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85 条记录 (耗时 0.046 秒)

    LEADS FOR SELECTIVE SENSING AND VIRTUAL ELECTRODES
    73.
    发明申请
    LEADS FOR SELECTIVE SENSING AND VIRTUAL ELECTRODES 有权
    导电选择感应和虚拟电极

    公开(公告)号：US20100305675A1

    公开(公告)日：2010-12-02

    申请号：US12474645

    申请日：2009-05-29

    申请人： Timothy G. Laske ,  Gonzalo Martinez ,  Mark T. Marshall

    发明人： Timothy G. Laske ,  Gonzalo Martinez ,  Mark T. Marshall

    IPC分类号： A61N1/05

    CPC分类号： A61N1/0563 ,  A61B5/042 ,  A61N1/0534 ,  A61N1/0541 ,  A61N1/056

    摘要： Selective sensing implantable medical leads include pulsing and sensing portions and pulsing and not sensing portion. Leads and electrodes may be used in defibrillation and as integrated bipolar defibrillation electrodes. An entire electrode can pass charge while a valve metal or valve metal oxide portion of the electrode prevents the entire electrode from sensing, effectively rejecting unwanted signals. Differential conduction pathways, due to the valve metal and/or oxides thereof, cause the portions of the electrodes to conduct differently when used anodically and cathodically. Complex intracardiac electrical gradient can be formed along with a number of virtual electrodes within the tissue. Reentrant loops can thereby be pinned following defibrillation shock.

    摘要翻译： 选择性感测可植入医疗引线包括脉冲和感测部分以及脉冲和不感测部分。 引线和电极可用于除颤和作为集成的双极除颤电极。 整个电极可以通过电荷，同时电极的阀金属或阀金属氧化物部分防止整个电极感测，有效地排除不需要的信号。 由于阀门金属和/或其氧化物导致的差动传导路径导致当阳极和阴极使用时，电极的部分不同地传导。 可以与组织内的多个虚拟电极一起形成复杂的心内电梯度。 因此，除颤休克后可以固定可重入环。

    MULTI-LAYERED STENTS AND METHODS OF IMPLANTING
    75.
    发明申请
    MULTI-LAYERED STENTS AND METHODS OF IMPLANTING 审中-公开
    多层手术和植入方法

    公开(公告)号：US20100179641A1

    公开(公告)日：2010-07-15

    申请号：US12732329

    申请日：2010-03-26

    申请人： Timothy R. Ryan ,  Timothy G. Laske ,  Philipp Bonhoeffer ,  Silvia Schievano

    发明人： Timothy R. Ryan ,  Timothy G. Laske ,  Philipp Bonhoeffer ,  Silvia Schievano

    IPC分类号： A61F2/82

    CPC分类号： A61F2/852 ,  A61F2/2418 ,  A61F2/2475 ,  A61F2/90 ,  A61F2/915 ,  A61F2/958 ,  A61F2002/826 ,  A61F2002/828 ,  A61F2210/0076 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2220/0025 ,  A61F2220/0058 ,  A61F2230/0054 ,  A61F2240/001 ,  A61F2250/0015 ,  A61F2250/0018 ,  A61F2250/006 ,  Y10T29/49

    摘要： A method of percutaneously delivering a multi-layered stent assembly to a desired implantation location of a patient including the steps of radially compressing a multi-layered stent assembly to a compressed size for implantation in a patient, the multi-layered stent assembly including a first stent, a second stent coaxially positioned within at least a portion of a length of the first stent, and a valve, wherein the first stent comprises at least one different material property than the second stent. The method further includes delivering the multi-layered stent assembly to the desired implantation location of the patient using a delivery system and substantially simultaneously expanding the first stent and the second stent of the multi-layered stent assembly at the desired implantation location to a radially expanded size that is larger than the compressed size.

    摘要翻译： 一种将多层支架组件经皮递送到患者期望的植入位置的方法，包括将多层支架组件径向压缩至压缩尺寸以便植入患者的步骤，所述多层支架组件包括第一 支架，同轴地定位在第一支架的长度的至少一部分中的第二支架和阀，其中第一支架包括与第二支架相比的至少一种不同的材料特性。 该方法还包括使用递送系统将多层支架组件递送到患者的期望植入位置，并且将所述多层支架组件的第一支架和第二支架基本上同时地扩展到期望的植入位置，以径向扩张 尺寸大于压缩尺寸。

    Multi-layered stents and methods of implanting
    76.
    发明申请
    Multi-layered stents and methods of implanting 审中-公开
    多层支架和植入方法

    公开(公告)号：US20080262593A1

    公开(公告)日：2008-10-23

    申请号：US12070208

    申请日：2008-02-15

    申请人： Timothy R. Ryan ,  Timothy G. Laske ,  Philipp Bonhoeffer ,  Silvia Schievano

    发明人： Timothy R. Ryan ,  Timothy G. Laske ,  Philipp Bonhoeffer ,  Silvia Schievano

    IPC分类号： A61F2/84

    CPC分类号： A61F2/852 ,  A61F2/2418 ,  A61F2/2475 ,  A61F2/90 ,  A61F2/915 ,  A61F2/958 ,  A61F2002/826 ,  A61F2002/828 ,  A61F2210/0076 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2220/0025 ,  A61F2220/0058 ,  A61F2230/0054 ,  A61F2240/001 ,  A61F2250/0015 ,  A61F2250/0018 ,  A61F2250/006 ,  Y10T29/49

    摘要： A method of percutaneously delivering a multi-layered stent assembly to a desired implantation location of a patient including the steps of radially compressing a multi-layered stent assembly to a compressed size for implantation in a patient, the multi-layered stent assembly including a first stent, a second stent coaxially positioned within at least a portion of a length of the first stent, and a valve, wherein the first stent comprises at least one different material property than the second stent. The method further includes delivering the multi-layered stent assembly to the desired implantation location of the patient using a delivery system and substantially simultaneously expanding the first stent and the second stent of the multi-layered stent assembly at the desired implantation location to a radially expanded size that is larger than the compressed size.

    摘要翻译： 一种将多层支架组件经皮递送到患者期望的植入位置的方法，包括将多层支架组件径向压缩至压缩尺寸以便植入患者的步骤，所述多层支架组件包括第一 支架，同轴地定位在第一支架的长度的至少一部分中的第二支架和阀，其中第一支架包括与第二支架相比的至少一种不同的材料特性。 该方法还包括使用递送系统将多层支架组件递送到患者的期望植入位置，并且将所述多层支架组件的第一支架和第二支架基本上同时地扩展到期望的植入位置，以径向扩张 尺寸大于压缩尺寸。

    Method and apparatus for providing intra-pericardial access
    79.
    发明授权
    Method and apparatus for providing intra-pericardial access 有权
    用于提供心包内通路的方法和装置

    公开(公告)号：US07207988B2

    公开(公告)日：2007-04-24

    申请号：US10606908

    申请日：2003-06-26

    申请人： Michael E. Leckrone ,  Timothy G. Laske ,  Michael Ujhelyi

    发明人： Michael E. Leckrone ,  Timothy G. Laske ,  Michael Ujhelyi

    IPC分类号： A61B18/14

    CPC分类号： A61B17/3478 ,  A61B17/3417 ,  A61B18/1492 ,  A61B2017/00247 ,  A61B2017/22077 ,  A61B2017/3443 ,  A61B2017/3484 ,  A61B2017/3488 ,  A61B2017/349 ,  A61B2018/00291 ,  A61B2018/00357 ,  A61B2018/00392

    摘要： A method and apparatus for accessing the pericardial space which provides for stable short term or long term placement of a delivery catheter or cannula having its distal most end located in the pericardial space. The catheter or cannula may be introduced into the pericardial space either transvenously through the wall of a heart chamber or transthoracically by penetrating the chest wall and the pericardium. Some embodiments are provided with a mechanism for stabilizing the distal end of the catheter or cannula, which mechanism may employ an extensible elastic, generally tubular member located at the distal end of the catheter or cannula. The device may be provided with a mechanism for extending the tubular member longitudinally, causing its diameter to diminish substantially. The tubular member may be passed through the wall of the heart or the pericardium in its extended configuration and thereafter, the distal-most portion of the tubular member may be moved proximally, causing its diameter enlarge, anchoring the distal end of the catheter or cannula to the pericardium or to the wall of a heart chamber. In these embodiments, the device is preferably provided with a shoulder or flange located proximal to the extendible tubular member, for location on the opposite side of the heart wall or pericardium from the distal end of the catheter or cannula.

    摘要翻译： 一种用于进入心包空间的方法和装置，其提供其最远端位于心包空间中的输送导管或插管的稳定的短期或长期放置。 导管或插管可以通过穿透胸壁和心包而经心脏穿过心室的壁或经胸腔引入心包空间。 一些实施例设置有用于稳定导管或插管的远端的机构，该机构可以使用位于导管或插管的远端处的可伸展的弹性大体管状构件。 该装置可以设置有用于纵向延伸管状构件的机构，从而使其直径基本上减小。 管状构件可以以其延伸构型穿过心脏壁或心包，此后，管状构件的最远端部分可以向近侧移动，导致其直径增大，将导管或套管的远端固定 到心包室或心室的壁。 在这些实施例中，装置优选地设置有位于可伸缩管状构件的近侧的肩部或凸缘，用于位于与导管或插管远端的心脏壁或心包相反的一侧。

    Medical electrical lead anchoring
    80.
    发明授权
    Medical electrical lead anchoring 有权
    医用电气导线锚定

    公开(公告)号：US07184842B2

    公开(公告)日：2007-02-27

    申请号：US10664995

    申请日：2003-09-17

    申请人： Kevin R. Seifert ,  Timothy G. Laske

    发明人： Kevin R. Seifert ,  Timothy G. Laske

    IPC分类号： A61N1/05

    CPC分类号： A61N1/0587 ,  A61N1/059 ,  A61N2001/0578

    摘要： A lead body of a medical electrical lead includes a distal end, a first elongated insulated conductor extending toward the distal end and a first electrode coupled to the conductor. A second elongated insulated conductor includes a first portion extending within the lead body to the distal end and a second portion extending distally from the distal end of the lead body where it is terminated by a tissue anchor on which a second electrode is mounted; the tissue anchor includes a surface for receiving a push force from an insertion tool, which is adapted to insert the anchor within a segment of tissue such that the first electrode of the lead body is in close proximity to the segment of tissue.

    摘要翻译： 医疗电线的引线体包括远端，朝向远端延伸的第一细长绝缘导体和耦合到导体的第一电极。 第二细长绝缘导体包括在引线主体内延伸到远端的第一部分和从引线主体的远端向远端延伸的第二部分，其中第二部分由其上安装有第二电极的组织锚固件终止; 组织锚固件包括用于接收来自插入工具的推力的表面，其适于将锚固件插入组织段内，使得引线主体的第一电极紧邻组织段。