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104 条记录 (耗时 0.029 秒)

    Dimensional stabilization of slab gel cassettes to prevent distortion caused by swelling gels
    81.
    发明授权
    Dimensional stabilization of slab gel cassettes to prevent distortion caused by swelling gels 有权
    尺寸凝胶盒的尺寸稳定性，以防止由溶胀凝胶引起的变形

    公开(公告)号：US09234874B2

    公开(公告)日：2016-01-12

    申请号：US13371667

    申请日：2012-02-13

    申请人： Cory Panattoni ,  Matthew Latham ,  Kara Kimmel ,  John Walker

    发明人： Cory Panattoni ,  Matthew Latham ,  Kara Kimmel ,  John Walker

    IPC分类号： B29C39/26 ,  G01N27/447 ,  B29C39/02

    CPC分类号： G01N27/44704 ,  B29C39/02 ,  G01N27/44756

    摘要： Slab gel cassettes for use in electrophoretic analyzes of biologically-derived mixtures are equipped with features that prevent the plastic walls of the cassettes from bowing outward when gels retained within the cassettes swell, as gels typically do during casting, storage, or both. In certain embodiments, these features are incorporated into, or mate with, the comb-shaped inserts that form the sample wells as the gels are being cast. In other embodiments, these features are complementary features incorporated into both the comb and the cassette.

    摘要翻译： 用于生物衍生混合物的电泳分析的板状凝胶盒配备有特征，其防止胶片的塑料壁在保持在盒内的凝胶溶胀时向外弯曲，如凝胶通常在铸造，储存或两者期间一样。 在某些实施方案中，当凝胶凝固时，将这些特征结合到形成样品孔的梳状插入物中或与其配合。 在其他实施例中，这些特征是并入梳子和盒子中的互补特征。

    Saponin adjuvant compositions and methods relating thereto
    82.
    发明授权
    Saponin adjuvant compositions and methods relating thereto 有权
    皂苷佐剂组合物及其相关方法

    公开(公告)号：US09149520B2

    公开(公告)日：2015-10-06

    申请号：US13420082

    申请日：2012-03-14

    申请人： John Walker

    发明人： John Walker

    IPC分类号： A61K39/395 ,  A61K39/39 ,  A61K39/00

    CPC分类号： A61K39/39591 ,  A61K39/0006 ,  A61K39/39 ,  A61K47/183 ,  A61K2039/55577 ,  A61K2039/55583

    摘要： An adjuvant composition which comprises an anionic macromolecule component particularly an ionic polysaccharide such as DEAE-dextran, and a saponin component, particularly an immunostimulating complex component. Immunogenic compositions comprising an immunogen and this adjuvant composition are also disclosed together with methods of use thereof.

    摘要翻译： 一种佐剂组合物，其包含阴离子大分子组分，特别是离子多糖如DEAE-葡聚糖和皂苷组分，特别是免疫刺激复合物组分。 还公开了包含免疫原和该佐剂组合物的免疫原性组合物及其使用方法。

    Security chip
    84.
    发明授权
    Security chip 有权
    安全芯片

    公开(公告)号：US08410583B2

    公开(公告)日：2013-04-02

    申请号：US12733188

    申请日：2008-08-04

    申请人： John Walker ,  Tony Boswell

    发明人： John Walker ,  Tony Boswell

    IPC分类号： H01L23/552 ,  H01L23/58 ,  H01L21/70 ,  H01L21/00 ,  H01L21/8238

    CPC分类号： H01L23/573 ,  G06K19/07327 ,  H01L23/576 ,  H01L2924/0002 ,  H01L2924/00

    摘要： A security chip is disclosed. The security chip includes: a substrate; an integrated circuit disposed on the substrate, the integrated circuit including circuit elements, circuit interconnect layers connecting the circuit elements together, and interlayer contacts supporting the circuit interconnect layers; a shield to at least partially shield the integrated circuit; and at least one lightwell in the shield and the integrated circuit, wherein each lightwell has a closed shape formed from parts of the circuit interconnect layers and interlayer contacts, wherein no exploitable voltage can be measured on the parts of the circuit interconnect layers and interlayer contacts, and wherein each lightwell forms a path for light to penetrate to the substrate preventing the light from reaching the circuit elements. Related apparatus and methods are also disclosed.

    摘要翻译： 公开了一种安全芯片。 安全芯片包括：基板; 设置在所述基板上的集成电路，所述集成电路包括电路元件，将所述电路元件连接在一起的电路互连层以及支撑所述电路互连层的层间接触; 至少部分屏蔽集成电路的屏蔽; 以及屏蔽和集成电路中的至少一个灯孔，其中每个灯孔具有由电路互连层和层间接触的部分形成的封闭形状，其中在电路互连层和层间触点的部分上不能测量可利用的电压 ，并且其中每个灯井形成用于光穿透到衬底的路径，防止光到达电路元件。 还公开了相关的装置和方法。

    DIMENSIONAL STABILIZATION OF SLAB GEL CASSETTES TO PREVENT DISTORTION CAUSED BY SWELLING GELS
    85.
    发明申请
    DIMENSIONAL STABILIZATION OF SLAB GEL CASSETTES TO PREVENT DISTORTION CAUSED BY SWELLING GELS 审中-公开
    硅胶凝胶的尺寸稳定性以防止由凝胶引起的失真

    公开(公告)号：US20130056909A1

    公开(公告)日：2013-03-07

    申请号：US13371667

    申请日：2012-02-13

    申请人： Cory Panattoni ,  Matthew Latham ,  Kara Kimmel ,  John Walker

    发明人： Cory Panattoni ,  Matthew Latham ,  Kara Kimmel ,  John Walker

    IPC分类号： B29C39/26 ,  B29C39/02

    CPC分类号： G01N27/44704 ,  B29C39/02 ,  G01N27/44756

    摘要： Slab gel cassettes for use in electrophoretic analyses of biologically-derived mixtures are equipped with features that prevent the plastic walls of the cassettes from bowing outward when gels retained within the cassettes swell, as gels typically do during casting, storage, or both. In certain embodiments, these features are incorporated into, or mate with, the comb-shaped inserts that form the sample wells as the gels are being cast. In other embodiments, these features are complementary features incorporated into both the comb and the cassette.

    摘要翻译： 用于生物衍生混合物的电泳分析的板状凝胶盒配备有特征，其防止胶片的塑料壁在保持在盒内的凝胶溶胀时向外弯曲，如凝胶通常在铸造，储存或两者期间一样。 在某些实施方案中，当凝胶凝固时，将这些特征结合到形成样品孔的梳状插入物中或与其配合。 在其他实施例中，这些特征是并入梳子和盒子中的互补特征。

    Depositing Device
    89.
    发明申请
    Depositing Device 有权
    存放设备

    公开(公告)号：US20070207232A1

    公开(公告)日：2007-09-06

    申请号：US10596721

    申请日：2004-12-14

    申请人： Roy Nelson ,  William Coatesworth ,  John Walker ,  Jonathan Sutton ,  Richard Craggs

    发明人： Roy Nelson ,  William Coatesworth ,  John Walker ,  Jonathan Sutton ,  Richard Craggs

    IPC分类号： B29C44/58 ,  B29C45/58 ,  A23B4/16 ,  A23C3/037

    CPC分类号： A23G1/208 ,  A23G1/56 ,  A23G3/02 ,  A23G3/0294 ,  A23G3/346 ,  A23G9/28 ,  A23G2220/02 ,  B05B12/087 ,  B05C5/0225 ,  B29C44/3492 ,  B29K2105/04 ,  B65B39/004

    摘要： The invention is a depositing device (5) for depositing flowable food containing gas comprising a pressurized feed line conveying flowable food containing gas under pressure into the food; piston (60) means operatively connected to the feed line comprising a piston and a chamber (61); an outlet to deliver food at the atmospheric pressure into moulds (85). The device comprises a pressure retaining means (9) arranged to retain the product in the chamber at the same pressure as the line pressure and to deliver the product through the outlet as pressure in the chamber increases from the line pressure upon descent of the piston in the chamber.

    摘要翻译： 本发明是一种用于沉积含有气体的可流动食品的沉积装置（5），包括一个加压进料管线，该压力进料管线将含有气体的可流动食品输送到食品中; 活塞（60）装置可操作地连接到包括活塞和腔室（61）的进料管线; 在大气压力下将食物送入模具（85）的出口。 该装置包括压力保持装置（9），该压力保持装置（9）被布置成在与管线压力相同的压力下将产品保持在腔室中，并且当该腔室中的压力从活塞下降时的管路压力增加时，将产品输送通过出口 房间。

    METHOD FOR DETECTING A LIPOPROTEIN-ACUTE PHASE PROTEIN COMPLEX AND PREDICTING AN INCREASED RISK OF SYSTEM FAILURE OR MORTALITY
    90.
    发明申请
    METHOD FOR DETECTING A LIPOPROTEIN-ACUTE PHASE PROTEIN COMPLEX AND PREDICTING AN INCREASED RISK OF SYSTEM FAILURE OR MORTALITY 审中-公开
    检测脂蛋白激酶相关蛋白复合物的方法和预测系统失效或死亡风险增加的方法

    公开(公告)号：US20070155018A1

    公开(公告)日：2007-07-05

    申请号：US11676483

    申请日：2007-02-19

    申请人： Timothy Fischer ,  Colin Downey ,  Mike Nesheim ,  John Samis ,  Liliana Tejidor ,  Cheng-Hock Toh ,  John Walker

    发明人： Timothy Fischer ,  Colin Downey ,  Mike Nesheim ,  John Samis ,  Liliana Tejidor ,  Cheng-Hock Toh ,  John Walker

    IPC分类号： G01N1/00

    CPC分类号： G01N33/557 ,  G01N33/86 ,  G01N33/92 ,  G01N2800/52 ,  Y10T436/25

    摘要： A method for diagnosing a condition of a patient involves the steps of (a) adding one or more reagents to a test sample from a patient, the test samples comprising at least part of a blood sample from the patient, in order to cause formation of a complex comprising at least one acute phase protein at at least one human lipoprotein, while causing substantially no fiber polymerization; (b) measuring the formation of the complex over time so as to derive a time-dependent measurement profile, and (c) determining a slope and/or total change in the time-dependent measurement profile, so as to diagnose a condition of the patient. A greater formation of the complex is correlated to increased probability of death of the patient.

    摘要翻译： 用于诊断患者状况的方法包括以下步骤：（a）将一种或多种试剂添加到来自患者的测试样品中，所述测试样品包含来自患者的血液样品的至少一部分，以便形成 在至少一种人类脂蛋白中包含至少一种急性期蛋白质的复合物，同时基本上不引起纤维聚合; （b）随着时间的推移测量复合物的形成，以便导出时间相关的测量曲线，以及（c）确定时间依赖性测量曲线的斜率和/或总变化，以诊断 患者。 复合物的更大形成与患者死亡概率增加相关。