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公开(公告)号:US10022509B2
公开(公告)日:2018-07-17
申请号:US15269102
申请日:2016-09-19
发明人: Declan Walsh , Derek Fenlon , Simon Kaar , Jan Geert Hazenberg , Daniel Buck , Paul Clancy , Robert Charles Uschold , Jeffrey A. Karg
摘要: A dose counter for an inhaler, the dose counter having a display tape arranged to be incrementally driven from a tape stock bobbin onto an incremental tape take-up drive shaft, the bobbin having an internal bore supported by and for rotation about a support shaft, at least one of the bore and support shaft having a protrusion which is resiliently biased into frictional engagement with the other of the bore and support shaft with longitudinally extending mutual frictional interaction.
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公开(公告)号:US20180140788A1
公开(公告)日:2018-05-24
申请号:US15704444
申请日:2017-09-14
发明人: Enrique Calderon Oliveras , Daniel Buck , Erica Jamie Kantor , Ross William Weir , James Roche , Steven David Gardner , Robert Owen Kivlin
CPC分类号: A61M15/0023 , A61B5/4833 , A61M15/0021 , A61M15/0025 , A61M15/0065 , A61M15/0086 , A61M15/009 , A61M15/0096 , A61M2202/064 , A61M2205/3569 , A61M2205/50 , A61M2205/502 , A61M2205/8206 , A61M2205/8212
摘要: The introduction of electronics into a drug delivery device may introduce certain technical challenges, such as durability, electro-mechanical integration, and drug delivery performance. The present disclosure provides solutions for inclusion of an electronics module with an inhaler. For example, heat stakes may be used to secure a printed circuit board (PCB) to an electronics module's housing. Also for example, a slider may be used to transfer vertical movement of an inhaler's yoke to an electronics module's switch. Also for example, certain seals may be used when interfacing the electronics module to other portions of the device's housing to achieve a desired performance.
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公开(公告)号:US20180056014A1
公开(公告)日:2018-03-01
申请号:US15804735
申请日:2017-11-06
发明人: Declan Walsh , Derek Fenlon , Simon Kaar , Jan Geert Hazenberg , Daniel Buck , Paul Clancy , Robert Charles Uschold , Jeffrey A. Karg
摘要: An inhaler includes a main body having a canister housing, a medicament canister retained in a central outlet port of the canister housing, and a dose counter having an actuation member for operation by movement of the medicament canister. The canister housing has an inner wall, and a first inner wall canister support formation extending inwardly from a main surface of the inner wall. The canister housing has a longitudinal axis X which passes through the center of the central outlet port. The first inner wall canister support formation, the actuation member, and the central outlet port lie in a common plane coincident with the longitudinal axis X such that the first inner wall canister support formation protects against unwanted actuation of the dose counter by reducing rocking of the medicament canister relative to the main body of the inhaler.
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公开(公告)号:US20170340844A1
公开(公告)日:2017-11-30
申请号:US15681126
申请日:2017-08-18
IPC分类号: A61M15/00
摘要: A compliance monitoring module for a breath-actuated inhaler comprising: a miniature pressure sensor, a sensor port of said sensor being pneumatically coupled to a flow channel through which a user can inhale; a processor configured to: receive a signal originating from a dosing mechanism of the inhaler indicating that medication has been released; receive data from a sensing element of the sensor; and based on said signal from said dosing mechanism and said data from said sensing element, make a determination that inhalation of a breath containing medication through said flow channel complies with one or more predetermined requirements for successful dosing; and a transmitter configured to, responsive to said determination, issue a dosing report.
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公开(公告)号:US20170290527A1
公开(公告)日:2017-10-12
申请号:US15507386
申请日:2015-08-28
CPC分类号: A61B5/087 , A61B5/097 , A61B5/4833 , A61B2562/028 , A61B2562/0285 , A61M15/00 , A61M15/009 , A61M15/0096 , A61M16/0051 , A61M16/0063 , A61M16/021 , A61M2016/0027 , A61M2209/088
摘要: A compliance monitoring module for an inhaler comprising: a miniature pressure sensor, a sensor port of said sensor being configured to be pneumatically coupled to a flow channel of said inhaler through which a user can inhale; a processor configured to: receive data from a sensing element of the pressure sensor; receive data from a mode sensor configured to detect when the inhaler changes from an inactive mode to an active mode; and based on said data from said pressure sensor sensing element and said data from said mode sensor, compile a compliance report; and a transmitter configured to issue said compliance report.
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公开(公告)号:US09782550B2
公开(公告)日:2017-10-10
申请号:US15155400
申请日:2016-05-16
IPC分类号: A61M15/00
CPC分类号: A61M15/0065 , A61M15/00 , A61M15/0026 , A61M15/0071 , A61M15/008 , A61M15/009 , A61M15/0091 , A61M2205/3331 , A61M2205/3576 , A61M2205/3584 , A61M2205/50 , A61M2205/58 , A61M2205/583 , A61M2205/584 , A61M2205/587 , A61M2209/088
摘要: A compliance monitoring module for a breath-actuated inhaler comprising: a miniature pressure sensor, a sensor port of said sensor being pneumatically coupled to a flow channel through which a user can inhale; a processor configured to: receive a signal originating from a dosing mechanism of the inhaler indicating that medication has been released; receive data from a sensing element of the sensor; and based on said signal from said dosing mechanism and said data from said sensing element, make a determination that inhalation of a breath containing medication through said flow channel complies with one or more predetermined requirements for successful dosing; and a transmitter configured to, responsive to said determination, issue a dosing report.
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公开(公告)号:US20170189630A1
公开(公告)日:2017-07-06
申请号:US15309538
申请日:2015-05-13
发明人: James Noel POWER , Simon KAAR , Andrew GIBBS
CPC分类号: A61M15/009 , A61M15/08 , B65D83/205 , B65D83/28 , B65D83/54
摘要: The present invention provides an aerosol device for delivering a pharmaceutical formulation by inhalation via the mouth to the lungs or to the nostril in metered doses comprising: a pressurised aerosol canister including a vial containing a pharmaceutical formulation comprising an active ingredient, a propellant and, optionally, a co-solvent, the aerosol canister further comprising a metering valve having a valve stem; and an actuator for the aerosol canister, the actuator including a delivery outlet and a stem block, the stem block having a receptacle into which the valve stem of the metering valve of the aerosol canister is received and axially located and being displaceable relative to the vial of the aerosol canister to actuate the metering valve of the aerosol canister, a sump extending below the receptacle, the stem block further defining a discharge orifice arranged to direct the pharmaceutical formulation through the delivery outlet, a transfer tunnel having an input opening and an output opening through which a dispensed dose of the pharmaceutical formulation is able to pass from the sump to the discharge orifice, and a land length defining the distance from between the input opening and output opening, wherein the input opening and the output opening have cross-sectional areas of from 0.002 to 0.8 mm2 and the cross-sectional area of the input opening is smaller than the cross-sectional area of the output opening, and wherein the land length is from 0.5 mm to 10 mm.
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公开(公告)号:US20160375208A1
公开(公告)日:2016-12-29
申请号:US15262818
申请日:2016-09-12
发明人: Declan Walsh , Derek Fenlon , Simon Kaar , Jan Geert Hazenberg , Daniel Buck , Paul Clancy , Robert Charles Uschold , Jeffrey A. Karg
IPC分类号: A61M15/00
摘要: A dose counter for an inhaler includes a counter display arranged to indicate dosage information, and a drive system arranged to move the counter display incrementally in a first direction from a first station to a second station in response to actuation input. A regulator is provided which is arranged to act upon the counter display at the first station to regulate motion of the counter display at the first station to incremental movements.
摘要翻译: 用于吸入器的剂量计数器包括布置成指示剂量信息的计数器显示器,以及驱动系统,其被布置成响应于致动输入而从第一站向第二站向第一方向递增地移动计数器显示。 提供了调节器,其被布置成作用在第一站处的计数器显示器上,以将第一站处的计数器显示器的运动调节为增量运动。
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公开(公告)号:US20240342404A1
公开(公告)日:2024-10-17
申请号:US18751627
申请日:2024-06-24
IPC分类号: A61M15/00 , A61B5/00 , A61B5/08 , A61K31/138 , A61M11/00 , C07K16/24 , C07K16/28 , C07K16/42 , G16H20/10 , G16H20/13 , G16H50/30 , G16H50/70
CPC分类号: A61M15/009 , A61B5/0826 , A61B5/4848 , A61B5/7275 , A61K31/138 , A61M15/0001 , A61M15/0025 , A61M15/003 , A61M15/008 , A61M15/0091 , C07K16/244 , C07K16/247 , C07K16/2866 , C07K16/4291 , G16H20/10 , G16H20/13 , G16H50/30 , G16H50/70 , A61M11/00 , A61M15/0026 , A61M2202/064 , A61M2205/05 , A61M2205/18 , A61M2205/3327 , A61M2205/3331 , A61M2205/3358 , A61M2205/3584 , A61M2205/502 , A61M2205/505 , A61M2205/52 , A61M2230/30 , A61M2230/40 , C07K2317/21 , C07K2317/24 , C07K2317/52
摘要: Provided is a system (10) for determining a probability of an asthma exacerbation in a subject. The system comprises an inhaler (100) for delivering a rescue medicament to the subject. The inhaler has a use-detection system (12B) configured to determine a rescue inhalation performed by the subject using the first inhaler. A sensor system (12A) is configured to measure a parameter relating to airflow during the rescue inhalation. The system further comprises a processor (14) configured to determine a number of the rescue inhalations during a first time period, and receive the parameter measured for at least some of the rescue inhalations. The processor determines, using a weighted model, the probability of the asthma exacerbation based on the number of rescue inhalations and the parameters. The model is weighted such that the number of rescue inhalations is more significant in the probability determination than the parameters.
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公开(公告)号:US11969544B2
公开(公告)日:2024-04-30
申请号:US16476390
申请日:2018-01-16
发明人: Daniel Buck
CPC分类号: A61M15/0008 , A61M15/0001 , A61M15/0086 , A61M15/0091 , A61M16/14 , G01N15/06 , A61M2202/064 , G01N2015/0046 , G01N2015/0693
摘要: The present disclosure describes an inhaler for the inhalation of powder medication. The inhaler has a body and at least one reservoir containing powder medication, the body having an air inlet and an outlet for the transmission to a patient of air entering the body through the air inlet and powder medication. The outlet has a total cross-sectional area for flow which is more than 80% of the total cross-sectional area of the air inlet.
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