公开(公告)号：US09119538B2

公开(公告)日：2015-09-01

申请号：US13720147

申请日：2012-12-19

申请人： Chisato Uesaka ,  Yukiya Sawanoi ,  Hiroyuki Kinoshita

发明人： Chisato Uesaka ,  Yukiya Sawanoi ,  Hiroyuki Kinoshita

IPC分类号： A61B5/0225 ,  A61B5/022 ,  A61B5/0235 ,  A61B5/00

CPC分类号： A61B5/0225 ,  A61B5/02233 ,  A61B5/0235 ,  A61B5/6824

摘要： A CPU of a sphygmomanometer includes a first control unit that, during measurement, controls a change in the internal pressure of a measurement air bladder by controlling the driving of a pump and/or a valve. The CPU further includes a second control unit that controls a change in the internal pressure of a compressing air bladder by controlling the driving of a pump and/or a valve. During measurement, the second control unit carries out control so that the internal pressure of the compressing air bladder is a predetermined ratio to the internal pressure of the measurement air bladder controlled by the first control unit.

摘要翻译： 血压计的CPU包括第一控制单元，其在测量期间通过控制泵和/或阀的驱动来控制测量气囊的内部压力的变化。 CPU还包括第二控制单元，其通过控制泵和/或阀的驱动来控制压缩空气囊的内部压力的变化。 在测量期间，第二控制单元执行控制，使得压缩空气囊的内部压力与由第一控制单元控制的测量空气囊的内部压力成预定比率。

公开(公告)号：US09107588B2

公开(公告)日：2015-08-18

申请号：US13965058

申请日：2013-08-12

申请人： Tensys Medical, Inc.

发明人： Andrew S. Katayama ,  Todd A. Keitel ,  Manouchehr Goharlaee ,  Stuart L. Gallant ,  Warren B. Craycroft

IPC分类号： A61B5/021 ,  A61B5/0225 ,  A61B5/00

CPC分类号： A61B5/0225 ,  A61B5/021 ,  A61B5/02233 ,  A61B5/6843 ,  A61B5/72

摘要： Improved apparatus and methods for non-invasively assessing one or more parameters associated with systems such as fluidic circulating systems (e.g., the circulatory system of a living organism). In a first aspect, an improved method of continuously measuring pressure from a compressible vessel is disclosed, wherein a substantially optimal level of compression for the vessel is achieved and maintained using dynamically applied dither perturbations (e.g., modulation) on the various axes associated with the vessel. In a second aspect, an improved apparatus and method are provided for monitoring hemodynamic parameters, such as blood pressure, in a continuous and non-invasive manner while operating under a single unifying scheme. One variant of this scheme using a simulated annealing (SA) type approach to determining and maintaining an optimal operating state.

摘要翻译： 用于非侵入性评估与系统如流体循环系统（例如，活体的循环系统）相关联的一个或多个参数的改进的装置和方法。 在第一方面，公开了一种从可压缩容器连续测量压力的改进方法，其中使用动态施加的抖动扰动（例如调制）在与 船只。 在第二方面，提供了一种改进的装置和方法，用于在单一统一方案下操作时以连续和非侵入方式监测血液动力学参数，例如血压。 该方案的一个变型使用模拟退火（SA）类型方法来确定和维持最佳操作状态。

公开(公告)号：US09072436B2

公开(公告)日：2015-07-07

申请号：US13044231

申请日：2011-03-09

申请人： Tatsuya Kobayashi ,  Hideaki Yoshida

发明人： Tatsuya Kobayashi ,  Hideaki Yoshida

IPC分类号： A61B5/02 ,  A61B5/0225 ,  A61B5/021 ,  A61B8/04

CPC分类号： A61B5/0225 ,  A61B5/02 ,  A61B5/021 ,  A61B5/02141 ,  A61B8/04

摘要： A measurement device includes an air bag on a peripheral side, an air bag on a central side, and an air bag positioned therebetween. During blood pressure measurement, the air bags integrally behave, and the blood pressure is measured from the change in inner pressure thereof. During pulse wave measurement, the inner pressure of the air bag on the peripheral side is maintained to higher than or equal to the systolic blood pressure, and the measurement site is avascularized. The inner pressure of the air bag on the central side is maintained to the pressure near the blood pressure value, and the pulse wave is measured from the change in inner pressure thereof. The inner pressure of the air bag positioned therebetween is opened to atmospheric pressure, and the vibration of the air bag on the central side is prevented from propagating to the air bag on the peripheral side.

摘要翻译： 测量装置包括外围一侧的气囊，中央侧的气囊和位于其间的气囊。 在血压测量期间，气囊整体地起作用，并且根据其内部压力的变化来测量血压。 在脉搏波测量期间，外周侧气囊的内压保持在收缩压以上，测量部位为血管。 中央侧的气囊的内部压力保持在接近血压值的压力，并且根据其内部压力的变化来测量脉搏波。 位于其间的气囊的内部压力打开到大气压力，并且防止中央侧的气囊的振动传播到周边的气囊。

公开(公告)号：US09022942B2

公开(公告)日：2015-05-05

申请号：US13471588

申请日：2012-05-15

申请人： David E. Quinn ,  Matt Kinsley ,  Tyson B. Whitaker ,  John D. Seller

发明人： David E. Quinn ,  Matt Kinsley ,  Tyson B. Whitaker ,  John D. Seller

IPC分类号： A61B5/02 ,  A61B5/022 ,  A61B5/021 ,  A61B5/0225 ,  A61B5/11 ,  A61B5/00

CPC分类号： A61B5/02225 ,  A61B5/02007 ,  A61B5/021 ,  A61B5/022 ,  A61B5/0225 ,  A61B5/1107 ,  A61B5/6824

摘要： Disclosed herein is a system for monitoring a patient that includes a cuff configured to inflate to at least partially occlude an artery of the patient and a cuff controller configured to control inflation and deflation of the cuff. The system also includes a sensor configured to receive a signal associated with the at least partially occluded artery and generate an output signal based on the received signal. Also included is a signal analysis module configured to receive the output signal and determine a first hemodynamic parameter based on a first set of data obtained during inflation of the cuff and a second set of data obtained during deflation of the cuff.

摘要翻译： 本文公开了一种用于监测患者的系统，该系统包括被配置为膨胀以至少部分地闭塞患者的动脉的袖带和被配置为控制袖带的充气和放气的袖带控制器。 该系统还包括被配置为接收与至少部分闭塞的动脉相关联的信号并且基于接收到的信号产生输出信号的传感器。 还包括信号分析模块，其被配置为接收输出信号并且基于在袖带充气期间获得的第一组数据和在袖带放气期间获得的第二组数据来确定第一血液动力学参数。

公开(公告)号：US08986231B2

公开(公告)日：2015-03-24

申请号：US13048837

申请日：2011-03-15

申请人： Michael Gertner ,  David Perozek ,  Arash Sabet ,  Jimin Zhang

发明人： Michael Gertner ,  David Perozek ,  Arash Sabet ,  Jimin Zhang

IPC分类号： A61H1/00 ,  A61B8/08 ,  A61B5/00 ,  A61N7/00 ,  A61B5/0225 ,  A61B5/055 ,  A61B6/03 ,  A61B19/00 ,  A61N7/02 ,  A61B18/00

CPC分类号： A61B8/08 ,  A61B5/0225 ,  A61B5/055 ,  A61B5/4035 ,  A61B5/4041 ,  A61B5/4047 ,  A61B5/4052 ,  A61B5/412 ,  A61B5/4504 ,  A61B5/489 ,  A61B5/4893 ,  A61B6/032 ,  A61B8/0891 ,  A61B8/4245 ,  A61B8/485 ,  A61B8/488 ,  A61B90/37 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00511 ,  A61B2090/374 ,  A61B2090/3762 ,  A61B2090/378 ,  A61N7/00 ,  A61N7/02 ,  A61N2007/0026 ,  A61N2007/003

摘要： A system for treatment of an autonomic nervous system of a patient includes a focused ultrasound energy source for placement outside the patient, wherein the focused ultrasound energy source is configured to deliver ultrasound energy towards a blood vessel with a surrounding nerve that is a part of the autonomic nervous system inside the patient, and wherein the focused ultrasound energy source is configured to deliver the ultrasound energy based on a position of an indwelling vascular catheter.

摘要翻译： 用于治疗患者的自主神经系统的系统包括用于放置在患者外部的聚焦超声能量源，其中聚焦的超声能量被配置为向具有周围神经的血管传送超声能量，周围神经是部分 患者内部的自主神经系统，并且其中聚焦的超声能量源被配置为基于留置血管导管的位置输送超声能量。

公开(公告)号：US08951205B2

公开(公告)日：2015-02-10

申请号：US13749515

申请日：2013-01-24

申请人： Cardiac Pacemakers, Inc.

发明人： Abhilash Patangay ,  Krzysztof Z. Siejko

IPC分类号： A61B5/0225 ,  A61B5/0205 ,  A61B5/0432 ,  A61B7/04

CPC分类号： A61B7/04 ,  A61B5/02028 ,  A61B5/0205 ,  A61B5/0432 ,  A61B5/076 ,  A61B5/1116 ,  A61B5/4836 ,  A61B5/6869 ,  A61B5/7282 ,  A61B5/746 ,  A61B7/00 ,  A61B7/023 ,  A61N1/36514 ,  A61N1/36528

摘要： A cardiac rhythm management system provides for ambulatory monitoring of hemodynamic performance based on quantitative measurements of heart sound related parameters for diagnostic and therapeutic purposes. Monitoring of such heart sound related parameters allows the cardiac rhythm management system to determine a need for delivering a therapy and/or therapy parameter adjustments based on conditions of a heart. This monitoring also allows a physician to observe or assess the hemodynamic performance for diagnosing and making therapeutic decisions. Because the conditions of the heart may fluctuate and may deteriorate significantly between physician visits, the ambulatory monitoring, performed on a continuous or periodic basis, ensures a prompt response by the cardiac rhythm management system that may save a life, prevent hospitalization, or prevent further deterioration of the heart.

摘要翻译： 心律管理系统基于用于诊断和治疗目的的心音相关参数的定量测量，提供对血液动力学性能的动态监测。 监测这种心脏声音相关参数允许心律管理系统基于心脏的情况来确定递送治疗和/或治疗参数调整的需要。 该监测还允许医师观察或评估用于诊断和作出治疗决定的血液动力学性能。 由于心脏的状况可能波动，并且可能在医师访问之间显着恶化，所以在连续或周期性的基础上进行的动态监测可确保心律管理系统能够节省生命，预防住院或进一步防止心律失常的迅速反应 心脏恶化

公开(公告)号：US20150005649A1

公开(公告)日：2015-01-01

申请号：US14372404

申请日：2012-10-29

申请人： OMRON HEALTHCARE CO., LTD.

发明人： Yoshihisa Miwa ,  Takeyasu Hashimoto

IPC分类号： A61B5/0225 ,  A61B5/0235 ,  A61B5/021 ,  A61B5/022

CPC分类号： A61B5/0225 ,  A61B5/02108 ,  A61B5/022 ,  A61B5/02225 ,  A61B5/02233 ,  A61B5/0235

摘要： A blood pressure meter includes an air bladder for attachment to a measurement area, a pressure sensor, a pump a valve, drive circuits, a CPU connected to the pressure sensor and the drive circuits, for controlling the adjustment of the internal pressure of the air bladder and calculating a blood pressure value based on a change in the internal pressure resulting from the adjustment, and a holding portion, into and from which air can flow from and to the air bladder, that has a lower volume than the air bladder. The air can flow from the holding portion into the air bladder in the case where a predetermined pressure is applied to the holding portion. The CPU starts the adjustment of the internal pressure in the case where a change in the internal pressure prior to the start of the adjustment of the internal pressure is a predefined change.

摘要翻译： 血压计包括用于附接到测量区域的气囊，压力传感器，泵阀，驱动电路，连接到压力传感器的CPU和驱动电路，用于控制空气的内部压力的调节 膀胱，并且基于由调节产生的内部压力的变化计算血压值，以及保持部分，空气可以从空气囊流过空气囊并从空气囊流过空气囊。 在预定压力被施加到保持部分的情况下，空气可以从保持部分流入气囊。 在内部压力调节开始之前的内部压力变化为预定的变化的情况下，CPU开始内部压力的调整。

公开(公告)号：US08814800B2

公开(公告)日：2014-08-26

申请号：US12915496

申请日：2010-10-29

申请人： Jürgen Fortin ,  Rupert Grüllenberger

发明人： Jürgen Fortin ,  Rupert Grüllenberger

IPC分类号： A61B5/02 ,  A61B5/021 ,  A61B5/024 ,  A61B5/0225 ,  A61B5/022 ,  A61B5/025 ,  A61B5/00

CPC分类号： A61B5/0059 ,  A61B5/022 ,  A61B5/02241 ,  A61B5/7203

摘要： A system and method of enhancing a blood pressure signal is disclosed. The volume of an artery in a finger is measured by a photo-plesthysmographic (PPG) system, which produces a PPG signal. This PPG system is placed inside a cuff, and the cuff pressure is controlled by the PPG signal. The portion or component of the PPG signal having a frequency higher than a predefined threshold frequency is then modified or enhanced, such as by multiplying the high frequency component by a calibration factor. A blood pressure signal is then calculated using the cuff pressure and the modified PPG signal. A blood pressure contour curve may then be generated, and a variety of parameters may be calculated using the curve.

摘要翻译： 公开了增强血压信号的系统和方法。 通过用于产生PPG信号的光电吸收（PPG）系统来测量手指中的动脉的体积。 该PPG系统放置在袖口内，袖带压力由PPG信号控制。 然后，修改或增强具有高于预定阈值频率的频率的PPG信号的部分或部分，例如通过将高频分量乘以校准因子。 然后使用袖带压力和修改的PPG信号计算血压信号。 然后可以产生血压轮廓曲线，并且可以使用曲线计算各种参数。

公开(公告)号：US08798703B2

公开(公告)日：2014-08-05

申请号：US13226596

申请日：2011-09-07

申请人： Christian Huber ,  Rupert Grüllenberger ,  Jürgen Fortin

发明人： Christian Huber ,  Rupert Grüllenberger ,  Jürgen Fortin

IPC分类号： A61B5/00 ,  A61B5/02 ,  A61B5/022 ,  A61B5/0225

CPC分类号： A61B5/02241 ,  A61B5/02255 ,  A61B5/6826 ,  A61B5/6831 ,  A61B2560/0406 ,  A61B2560/0443 ,  A61B2562/164 ,  Y10T29/49826

摘要： A sensor system for continuous non-invasive arterial blood pressure (CNAP) is provided. The CNAP-sensor comprises of a base portion and a detachable and disposable portion. The base portion is connected to a control system. The disposable portion is for attachment to a human body part. The CNAP-sensor system includes a photo-plethysmographic (PPG) system having at least one light source, at least one light detector, electrical supplies, light coupling systems, one or more connectors, and a cuff including air supplies.

摘要翻译： 提供了一种用于连续非侵入性动脉血压（CNAP）的传感器系统。 CNAP传感器包括基部和可拆卸和一次性部分。 基座部分连接到控制系统。 一次性部分用于附接到人体部分。 CNAP传感器系统包括具有至少一个光源，至少一个光检测器，电源，光耦合系统，一个或多个连接器和包括空气供应的袖带的光体积描记术（PPG）系统。

公开(公告)号：US20140194755A1

公开(公告)日：2014-07-10

申请号：US14238395

申请日：2012-08-30

申请人： Kazuhiro Ide ,  Masato Izumikawa

发明人： Kazuhiro Ide ,  Masato Izumikawa

IPC分类号： A61B5/0225

CPC分类号： A61B5/0225 ,  A61B5/02007 ,  A61B5/02116 ,  A61B5/02225 ,  A61B5/6843 ,  A61B5/7275 ,  A61B5/742 ,  G06F19/00

摘要： The circulatory dynamics measurement apparatus comprises: a blood pressure-computing unit, which calculates the maximum blood pressure value (SYS); a vascular sclerosis-computing unit, which calculates the vascular sclerosis index (VSI); and a display unit for displaying a graph having a horizontal axis that represents the maximum blood pressure and a vertical axis that represents the vascular sclerosis index. The display unit displays the position determined by the calculated maximum blood pressure value and the calculated vascular sclerosis index in the plotting area of the graph.

摘要翻译： 循环动力学测量装置包括：计算最大血压值（SYS）的血压计算单元; 计算血管硬化指数（VSI）的血管硬化计算单元; 以及显示单元，用于显示具有表示最大血压的水平轴的图形和表示血管硬化指数的纵轴。 显示单元在图表的绘制区域中显示由计算的最大血压值和计算的血管硬化指数确定的位置。