-
公开(公告)号：US20180044743A1
公开(公告)日：2018-02-15
申请号：US15673973
申请日：2017-08-10
Applicant: THE CURATORS OF THE UNIVERSITY OF MISSOURI , THE UNIVERSITY OF BRITISH COLUMBIA , The Board of Regents of the University of Oklahoma , INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY
Inventor： MOJGAN PADASH BARMCHI , BING ZHANG , VANESSA J. AULD , LAWRENCE BANKS , MARY GILBERT
IPC: C12Q1/70 , G01N33/574 , C07K14/705 , C12Q1/68
CPC classification number: C12Q1/708 , A01K67/0339 , A01K2217/05 , A01K2217/052 , A01K2217/15 , A01K2227/706 , A01K2267/0393 , C07K14/005 , C07K14/705 , C07K14/82 , C12N9/93 , C12N15/00 , C12N2710/20022 , C12Q1/6806 , C12Q1/686 , C12Q1/6886 , C12Q2600/106 , C12Q2600/112 , C12Q2600/136 , G01N33/5085 , G01N33/574 , G01N2333/025 , G01N2333/43573
Abstract: Disclosed is a transgenic Drosophila model of human papillomavirus-mediated cancer. Also disclosed is a method for screening a candidate therapeutic for Human papillomavirus-induced cell transformation and a method for screening a candidate therapeutic for Human papillomavirus-induced cell transformation.
-
公开(公告)号：US09885072B2
公开(公告)日：2018-02-06
申请号：US15467683
申请日：2017-03-23
Inventor： Paul L. DeAngelis , Phillip Pummill , Regina C. Visser
CPC classification number: C12P19/26 , A61K8/735 , A61K31/726 , A61L27/20 , C12N9/1051 , C12P19/18 , C12Y204/01 , C08L5/10
Abstract: High molecular weight heparosan polymers are described, as are methods of producing and using the high molecular weight heparosan polymers.
-
公开(公告)号：US09839690B2
公开(公告)日：2017-12-12
申请号：US15187227
申请日：2016-06-20
Inventor： Youngjae You , Moses Bio , Abu Gafar Hossion , Gregory Nkepang
CPC classification number: A61K41/0042 , A61K31/09 , A61K31/4745 , A61K47/546 , A61K49/0006 , A61N5/062 , A61N5/10 , A61N2005/0659 , A61N2005/0662
Abstract: Activatable compositions that include at least one functional moiety and at least one cleavable linker directly or indirectly linked to the at least one functional moiety are disclosed. The at least one functional moiety is inactive when linked to the linker and activated upon cleavage of the linker. Methods of production and use of the activatable composition are also disclosed.
-
74.发明申请公开(公告)号：US20170252454A1
公开(公告)日：2017-09-07
申请号：US15597824
申请日：2017-05-17
Inventor： Paul L. DeAngelis
IPC: A61K47/48
CPC classification number: A61K47/61
Abstract: Compositions, methods, and systems are disclosed for the development and use of heparosan as a therapeutic modifying agent or vehicle which can modulate drug cargo pharmacokinetics and behavior within a mammalian patient.
-
公开(公告)号：US20170236447A1
公开(公告)日：2017-08-17
申请号：US15503271
申请日：2015-08-13
Inventor： Jonathan Christian Stalling
Abstract: The present disclosure provides methods, tools, kits and electronic systems for transcribing non-Chinese language sounds into sound-associated Chinese language characters. The methods, tools, kits and systems use language devices (dictionaries and blocks) based on sound-associated Chinese characters obtained by parsing standard Chinese characters sounds into consonant sounds and vowel sounds which have correspondence to certain standard phonetic graphemes. Sequences of the sound-associated Chinese characters provide existing Chinese phonemes which represent specific sound sequences and syllables in the non-Chinese language.
-
Patent Agency Ranking
公开(公告)号：US09735955B2
公开(公告)日：2017-08-15
申请号：US14329683
申请日：2014-07-11
Inventor： Pramode Verma , Bhagyashri Darunkar , Nikhil Punekar
CPC classification number: H04L9/0858 , H04B10/0795 , H04B10/25 , H04B10/2507 , H04B10/66 , H04L9/08 , H04L9/0852 , H04L9/12 , H04L2209/08 , H04L2209/34
Abstract: Systems and methods for sharing data between a first node and second node are disclosed. The methods may include sharing a first initialization vector between a first node and a second node using a multi-stage cryptography protocol. A first bit stream of first information may be passed from the first node to the second node using a single-stage cryptography protocol that encodes a message with the first initialization vector.
-
公开(公告)号：US09629914B2
公开(公告)日：2017-04-25
申请号：US14060077
申请日：2013-10-22
Inventor： Paul L. DeAngelis
CPC classification number: C08B37/0075 , A61K9/0024 , A61K9/06 , A61K31/726 , A61K47/02 , A61K47/36 , A61L31/10 , A61L2420/02 , C07H5/04
Abstract: Biomaterial compositions that include an isolated heparosan polymer are disclosed, as well as kits containing such biomaterial compositions and methods of producing and using such biomaterial compositions.
-
78.发明申请Substrates and Inhibitors of Antiplasmin Cleaving Enzyme and Fibroblast Activation Protein and Methods of Use 审中-公开抗肿瘤酶和成纤维细胞活化蛋白的底物和抑制剂及其使用方法公开(公告)号：US20170066800A1
公开(公告)日：2017-03-09
申请号：US15357435
申请日：2016-11-21
Inventor： Patrick A. McKee , Kenneth W. Jackson , Kyung N. Lee , Victoria J. Christiansen
CPC classification number: C07K5/06026 , A61K38/00 , C07K5/02 , C07K5/021 , C07K5/081 , C07K5/1019 , C07K7/02 , C07K14/8121
Abstract: The presently disclosed inventive concept(s) include inhibitors of antiplasmin cleaving enzyme (APCE) and fibroblast activation protein alpha (FAP) which can be used in various therapies related to disorders of fibrin and α2-antiplasmin and abnormal cell proliferation. The presently disclosed inventive concept(s) also include substrates of APCE and FAP, which may be used, for example, in screening methods for identifying such inhibitors. The presently disclosed inventive concept(s) further include, but are not limited to, methods of treating or inhibiting atherosclerosis and thrombus disorders by altering the ratios of types of plasma α2-antiplasmin and to methods of treating conditions involving abnormal cell proliferation such as cancers.
Abstract translation: 目前公开的发明概念包括抗纤溶酶切割酶（APCE）和成纤维细胞活化蛋白α（FAP）的抑制剂，其可用于与纤维蛋白和α2-抗血纤维蛋白异常和异常细胞增殖相关的各种疗法。 目前公开的发明概念还包括APCE和FAP的底物，其可以用于例如用于鉴定这种抑制剂的筛选方法。 目前公开的发明构思还包括但不限于通过改变血浆α2-抗纤溶酶类型的比例来治疗或抑制动脉粥样硬化和血栓紊乱的方法以及治疗涉及异常细胞增殖的病症例如癌症的方法 。
-
79.发明申请Compositions Containing Very Long Chain Saturated Fatty Acids and Methods of Use 审中-公开包含非常长链饱和脂肪酸的组合物和使用方法公开(公告)号：US20170014365A1
公开(公告)日：2017-01-19
申请号：US15210469
申请日：2016-07-14
Inventor： Robert Eugene Anderson , Martin-Paul Agbaga , Richard S. Brush , Blake Hopiavuori
CPC classification number: A23L33/12 , A61K31/202
Abstract: A fatty acid composition comprising at least one purified very long chain saturated fatty acid (VLC-SFA) having a chain length in a range of from about 28 carbons to about 40 carbons which is conjugated to a carrier molecule, forming a VLC-SFA-carrier conjugate. Nutritional supplements containing the fatty acid compositions, and methods of producing and using the fatty acid compositions, are also disclosed.
Abstract translation: 脂肪酸组合物，其包含与载体分子缀合的具有约28个碳至约40个碳的链长度的至少一种纯化的长链饱和脂肪酸（VLC-SFA），形成VLC-SFA- 载体缀合物。 还公开了含有脂肪酸组合物的营养补充剂，以及生产和使用脂肪酸组合物的方法。
-
公开(公告)号：US20160340302A1
公开(公告)日：2016-11-24
申请号：US15107226
申请日：2014-12-22
Inventor： Graciela ARHANCET , Scott LONG , Xiaojun WANG , Richard Vonder EMBSE , Brian GRADY , Jeff HARWELL , Guangzhe YU
CPC classification number: C07C317/46 , A61K8/46 , A61Q19/00 , C08G75/14 , C08G75/18 , C11D1/008 , C11D1/12 , C11D1/29 , C11D1/755 , C11D3/22 , C11D3/3715 , C11D3/3719 , C11D11/0017
Abstract: The present invention provides sulfur- or selenium-containing compounds comprising hydrophobic moieties and ethoxylated ester or ethoxylated amide moieties such that the compounds have surfactant properties. Also provided are methods for using the disclosed compounds or mixtures thereof in a variety of applications.
Abstract translation: 本发明提供包含疏水部分和乙氧基化酯或乙氧基化酰胺部分的含硫或硒的化合物，使得化合物具有表面活性剂性质。 还提供了在各种应用中使用所公开的化合物或其混合物的方法。
-
-
-
-
-
-
-
-
-
Search Results
492
records
(took 0.044 seconds)
