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1.发明公开公开(公告)号：US20240317785A1
公开(公告)日：2024-09-26
申请号：US18273312
申请日：2022-01-26
发明人： George K. H. Shimizu , David Evans , Evan Gabert , Martin Glavinovic , Racheal Huynh , Daniel Padeanu , Justin Perras , Jared Taylor , Jinfeng Zhang
IPC分类号： C07F11/00 , B01D15/08 , B01D53/02 , B01J20/22 , B01J20/30 , H01M8/10 , H01M8/1018 , H01M10/056
CPC分类号： C07F11/005 , B01D15/08 , B01D53/02 , B01J20/226 , B01J20/3085 , B01D2253/204 , H01M8/1018 , H01M2008/1095 , H01M10/056 , H01M2300/0065
摘要： The present application relates to metal-organic frameworks (MOFs). More specifically, the present application relates to process for their preparation and uses thereof. The present application includes a process for preparing a chromium (III) phosphonate metal-organic framework (MOF) comprising: a) dehydrating a hydrogen-bonded metal-organic framework (HMOF) comprising chromium (III) hydrogen bonded to one or more organic polyphosphonate molecule by heating the HMOF at a controlled rate; b) cooling the dehydrated HMOF from a) to provide the MOF.
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公开(公告)号：US20240316191A1
公开(公告)日：2024-09-26
申请号：US18581095
申请日：2024-02-19
CPC分类号： A61K39/39 , A61K39/0011 , A61K2039/55511
摘要： A method of inducing a Type I interferon response in a mammalian subject that presents with a microbial infection, cancerous tumor or hematological malignancy that comprises administering an amount of a halogenated xanthene as discussed above, effective to induce the Type I interferon response. A method of enhancing a mammalian immunogen-specific immune response that comprises contacting mammalian cells, in vivo or present in a mammalian cell growth supporting medium, with an adjuvant-effective amount of a halogenated xanthene, and an immunogen to which that response is to be enhanced. A mammalian HX compound-adjuvanted vaccine composition that contains an immunogen present in a vaccine-effective amount along with an adjuvant-effective amount of a halogenated xanthene (HX) compound and one or more excipients present at about 0.001% by weight to 10% by weight of the vaccine composition dissolved or dispersed in a pharmaceutically acceptable diluent.
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公开(公告)号：US12092549B2
公开(公告)日：2024-09-17
申请号：US16491352
申请日：2018-03-06
CPC分类号： G01M3/045 , B01D17/02 , C02F1/48 , C08J3/11 , C08J3/212 , C08J5/18 , G01M3/18 , C02F2101/32 , C02F2305/08 , C08J2323/06 , C08J2323/12 , C08J2325/06 , C08J2327/18 , C08J2391/06
摘要： An example a method of manufacturing a film is provided. The method involves dissolving a backbone material in a non-aqueous solvent to form a non-aqueous solution. The method further involves adding the non-aqueous solution to an aqueous solution to form a liquid-liquid interface and injecting a particulate proximate to the liquid-liquid interface the non-aqueous solution is then evaporated to form a film containing the particulate. The film may be used in devices such as sensor devices for detecting hydrocarbons.
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4.发明授权公开(公告)号：US12091408B2
公开(公告)日：2024-09-17
申请号：US14915368
申请日：2014-09-27
申请人： Tom Back , Wayne Chen , Chris Smith , Dawei Jiang , UTI Limited Partnership
发明人： Tom Back , Wayne Chen , Chris Smith , Dawei Jiang
IPC分类号： C07D419/12 , C07C217/28 , C07C217/32 , C07C217/34 , C07C217/38 , C07C217/54 , C07C217/92 , C07C233/20 , C07D209/08 , C07D209/88 , C07D215/227 , C07D231/56 , C07D235/06 , C07D235/08 , C07D265/36 , C07D279/16 , C07D279/20 , C07D279/34 , C07D281/10 , C07D401/12 , C07D405/12 , C07D413/12 , C07D417/06
CPC分类号： C07D419/12 , C07C217/28 , C07C217/32 , C07C217/34 , C07C217/38 , C07C217/54 , C07C217/92 , C07C233/20 , C07D209/08 , C07D209/88 , C07D215/227 , C07D231/56 , C07D235/06 , C07D235/08 , C07D265/36 , C07D279/16 , C07D279/20 , C07D279/34 , C07D281/10 , C07D401/12 , C07D405/12 , C07D413/12 , C07D417/06 , C07C2603/18 , C07C2603/74
摘要： The present invention provides compounds having store overload-induced Ca2+ release (SOICR) inhibitory activity and methods for producing and using the same. In particular, compounds of the invention is of the formula: R1—X1-L-X2—R2, wherein R1, X1, L, X2, and R2 are those defined herein.
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公开(公告)号：US11879735B2
公开(公告)日：2024-01-23
申请号：US17298655
申请日：2020-01-23
发明人： Ahmed Youssef , Naser El-Sheimy
摘要： Systems and methods related to gyroscope related applications. A platform having at least one torus shaped channel that is filled with a liquid is used in conjunction with at least one marker to determine the direction of forces applied to the platform. Each marker is neutrally buoyant within the liquid and a marker tracking system is used to determine the displacement of the marker from its resting place after a force has been applied to the platform. The tracking system may be based on at least one digital camera in conjunction with suitable image processing software to determine the marker's position before, during, and after the force has been applied. A gyroscope can be constructed using three such platforms with each platform being orthogonal to the other two. Each platform may have multiple concentric channels with a common center with each channel having a different sensitivity to the applied forces.
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公开(公告)号：US11814291B2
公开(公告)日：2023-11-14
申请号：US17415987
申请日：2019-12-18
IPC分类号： C01B32/168 , C08K3/04 , C01B32/162 , B01J31/22 , B01J37/08 , B01J37/16 , C01B33/40 , C08K9/02 , B82Y30/00
CPC分类号： C01B32/168 , B01J31/2239 , B01J37/08 , B01J37/16 , C01B32/162 , C01B33/40 , C08K3/041 , C08K9/02 , B01J2531/842 , B82Y30/00 , C01B2202/22 , C01P2002/08 , C01P2002/82 , C08K2201/011
摘要： The present invention relates to a nanomaterial comprising a nanoclay having a layered structure and carbon nanotubes being intercalated between layers of the layered of the nanoclay, and manufacturing method thereof.
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7.发明公开公开(公告)号：US20230349886A1
公开(公告)日：2023-11-02
申请号：US17715796
申请日：2022-04-07
发明人： Sergei NOSKOV , Soren WACKER , Henry DUFF , Jiqing GUO
IPC分类号： G01N33/50 , G06N20/00 , G16B15/00 , G16B35/00 , G16B40/00 , G16C20/60 , G01N33/68 , G16B20/00 , G16C20/30 , G06N20/20 , G16H50/00 , G16B15/30 , G16B40/20 , G16B35/20 , G06N5/01 , G06N7/01
CPC分类号： G01N33/5014 , G01N33/6872 , G06N5/01 , G06N7/01 , G06N20/00 , G06N20/20 , G16B15/00 , G16B15/30 , G16B20/00 , G16B35/00 , G16B35/20 , G16B40/00 , G16B40/20 , G16C20/30 , G16C20/60 , G16H50/00 , G16C20/70
摘要： Systems and methods are provided for predicting cardiotoxicity of molecular parameters of a compound. A computer can provide as input to a machine learning algorithm the molecular parameters of the compound. The molecular parameters can include at least structural information about the compound. The machine learning algorithm can have been trained using respective molecular parameters of compounds known to have cardiotoxicity and of compounds known not to have cardiotoxicity. The computer can receive as output from the machine learning algorithm a representation of the predicted cardiotoxicity of each molecular parameter of at least a subset of the molecular parameters of the compound.
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公开(公告)号：US11708276B2
公开(公告)日：2023-07-25
申请号：US16864313
申请日：2020-05-01
发明人： Elsayed Abdelfatah , Steven Bryant
IPC分类号： C01B33/18 , C01G49/08 , C01B33/12 , C09C1/56 , C01B32/914 , C01B32/174 , B22F1/0545 , B82Y40/00
CPC分类号： C01B33/18 , B22F1/0545 , C01B32/174 , C01B32/914 , C01B33/12 , C01G49/08 , C09C1/56 , B82Y40/00 , C01P2004/64
摘要： Methods are disclosed for dispersing nanoparticles in solvents, involving the use of a cationic species and an anionic species, where at least one of the ionic species is soluble in the nonpolar solvent and the other ionic species has a relatively strong affinity for the surface of the nanoparticles. The cationic species and the anionic species together form a cluster of ion pairs shielding the nanoparticles and enhancing their dispersibility in the nonpolar solvent.
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公开(公告)号：US20230094535A1
公开(公告)日：2023-03-30
申请号：US17879892
申请日：2022-08-03
发明人： NASHAAT N. NASSAR , AFIF HETHNAWI
IPC分类号： C02F1/52
摘要： Nanoflocculants are provided that are comprised of nanoparticles of titanomagnetite having anionic surface moieties associated with electrostatically bound polymerized chains of cationic polyacrylamide, further comprising lauryl sulfate moieties adsorbed to the surface of nanoparticles of the titanomagnetite nanoparticles and/or adsorbed to the bound cationic polyacrylamide polymers. These nanoflocculants combine the dual functionalities of the polyacrylamide/lauryl sulfate moieties, as well as the surface activity of titanomagnetite nanomaterials. Process are provided for making and using the disclosed nanoflocculants, including uses for flocculating intimate aqueous dispersions of solids and bitumen.
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公开(公告)号：US20230066365A1
公开(公告)日：2023-03-02
申请号：US17462841
申请日：2021-08-31
摘要： Systems and methods for affecting spin qubits. In a resonator, an optical field is generated using photons. The optical field causes a stress field to form in the resonator as portions of the resonator oscillates. These oscillations, tunable using lasers and/or injection locking, drive spin transitions to thereby affect the population of specific NV spin qubits present in the resonator.
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