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公开(公告)号：US5762878A
公开(公告)日：1998-06-09
申请号：US713553
申请日：1996-09-09
申请人： Frederick L. Clark , Kendall B. Hendrick , Richard R. Martin , Larry W. Moore , William J. Raymoure , Paul R. Schrier , Edna S. Walker , Donny Ray Walker , Gary E. Winter , Kevin M. Cloonan , David A. Yost , John M. Clemens , William J. Kanewske, III , Douglas D. McDowell , Carl M. Oleksak , William D. Rumbaugh , B. Jane Smith , James A. Vaught , Apparao Tayi , Robert A. Wohlford , James E. Mitchell , Robert B. Hance , Peter A. Lagocki , Richard A. Merriam , Charles D. Pennington , Linda S. Schmidt , Adrian M. Spronk , Richard L. Vickstrom , William E. Watkins, III , Gilbert Clift , Alyn K. Stanton , David B. Hills
发明人： Frederick L. Clark , Kendall B. Hendrick , Richard R. Martin , Larry W. Moore , William J. Raymoure , Paul R. Schrier , Edna S. Walker , Donny Ray Walker , Gary E. Winter , Kevin M. Cloonan , David A. Yost , John M. Clemens , William J. Kanewske, III , Douglas D. McDowell , Carl M. Oleksak , William D. Rumbaugh , B. Jane Smith , James A. Vaught , Apparao Tayi , Robert A. Wohlford , James E. Mitchell , Robert B. Hance , Peter A. Lagocki , Richard A. Merriam , Charles D. Pennington , Linda S. Schmidt , Adrian M. Spronk , Richard L. Vickstrom , William E. Watkins, III , Gilbert Clift , Alyn K. Stanton , David B. Hills
IPC分类号： B01F11/00 , B01L3/00 , B01L3/08 , B01L9/06 , B29C45/00 , G01N1/00 , G01N21/03 , G01N21/25 , G01N21/64 , G01N21/76 , G01N33/53 , G01N33/537 , G01N33/538 , G01N33/542 , G01N33/543 , G01N35/00 , G01N35/02 , G01N35/04 , G01N35/10 , H01J49/04
CPC分类号： B01F11/0022 , B01L3/08 , B01L3/5025 , B01L3/50853 , B29C45/00 , G01N21/03 , G01N21/253 , G01N21/6445 , G01N21/645 , G01N21/76 , G01N33/53 , G01N33/5302 , G01N33/537 , G01N33/538 , G01N33/542 , G01N33/54313 , G01N35/0092 , G01N35/025 , H01J49/04 , B01L2200/142 , B01L2300/042 , B01L2300/043 , B01L3/5085 , B01L9/06 , B29K2995/0032 , B29L2023/22 , G01N2001/007 , G01N2021/6482 , G01N2035/00168 , G01N2035/00287 , G01N2035/00356 , G01N2035/00386 , G01N2035/00455 , G01N2035/00475 , G01N2035/00495 , G01N2035/00524 , G01N2035/00752 , G01N2035/0093 , G01N2035/0405 , G01N2035/0436 , G01N2035/0441 , G01N2035/0443 , G01N2035/0444 , G01N2035/0446 , G01N2035/0448 , G01N2035/0453 , G01N2035/0465 , G01N2035/1025 , G01N2035/1076 , G01N2035/1086 , G01N35/0099 , G01N35/1004 , G01N35/1065 , Y10S215/03 , Y10T436/11 , Y10T436/113332
摘要： A sample container segment assembly for use in an automated, continuous, and random access analytical system is disclosed. The assembly includes a sample container which is received by a sample container segment, and the sample container segment is received on a carousel of the automated analytical instrument. The test sample container includes an upper skirt and a body having a reservoir for receipt of the test sample. The segment includes a base, a frame, and a handle. The frame has a shelf for which the upper skirt of the test sample container rests on, and has openings for receipt of the body of the sample container. The carousel has a carousel trough for receipt of the base of the sample container segment, and has a plurality of alignment pins disposed in the carousel trough. The base of the sample container segment has a circular slot and an elongated slot for receiving the alignment pins and positioning the sample container segment relative to the carousel. The sample container segment can include a liquid level sensing sleeve which is made of a conductive material and surrounds the reservoir of the test sample container inserted therein. Alternatively, the test sample container can have a conductive core which surrounds the reservoir and extends therebelow. The container sample segment can also include various sleeves, or springs and arms, for securing and positioning the test sample container within the sample container segment.
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公开(公告)号：US5578494A
公开(公告)日：1996-11-26
申请号：US600321
申请日：1996-02-13
申请人： Frederic L. Clark , Kendall B. Hendrick , Richard R. Martin , Larry W. Moore , William J. Raymoure , Paul R. Schrier , Edna S. Walker , Donny R. Walker , Gary E. Winter , Kevin M. Cloonan , David A. Yost , John M. Clemens , William J. Kanewske, III , Douglas D. McDowell , Carl M. Oleksak , William D. Rumbaugh , B. Jane Smith , James A. Vaught , Apparao Tayi , Robert A. Wohlford , James E. Mitchell , Robert B. Hance , Peter A. Lagocki , Richard A. Merriam , Charles D. Pennington , Linda S. Schmidt , Adrian M. Spronk , Richard L. Vickstrom , William E. Watkins, III , Gilbert Clift , Alyn K. Stanton , David B. Hills
发明人： Frederic L. Clark , Kendall B. Hendrick , Richard R. Martin , Larry W. Moore , William J. Raymoure , Paul R. Schrier , Edna S. Walker , Donny R. Walker , Gary E. Winter , Kevin M. Cloonan , David A. Yost , John M. Clemens , William J. Kanewske, III , Douglas D. McDowell , Carl M. Oleksak , William D. Rumbaugh , B. Jane Smith , James A. Vaught , Apparao Tayi , Robert A. Wohlford , James E. Mitchell , Robert B. Hance , Peter A. Lagocki , Richard A. Merriam , Charles D. Pennington , Linda S. Schmidt , Adrian M. Spronk , Richard L. Vickstrom , William E. Watkins, III , Gilbert Clift , Alyn K. Stanton , David B. Hills
IPC分类号： B01F11/00 , B01L3/00 , B01L3/08 , B01L9/06 , B29C45/00 , G01N1/00 , G01N21/03 , G01N21/25 , G01N21/64 , G01N21/76 , G01N33/53 , G01N33/537 , G01N33/538 , G01N33/542 , G01N33/543 , G01N35/00 , G01N35/02 , G01N35/04 , G01N35/10 , H01J49/04 , B65D51/04
CPC分类号： B01L3/08 , B01F11/0022 , B01L3/5025 , B01L3/50853 , B29C45/00 , G01N21/03 , G01N21/253 , G01N21/645 , G01N21/76 , G01N33/53 , G01N33/5302 , G01N33/537 , G01N33/538 , G01N33/542 , G01N33/54313 , G01N35/0092 , G01N35/025 , H01J49/04 , B01L2200/142 , B01L2300/042 , B01L2300/043 , B01L3/5085 , B01L9/06 , B29K2995/0032 , B29L2023/22 , G01N2001/007 , G01N2021/6482 , G01N2035/00168 , G01N2035/00287 , G01N2035/00356 , G01N2035/00386 , G01N2035/00455 , G01N2035/00475 , G01N2035/00495 , G01N2035/00524 , G01N2035/00752 , G01N2035/0093 , G01N2035/0405 , G01N2035/0436 , G01N2035/0441 , G01N2035/0443 , G01N2035/0444 , G01N2035/0446 , G01N2035/0448 , G01N2035/0453 , G01N2035/0465 , G01N2035/1025 , G01N2035/1076 , G01N2035/1086 , G01N35/0099 , G01N35/1004 , G01N35/1065 , Y10T436/11 , Y10T436/113332 , Y10T436/119163
摘要： The present invention is a method for opening and closing a cap pivotally mounted on a container for storing reagents for use in an automated analytical instrument. The cap has one end for sealing the container and a tab extending from the other end for pivoting the cap. The method comprises the steps of positioning a closed container adjacent an actuating device mounted on the analytical system. The method further comprises the steps of projecting the actuating device against the top of the tab to pivotally open the cap to a position sufficiently vertical for aspirating reagent from the container, and retracting the actuating device from the cap to a position above the pivotal mounting thereof. The method comprises the final step of causing relative motion between the cap and the actuating device so that the actuating device drags along the top of the cap pivotally closing the cap to provide a sufficient seal on the container preventing evaporation of the reagent therefrom.
摘要翻译： 本发明是一种用于打开和关闭枢转地安装在用于存储用于自动分析仪器的试剂的容器上的盖的方法。 盖具有用于密封容器的一端和从另一端延伸以突出盖的突片。 该方法包括以下步骤：将密封容器定位在安装在分析系统上的致动装置附近。 该方法还包括以下步骤：将致动装置突出于突片的顶部，以将帽旋转到足够垂直的位置以从容器吸出试剂，并将致动装置从帽缩回到其枢转安装件上方的位置 。 该方法包括在帽和致动装置之间引起相对运动的最后步骤，使得致动装置沿着盖的顶部拖动，枢转地闭合盖，以在容器上提供足够的密封，防止试剂从其中蒸发。
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公开(公告)号：US5575978A
公开(公告)日：1996-11-19
申请号：US176551
申请日：1994-01-03
申请人： Frederick L. Clark , Kendall B. Hendrick , Richard R. Martin , Larry W. Moore , William J. Raymoure , Paul R. Schrier , Edna S. Walker , Donny R. Walker , Gary E. Winter , Kevin M. Cloonan , David A. Yost , John M. Clemens , William J. Kanewske, III , Douglas D. McDowell , Carl M. Oleksak , William D. Rumbaugh , B. Jane Smith , James A. Vaught , Apparao Tayi , Robert A. Wohlford , James E. Mitchell , Robert B. Hance , Peter A. Lagocki , Richard A. Merriam , Charles D. Pennington , Linda S. Schmidt , Adrian M. Spronk , Richard L. Vickstrom , William E. Watkins, III , Gilbert Clift , Alyn K. Stanton , David B. Hills
发明人： Frederick L. Clark , Kendall B. Hendrick , Richard R. Martin , Larry W. Moore , William J. Raymoure , Paul R. Schrier , Edna S. Walker , Donny R. Walker , Gary E. Winter , Kevin M. Cloonan , David A. Yost , John M. Clemens , William J. Kanewske, III , Douglas D. McDowell , Carl M. Oleksak , William D. Rumbaugh , B. Jane Smith , James A. Vaught , Apparao Tayi , Robert A. Wohlford , James E. Mitchell , Robert B. Hance , Peter A. Lagocki , Richard A. Merriam , Charles D. Pennington , Linda S. Schmidt , Adrian M. Spronk , Richard L. Vickstrom , William E. Watkins, III , Gilbert Clift , Alyn K. Stanton , David B. Hills
IPC分类号： B01F11/00 , B01L3/00 , B01L3/08 , B01L9/06 , B29C45/00 , G01N1/00 , G01N21/03 , G01N21/25 , G01N21/64 , G01N21/76 , G01N33/53 , G01N33/537 , G01N33/538 , G01N33/542 , G01N33/543 , G01N35/00 , G01N35/02 , G01N35/04 , G01N35/10 , H01J49/04
CPC分类号： B01F11/0022 , B01L3/08 , B01L3/5025 , B01L3/50853 , B29C45/00 , G01N21/03 , G01N21/253 , G01N21/6445 , G01N21/645 , G01N21/76 , G01N33/53 , G01N33/5302 , G01N33/537 , G01N33/538 , G01N33/542 , G01N33/54313 , G01N35/0092 , G01N35/025 , H01J49/04 , B01L2200/142 , B01L2300/042 , B01L2300/043 , B01L3/5085 , B01L9/06 , B29K2995/0032 , B29L2023/22 , G01N2001/007 , G01N2021/6482 , G01N2035/00168 , G01N2035/00287 , G01N2035/00356 , G01N2035/00386 , G01N2035/00455 , G01N2035/00475 , G01N2035/00495 , G01N2035/00524 , G01N2035/00752 , G01N2035/0093 , G01N2035/0405 , G01N2035/0436 , G01N2035/0441 , G01N2035/0443 , G01N2035/0444 , G01N2035/0446 , G01N2035/0448 , G01N2035/0453 , G01N2035/0465 , G01N2035/1025 , G01N2035/1076 , G01N2035/1086 , G01N35/0099 , G01N35/1004 , G01N35/1065 , Y10S215/03 , Y10T436/11 , Y10T436/113332
摘要： A sample container segment assembly for use in an automated, continuous, and random access analytical system is disclosed. The assembly includes a sample container which is received by a sample container segment, and the sample container segment is received on a carousel of the automated analytical instrument. The test sample container includes an upper skirt and a body having a reservoir for receipt of the test sample. The segment includes a base, a frame, and a handle. The frame has a shelf for which the upper skirt of the test sample container rests on, and has openings for receipt of the body of the sample container. The carousel has a carousel trough for receipt of the base of the sample container segment, and has a plurality of alignment pins disposed in the carousel trough. The base of the sample container segment has a circular slot and an elongated slot for receiving the alignment pins and positioning the sample container segment relative to the carousel. The sample container segment can include a liquid level sensing sleeve which is made of a conductive material and surrounds the reservoir of the test sample container inserted therein. Alternatively, the test sample container can have a conductive core which surrounds the reservoir and extends therebelow. The container sample segment can also include various sleeves, or springs and arms, for securing and positioning the test sample container within the sample container segment.
摘要翻译： 公开了一种用于自动化，连续和随机存取分析系统的样品容器段组件。 组件包括由样品容器段接收的样品容器，并且样品容器段被接收在自动分析仪器的转盘上。 测试样本容器包括上裙部和具有用于接收测试样品的容器的主体。 该段包括基座，框架和手柄。 框架具有搁置测试样本容器的上裙部的搁架，并且具有容纳样本容器的主体的开口。 转盘具有用于接收样品容器段的底部的转盘槽，并且具有设置在转盘槽中的多个对准销。 样品容器段的底部具有圆形狭槽和用于接收对准销并且相对于转盘定位样品容器段的细长槽。 样品容器段可包括由导电材料制成并围绕插入其中的测试样品容器的储存器的液位感测套筒。 或者，测试样本容器可以具有包围储存器并在其下方延伸的导电芯。 容器样品片段还可以包括各种套筒或弹簧和臂，用于将测试样品容器固定并定位在样品容器段内。
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公开(公告)号：US5635364A
公开(公告)日：1997-06-03
申请号：US176173
申请日：1994-01-03
申请人： Frederick L. Clark , Kendall B. Hendrick , Richard R. Martin , Larry W. Moore , William J. Raymoure , Paul R. Schrier , Edna S. Walker , Donny R. Walker , Gary E. Winter , Kevin M. Cloonan , David A. Yost , John M. Clemens , William J. Kanewske, III , Douglas D. McDowell , Carl M. Oleksak , William D. Rumbaugh , B. Jane Smith , James A. Vaught , Apparao Tayi , Robert A. Wohlford , James E. Mitchell , Robert B. Hance , Peter A. Lagocki , Richard A. Merriam , Charles D. Pennington , Linda S. Schmidt , Adrian M. Spronk , Richard L. Vickstrom , William E. Watkins, III , Gilbert Clift , Alyn K. Stanton , David B. Hills
发明人： Frederick L. Clark , Kendall B. Hendrick , Richard R. Martin , Larry W. Moore , William J. Raymoure , Paul R. Schrier , Edna S. Walker , Donny R. Walker , Gary E. Winter , Kevin M. Cloonan , David A. Yost , John M. Clemens , William J. Kanewske, III , Douglas D. McDowell , Carl M. Oleksak , William D. Rumbaugh , B. Jane Smith , James A. Vaught , Apparao Tayi , Robert A. Wohlford , James E. Mitchell , Robert B. Hance , Peter A. Lagocki , Richard A. Merriam , Charles D. Pennington , Linda S. Schmidt , Adrian M. Spronk , Richard L. Vickstrom , William E. Watkins, III , Gilbert Clift , Alyn K. Stanton , David B. Hills
IPC分类号： B01F11/00 , B01L3/00 , B01L3/08 , B01L9/06 , B29C45/00 , G01N1/00 , G01N21/03 , G01N21/25 , G01N21/64 , G01N21/76 , G01N33/53 , G01N33/537 , G01N33/538 , G01N33/542 , G01N33/543 , G01N35/00 , G01N35/02 , G01N35/04 , G01N35/10 , H01J49/04 , G01N33/546
CPC分类号： B01F11/0022 , B01L3/08 , B01L3/5025 , B01L3/50853 , B29C45/00 , G01N21/03 , G01N21/253 , G01N21/645 , G01N21/76 , G01N33/53 , G01N33/5302 , G01N33/537 , G01N33/538 , G01N33/542 , G01N33/54313 , G01N35/0092 , G01N35/025 , H01J49/04 , B01L2200/142 , B01L2300/042 , B01L2300/043 , B01L3/5085 , B01L9/06 , B29K2995/0032 , B29L2023/22 , G01N2001/007 , G01N2021/6482 , G01N2035/00168 , G01N2035/00287 , G01N2035/00356 , G01N2035/00386 , G01N2035/00455 , G01N2035/00475 , G01N2035/00495 , G01N2035/00524 , G01N2035/00752 , G01N2035/0093 , G01N2035/0405 , G01N2035/0436 , G01N2035/0441 , G01N2035/0443 , G01N2035/0444 , G01N2035/0446 , G01N2035/0448 , G01N2035/0453 , G01N2035/0465 , G01N2035/1025 , G01N2035/1076 , G01N2035/1086 , G01N35/0099 , G01N35/1004 , G01N35/1065 , Y10S435/962 , Y10S435/967 , Y10S436/805 , Y10T436/11
摘要： A method for verifying that an assay methodology is properly performed, that assay reagents employed possess the necessary potency for accurately performing such assay methodology, and whether or not test samples or assay reagents have been tampered with or are adulterated, is described. The method is performed by employing an assay verification sample, comprising a positive analyte component and the test sample under analysis, wherein the assay verification sample is analyzed employing the same assay reagents and essentially the same assay methodology employed to analyze the test sample. The method is particularly useful for performing heterogeneous immunoassays on an automated continuous and random access analytical system.
摘要翻译： 描述了用于验证测定方法被适当地进行的方法，所用的测定试剂具有用于精确地进行这种测定方法学的必要的效力，以及测试样品或测定试剂是否被篡改或掺杂。 该方法通过采用包含正分析物组分和待分析的测试样品的测定验证样品进行，其中使用相同的测定试剂和用于分析测试样品的基本相同的测定方法分析测定验证样品。 该方法对于在自动连续和随机存取分析系统上进行异质免疫测定特别有用。
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公开(公告)号：US5610069A
公开(公告)日：1997-03-11
申请号：US549020
申请日：1995-10-27
申请人： Frederick L. Clark , Kendall B. Hendrick , Richard R. Martin , Larry W. Moore , William J. Raymoure , Paul R. Schrier , Edna S. Walker , Donny R. Walker , Gary E. Winter , Kevin M. Cloonan , David A. Yost , John M. Clemens , William J. Kanewske, III , Douglas D. McDowell , Carl M. Oleksak , William D. Rumbaugh , B. Jane Smith , James A. Vaught , Apparao Tayi , Robert A. Wohlford , James E. Mitchell , Robert B. Hance , Peter A. Lagocki , Richard A. Merriam , Charles D. Pennington , Linda S. Schmidt , Adrian M. Spronk , Richard L. Vickstrom , William E. Watkins, III , Gilbert Clift , Alyn K. Stanton , David B. Hills
发明人： Frederick L. Clark , Kendall B. Hendrick , Richard R. Martin , Larry W. Moore , William J. Raymoure , Paul R. Schrier , Edna S. Walker , Donny R. Walker , Gary E. Winter , Kevin M. Cloonan , David A. Yost , John M. Clemens , William J. Kanewske, III , Douglas D. McDowell , Carl M. Oleksak , William D. Rumbaugh , B. Jane Smith , James A. Vaught , Apparao Tayi , Robert A. Wohlford , James E. Mitchell , Robert B. Hance , Peter A. Lagocki , Richard A. Merriam , Charles D. Pennington , Linda S. Schmidt , Adrian M. Spronk , Richard L. Vickstrom , William E. Watkins, III , Gilbert Clift , Alyn K. Stanton , David B. Hills
IPC分类号： B01F11/00 , B01L3/00 , B01L3/08 , B01L9/06 , B29C45/00 , G01N1/00 , G01N21/03 , G01N21/25 , G01N21/64 , G01N21/76 , G01N33/53 , G01N33/537 , G01N33/538 , G01N33/542 , G01N33/543 , G01N35/00 , G01N35/02 , G01N35/04 , G01N35/10 , H01J49/04
CPC分类号： G01N35/0092 , B01F11/0022 , B01L3/08 , B01L3/5025 , B01L3/50853 , B29C45/00 , G01N21/03 , G01N21/6445 , G01N21/76 , G01N33/53 , G01N33/5302 , G01N33/537 , G01N33/538 , G01N33/542 , G01N33/54313 , G01N35/025 , H01J49/04 , B01L2200/142 , B01L2300/042 , B01L2300/043 , B01L3/5085 , B01L9/06 , B29K2995/0032 , B29L2023/22 , G01N2001/007 , G01N2021/6482 , G01N2035/00168 , G01N2035/00287 , G01N2035/00356 , G01N2035/00386 , G01N2035/00455 , G01N2035/00475 , G01N2035/00495 , G01N2035/00524 , G01N2035/00752 , G01N2035/0093 , G01N2035/0405 , G01N2035/0436 , G01N2035/0441 , G01N2035/0443 , G01N2035/0444 , G01N2035/0446 , G01N2035/0448 , G01N2035/0453 , G01N2035/0465 , G01N2035/1025 , G01N2035/1076 , G01N2035/1086 , G01N35/0099 , G01N35/1004 , G01N35/1065 , Y10T436/114998 , Y10T436/115831 , Y10T436/12
摘要： A method and apparatus for washing clinical apparatus is disclosed. The apparatus is a device for washing clinical apparatus, wherein the clinical apparatus is employed, at different times, to contain a first test substance during a first testing step and a second test substance during a second testing step subsequent to the first testing step. The apparatus comprises a device for supplying a wash solution to the apparatus, and for varying the quantity of the wash solution supplied to the apparatus. The apparatus further comprises a control unit for controlling the device for varying quantity to vary the quantity of the wash solution in proportion to the potential for contamination between the first test substance and the second test substance contained in the apparatus.
摘要翻译： 公开了一种用于洗涤临床装置的方法和装置。 该装置是用于洗涤临床装置的装置，其中在第一测试步骤之后的第二测试步骤期间，临床装置在不同时间被使用以在第一测试步骤期间包含第一测试物质和第二测试物质。 该装置包括用于将洗涤溶液供应到该装置并用于改变供应给该装置的洗涤溶液的量的装置。 该装置还包括一个控制单元，用于控制装置的变化量，以便与包含在装置中的第一测试物质和第二测试物质之间的污染可能性成比例地改变洗涤溶液的量。
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