Cyclosporin analogues
    62.
    发明授权
    Cyclosporin analogues 有权
    环孢菌素类似物

    公开(公告)号:US08685917B2

    公开(公告)日:2014-04-01

    申请号:US12832316

    申请日:2010-07-08

    IPC分类号: A01N37/18 A61K38/04

    CPC分类号: C07K7/645

    摘要: The present invention provides novel cyclosporin analogue compounds, pharmaceutical compositions comprising these compounds and methods of using these compounds for the treatment of disorders and diseases, including immune disorders, inflammatory disorders and viral infections.

    摘要翻译: 本发明提供新的环孢菌素类似物化合物,包含这些化合物的药物组合物和使用这些化合物治疗疾病和疾病(包括免疫疾病,炎性疾病和病毒感染)的方法。

    Teaching apparatus for enterprise input-output
    64.
    发明授权
    Teaching apparatus for enterprise input-output 失效
    企业投入产出教学仪器

    公开(公告)号:US08475169B2

    公开(公告)日:2013-07-02

    申请号:US13032411

    申请日:2011-02-22

    申请人: Guoqiang Wang

    发明人: Guoqiang Wang

    IPC分类号: G09B19/18

    CPC分类号: G09B19/18 G09B25/02

    摘要: A teaching apparatus for enterprise input-output includes a base, said base defining a market system; a first block body defining a management module; a plurality of bands defining a production system and a product development system module, and a business system module, each band being sandwiched between two adjacent cuboids of the first block body; a vertical column defining a planning system module; a second block body defining a strategy module; a reverse quadrangle cone defining an information processing module; a cuboid vertical column disposed at a top of the reverse quadrangle cone; and a core solid column defining an internal information system, the core solid column penetrating through a center of the first block body, the bands, the vertical column, the second block body, the reverse quadrangle cone, and the cuboid vertical column.

    摘要翻译: 一种用于企业输入输出的教学装置,包括一个基地,该基地定义一个市场系统; 定义管理模块的第一块体; 限定生产系统和产品开发系统模块的多个带,以及商业系统模块,每个带夹在第一块体的两个相邻立方体之间; 定义规划系统模块的垂直列; 定义策略模块的第二块体; 定义信息处理模块的反向四角锥; 设置在反四边形锥体顶部的长方体立柱; 以及定义内部信息系统的核心固体柱,穿过第一块体的中心,带,垂直柱,第二块体,反向四边形锥体和长方体垂直柱的核心实心柱。

    Traffic Engineering and Server Selection for Content Distribution
    67.
    发明申请
    Traffic Engineering and Server Selection for Content Distribution 有权
    内容分发的流量工程和服务器选择

    公开(公告)号:US20120002542A1

    公开(公告)日:2012-01-05

    申请号:US13012500

    申请日:2011-01-24

    IPC分类号: H04L12/56

    摘要: An apparatus comprising a traffic engineering (TE) and server selection (SS) component configured to couple to an SS component and operate at a first time scale based on SS policies from the SS component, wherein the SS is configured to operate at a second timescale based on TE policies from the TE and SS component, and wherein the second timescale has a finer time granularity than the first time scale by at least one order of magnitude. Also disclosed is a network component comprising a receiver configured to receive one or more SS policies from a content provider or customer node, a logic circuit configured to compute a plurality of joint TE and SS policies for a plurality of network nodes based on the received SS policies, and a transmitter configured to send the joint TE and SS components to the content provider or customer node.

    摘要翻译: 一种包括业务工程(TE)和服务器选择(SS)组件的设备,其被配置为耦合到SS组件并且基于来自所述SS组件的SS策略以第一时标操作,其中所述SS被配置为在第二时间尺度 基于来自TE和SS分量的TE策略,并且其中所述第二时间尺度具有比所述第一时间尺度更精细的时间粒度至少一个数量级。 还公开了一种网络组件,包括被配置为从内容提供商或客户节点接收一个或多个SS策略的接收器,逻辑电路,被配置为基于所接收的SS来计算多个网络节点的多个联合TE和SS策略 策略和被配置为将联合TE和SS组件发送到内容提供商或客户节点的发射机。

    6-11 Bridged Oxime Erythromycin Derivatives
    70.
    发明申请
    6-11 Bridged Oxime Erythromycin Derivatives 审中-公开
    6-11桥接肟红霉素衍生物

    公开(公告)号:US20080262208A1

    公开(公告)日:2008-10-23

    申请号:US12123874

    申请日:2008-05-20

    IPC分类号: C07H17/08

    CPC分类号: C07H17/08

    摘要: The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes processes by which to make the compounds of the present invention.

    摘要翻译: 本发明公开了式I化合物或其药学上可接受的盐,酯或前药:其表现出抗菌性质。 本发明还涉及包含上述化合物的药物组合物,用于给予需要抗生素治疗的受试者。 本发明还涉及通过施用包含本发明化合物的药物组合物来治疗受试者的细菌感染的方法。 本发明还包括制备本发明化合物的方法。