蚀刻将以光刻方式生成的光致抗蚀剂层的结构转移到掩模上。 继续该程序直到暴露出要结构的铜或坡莫合金层。 然后通过离子束蚀刻发生铜或坡莫合金层的构造。