公开(公告)号：US06888780B2

公开(公告)日：2005-05-03

申请号：US10799105

申请日：2004-03-12

申请人： William Happer ,  Nicholas N. Kuzma

发明人： William Happer ,  Nicholas N. Kuzma

IPC分类号： G04F5/14 ,  G04B47/00 ,  G01V3/00 ,  G04F5/00 ,  H03L7/26

CPC分类号： G04F5/145 ,  G04F5/14

摘要： The present invention provides a method and system to simultaneously use the microwave and Zeeman end resonances associated with the same sublevel of maximum (or minimum) azimuthal quantum number m to lock both the atomic clock frequency and the magnetic field to definite values. This eliminates the concern about the field dependence of the end-resonance frequency. In an embodiment of the system of the present invention, alkali metal vapor is pumped with circularly-polarized D1 laser light that is intensity-modulated at appropriate resonance frequencies, thereby providing coherent population trapping (CPT) resonances. In another embodiment, pumping with constant-intensity circularly-polarized D1 laser light enhances magnetic resonances that are excited by alternating magnetic fields oscillating at appropriate resonance frequencies. In both embodiments, the resonances are greatly enhanced by concentrating most of the atoms in the initial state of the resonances, and by diminishing the spin-exchange broadening of the resonances. This leads to greater stability of optically pumped atomic clocks. This invention can also be used to operate an atomic magnetometer, where the feedback signal used to stabilize the magnetic field at the alkali-vapor cell can serve as a sensitive measure of the ambient magnetic field.

摘要翻译： 本发明提供一种同时使用与最大（或最小）方位量子数m的相同子级相关联的微波和塞曼端谐振的方法和系统，以将原子时钟频率和磁场两者锁定到确定的值。 这消除了对端部共振频率的场依赖性的担忧。 在本发明的系统的一个实施方案中，碱金属蒸汽被泵送具有以适当共振频率强度调制的圆偏振D 1激光，由此提供相干群体捕获（CPT）共振 。 在另一个实施例中，用恒定强度的圆偏振D 1激光的泵浦增强了通过以合适的共振频率振荡的交变磁场激发的磁共振。 在两个实施例中，通过将大部分原子集中在共振的初始状态中，并且通过减小共振的自旋交换扩展，可以大大提高谐振。 这导致光泵浦原子钟的更大的稳定性。 本发明还可以用于操作原子磁强计，其中用于稳定碱蒸汽单元处的磁场的反馈信号可以用作环境磁场的敏感度量。

公开(公告)号：US06887493B2

公开(公告)日：2005-05-03

申请号：US10387907

申请日：2003-03-13

申请人： Adi Shefer ,  Samuel David Shefer

发明人： Adi Shefer ,  Samuel David Shefer

IPC分类号： A23G1/00 ,  A23G1/54 ,  A23L1/22 ,  A23L2/39 ,  A61F2/00 ,  A61F13/00 ,  A61K8/02 ,  A61K8/04 ,  A61K8/11 ,  A61K8/34 ,  A61K8/49 ,  A61K8/92 ,  A61K9/00 ,  A61K9/127 ,  A61K9/14 ,  A61K9/16 ,  A61K9/50 ,  A61K9/51 ,  A61Q11/00

CPC分类号： A23G1/54 ,  A23L2/39 ,  A23L27/72 ,  A23V2002/00 ,  A61K8/0241 ,  A61K8/11 ,  A61K8/347 ,  A61K8/4926 ,  A61K8/92 ,  A61K8/922 ,  A61K9/006 ,  A61K9/0063 ,  A61K9/1635 ,  A61K9/1641 ,  A61K9/1652 ,  A61K9/5123 ,  A61K2800/412 ,  A61K2800/413 ,  A61K2800/56 ,  A61Q11/00 ,  A23V2200/25

摘要： The present invention relates to an improved controlled release system that can encapsulate different flavors, sensory markers, and active ingredients, or combinations of flavors, sensory markers and various active ingredients and release multiple active ingredients in a consecutive manner, one after the other. The controlled delivery system of the present invention is substantially free-flowing powder formed of solid hydrophobic nanospheres that are encapsulated in a moisture sensitive microspheres. The flavors, and active ingredients encapsulated in the hydrophobic nanospheres, in the water sensitive microsphere, or in both the nano and the microsphere. The flavors and active ingredients encapsulated in the nanospheres can be the same or different from those encapsulated in the microspheres. The encapsulation of different flavors or active agents in the various components of the system, such as nanospheres and microspheres, provides flavor transition (change in flavor character) during the use of the products. The controlled release system of the present invention enhances the stability and bioavailability of wide range of flavors, sensory markers, and other active ingredients, prolong their residence time in the oral cavity, control their release characteristics, and prolong the sensation of flavors and other sensory markers in the mouth to provide long lasting organoleptic perception or long lasting mouthfeel. The invention further relates oral care, food products, and beverages comprising the controlled release system of the present invention.

摘要翻译： 本发明涉及一种改进的控制释放系统，其可以将不同口味，感官标记物和活性成分，或风味剂，感官标记物和各种活性成分的组合包封，并以连续的方式一个接一个地释放多种活性成分。 本发明的受控递送系统是固体疏水性纳米球形成的基本自由流动的粉末，其被包封在湿敏微球体中。 包封在疏水性纳米球中的香料和活性成分，在水敏感性微球中，或纳米和微球中。 包封在纳米球中的风味剂和活性成分可以与包封在微球体中的那些相同或不同。 不同风味剂或活性剂在系统的各种组分（例如纳米球和微球体）中的包封在产品使用期间提供风味转变（风味特征的变化）。 本发明的控制释放系统增强了各种风味，感官标记物和其它活性成分的稳定性和生物利用度，延长了它们在口腔中的停留时间，控制了它们的释放特性，并延长了口味和其他感觉的感觉 口中的标记提供持久的感官感觉或持久的口感。 本发明还涉及包含本发明的控制释放系统的口腔护理，食品和饮料。

公开(公告)号：US06952478B2

公开(公告)日：2005-10-04

申请号：US09850238

申请日：2001-05-07

申请人： Ruby B. Lee ,  Xiao Yang

发明人： Ruby B. Lee ,  Xiao Yang

IPC分类号： G06F7/24 ,  G06F7/76 ,  G06F9/30 ,  G06F9/308 ,  G06F9/315 ,  G09C1/00 ,  H04L29/06 ,  H04K1/04 ,  H04K1/06

CPC分类号： G06F7/762 ,  G06F9/30018 ,  G06F9/30025 ,  G06F9/30032 ,  G06F9/30036 ,  H04L9/0618 ,  H04L63/04 ,  H04L63/0428 ,  H04L63/0435 ,  H04L2209/122

摘要： The present invention provides permutation instructions which can be used in software executed in a programmable processor for solving permutation problems in cryptography, multimedia and other applications. The permute instructions are based on an omega-flip network comprising at least two stages in which each stage can perform the function of either an omega network stage or a flip network stage. Intermediate sequences of bits are defined that an initial sequence of bits from a source register are transformed into. Each intermediate sequence of bits is used as input to a subsequent permutation instruction. Permutation instructions are determined for permuting the initial source sequence of bits into one or more intermediate sequence of bits until a desired sequence is obtained. The intermediate sequences of bits are determined by configuration bits. The permutation instructions form a permutation instruction sequence, of at least one instruction. At most 21 gr/m permutation instructions are used in the permutation instruction sequence, where r is the number of k-bit subwords to be permuted, and m is the number of network stages executed in one instruction. The permutation instructions can be used to permute k-bit subwords packed into an n-bit word, where k can be 1, 2, . . . , or n bits, and k*r=n.

摘要翻译： 本发明提供了可用于在可编程处理器中执行的用于解密密码学，多媒体和其他应用中的置换问题的软件中的置换指令。 置换指令基于包括至少两个阶段的ω-翻转网络，其中每个阶段可以执行ω网络阶段或翻转网络阶段的功能。 定义位的中间序列，来自源寄存器的初始位序列被转换成。 每个中间位数序列用作后续排列指令的输入。 确定排列指令以将比特的初始源序列置换成一个或多个中间比特序列，直到获得期望的序列。 位的中间序列由配置位确定。 置换指令形成至少一条指令的置换指令序列。 在排列指令序列中使用最多21个字节/ m的置换指令，其中r是要置换的k位子字的数量，m是在一个指令中执行的网络级数。 置换指令可用于置换打包成n位字的k位子词，其中k可以是1,2。 。 。 ，或n位，并且k * r = n。

公开(公告)号：US06858579B2

公开(公告)日：2005-02-22

申请号：US09759484

申请日：2001-01-12

申请人： Mauro Perritti ,  Roderick Flower

发明人： Mauro Perritti ,  Roderick Flower

IPC分类号： A61K38/00 ,  C07K14/47 ,  C07K14/00

CPC分类号： C07K14/4721 ,  A61K38/00

摘要： According to the present invention, there is provided a compound comprising the amino acid sequence AMVSE, wherein said compound does not comprise the amino acid sequence EQEYVQTV. Preferably the compound contains 5-11 amino acids. The compound is used in the manufacture of a medicament or pharmaceutical composition for inhibiting leukocyte migration, or treating or preventing inflammation and/or inflammatory response/disease from such conditions as gout, gouty arthritis, rheumatoid arthritis, asthma, reperfusion injury or damage, stroke, myocardial infarction, septic shock, or a skin disorder.

摘要翻译： 根据本发明，提供了包含氨基酸序列AMVSE的化合物，其中所述化合物不包含氨基酸序列EQEYVQTV。 该化合物优选含有5-11个氨基酸。 该化合物用于制造用于抑制白细胞迁移，或治疗或预防诸如痛风，痛风性关节炎，类风湿性关节炎，哮喘，再灌注损伤或损伤，中风等疾病的炎症和/或炎症反应/疾病的药物或药物组合物 ，心肌梗塞，败血性休克或皮肤病症。

公开(公告)号：US06848501B2

公开(公告)日：2005-02-01

申请号：US10356428

申请日：2003-01-31

申请人： Harunori Hirao ,  Yukihiro Matsumoto ,  Sei Nakahara ,  Osamu Dodo ,  Tetsuji Mitsumoto ,  Takeshi Nishimura ,  Kazuhiko Sakamoto ,  Hiroo Iwato

发明人： Harunori Hirao ,  Yukihiro Matsumoto ,  Sei Nakahara ,  Osamu Dodo ,  Tetsuji Mitsumoto ,  Takeshi Nishimura ,  Kazuhiko Sakamoto ,  Hiroo Iwato

IPC分类号： B01J19/00 ,  F28D7/16 ,  F28D9/00 ,  F28F19/00 ,  F28F27/02

CPC分类号： F28D9/0068 ,  B01J19/002 ,  B01J2219/00252 ,  F28D7/1607 ,  F28D7/1623 ,  F28D9/0062 ,  F28F9/0278 ,  F28F19/00 ,  F28F2250/102

摘要： In an apparatus provided with a plate type heat exchanger as a heater and/or a cooler and operated to treat a gas containing an easily blocking substance, a method for preventing the plate type heat exchanger from being blocked is disclosed which is characterized by i) setting the width of a flow path on a plate of the plate type heat exchanger in the apparatus in a range of 6-25 mm and ii) setting the average flow rate of the gas passing the plate type heat exchanger in the apparatus per unit cross-sectional area of the flow path on the plate in the range of 3-15 m/s. In the exchange of heat of an easily blocking substance by the use of a plate type heat exchanger, a method for preventing the plate type heat exchanger from blockage is disclosed which has the plate type heat exchanger provided in the port for introducing a gas containing an easily blocking substance with a gas dispersion plate. This invention, in the heat exchange of an effluent gas emanating from a process for the production of (meth)acrylic acid or an ester thereof or the disposal of the gas, significantly allays blockage of the interior of the plate type heat exchanger.

摘要翻译： 在设置有作为加热器和/或冷却器的板式热交换器并且被操作以处理含有易阻塞物质的气体的装置中，公开了一种防止板式热交换器被堵塞的方法，其特征在于i） 将设备中板式热交换器的板上的流路宽度设置在6-25mm的范围内，以及ii）将通过板式热交换器的气体的平均流量设置在每单位十字的装置中 板上流路的截面面积在3-15 m / s的范围内。 在通过使用板式热交换器交换容易堵塞物质的热的情况下，公开了一种防止板式热交换器堵塞的方法，其具有设置在用于引入含有 用气体分散板容易地堵塞物质。 本发明在从（甲基）丙烯酸或其酯的制备方法产生的流出气体的热交换或气体的处理中显着地阻止了板式热交换器的内部堵塞。

公开(公告)号：US06921653B2

公开(公告)日：2005-07-26

申请号：US09829275

申请日：2001-04-09

申请人： Suzanne Walker ,  Sha Ha

发明人： Suzanne Walker ,  Sha Ha

IPC分类号： C12N9/10

CPC分类号： C12N9/1048 ,  Y02A90/26

摘要： The present invention relates to crystals of the Escherichia coli MurG, a membrane-associated UDP-glycosyltransferase involved in peptidoglycan biosynthesis. The present invention also relates to three-dimensional atomic coordinates of the MurG protein, three-dimensional structures of the protein, and images thereof. The present invention relates to methods of crystallizing MurG proteins.

摘要翻译： 本发明涉及大肠杆菌MurG的晶体，其涉及肽聚糖生物合成的膜相关的UDP-糖基转移酶。 本发明还涉及MurG蛋白质的三维原子坐标，蛋白质的三维结构及其图像。 本发明涉及使MurG蛋白结晶的方法。

公开(公告)号：US06919770B2

公开(公告)日：2005-07-19

申请号：US10620159

申请日：2003-07-15

申请人： William Happer ,  Daniel K. Walter

发明人： William Happer ,  Daniel K. Walter

IPC分类号： G04F5/14 ,  H03L7/26

CPC分类号： G04F5/14

摘要： The present invention relates to a method and system for using end resonances of highly spin-polarized alkali metal vapors for an atomic clock, magnetometer or other system. A left end resonance involves a transition from the quantum state of minimum spin angular momentum along the direction of the magnetic field. A right end resonance involves a transition from the quantum state of maximum spin angular momentum along the direction of the magnetic field. For each quantum state of extreme spin there are two end resonances, a microwave resonance and a Zeeman resonance. The microwave resonance is especially useful for atomic clocks, but it can also be used in magnetometers. The low frequency Zeeman resonance is useful for magnetometers.

摘要翻译： 本发明涉及一种用于原子钟，磁强计或其他系统的高自旋极化碱金属蒸汽的端部共振的方法和系统。 左端共振涉及从磁场方向的最小自旋角动量的量子态的转变。 右端共振涉及从磁场方向的最大自旋角动量的量子态的转变。 对于极端自旋的每个量子态，存在两个端部谐振，微波谐振和塞曼谐振。 微波谐振对原子钟特别有用，但它也可用于磁力计。 低频塞曼谐振对磁力计有用。

公开(公告)号：US06873215B2

公开(公告)日：2005-03-29

申请号：US10629138

申请日：2003-07-28

申请人： Christopher Andrew Devries ,  Ralph Dickson Mason

发明人： Christopher Andrew Devries ,  Ralph Dickson Mason

IPC分类号： G06F1/04 ,  G06F1/14 ,  G06F1/32 ,  H03L3/00 ,  H04B1/16 ,  G01R23/00 ,  H03B5/04 ,  H03L7/00

CPC分类号： G06F1/3246 ,  G06F1/14 ,  G06F1/3228

摘要： A power down system and method for an integrated circuit that enables a power down mode to be maintained for a predetermined time is described herein. The power down system comprises an oscillator, a low power oscillator and an oscillator control circuit controlling both the oscillator and the low power oscillator. The oscillator control circuit including at least one real time counter. The oscillator control circuit being so configured that the oscillator is energized when said oscillator control circuit is in a normal mode and that, when a power down signal is received: a) the oscillator control circuit measures an oscillation frequency of the low power oscillator, b) the oscillator control circuit uses the measured oscillation frequency of the low power oscillator to set the real time counter so as to maintain the power down mode for the predetermined time, c) the oscillator control circuit turns off the oscillator and uses the low power oscillator for the duration of the power down.

摘要翻译： 这里描述了一种用于使得能够将停电模式保持预定时间的集成电路的掉电系统和方法。 断电系统包括振荡器，低功率振荡器和控制振荡器和低功率振荡器的振荡器控制电路。 该振荡器控制电路包括至少一个实时计数器。 振荡器控制电路被配置成当所述振荡器控制电路处于正常模式时振荡器被通电，并且当接收到掉电信号时：振荡器控制电路测量低功率振荡器的振荡频率，b ）振荡器控制电路使用测量的低功率振荡器的振荡频率来设置实时计数器，以便在预定时间内保持掉电模式，c）振荡器控制电路关闭振荡器并使用低功率振荡器 在掉电期间。

公开(公告)号：US06871583B2

公开(公告)日：2005-03-29

申请号：US10726089

申请日：2003-12-02

申请人： Fred G. Devlin, III ,  Robert Proniewski

发明人： Fred G. Devlin, III ,  Robert Proniewski

IPC分类号： B60C19/00 ,  B29B17/00 ,  B29K21/00 ,  B65B27/06 ,  B30B15/00

CPC分类号： B30B9/30 ,  B29B17/0047 ,  B29K2021/00 ,  B29L2030/00 ,  Y02W30/62

摘要： The method of the present invention for handling scrap tires, includes a step of providing a compacting apparatus to a scrap tire generator, such as a tire retailer. Before compacting the tires, the tire can be marked with a unique identifier assigned to every tire generator. By marking the scrap tires with a unique identifier, the scrap tires can be tracked on their way to the final destination. The compacting apparatus provides volume reduction of the scrap tires individually into a form that can have a reduction of at least fifty percent of original cubic volume. The tires can be pinched to maintain the compacted tire in the compacted form and prevent the compacted tire from regaining its original shape. The compacted scrap tires can be accumulated inside a tire collection enclosure, such as a trailer or dumpster. The collected tires can be transported with much more weight efficient loads of the tires to a transfer station, a recycling facility, or an end user.

摘要翻译： 用于处理废旧轮胎的本发明的方法包括向轮胎零件商等废轮胎发电机提供压实装置的步骤。 在对轮胎进行压实之前，轮胎可以被标记为分配给每个轮胎发电机的唯一标识符。 通过用独特的标识符标记废轮胎，可以在到达最终目的地的路上跟踪废轮胎。 压实装置将废轮的体积减小分别提供成可以减少原始立方体积的至少百分之五十的形式。 轮胎可以被挤压以将压实的轮胎保持在压实形式中，并且防止压实轮胎恢复其原始形状。 压实的废轮胎可以积聚在轮胎收集箱内，例如拖车或垃圾箱。 所收集的轮胎可以以更高的重量的轮胎负载运送到转运站，回收设施或最终用户。

公开(公告)号：US06870066B2

公开(公告)日：2005-03-22

申请号：US10385359

申请日：2003-03-10

申请人： Fumio Shibusawa ,  Naoki Serata ,  Kazuhiko Sakamoto

发明人： Fumio Shibusawa ,  Naoki Serata ,  Kazuhiko Sakamoto

IPC分类号： C07B61/00 ,  C07C51/09 ,  C07C51/377 ,  C07C51/487 ,  C07C57/04 ,  C07C67/28 ,  C07C67/30 ,  C07C67/327 ,  C07C67/60 ,  C07C69/54 ,  C07C69/73 ,  C07C57/18

CPC分类号： C07C67/327 ,  C07C51/09 ,  C07C51/377 ,  C07C51/487 ,  C07C67/60 ,  C07C57/04 ,  C07C69/54

摘要： A method for the decomposition of a Michael type adduct of an acrylic acid and/or an acrylic ester represented by the following formula [I] or [II] is disclosed, wherein decomposing the Michael type adduct in the presence of at least one copper salt and at least one metal salt selected from the group consisting of an alkali metal salt and an alkaline earth metal salt into an acrylic acid and/or an acrylic ester and/or an alcohol. CH2═CHCOO(—X—COO)n—R1  [I] R2—O(—X—COO)m—R3  [II] (wherein n and m denote an integer in the range of 1-5, R1, R2, and R3 independently denote a hydrogen atom or an alkyl group, and —X— denotes —CH2CH2— or —CH(CH3)—, and —X— may be identical or different when n is 2 or more).

摘要翻译： 公开了分解由下式[I]或[II]表示的丙烯酸和/或丙烯酸酯的迈克尔型加合物的方法，其中在至少一种铜盐存在下分解迈克尔型加合物 和选自碱金属盐和碱土金属盐的至少一种金属盐转化成丙烯酸和/或丙烯酸酯和/或醇（其中n和m表示在 1-5，R 1，R 2和R 3独立地表示氢原子或烷基，-X-表示-CH 2 CH 2 - 或-CH（CH 3） - ，-X-可以 当n为2以上时，相同或不同）。