公开(公告)号：US5648250A

公开(公告)日：1997-07-15

申请号：US412859

申请日：1995-03-29

申请人： Mineo Niwa ,  Yoshimasa Saito ,  Hitoshi Sasaki ,  Masako Hayashi ,  Jouji Notani ,  Masakazu Kobayashi

发明人： Mineo Niwa ,  Yoshimasa Saito ,  Hitoshi Sasaki ,  Masako Hayashi ,  Jouji Notani ,  Masakazu Kobayashi

IPC分类号： C12N15/09 ,  A61K38/46 ,  A61K38/48 ,  A61P7/02 ,  C07H21/04 ,  C07K14/745 ,  C12N1/20 ,  C12N1/21 ,  C12N5/10 ,  C12N9/64 ,  C12N9/72 ,  C12N15/58 ,  C12R1/19 ,  C12R1/91 ,  C12N15/70 ,  A61K38/49

CPC分类号： C12N9/6459 ,  C12Y304/21069

摘要： The invention relates to a new tissue plasminogen activator which has strong activity for converting plasminogen into plasmin that degrades the fibrin network of blood clots to form soluble products and therefore is useful as a thrombolytic agent. The invention also relates to a DNA sequence encoding the amino acid sequence for the tissue plasminogen activator, to a process for producing the plasminogen activator, and to a pharmaceutical composition comprising the new tissue plasminogen activator.

摘要翻译： 本发明涉及一种新的组织纤溶酶原激活剂，其具有将纤溶酶原转化成纤溶酶的强烈活性，其使血凝块的纤维蛋白网络降解形成可溶性产物，因此可用作血栓溶解剂。 本发明还涉及编码组织纤溶酶原激活剂的氨基酸序列的DNA序列，以及制备纤溶酶原激活物的方法，以及包含新组织纤溶酶原激活剂的药物组合物。

公开(公告)号：USRE35496E

公开(公告)日：1997-04-29

申请号：US525174

申请日：1995-09-08

申请人： Ken Yamamura ,  Naoto Ueda ,  Kazunari Michii ,  Hitoshi Fujimoto ,  Kiyoaki Tsumura ,  Hitoshi Sasaki ,  Takashi Miyamoto

发明人： Ken Yamamura ,  Naoto Ueda ,  Kazunari Michii ,  Hitoshi Fujimoto ,  Kiyoaki Tsumura ,  Hitoshi Sasaki ,  Takashi Miyamoto

IPC分类号： H01L21/60 ,  H01L23/485 ,  H01L23/495 ,  H01L23/02 ,  H01L23/08 ,  H01L43/00

CPC分类号： H01L24/85 ,  H01L23/49503 ,  H01L23/4951 ,  H01L23/49537 ,  H01L23/49551 ,  H01L24/05 ,  H01L24/06 ,  H01L24/48 ,  H01L24/49 ,  H01L24/97 ,  H01L2224/04042 ,  H01L2224/05554 ,  H01L2224/05599 ,  H01L2224/06136 ,  H01L2224/45015 ,  H01L2224/45144 ,  H01L2224/48091 ,  H01L2224/48247 ,  H01L2224/48253 ,  H01L2224/4826 ,  H01L2224/48465 ,  H01L2224/48599 ,  H01L2224/4899 ,  H01L2224/49171 ,  H01L2224/78301 ,  H01L2224/85181 ,  H01L2224/85205 ,  H01L24/45 ,  H01L24/78 ,  H01L2924/00014 ,  H01L2924/01005 ,  H01L2924/01006 ,  H01L2924/01015 ,  H01L2924/0102 ,  H01L2924/01033 ,  H01L2924/01068 ,  H01L2924/01079 ,  H01L2924/01082 ,  H01L2924/014 ,  H01L2924/181 ,  H01L2924/20752 ,  H01L2924/20753 ,  H01L2924/30105 ,  Y10T29/49146 ,  Y10T29/49158 ,  Y10T29/49169 ,  Y10T29/49171

摘要： A semiconductor device of the present invention accommodates a large semiconductor chip in a downsized package without impairing its reliability. The semiconductor chip is bonded on a relatively small die pad. Common inner leads and a plurality of inner leads are disposed opposite and spaced from the semiconductor chip by a gap ranging from 0.1 mm to 0.4 mm and the gap between the semiconductor chip and the common inner leads and the plurality of inner leads is filled with a resin which forms pan of a resin package.

摘要翻译： 本发明的半导体器件在小尺寸封装中容纳大型半导体芯片，而不损害其可靠性。 半导体芯片被接合在相对较小的管芯焊盘上。 通常的内部引线和多个内部引线与半导体芯片相对设置并间隔0.1mm至0.4mm的间隙，并且半导体芯片与公共内部引线之间的间隙以及多个内部引线填充有 形成树脂包装盘的树脂。

公开(公告)号：US5470419A

公开(公告)日：1995-11-28

申请号：US170990

申请日：1993-12-21

申请人： Hitoshi Sasaki ,  Yuikio Kobayashi ,  Shyoji Igota

发明人： Hitoshi Sasaki ,  Yuikio Kobayashi ,  Shyoji Igota

IPC分类号： B65D77/32 ,  B29C37/00 ,  B29C47/02 ,  B29C47/06 ,  B29C70/82 ,  B29K105/20 ,  B29L7/00 ,  B65D33/00 ,  B65D75/58 ,  B29C47/00

CPC分类号： B29C47/065 ,  B29C47/0021 ,  B29C47/0047 ,  B29C70/82 ,  B65D75/5844 ,  B29C37/0057 ,  B29C47/003 ,  Y10S493/93 ,  Y10S493/963 ,  Y10T428/24

摘要： An easily tearable plastic film and a pouch made therefrom comprises a thin-wall part for easy tearing. The thin-wall part being made by incorporating strings in the plastic film when it is made by melt extrusion. A method for producing the film and pouch is also shown.

摘要翻译： 容易撕裂的塑料膜和由其制成的袋包括易于撕裂的薄壁部分。 薄壁部分是通过将熔融挤出制成的塑料薄膜中的丝束并入而制成的。 还示出了制造膜和袋的方法。

公开(公告)号：US4988013A

公开(公告)日：1991-01-29

申请号：US288559

申请日：1988-12-22

申请人： Yukio Kobayashi ,  Hitoshi Sasaki ,  Shoji Igota

发明人： Yukio Kobayashi ,  Hitoshi Sasaki ,  Shoji Igota

IPC分类号： B65D17/28 ,  B29C45/14 ,  B29C65/76 ,  B65D17/40

CPC分类号： B65D17/163 ,  B29C45/14811 ,  B29C66/30325 ,  B65D2517/0088

摘要： A container lid structure made essentially of plastics. The lid structure includes a lid frame and a lid plate. The lid plate includes an inner layer comprising a metal foil coated at the opposite sides by plastic layers and connected at the peripheral portion with the lid frame and a core made of a material which is not adhesive to or has a weak bonding power with the plastic material for the lid frame and for the plastic layer of the inner layer. The core is laid over the inner layer with the peripheral portion in an abutting relationship with the inner periphery of the lid frame. A holding member is formed on the core and bonded to the inner layer through apertures in the core. A pulling tab is also formed on the core and bonded to the inner layer through an aperture in the core.

公开(公告)号：US4986995A

公开(公告)日：1991-01-22

申请号：US454934

申请日：1989-12-22

申请人： Yukio Kobayashi ,  Hitoshi Sasaki ,  Norishige Matsuo ,  Mitsuru Ohba

发明人： Yukio Kobayashi ,  Hitoshi Sasaki ,  Norishige Matsuo ,  Mitsuru Ohba

IPC分类号： B65D81/34 ,  A23B9/02 ,  A23L7/10 ,  A23L7/196 ,  B65D81/24 ,  A23B9/20

CPC分类号： A23B9/02 ,  A23L7/196

摘要： A process for producing retort boiled rice by charging raw rice and water into a container, adjusting the quantity of oxygen in the head space of the container to from 4-12 ml/100 g of raw rice, sealing the container and then boiling and sterilizing the rice.

摘要翻译： 通过将生米饭和水装入容器中，将容器的顶部空间中的氧气量调节为4-12ml / 100g生米，将容器密封，然后煮沸灭菌 米饭。