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    Real time FPGA resampling for swept source optical coherence tomography
    1.
    发明授权
    Real time FPGA resampling for swept source optical coherence tomography 有权

    公开(公告)号：US10393502B2

    公开(公告)日：2019-08-27

    申请号：US14809747

    申请日：2015-07-27

    Applicant: Axsun Technologies LLC

    Inventor： Bartley C. Johnson ,  Noble G. Larson ,  Brian Goldberg ,  Mark E. Kuznetsov

    IPC: G01B9/02 ,  A61B5/00

    Abstract: Real-time swept source OCT data is most often sampled using a specially cut hardware k-clock. The present invention involves mathematically resampling signals within an FPGA-based data acquisition board based on data sampled from a wide free spectral range reference interferometer. The FPGA can then multiply up the reference clock rate to achieve greater imaging depth. The Nyquist fold-over depth can thus be programmed from a standard reference to an arbitrary depth, much as PLL frequency synthesizer can produce many frequencies from a standard stable reference. The system is also capable of real-time performance.

    System and method for resampling optical coherence tomography signals in segments
    2.
    发明授权
    System and method for resampling optical coherence tomography signals in segments 有权

    公开(公告)号：US09869542B2

    公开(公告)日：2018-01-16

    申请号：US14257568

    申请日：2014-04-21

    Applicant: Axsun Technologies LLC

    Inventor： Brian Goldberg ,  Bartley C. Johnson

    IPC: G01B9/02

    CPC classification number: G01B9/02083 ,  G01B9/02004 ,  G01B9/02069 ,  G01B9/02091

    Abstract: A system and method for resampling interference datasets of samples in segments, in a swept-source based Optical Coherence Tomography (OCT) system. The resampling is preferably performed within a Field Programmable Gate Array (FPGA) of the OCT system, the FPGA preferably having Fourier-transform based signal processing capabilities such as Fast Fourier Transform (FFT) cores. Resampling the interference datasets in segments provides a flexible approach to resampling that makes efficient use of system resources such as FFT cores. By resampling the interference datasets in segments, the system adjusts to an increased number of resampling points as the imaging depth upon the sample increases. The OCT system then combines the segments using overlapping values of the resampling points between adjacent resampling regions of the resampled segments, and performs Fourier Transform based post-processing on the combined segments to obtain axial profiles of the sample at desired imaging depths.

    Real Time FPGA Resampling for Swept Source Optical Coherence Tomography
    7.
    发明申请
    Real Time FPGA Resampling for Swept Source Optical Coherence Tomography 审中-公开
    扫描源光学相干断层扫描的实时FPGA重采样

    公开(公告)号：US20160025478A1

    公开(公告)日：2016-01-28

    申请号：US14809747

    申请日：2015-07-27

    Applicant: Axsun Technologies LLC

    Inventor： Bartley C. Johnson ,  Noble G. Larson ,  Brian Goldberg ,  Mark E. Kuznetsov

    IPC: G01B9/02

    CPC classification number: G01B9/02067 ,  A61B5/0066 ,  G01B9/02004 ,  G01B9/02041 ,  G01B9/02069 ,  G01B9/02083 ,  G01B9/02091 ,  G01B2290/60

    Abstract: Real-time swept source OCT data is most often sampled using a specially cut hardware k-clock. The present invention involves mathematically resampling signals within an FPGA-based data acquisition board based on data sampled from a wide free spectral range reference interferometer. The FPGA can then multiply up the reference clock rate to achieve greater imaging depth. The Nyquist fold-over depth can thus be programmed from a standard reference to an arbitrary depth, much as PLL frequency synthesizer can produce many frequencies from a standard stable reference. The system is also capable of real-time performance.

    Abstract translation: 实时扫频源OCT数据通常采用特制硬件k时钟进行采样。 本发明涉及在基于FPGA的数据采集板中基于从宽自由光谱范围参考干涉仪采样的数据对数字重采样信号。 然后，FPGA可以乘以参考时钟速率，以实现更大的成像深度。 因此，奈奎斯特折叠深度可以从标准参考编程到任意深度，就像PLL频率合成器可以从标准稳定参考产生许多频率。 该系统还具有实时性能。

    Integrated dual swept source alternating same scan band for OCT medical imaging
    8.
    发明授权
    Integrated dual swept source alternating same scan band for OCT medical imaging 有权
    用于OCT医疗成像的集成双扫扫源交替相同的扫描带

    公开(公告)号：US09574869B2

    公开(公告)日：2017-02-21

    申请号：US14159748

    申请日：2014-01-21

    Applicant: Axsun Technologies LLC

    Inventor： Bartley C. Johnson ,  Walid Atia ,  Mark E. Kuznetsov ,  Dale C. Flanders

    IPC: G01B9/02 ,  H01S3/106 ,  H01S3/23 ,  H01S5/14

    CPC classification number: G01B9/02091 ,  G01B9/02004 ,  G01B9/02007 ,  G01B9/02069 ,  H01S3/1062 ,  H01S3/2383 ,  H01S5/141

    Abstract: An optical coherence analysis system comprising: a first swept source that generates a first optical signal that is tuned over a first spectral scan band, a second swept source that generates a second optical signal that is tuned over a second spectral scan band, a combiner for combining the first optical signal and the second optical signal to form a combined optical signal, an interferometer for dividing the combined optical signal between a reference arm leading to a reference reflector and a sample arm leading to a sample, and a detector system for detecting an interference signal generated from the combined optical signal from the reference arm and from the sample arm.

    Abstract translation: 一种光学相干分析系统，包括：第一扫描光源，其产生在第一光谱扫描带上调谐的第一光信号，产生在第二光谱扫描带上调谐的第二光信号的第二扫描光源， 组合第一光信号和第二光信号以形成组合的光信号;干涉仪，用于将导通到参考反射器的参考臂与通向样本的采样臂之间的组合光信号分开;以及检测器系统，用于检测 由来自参考臂和来自采样臂的组合光信号产生的干扰信号。

    Spectral filtering of k-clock signal in OCT system and method
    10.
    发明授权
    Spectral filtering of k-clock signal in OCT system and method 有权

    公开(公告)号：US09310182B2

    公开(公告)日：2016-04-12

    申请号：US14143303

    申请日：2013-12-30

    Applicant: Axsun Technologies LLC

    Inventor： Brian Goldberg ,  Bartley C. Johnson

    IPC: G01B9/02

    CPC classification number: G01B9/02004 ,  G01B9/02069 ,  G01B9/02091

    Abstract: A system and method for spectral filtering of a k-clock signal in a swept-source Optical Coherence Tomography (“OCT”) system to remove artifacts in the k-clock signal. The system synchronizes sampling of the k-clock and interference signals generated from scanning a sample. Using a filtered k-clock signal, the system resamples an interference dataset of the interference signals. The system then performs Fourier transform based processing upon the resampled interference dataset to yield axial depth images of the sample. The system preferably performs the reconstruction, resampling, and associated Fourier-Domain signal processing in software via a Field Programmable Gate Array (“FPGA”) of a rendering system.

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