Continuous manufacturing method for microspheres and apparatus
    65.
    发明授权
    Continuous manufacturing method for microspheres and apparatus 失效
    微球的连续制造方法及其设备

    公开(公告)号:US06177479B1

    公开(公告)日:2001-01-23

    申请号:US09260412

    申请日:1999-03-01

    IPC分类号: B01F308

    摘要: In an apparatus for continuously manufacturing microspheres, a dispersed phase (O) is supplied to a chamber 27 for the dispersed phase inside of a bulkhead member 26 via a supply port 23. Thereafter, the dispersed phase enters into a gap 31 between a plate 22 via a supply port 29 in a base 25. The dispersed phase which enters into the gap 31 grows microspheres (particles) having a certain diameter while passing through a microchannel 33 by pressure applied by, for example, a pump, and is mixed with a continuous phase (W), so that microspheres are produced. The thus-produced microspheres float or are suspended in the continuous phase without needing any particular external force in response to their specific gravity, allowing the microspheres to be generated and withdrawn from a withdrawal port 32 at a significantly reduced pressure in comparison to conventional methods and apparatus.

    摘要翻译: 在用于连续制造微球体的装置中,分散相(O)经由供给口23供应到隔板部件26内的分散相的室27.此后,分散相进入板22之间的间隙31 通过基底25中的供给口29.通过例如由泵施加的压力通过微通道33,进入间隙31的分散相生长具有一定直径的微球(颗粒),并与 连续相(W),使得产生微球体。 如此生产的微球体在连续相中漂浮或悬浮,而不需要任何特定的外力作为响应其比重,从而与常规方法相比,以显着降低的压力从取出口32产生和取出微球,并且 仪器。