公开(公告)号：US20050251207A1

公开(公告)日：2005-11-10

申请号：US10841411

申请日：2004-05-07

申请人： Jesus Flores ,  Richard Ewers ,  Tracy Maahs ,  Alex Khairkhahan ,  Ruey-Feng Peh ,  Vahid Saadat

发明人： Jesus Flores ,  Richard Ewers ,  Tracy Maahs ,  Alex Khairkhahan ,  Ruey-Feng Peh ,  Vahid Saadat

IPC分类号： A61B17/00 ,  A61B17/04 ,  A61B17/06

CPC分类号： A61B17/0469 ,  A61B17/00234 ,  A61B17/0487 ,  A61B2017/00827 ,  A61B2017/00867 ,  A61B2017/0409 ,  A61B2017/0417 ,  A61B2017/0419 ,  A61B2017/0445 ,  A61B2017/0446 ,  A61B2017/045 ,  A61B2017/0451 ,  A61B2017/0454 ,  A61B2017/0456 ,  A61B2017/0458 ,  A61B2017/0459 ,  A61B2017/0461 ,  A61B2017/0464 ,  A61B2017/0475 ,  A61B2017/0477 ,  A61B2017/0488 ,  A61B2017/0496 ,  A61B2017/06028 ,  A61B2017/06052 ,  A61B2017/06176 ,  Y10T24/39 ,  Y10T24/3969

摘要： Apparatus and methods for positioning and securing anchors are disclosed herein. The anchors are adapted to be delivered and implanted into or upon tissue, particularly tissue within the gastrointestinal system of a patient. The anchor is adapted to slide uni-directionally over suture such that a tissue plication may be cinched between anchors. A locking mechanism either within the anchor itself of positioned proximally of the anchor may allow for the uni-directional translation while enabling the anchor to be locked onto the suture if the anchor is pulled, pushed, or otherwise urged in the opposite direction along the suture. This uni-directional anchor locking mechanism facilitates the cinching of the tissue plication between the anchors and it may be utilized in one or several anchors in cinching a tissue fold.

公开(公告)号：US20050251202A1

公开(公告)日：2005-11-10

申请号：US10955244

申请日：2004-09-30

申请人： Richard Ewers ,  Tracy Maahs ,  Cang Lam ,  Vahid Saadat ,  Chris Rothe

发明人： Richard Ewers ,  Tracy Maahs ,  Cang Lam ,  Vahid Saadat ,  Chris Rothe

IPC分类号： A61B17/00 ,  A61B17/04 ,  A61B17/06 ,  A61B17/064 ,  A61B17/08 ,  A61B17/10 ,  A61B17/28 ,  A61B17/34

CPC分类号： A61B17/0401 ,  A61B17/0469 ,  A61B17/0487 ,  A61B17/06066 ,  A61B17/064 ,  A61B17/08 ,  A61B17/10 ,  A61B17/29 ,  A61B2017/00867 ,  A61B2017/0404 ,  A61B2017/0409 ,  A61B2017/0417 ,  A61B2017/0419 ,  A61B2017/0445 ,  A61B2017/0446 ,  A61B2017/045 ,  A61B2017/0451 ,  A61B2017/0454 ,  A61B2017/0456 ,  A61B2017/0458 ,  A61B2017/0459 ,  A61B2017/0461 ,  A61B2017/0462 ,  A61B2017/0464 ,  A61B2017/0475 ,  A61B2017/0488 ,  A61B2017/0496 ,  A61B2017/06052 ,  A61B2017/081 ,  A61B2017/3488

摘要： Interlocking tissue anchor apparatus and methods are described herein. In creating tissue folds within the body of a patient, a tissue manipulation assembly may generally have an elongate tubular member, an engagement member slidably disposed through the tubular member and a distal end adapted to engage tissue via a helical member, tissue stabilizing members positioned at the tubular member distal end which are adapted to stabilize tissue therebetween, and a delivery tube pivotable about the tissue stabilizer. Anchor assemblies can be delivered via the tissue manipulation assembly into or through the tissue. The anchors can incorporate various temporary interlocking features or spacing elements between one another to ensure that an anchor is not prematurely ejected from the needle assembly. This allows the anchor assembly to be advanced distally as well as withdrawn proximally within a deployment sheath while avoiding inadvertently ejecting an anchor.

摘要翻译： 本文描述了联锁组织锚装置和方法。 在组织折叠在患者体内产生时，组织操作组件通常可以具有细长的管状构件，可滑动地设置穿过管状构件的接合构件和适于通过螺旋构件接合组织的远端，组织稳定构件 所述管状构件远端适于在其间稳定组织，以及可围绕所述组织稳定器枢转的输送管。 锚固组件可以经由组织操纵组件输送到组织或穿过组织。 锚固件可以在彼此之间结合各种临时互锁特征或间隔元件，以确保锚不会从针组件过早地弹出。 这允许锚固组件在部署护套内远端地向远侧推进，同时避免无意中弹出锚固件。

公开(公告)号：US20050251177A1

公开(公告)日：2005-11-10

申请号：US11118876

申请日：2005-04-28

申请人： Vahid Saadat ,  Cang Lam

发明人： Vahid Saadat ,  Cang Lam

IPC分类号： A61B1/00 ,  A61B17/00 ,  A61B17/04 ,  A61B17/06 ,  A61B17/08 ,  A61B17/28 ,  A61B17/34 ,  A61B19/00

CPC分类号： A61F5/0086 ,  A61B17/0401 ,  A61B17/0487 ,  A61B17/06066 ,  A61B17/06114 ,  A61B17/29 ,  A61B2017/00349 ,  A61B2017/00867 ,  A61B2017/00876 ,  A61B2017/0404 ,  A61B2017/0409 ,  A61B2017/0417 ,  A61B2017/0419 ,  A61B2017/0458 ,  A61B2017/0464 ,  A61B2017/0496 ,  A61B2017/06052 ,  A61B2017/06076 ,  A61B2017/2923 ,  A61B2017/2927 ,  A61B2017/3488 ,  A61B2090/037

摘要： Apparatus and methods for rapid deployment of tissue anchors are described herein. A tissue manipulation assembly is pivotably coupled to the distal end of a tubular member and has a lower jaw member and an upper jaw member pivotably coupled to the lower jaw member. A reconfigurable launch tube is pivotably coupled to the upper jaw member and is used to urge the jaw members from a low-profile configuration to an open configuration. A needle assembly can be advanced through the launch tube across tissue received between the jaw members of the tissue manipulation assembly. Tissue anchors can be advanced through the needle assembly for securing received tissue. The tissue anchors can be positioned within a reloadable chamber of a control handle disposed outside the patient, then advanced through the needle assembly.

摘要翻译： 本文描述了用于组织锚的快速展开的装置和方法。 组织操作组件可枢转地联接到管状构件的远端，并且具有下颚构件和可枢转地联接到下颚构件的上颚构件。 可重新配置的发射管可枢转地联接到上钳口构件并且用于将钳口构件从低轮廓构造推动到打开构型。 针组件可以穿过发射管穿过组织操纵组件的钳口构件之间的组织。 组织锚可以通过针组件前进，以固定接收到的组织。 组织锚固件可以定位在设置在患者外部的控制手柄的可重新加载的腔室内，然后通过针组件前进。

公开(公告)号：US20050251160A1

公开(公告)日：2005-11-10

申请号：US10954666

申请日：2004-09-29

申请人： Vahid Saadat ,  Richard Ewers ,  Cang Lam ,  Robert Vaughan ,  Chris Rothe ,  Kenneth Michlitsch

发明人： Vahid Saadat ,  Richard Ewers ,  Cang Lam ,  Robert Vaughan ,  Chris Rothe ,  Kenneth Michlitsch

IPC分类号： A61B17/00 ,  A61B17/04 ,  A61B17/06 ,  A61B17/064 ,  A61B17/08 ,  A61B17/10 ,  A61B17/28 ,  A61B17/34

CPC分类号： A61F5/0086 ,  A61B17/0401 ,  A61B17/0469 ,  A61B17/0482 ,  A61B17/0483 ,  A61B17/0487 ,  A61B17/06 ,  A61B17/06066 ,  A61B17/064 ,  A61B17/08 ,  A61B17/10 ,  A61B17/12013 ,  A61B17/1285 ,  A61B17/29 ,  A61B2017/00867 ,  A61B2017/0404 ,  A61B2017/0409 ,  A61B2017/0417 ,  A61B2017/0419 ,  A61B2017/0445 ,  A61B2017/0446 ,  A61B2017/045 ,  A61B2017/0451 ,  A61B2017/0454 ,  A61B2017/0456 ,  A61B2017/0458 ,  A61B2017/0459 ,  A61B2017/0461 ,  A61B2017/0462 ,  A61B2017/0464 ,  A61B2017/0475 ,  A61B2017/0488 ,  A61B2017/0496 ,  A61B2017/06052 ,  A61B2017/081 ,  A61B2017/3488

摘要： Apparatus for manipulating and securing tissue are described herein. In creating tissue folds within the body of a patient, a tissue manipulation assembly may generally have an elongate tubular member, an engagement member slidably disposed through the tubular member and a distal end adapted to engage tissue via a helical member, tissue stabilizing members positioned at the tubular member distal end which are adapted to stabilize tissue therebetween, and a delivery tube pivotable about the tissue stabilizer. The stabilizing members can be adapted to become angled relative to a longitudinal axis of the elongate tubular member. Moreover, one or all the articulation controls and functions can be integrated into a singular handle assembly connectable to the tissue manipulation assembly via a rigid or flexible tubular body.

摘要翻译： 本文描述了用于操纵和固定组织的装置。 在组织折叠在患者体内产生时，组织操作组件通常可以具有细长的管状构件，可滑动地设置穿过管状构件的接合构件和适于通过螺旋构件接合组织的远端，组织稳定构件 所述管状构件远端适于在其间稳定组织，以及可围绕所述组织稳定器枢转的输送管。 稳定构件可以适于相对于细长管状构件的纵向轴线成角度。 此外，一个或所有关节运动控制和功能可以集成到通过刚性或柔性管状体连接到组织操作组件的单个手柄组件中。

公开(公告)号：US06960163B2

公开(公告)日：2005-11-01

申请号：US10281462

申请日：2002-10-25

申请人： Richard C. Ewers ,  Vahid Saadat

发明人： Richard C. Ewers ,  Vahid Saadat

IPC分类号： A61B1/005 ,  A61B1/008 ,  A61B1/01 ,  A61B1/31 ,  A61B1/32 ,  A61B1/00

CPC分类号： A61B1/00154 ,  A61B1/00078 ,  A61B1/0008 ,  A61B1/00082 ,  A61B1/00105 ,  A61B1/00135 ,  A61B1/0052 ,  A61B1/0055 ,  A61B1/0058 ,  A61B1/008 ,  A61B1/31 ,  A61B1/32

摘要： Apparatus and methods are provided for placing and advancing a diagnostic or therapeutic instrument in a hollow body organ of a tortuous or unsupported anatomy, comprising a handle, an overtube disposed within a hydrophilic sheath, and a distal region having an atraumatic tip. The overtube may be removable from the handle, and have a longitudinal axis disposed at an angle relative to the handle. The sheath may be disposable to permit reuse of the overtube. Fail-safe tensioning mechanisms may be provided to selectively stiffen the overtube to reduce distension of the organ caused by advancement of the diagnostic or therapeutic instrument. The fail-safe tensioning mechanisms reduce the risk of reconfiguration of the overtube in the event that the tension system fails, and, in one embodiment, rigidizes the overtube without substantial proximal movement of the distal region. The distal region permits passive steering of the overtube caused by deflection of the diagnostic or therapeutic instrument, while the atraumatic tip prevents the wall of the organ from becoming caught or pinched during manipulation of the diagnostic or therapeutic instrument.

公开(公告)号：US20050171585A1

公开(公告)日：2005-08-04

申请号：US11096980

申请日：2005-04-01

申请人： Vahid Saadat

发明人： Vahid Saadat

IPC分类号： A61B17/00 ,  A61F7/00 ,  A61F7/12 ,  A61M1/36 ,  A61M19/00

CPC分类号： A61F7/12 ,  A61F2007/0056 ,  A61F2007/0075 ,  A61F2007/126

摘要： Apparatus and methods for cooling selected regions within a body are described herein. An implantable cooling system is used to cool regions of the brain, spinal cord, fibrous nerve bodies, e.g., vagus nerve, etc. down to about 30° C. to diminish nerve impulses which control seizures or chronic pain. The system includes an implantable unit containing a pumping mechanism and/or various control electronics. It also has a heat exchanger attachable to a tubular body organ, such as the superior vena cava or the inferior vena cava, through which the heat is effectively dissipated. Also included is a heat pump such as a Peltier junction configured to be placed into contact with the region of tissue to be cooled. The heated portion of the Peltier junction is cooled by a liquid heat transfer medium which absorbs the heat from the junction and dissipates it into the tubular body organ.

摘要翻译： 本文描述了用于冷却体内所选区域的装置和方法。 植入式冷却系统用于将大脑，脊髓，纤维神经体（例如迷走神经等）的区域冷却至约30℃，以减少控制癫痫发作或慢性疼痛的神经冲动。 该系统包括含有泵送机构和/或各种控制电子装置的可植入单元。 它还具有可连接到诸如上腔静脉或下腔静脉的管状体器官的热交换器，热量被有效地消散通过该热交换器。 还包括一个热泵，例如珀尔帖接头，被配置为与要冷却的组织区域接触。 珀尔帖接头的加热部分由液体传热介质冷却，液体传热介质从接合处吸收热量并将其散发到管状体脏器中。

公开(公告)号：US20050137456A1

公开(公告)日：2005-06-23

申请号：US10888531

申请日：2004-07-08

申请人： Vahid Saadat ,  Richard Ewers ,  Eugene Chen

发明人： Vahid Saadat ,  Richard Ewers ,  Eugene Chen

IPC分类号： A61B1/005 ,  A61B1/008 ,  A61B1/01 ,  A61B1/31 ,  A61B1/32 ,  A61B1/00

CPC分类号： A61B1/0052 ,  A61B1/00078 ,  A61B1/0008 ,  A61B1/00082 ,  A61B1/00105 ,  A61B1/00135 ,  A61B1/00154 ,  A61B1/0055 ,  A61B1/0057 ,  A61B1/0058 ,  A61B1/31 ,  A61B1/32

摘要： Apparatus and methods are provided for placing and advancing a diagnostic or therapeutic instrument in a hollow body organ of a tortuous or unsupported anatomy, comprising a handle, an overtube, a distal region having an atraumatic tip. The overtube may be removable from the handle, and have a longitudinal axis disposed at an angle relative to the handle. The overtube may be selectively stiffened to reduce distension of the organ caused by advancement of the diagnostic or therapeutic instrument. The distal region permits passive steering of the overtube caused by deflection of the diagnostic or therapeutic instrument while the atraumatic tip prevents the wall of the organ from becoming caught or pinched during manipulation of the diagnostic or therapeutic instrument.

公开(公告)号：US20050137454A1

公开(公告)日：2005-06-23

申请号：US10888083

申请日：2004-07-08

申请人： Vahid Saadat ,  Richard Ewers ,  Eugene Chen

发明人： Vahid Saadat ,  Richard Ewers ,  Eugene Chen

IPC分类号： A61B1/005 ,  A61B1/01 ,  A61B1/31 ,  A61B1/32 ,  A61B1/00 ,  A61B1/04

CPC分类号： A61B1/0052 ,  A61B1/00078 ,  A61B1/0008 ,  A61B1/00082 ,  A61B1/00135 ,  A61B1/0055 ,  A61B1/0057 ,  A61B1/31 ,  A61B1/32

摘要： Apparatus and methods are provided for placing and advancing a diagnostic or therapeutic instrument in a hollow body organ of a tortuous or unsupported anatomy, comprising a handle, an overtube, a distal region having an atraumatic tip. The overtube may be removable from the handle, and have a longitudinal axis disposed at an angle relative to the handle. The overtube may be selectively stiffened to reduce distension of the organ caused by advancement of the diagnostic or therapeutic instrument. The distal region permits passive steering of the overtube caused by deflection of the diagnostic or therapeutic instrument while the atraumatic tip prevents the wall of the organ from becoming caught or pinched during manipulation of the diagnostic or therapeutic instrument.

公开(公告)号：US06746474B2

公开(公告)日：2004-06-08

申请号：US10159713

申请日：2002-05-31

申请人： Vahid Saadat

发明人： Vahid Saadat

IPC分类号： A61F700

CPC分类号： A61F7/12 ,  A61F2007/0056 ,  A61F2007/0075 ,  A61F2007/126

摘要： Apparatus and methods for cooling selected regions within a body are described herein. An implantable cooling system is used to cool regions of the brain, spinal cord, fibrous nerve bodies, e.g., vagus nerve, etc. down to about 30° C. to diminish nerve impulses which control seizures or chronic pain. The system includes an implantable unit containing a pumping mechanism and/or various control electronics. It also has a heat exchanger attachable to a tubular body organ, such as the superior vena cava or the inferior vena cava, through which the heat is effectively dissipated. Also included is a heat pump such as a Peltier junction configured to be placed into contact with the region of tissue to be cooled. The heated portion of the Peltier junction is cooled by a liquid heat transfer medium which absorbs the heat from the junction and dissipates it into the tubular body organ.

摘要翻译： 本文描述了用于冷却体内所选区域的装置和方法。 植入式冷却系统用于将大脑，脊髓，纤维神经体（例如迷走神经等）的区域冷却至约30℃，以减少控制癫痫发作或慢性疼痛的神经冲动。 该系统包括含有泵送机构和/或各种控制电子装置的可植入单元。 它还具有可连接到诸如上腔静脉或下腔静脉的管状体器官的热交换器，热量被有效地消散通过该热交换器。 还包括一个热泵，例如珀尔帖接头，被配置为与要冷却的组织区域接触。 珀尔帖接头的加热部分由液体传热介质冷却，液体传热介质从接合处吸收热量并将其散发到管状体脏器中。

公开(公告)号：US6010476A

公开(公告)日：2000-01-04

申请号：US953769

申请日：1997-10-17

申请人： Vahid Saadat

发明人： Vahid Saadat

IPC分类号： A61B17/00 ,  A61B17/22 ,  A61B17/34 ,  A61B18/14 ,  A61B19/00 ,  A61B17/32

CPC分类号： A61B17/3207 ,  A61B18/148 ,  A61B18/1492 ,  A61B2017/00022 ,  A61B2017/00026 ,  A61B2017/00247 ,  A61B2017/22077 ,  A61B2017/3488 ,  A61B2018/00196 ,  A61B2018/00208 ,  A61B2018/00291 ,  A61B2018/00392 ,  A61B2018/00738 ,  A61B2018/00761 ,  A61B2018/00916 ,  A61B2018/124 ,  A61B2018/1437 ,  A61B2018/1861 ,  A61B2090/3782 ,  A61B2218/002 ,  A61B2218/007 ,  A61B34/20 ,  A61B90/37

摘要： Apparatus and methods for intraoperatively performing surgery to create transmural channels in tissue, for example, as in transmyocardial revascularization, are provided using a device including a mechanical end effector and means for stabilizing the end effector in contact with the tissue. The end effector is adapted to cooperate with a source of suction to evacuate tissue severed during the channel forming process, and may optionally include an electrode for cauterizing the tissue surrounding the channel.

摘要翻译： 使用包括机械末端执行器的装置和用于稳定与组织接触的末端执行器的装置来提供用于在手术中进行手术以在组织中产生透壁通道的装置和方法，例如在心肌血运重建中。 端部执行器适于与吸入源协作以排出在通道形成过程期间切断的组织，并且可任选地包括用于烧灼围绕通道的组织的电极。