Abstract:
The present invention is related to a method for improving a strain on the basis of in silico analysis, in which it compares the genomic information of a target strain for producing a useful substance to the genomic information of a strain overproducing the useful substance so as to primarily screen genes unnecessary for the overproduction of the useful substance, and then to secondarily screen genes to be deleted through performing simulation with metabolic flux analysis. According to the present invention, an improved strain can be effectively constructed by the metabolic and genetic engineering approach comprising comparatively analyzing the genomic information of a target strain for producing a useful substance and the genomic information of a strain producing a large amount of the useful substance to screen candidate genes and performing in silico simulation on the screened candidate genes to select a combination of genes to be deleted, which shows an improvement in the production of the useful substance. Accordingly, the time, effort and cost required for an actual wet test can be significantly reduced.
Abstract:
Provided are novel rumen bacterial mutants resulted from the disruption of a lactate dehydrogenase gene (ldhA) and a pyruvate formate-lyase gene (pfl) from rumen bacteria; a novel bacterial mutant (Mannheimia sp. LPK7) having disruptions of a ldhA, a pfl,a phosphotransacetylase gene (pta), and a acetate kinase gene (ackA); a novel bacterial mutant (Mannheimia sp. LPK4) having disruptions of a ldhA, a pfl, and a phosphoenolpyruvate carboxylase gene (ppc) involved in the immobilization of CO2 in a metabolic pathway of producing succinic acid; and a method for producing succinic acid, characterized by culture of the above mutants in anaerobic conditions. The bacterial mutants have the property of producing succinic acid at high concentration while producing little or no organic acids, as compared to the prior wild-type strains of producing various organic acids. Thus, the bacterial mutants are useful as strains for the industrial production of succinic acid.
Abstract:
The present invention relates to a composition containing genistein that accelerates the expression of the Carnitine Palmitoyl Transferase-1 (CPT-1) for improving or treating obesity. More particularly, the composition of the present invention comprises genistein that accelerates the expression of the CPT-1, an important enzyme for the lipolysis of fatty acid, and comprises carnitine that transports fatty acid into mitochondria and accelerates oxidation of fat in the oxidation process of fatty acid.
Abstract:
A backlight assembly, a method of driving the same, and a liquid crystal display (LCD) having the same includes a backlight assembly having first and second lamps, a power source for providing power, a sensor for outputting a sensing signal in accordance with the ambient luminance, a power controller for changing the level of the output power of the power source to provide the changed output power to the second lamp in response to the sensing signal, a feedback signal generator for generating a feedback signal as the power of the power source is supplied to the second lamp, and a power converter for providing the power of the power source to the first lamp or changing the level of the output power of the power source to provide the changed output power to the first lamp.
Abstract:
A pogo pin of a contact-type of semiconductor test device will not be oxidized and will not damage of a solder ball of a semiconductor package when the pogo pin is brought into contact with the solder ball. The pogo pin includes an electrical contact of a conductive rubber material, and a spring extending from the bottom of the electrical contact. The test device includes an array of the pogo pins, and a housing that supports the array of pogo pins. The housing may include detachable members between which the pogo pins are interposed such that the pogo pins can be individually replaced.
Abstract:
A display device testing system and a method for testing a display device using the same, which are capable of testing whether a display panel is defective or not according to a variation of the frame frequency and whether the driver module operates normally or not even at a voltage higher than a normal operation voltage. The display device testing system includes a display panel including a plurality of gate lines; a driver module including a gate driver unit for sequentially supplying a gate voltage to the plurality of gate lines in response to a test, vertical synchronization start signal; and a testing module for supplying a test vertical synchronization start signal to the driver module.
Abstract:
The present invention provides a plasma display apparatus comprising a second driver supplying a first bias signal with a voltage maintained at a first bias voltage in a reset period and an address period, a first sustain rising signal that gradually rises from the first bias voltage to a second bias voltage, and a second bias signal with a voltage maintained at the second bias voltage, to the second electrode.
Abstract:
The present invention relates to a composition for slimming, more particularly, to a slimming composition containing theanine and at least on selected from the group consisting of caffeine, genistein, L-carnitine and catechin. The composition of the present invention contains theanine and each of caffeine, genistein, L-carnitine or mixtures thereof, and has properties of decomposing fats, hydrolyzing lipid and removing cellulites.
Abstract:
A method is disclosed for calculating the optimal number of base transceiver stations (BTSs) in a wireless network and for determining a loading factor value therefor. The wireless network has a plurality of BTSs, each station providing communication service to mobile stations. As a loading factor value increases, the traffic decreases and the coverage area increases. The method calculates the number of BTSs in accordance with a decrease in traffic and the number of BTSs in accordance with an increase in the coverage area; determines a loading factor value which minimizes a difference between the two number of BTSs; and determines the optimal number of BTSs according to the determined loading factor value.
Abstract:
A method of fabricating a semiconductor light emitting device includes forming a first conductivity type semiconductor layer, forming an active layer by alternately forming a plurality of quantum well layers and a plurality of quantum barrier layers on the first conductivity type semiconductor layer, and forming a second conductivity type semiconductor layer on the active layer. The plurality of quantum barrier layers include at least one first quantum barrier layer adjacent to the first conductivity type semiconductor layer and at least one second quantum barrier layer adjacent to the second conductivity type semiconductor layer. The forming of the active layer includes allowing the at least one first quantum barrier layer to be grown at a first temperature and allowing the at least one second quantum barrier layer to be grown at a second temperature lower than the first temperature.