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    NANOTUBE BASED TRANSISTOR STRUCTURE, METHOD OF FABRICATION AND USES THEREOF
    751.
    发明申请
    NANOTUBE BASED TRANSISTOR STRUCTURE, METHOD OF FABRICATION AND USES THEREOF 审中-公开
    基于纳米管的晶体管结构，其制造方法及其用途

    公开(公告)号：US20160285018A1

    公开(公告)日：2016-09-29

    申请号：US15034186

    申请日：2014-11-06

    Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD.

    Inventor： Illani SHAHAL ,  Sharon PECKER ,  Avishal BENYAMINI ,  Jonah WAISMANN ,  Assaf HAMO ,  Maayan HONIG

    IPC: H01L51/05 ,  H01L51/10 ,  G01Q70/08 ,  H01L51/00

    CPC classification number: H01L51/0558 ,  C01B32/16 ,  H01L22/14 ,  H01L29/0673 ,  H01L29/1029 ,  H01L29/66045 ,  H01L29/772 ,  H01L51/0012 ,  H01L51/0024 ,  H01L51/003 ,  H01L51/0031 ,  H01L51/0045 ,  H01L51/0048 ,  H01L51/0508 ,  H01L51/105

    Abstract: A method for use in construction of an electronic device and a transistor structure are presented. The method comprising: providing one or more nanotubes grown on a surface of a first substrate; providing a desired electrode arrangement fabricated on a surface of a second substrate. The electrode arrangement comprises at least two elevated source and drain electrodes and one or more gate electrodes located in between said elevated source and drain electrodes. The method also comprises bringing the electrode arrangement on the second substrate to close proximity with the first substrate such that surfaces of the first and second substrates face each other; scanning said first substrate with said electrode arrangement and determining contact of electrodes of the electrode arrangement with a nanotube located on the first substrate; and detaching said nanotube from the first substrate to provide a transistor structure comprising an isolated nanotube between the source and drain electrodes.

    Abstract translation: 提出了一种用于构造电子器件和晶体管结构的方法。 该方法包括：提供在第一基底的表面上生长的一个或多个纳米管; 提供制造在第二基板的表面上的期望的电极布置。 电极布置包括至少两个升高的源极和漏极以及位于所述升高的源极和漏极之间的一个或多个栅电极。 所述方法还包括使所述第二基板上的所述电极布置与所述第一基板靠近，使得所述第一和第二基板的表面彼此面对; 用所述电极装置扫描所述第一衬底，并且确定所述电极装置的电极与位于所述第一衬底上的纳米管的接触; 以及从所述第一衬底分离所述纳米管，以提供在所述源极和漏极之间包括隔离纳米管的晶体管结构。

    METHOD AND APPARATUS FOR PREDICTING RESPONSE TO FOOD
    753.
    发明申请
    METHOD AND APPARATUS FOR PREDICTING RESPONSE TO FOOD 审中-公开
    用于预测食物反应的方法和装置

    公开(公告)号：US20160232311A1

    公开(公告)日：2016-08-11

    申请号：US15022643

    申请日：2015-04-28

    Applicant: YEDA RESEARCH AND DEVELOPMENT CO., LTD.

    Inventor： Eran SEGAL ,  Eran ELINAV

    IPC: G06F19/00 ,  G06N99/00

    CPC classification number: G16H50/20 ,  G06F19/3475 ,  G06N20/00 ,  G16H50/70 ,  Y02A90/26

    Abstract: Method of predicting a response of a subject to food is disclosed. The method comprises: selecting a food to which a response of the subject is unknown; accessing a first database having data describing the subject but not a response of the subject to the selected food; accessing a second database having data pertaining to responses of other subjects to foods, the responses of the other subjects including responses of at least one other subject to the selected food or a food similar to said selected food; and analyzing the databases based on the selected food to estimate the response of the subject to the selected food.

    Abstract translation: 公开了预测受试者对食物的反应的方法。 该方法包括：选择对象的反应未知的食物; 访问具有描述所述对象的数据的第一数据库，而不是所述对象对所选食物的响应; 访问具有与其他受试者对食物有关的数据的第二数据库，其他对象的反应包括至少一个其他受试者对所选食物的反应或与所述选定食物相似的食物; 以及基于所选择的食物分析数据库以估计受试者对所选食物的反应。

    METHOD AND ELECTRONIC NOSE FOR COMPARING ODORS
    755.
    发明申请
    METHOD AND ELECTRONIC NOSE FOR COMPARING ODORS 审中-公开
    用于比较气味的方法和电子信息

    公开(公告)号：US20160216244A1

    公开(公告)日：2016-07-28

    申请号：US14917290

    申请日：2014-09-11

    Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD.

    Inventor： Noam SOBEL ,  Kobi SNITZ ,  Adi YABLONKA-BARAK ,  Tali WEISS ,  Idan FRUMIN ,  Aharon RAVIA

    IPC: G01N33/00

    CPC classification number: G01N33/0062 ,  G01N33/0031 ,  G01N2033/0068

    Abstract: A method for comparing odors comprises: sampling odor sources and detecting primary odorants, then for each odor source, storing each of the sampled odor sources in respective primary vectors of odor descriptors that describe the primary odorants. For each source a source vector is then constructed by summing the primary vectors of the respectively detected primary odorants. Comparison between the odors is achieved by determining an angle between the source vectors, which may then be output. The method may be used in electronic noses and like equipment.

    Abstract translation: 用于比较气味的方法包括：取样气味源和检测主要气味剂，然后对于每个气味源，将每个采样的气味源存储在描述主要气味剂的气味描述符的相应主要载体中。 对于每个源，然后通过对分别检测到的主要气味剂的主要载体求和来构建源向量。 通过确定源向量之间的角度来实现气味之间的比较，然后可以输出它们之间的角度。 该方法可用于电子鼻和类似设备中。

    GLYCOGEN SYNTHASE KINASE-3 INHIBITORS
    756.
    发明申请
    GLYCOGEN SYNTHASE KINASE-3 INHIBITORS 有权

    公开(公告)号：US20160200763A1

    公开(公告)日：2016-07-14

    申请号：US14392205

    申请日：2014-06-24

    Applicant: RAMOT AT TEL-AVIV UNIVERSITY LTD. ,  YEDA RESEARCH AND DEVELOPMENT CO. LTD.

    Inventor： Hagit ELDAR-FINKELMAN ,  Miriam EISENSTEIN ,  Avital LICHT-MURAVA

    IPC: C07K7/06 ,  C40B30/02 ,  G06F19/16 ,  C07K7/08 ,  A61K47/48

    CPC classification number: C07K7/06 ,  A61K38/00 ,  A61K38/08 ,  A61K38/10 ,  C07K7/08 ,  C40B30/02 ,  G06F19/16 ,  Y02A50/401 ,  Y02A50/409 ,  Y02A50/411 ,  Y02A50/414 ,  Y02A50/415 ,  Y02A50/419 ,  Y02A50/422 ,  Y02A50/423 ,  Y02A50/491

    Abstract: Novel peptide inhibitors of GSK-3, compositions containing same and uses thereof are disclosed. The novel peptide inhibitors are converted to inhibitors of GSK-3 upon interacting with the enzyme's catalytic site and hence act as disease-selective inhibitors for treating conditions associated with increased activity and/or expression of GSK-3. Each of the disclosed peptides is independently of no more than 15 amino acid residues, and has an amino acid sequence which comprises a ZX1X2X3Z(p) recognition motif of GSK-3, wherein Z(p) is a phosphorylated serine or threonine residue; Z is a phosphorylatable serine or threonine residue, and each of X1, X2 and X3 is independently any amino acid, as defined in the specification. Further disclosed are methods of identifying a putative substrate-competitive peptide inhibitor of GSK-3 which are effected by computational modeling and screening.

    Abstract translation: 公开了GSK-3的新型肽抑制剂，含有其的组合物及其用途。 当与酶的催化位点相互作用时，新型肽抑制剂被转化为GSK-3的抑制剂，因此作为用于治疗与增加的GSK-3的活性和/或表达相关的病症的疾病选择性抑制剂。 所公开的肽各自独立地不超过15个氨基酸残基，并且具有包含GSK-3的ZX1X2X3Z（p）识别基序的氨基酸序列，其中Z（p）是磷酸化丝氨酸或苏氨酸残基; Z是可磷酸化的丝氨酸或苏氨酸残基，X1，X2和X3各自独立地是任何氨基酸，如说明书中所定义的。 进一步公开的是鉴定GSK-3的推定的底物竞争性肽抑制剂的方法，其通过计算建模和筛选来实现。

    Human Monocyte Sub-Population for Treatment of Eye Diseases and Disorders
    757.
    发明申请
    Human Monocyte Sub-Population for Treatment of Eye Diseases and Disorders 审中-公开
    人类单核细胞亚群用于治疗眼部疾病和疾病

    公开(公告)号：US20160166612A1

    公开(公告)日：2016-06-16

    申请号：US14898732

    申请日：2014-05-22

    Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD

    Inventor： Michal EISENBACH-SCHWARTZ ,  Ester YOLES ,  Inbal BENHAR BAR-ON

    IPC: A61K35/15 ,  A61K9/00

    CPC classification number: A61K35/15 ,  A61K9/0048 ,  A61K35/17 ,  A61K39/0008 ,  A61K2035/122 ,  A61K2039/5154 ,  C12N5/0645

    Abstract: A monocyte subpopulation having a low relative amount, or substantially devoid, of CD3+ cells, CD19+ cells, CD56+ cells and optionally CD16+ cells is provided, wherein the monocyte subpopulation is for use in inhibition of neuronal degeneration, protection of neurons from glutamate toxicity or promotion of nerve regeneration in the retina or optic nerve, wherein the retina or optic nerve is damaged by a disease, disorder or condition of the eye, or for treatment of an inflammatory disease, disorder or condition of the eye.

    Abstract translation: 提供了具有低相对量或基本上不含CD3 +细胞，CD19 +细胞，CD56 +细胞和任选的CD16 +细胞的单核细胞亚群，其中所述单核细胞亚群用于抑制神经元变性，保护神经元免于谷氨酸毒性或促进 在视网膜或视神经中的神经再生，其中视网膜或视神经被眼睛的疾病，病症或状况损伤，或用于治疗眼睛的炎性疾病，病症或病症。

    Antibody combinations and use of same for treating cancer
    758.
    发明授权
    Antibody combinations and use of same for treating cancer 有权
    抗体组合及其用途用于治疗癌症

    公开(公告)号：US09358288B2

    公开(公告)日：2016-06-07

    申请号：US14536754

    申请日：2014-11-10

    Applicant: Yeda Research and Development Co. Ltd.

    Inventor： Michael Sela ,  Yosef Yarden ,  Bilha Schechter ,  Tsipi Ben-Kasus

    IPC: C07K16/32 ,  A61K39/395 ,  A61K39/00

    CPC classification number: A61K39/3955 ,  A61K2039/505 ,  A61K2039/507 ,  C07K16/32 ,  C07K2317/565

    Abstract: A method of identifying a combination of antibodies with a combined improved anti-tumor activity is provided. The method comprising: (a) identifying binding epitopes of anti ErbB-2 antibodies; and (b) selecting a combination of at least two antibodies of the anti ErbB-2 antibodies exhibiting binding to different epitopes on the ErbB-2, at least one of the different epitopes being localized to a dimerization site of the ErbB-2, the combination of antibodies being with the combined improved anti-tumor activity. Also provided are novel antibody combinations uncovered according to the present teachings.

    Abstract translation: 提供了鉴定具有组合改善的抗肿瘤活性的抗体组合的方法。 该方法包括：（a）鉴定抗ErbB-2抗体的结合表位; 和（b）选择表现出与ErbB-2上不同表位结合的抗ErbB-2抗体的至少两种抗体的组合，至少一种不同表位位于ErbB-2的二聚位点， 抗体与组合的改善的抗肿瘤活性的组合。 还提供了根据本发明揭示的新型抗体组合。

    PLANT WITH ALTERED CONTENT OF STEROIDAL GLYCOALKALOIDS
    759.
    发明申请
    PLANT WITH ALTERED CONTENT OF STEROIDAL GLYCOALKALOIDS 审中-公开
    植物具有改变的外源性甘草酸的含量

    公开(公告)号：US20160122775A1

    公开(公告)日：2016-05-05

    申请号：US14895059

    申请日：2014-06-02

    Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD.

    Inventor： Asaph AHARONI ,  Maxim ITKIN

    IPC: C12N15/82

    CPC classification number: C12N15/8218 ,  C12N15/8243 ,  C12N15/8247

    Abstract: The present invention relates to genetically modified plants by key genes involved in the biosynthesis of steroidal alkaloids. These plants have altered content of steroidal (glyco)alkaloids. Solanaceous crop plants with reduced content of antinutritional steroidal glycoalkaloids are provided.

    Abstract translation: 本发明涉及通过涉及甾体生物碱生物合成的关键基因的遗传修饰植物。 这些植物改变了类固醇（glyco）生物碱的含量。 提供了抗营养型甾体生物碱含量降低的茄科作物。

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